Research Topics
Genomes and GenesSpecies | Caroline A DavisSummaryAffiliation: York University Country: Canada Publications
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Publications
Sensitivity to the rewarding effects of food and exercise in the eating disordersCaroline Davis
Department of Psychiatry, The University Health Network, and the Faculty of Medicine, University of Toronto, Canada
Compr Psychiatry 43:189-94. 2002....
Sensitivity to reward and body mass index (BMI): evidence for a non-linear relationshipCaroline Davis
Kinesiology and Health Sciences, York University, 343 Bethune College, 4700 Keele Street, Toronto Ont, Canada, M3J 1P3
Appetite 50:43-9. 2008....
Personality and eating behaviors: a case-control study of binge eating disorderCaroline Davis
York University, Toronto, Canada
Int J Eat Disord 41:243-50. 2008..Our purpose was to ascertain whether BED individuals differed in important ways from nonbinging obese adults...
Addictive behaviors and addiction-prone personality traits: Associations with a dopamine multilocus genetic profileCaroline Davis
School of Kinesiology and Health Sciences, York University, Toronto, Canada Electronic address
Addict Behav 38:2306-12. 2013..These data suggest that brain reward processes tend to exert their influence on addiction risk by their role in the development of relatively stable personality traits associated with addictive behaviors...
Binge eating disorder and the dopamine D2 receptor: genotypes and sub-phenotypesCaroline Davis
Kinesiology and Health Sciences, York University, Toronto, Canada M3J1P3
Prog Neuropsychopharmacol Biol Psychiatry 38:328-35. 2012..We investigated the D2 receptors genes (DRD2/ANKK1) and their relation to the BED phenotype and four sub-phenotypes of BED that reflect an enhanced response to positive food stimuli...
The suppression of appetite and food consumption by methylphenidate: the moderating effects of gender and weight status in healthy adultsCaroline Davis
Faculty of Health, York University, Toronto, Canada
Int J Neuropsychopharmacol 15:181-7. 2012....
Evidence that 'food addiction' is a valid phenotype of obesityCaroline Davis
Faculty of Health, York University, 343 Bethune College, 4700 Keele Street, Toronto, Ontario M3J 1P3, Canada
Appetite 57:711-7. 2011....
Reward sensitivity and the D2 dopamine receptor gene: A case-control study of binge eating disorderCaroline Davis
Kinesiology and Health Sciences, York University, Toronto, Canada
Prog Neuropsychopharmacol Biol Psychiatry 32:620-8. 2008..The present study addressed this issue by implementing psychological and biological markers of reward sensitivity in the assessment protocol...
Education level moderates learning on two versions of the Iowa Gambling TaskCaroline Davis
Faculty of Health Sciences, York University, Toronto, Canada
J Int Neuropsychol Soc 14:1063-8. 2008..Conclusions are that education level, among neurologically-normal adults, should be treated as a stratification or matching variable in case-control research using this task...
A psycho-genetic study of associations between the symptoms of binge eating disorder and those of attention deficit (hyperactivity) disorderCaroline Davis
Faculty of Health Sciences, York University, Centre for Addiction and Mental Health, 343 Bethune College, 4700 Keele Street, Toronto, ON, Canada
J Psychiatr Res 43:687-96. 2009..We also assessed the role of the dopamine D3 receptor in ADHD symptoms since the DRD3 gene has been associated with impulsivity and drug addiction - both relevant features of ADHD...
Dopamine for "wanting" and opioids for "liking": a comparison of obese adults with and without binge eatingCaroline A Davis
Department of Kinesiology and Health Sciences, Faculty of Health, York University, Toronto, Ontario, Canada
Obesity (Silver Spring) 17:1220-5. 2009....
Compulsive overeating as an addiction disorder. A review of theory and evidenceCaroline Davis
York University, Faculty of Health Sciences, Centre for Addiction and Mental Health, Toronto, ON, Canada
Appetite 53:1-8. 2009..We have provided some recommendations for treatment modifications that recognize the similarities between treating drug dependence and compulsive overeating...
Psychobiological traits in the risk profile for overeating and weight gainC Davis
Bethune College, York University, Toronto, Ontario, Canada
Int J Obes (Lond) 33:S49-53. 2009..Finally, the role of impulsivity and its links with symptoms of attention deficit/hyperactivity disorder are discussed, as well as their respective roles in the risk profile for obesity...
Immediate pleasures and future consequences. A neuropsychological study of binge eating and obesityCaroline Davis
Department of Kinesiology and Health Sciences, 343 Bethune College, York University, 4700 Keele Street, Toronto, ON M3J1P3, Canada
Appetite 54:208-13. 2010..Interestingly, when education level was added to the models, those with a higher education performed better on both tasks, and the group differences were not significant...
Attention-deficit/hyperactivity disorder: associations with overeating and obesityCaroline Davis
York University, Toronto, Ontario, Canada
Curr Psychiatry Rep 12:389-95. 2010..This view conforms with the well-established evidence that drug use and abuse are substantially higher among those with ADHD than among the general population...
Is human seasonality implicated in the risk profile for obesity?Caroline Davis
Kinesiology and Health Sciences, York University, Toronto, Canada
Eat Behav 11:301-4. 2010..Reasons why seasonality is positively associated with BMI only in men are not immediately apparent. It is possible that other gender-specific risk factors for overeating may contribute to these findings...
Opiates, overeating and obesity: a psychogenetic analysisC Davis
Kinesiology and Health Sciences, Faculty of Health Sciences, York University, 4700 Keele Street, Toronto, Ontario, Canada
Int J Obes (Lond) 35:1347-54. 2011..We also anticipated that these food preferences would be positively associated with binge eating, hedonic eating and emotionally driven eating-patterns of overeating that would, in turn, predict higher body mass index (BMI)...
Psychological factors associated with ratings of portion size: relevance to the risk profile for obesityCaroline Davis
Department of Kinesiology and Health Sciences, York University, 343 Bethune College, 4700 Keele Street, Toronto, Ontario, Canada M3J 1P3
Eat Behav 8:170-6. 2007....
Looking good-family focus on appearance and the risk for eating disordersCaroline Davis
Department of Kinesiology and Health Sciences, York University, Toronto, Ontario, Canada
Int J Eat Disord 35:136-44. 2004..We tested this hypothesis by predicting that proneness to anxiety (neuroticism) and a family appearance focus would relate interactively (after controlling for body size) to a measure of weight preoccupation...
Sensitivity to reward: implications for overeating and overweightCaroline Davis
Kinesiology and Health Sciences, 343 Bethune College, York University, 4700 Keele Street, Toronto, Ont, Canada M3J 1P3
Appetite 42:131-8. 2004..Results also indicate that STR may serve as a risk factor for overeating and overweight, especially in cultures such as ours where palatable, calorically-dense food is plentiful...
Decision-making deficits and overeating: a risk model for obesityCaroline Davis
York University, 343 Bethune College, 4700 Keele Street, Toronto, ON M3J 1P3, Canada
Obes Res 12:929-35. 2004..That is, they choose immediate rewards in the face of future long-term negative consequences...
Female adolescents with anorexia nervosa and their parents: a case-control study of exercise attitudes and behavioursCaroline Davis
Department of Kinesiology and Health Sciences, York University, Toronto, ON, Canada
Psychol Med 35:377-86. 2005..Finally, we expected that the AN parents would be more active and report a greater commitment to exercise than the control parents...
Seasonality and seasonal affective disorder (SAD): an evolutionary viewpoint tied to energy conservation and reproductive cyclesCaroline Davis
York University, 343 Bethune College, 4700 Keele Street, Toronto, ON, Canada M3J 1P3
J Affect Disord 87:3-10. 2005..The adaptive value of such a pattern, and its putative role in natural selection in humans, is also discussed...
Anorexia nervosa with excessive exercise: a phenotype with close links to obsessive-compulsive disorderCaroline Davis
Department of Kinesiology and Health Sciences, York University, Toronto, Ontario, Canada
Psychiatry Res 142:209-17. 2006..Findings support our prediction that AN patients with excessive physical activity constitute a subtype of the disorder with strong links to OCD. Indeed, this phenotype may be a culture-bound variant of OCD...
Not just a pretty face: physical attractiveness and perfectionism in the risk for eating disordersC Davis
Department of Kinesiology and Health Science, York University, Toronto, Ontario, Canada
Int J Eat Disord 27:67-73. 2000..Surprisingly, however, no research has examined the relationship between objective physical beauty and eating pathologies, despite clinical and theoretical reasons to expect a positive relationship between the two...
Dopamine transporter gene (DAT1) associated with appetite suppression to methylphenidate in a case-control study of binge eating disorderCaroline Davis
Department of Kinesiology and Health Sciences, York University, Toronto, ON, Canada
Neuropsychopharmacology 32:2199-206. 2007..The current findings have implications for treatment response to drugs currently in use (or being developed) for the treatment of overeating and overweight...
From motivation to behaviour: a model of reward sensitivity, overeating, and food preferences in the risk profile for obesityCaroline Davis
Department of Kinesiology and Health Sciences, York University, and Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Appetite 48:12-9. 2007....
Associations among overeating, overweight, and attention deficit/hyperactivity disorder: a structural equation modelling approachCaroline Davis
Departments of Kinesiology and Health Science and Psychology, Bethune College, York University, 4700 Keele Street, Toronto, Ontario, Canada M3J 1P3
Eat Behav 7:266-74. 2006..Some recent studies have reported strong links between obesity and ADHD in adults; however, to date, little work has focussed on possible behavioural mechanisms that could account for this association...
Thinness and body shape of Playboy centerfolds from 1978 to 1998P T Katzmarzyk
School of Kinesiology and Health Science, York University, North York, Ontario, Canada
Int J Obes Relat Metab Disord 25:590-2. 2001..Changes in the body weight and shape of Playboy centerfolds over the past two decades (1978-1998) were examined...
The dopamine-4 receptor gene associated with binge eating and weight gain in women with seasonal affective disorder: an evolutionary perspectiveRobert D Levitan
Mood and Anxiety Division, Centre for Addiction and Mental Health, University of Toronto, Department of Psychiatry, 250 College Street, Room 1126, Toronto, Ontario M5T 1R8, Canada
Biol Psychiatry 56:665-9. 2004..In this study, we examined whether binge eating behavior mediated this putative association...
Personality factors and disordered eating in young women with type 1 diabetes mellitusStacey M Pollock-Barziv
Department of Kinesiology and Health Science, Faculty of Graduate Studies, York University University Health Network
Psychosomatics 46:11-8. 2005..g., insulin omission) and poor glycemic control. The results suggest that personality factors are related to disordered eating and poor glycemic control in diabetic women...
A DRD4/BDNF gene-gene interaction associated with maximum BMI in women with bulimia nervosaAllan S Kaplan
Eating Disorders Program, Toronto General Hospital, Toronto, Canada
Int J Eat Disord 41:22-8. 2008....
A birth-season/DRD4 gene interaction predicts weight gain and obesity in women with seasonal affective disorder: A seasonal thrifty phenotype hypothesisRobert D Levitan
Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Toronto, ON, Canada
Neuropsychopharmacology 31:2498-503. 2006..We speculate that these data may reflect the vestigial expression of a seasonal thrifty phenotype that contributed to the positive selection of the 7R allele over the past 40,000 years...
