Prolonged treatment with imatinib mesylate in patients with advanced chronic myeloid leukemia causes a reduction of bcr/abl mRNA levels independent of cytogenetic responseE Cariani
III Laboratory, Hospital of Brescia, p le Spedali Civili 1, 25123, Brescia, Italy
Ann Hematol 82:333-5. 2003
..These results suggest that bcr/abl mRNA levels may reflect cytogenetic response only during the early phases of imatinib therapy...
Interleukin 28B genotype determination using DNA from different sources: A simple and reliable tool for the epidemiological and clinical characterization of hepatitis CElisabetta Cariani
Clinical Pathology Toxicology, Ospedale Civile S Agostino Estense, Modena, Italy
J Virol Methods 178:235-8. 2011
..85%; p=0.015). These results indicate that the possibility of reliable IL28B genotyping using different DNA sources may represent a useful tool for both clinical research and characterization of patients with hepatitis C...
- Translating pharmacogenetics into clinical practice: interleukin (IL)28B and inosine triphosphatase (ITPA) polymophisms in hepatitis C virus (HCV) infection
Elisabetta Cariani
Clinical Pathology Toxicology, Ospedale Civile S Agostino Estense, Modena, Italy
Clin Chem Lab Med 49:1247-56. 2011
..This review will cover recent reports on the subject, focusing on the potential use of the new genetic markers in the diagnostic algorithm for the stratification of patients for personalized antiviral regimens...
- Immune-mediated hepatitis-associated aplastic anemia caused by the emergence of a mutant hepatitis B virus undetectable by standard assays
Elisabetta Cariani
Department of Experimental and Applied Medicine, Section of Microbiology, University of Brescia, A O Spedali Civili, Brescia, Italy
J Hepatol 46:743-7. 2007
..HBV DNA determination may be necessary to exclude mutant HBV as a cause of HAA, particularly in categories at high risk of mutant selection such as agammaglobulinemic and transplanted patients...
Relationship between pp65 antigenemia levels and real-time quantitative DNA PCR for Human Cytomegalovirus (HCMV) management in immunocompromised patientsElisabetta Cariani
Department of Experimental and Applied Medicine, Section of Microbiology, University of Brescia, and A O Spedali Civili, Brescia, Italy
BMC Infect Dis 7:138. 2007
..The aim of this study was to analyse the relationship between HCMV DNA and pp65 antigenemia levels in order to identify clinically useful threshold values for the management of patients...
- Frequency of hepatitis B virus mutant in asymptomatic hepatitis B virus carriers receiving prophylactic lamivudine during chemotherapy for hematologic malignancies
Anna Maria Pelizzari
UO Ematologia, Spedali Civili, Brescia, Italy
Hematol J 5:325-8. 2004
..In conclusion, among HBV carriers treated with chemotherapy for haematologic malignancies, the emergence of HBV YMMD mutant occurred in 3.1% of prophylactic lamivudine courses and was of little clinical relevance...
- Comparison of commercial and in-house Real-time PCR assays for quantification of Epstein-Barr virus (EBV) DNA in plasma
Francesca Perandin
Department of Experimental and Applied Medicine, Section of Microbiology, University of Brescia, Brescia, Italy
BMC Microbiol 7:22. 2007
..The aim of this study is to compare the performance of two real-time PCR assays for EBV DNA: a commercial kit as the Q-EBV Real-Time System (Q-EBV PCR, Amplimedical, Turin, Italy) and an in-house assay (EBV RQ-PCR)...
- Real-time quantitation of hepatitis B virus (HBV) DNA in tumorous and surrounding tissue from patients with hepatocellular carcinoma
Isabella Zanella
Institute of Chemistry, School of Medicine, University of Brescia, Brescia, Italy
J Med Virol 68:494-9. 2002
..001). These results show that the quantitation of liver HBV DNA by real-time PCR can be useful to understand HBV state in hepatocellular carcinoma and viral interplay in patients with multiple viral infections...
- Immunological and molecular correlates of disease recurrence after liver resection for hepatocellular carcinoma
Elisabetta Cariani
Clinical Pathology Toxicology, Ospedale S Agostino Estense, Modena, Italy
PLoS ONE 7:e32493. 2012
..HCC infiltrate is characterized by the expression of molecules with negative regulatory function that may favor tumor recurrence and poor survival...
- Effectiveness of the biological monitoring of chemical exposure in the workplace: results of a survey in an area of Northern Italy
Rudy Ivan Paredes Alpaca
Workplace Prevention and Safety Service SPSAL, South Area, Azienda Unità Sanitaria Locale Modena, Modena, Italy
Int J Hyg Environ Health 214:121-6. 2011
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- The impairment of CD8 responses limits the selection of escape mutations in acute hepatitis C virus infection
Simona Urbani
Laboratory of Viral Immunopathology, Department of Infectious Diseases and Hepatology, Azienda Ospedaliera di Parma, Parma, Italy
J Immunol 175:7519-29. 2005
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- Association between heterozygosity for HFE gene mutations and hepatitis viruses in hepatocellular carcinoma
Anna Ludovica Fracanzani
Dipartimento Medicina Interna, Ospedale Maggiore IRCCS, Via F Sforza 35, 20122 Milano, Italy
Blood Cells Mol Dis 35:27-32. 2005
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