Research Topics
| Andrea GruneirSummaryAffiliation: Women's College Hospital Country: Canada Publications
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Detail Information
Publications
Frequency and pattern of emergency department visits by long-term care residents--a population-based studyAndrea Gruneir
Women s College Research Institute, Women s College Hospital, Toronto, Canada
J Am Geriatr Soc 58:510-7. 2010..To obtain population-based estimates of emergency department (ED) visits by long-term care (LTC) residents...
Recent health care transitions and emergency department use by chronic long term care residents: a population-based cohort studyAndrea Gruneir
Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada
J Am Med Dir Assoc 13:202-6. 2012..Two types of transitions were considered: admission into LTC and discharge from hospital...
Unplanned readmissions after hospital discharge among patients identified as being at high risk for readmission using a validated predictive algorithmAndrea Gruneir
Women s College Research Institute, University of Toronto, Canada
Open Med 5:e104-11. 2011..The purpose of this study was to describe medical patients identified using a recently published and validated algorithm (the LACE index) as being at high risk for readmission and to examine their actual hospital readmission rates...
Confounders and intermediaries in case-control study designs: a strategy for distinguishing between the two when measured using the same variableAndrea Gruneir
Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada
Pharmacoepidemiol Drug Saf 20:221-8. 2011....
Emergency department use by older adults: a literature review on trends, appropriateness, and consequences of unmet health care needsAndrea Gruneir
Women s College Hospital, Toronto, Ontario, Canada
Med Care Res Rev 68:131-55. 2011..Gaps in the research literature result in a limited understanding of the full scope of the issue and opportunities for practice and policy intervention...
Transitions in long-term care and potential implications for quality reporting in Ontario, CanadaAndrea Gruneir
Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada
J Am Med Dir Assoc 11:629-35. 2010..To describe the proportion of long-term care (LTC) residents excluded from quality measurement because of standard length of stay inclusion criteria and the extent to which this varies across facilities...
Cholinesterase inhibitors and adverse pulmonary events in older people with chronic obstructive pulmonary disease and concomitant dementia: a population-based, cohort studyAnne Stephenson
Women s College Research Institute, Women s College Hospital, Toronto, ON, Canada
Drugs Aging 29:213-23. 2012..Cholinesterase inhibitors (ChEIs) are a mainstay treatment for individuals with dementia. ChEIs may worsen airflow obstruction because of their pro-cholinergic properties...
Older men with dementia are at greater risk than women of serious events after initiating antipsychotic therapyPaula A Rochon
Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada
J Am Geriatr Soc 61:55-61. 2013..To understand how drug therapy differently affects older women and men...
Antipsychotic drugs and the risk of hyperglycemia in older adults without diabetes: a population-based observational studyLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Am J Geriatr Psychiatry 19:1026-33. 2011..To determine whether current antipsychotic use among older persons without diabetes is associated with a higher risk of hospital visits for hyperglycemia, as previous studies in this population have yielded conflicting results...
Use of clarithromycin and adverse cardiovascular events among older patients receiving donepezil: a population-based, nested case-control studyJanine R Hutson
Faculty of Medicine, University of Toronto, Toronto, ON, Canada
Drugs Aging 29:205-11. 2012..Donepezil is metabolized by the cytochrome P450 isozyme 3A4 (CYP3A4). Clarithromycin is a potent inhibitor of CYP3A4, and patients taking both of these drugs may be at increased risk of cardiac adverse events...
Characteristics of older adults hospitalized in acute psychiatric units in ontario: a population-based studyDallas P Seitz
Department of Psychiatry, Queen s University, Kingston, Ontario, Canada
Can J Psychiatry 57:554-63. 2012..Understanding the characteristics of older adults in APUs is necessary to determine the range of inpatient services required for this population...
Effects of cholinesterase inhibitors on postoperative outcomes of older adults with dementia undergoing hip fracture surgeryDallas P Seitz
Kunin Lunenfeld Applied Research Unit, Baycrest Center, Toronto, Ontario, Canada
Am J Geriatr Psychiatry 19:803-13. 2011..We evaluated the effects of ChEIs on the postoperative outcomes of older adults who underwent hip fracture surgery...
Serious events in older Ontario residents receiving bowel preparations for outpatient colonoscopy with various comorbidity profiles: a descriptive, population-based studyJoanne Man Wai Ho
University of Toronto, Toronto, Ontario, Canada
Can J Gastroenterol 26:436-40. 2012..Little is known about adverse events associated with these preparations, particularly in older patients or patients with medical comorbidities...
Dihydropyridine calcium channel blockers and the progression of parkinsonismConnie Marras
Division of Neurology, Toronto Western Hospital, and University of Toronto, Toronto, Ontario, Canada
Ann Neurol 71:362-9. 2012..A study was undertaken to test the association between dihydropyridine calcium channel blocker use and the time to important milestones of disease progression among patients with parkinsonism...
Antipsychotics and mortality in ParkinsonismConnie Marras
Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, ON, Canada
Am J Geriatr Psychiatry 20:149-58. 2012..The use of antipsychotic medications is associated with an increased risk of death in older adults with dementia. The risk of death in patients with preexisting parkinsonism who receive antipsychotic drugs is not known...
Antibiotic use in long-term care facilitiesNick Daneman
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
J Antimicrob Chemother 66:2856-63. 2011..Our goal was to examine the prevalence of antibiotic use among long-term care facility residents and the extent of variability across these institutions...
Association between tamoxifen treatment and diabetes: a population-based studyLorraine L Lipscombe
Women s College Hospital, Toronto, Canada
Cancer 118:2615-22. 2012..Tamoxifen may increase diabetes incidence through its estrogen-inhibiting effects. This study assessed whether tamoxifen treatment in older breast cancer survivors is associated with an increased risk of diabetes...
Antipsychotic drugs and hyperglycemia in older patients with diabetesLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Arch Intern Med 169:1282-9. 2009..Evidence suggests that there is an association between antipsychotic drugs and new-onset diabetes, but little is known about the risk of hyperglycemia among persons with preexisting diabetes...
Association between tamsulosin and serious ophthalmic adverse events in older men following cataract surgeryChaim M Bell
Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
JAMA 301:1991-6. 2009..No studies have documented whether use of tamsulosin or other alpha-blocker drug therapies affect the risk of serious postoperative adverse events...
Inhaled anticholinergic drug therapy and the risk of acute urinary retention in chronic obstructive pulmonary disease: a population-based studyAnne Stephenson
Department of Medicine, Keenan Research Centre, Li Ka Shing Knowledge Institute of St Michael s Hospital, Toronto, ON, Canada
Arch Intern Med 171:914-20. 2011..The systemic anticholinergic effects of IAC therapy have not been extensively studied. This study sought to determine the risk of acute urinary retention (AUR) in seniors with COPD using IACs...
Antidepressants for agitation and psychosis in dementiaDallas P Seitz
Department of Psychiatry, Queen s University, 752 King Street West, Kingston, Ontario, Canada, K7L 4X3
Cochrane Database Syst Rev 2:CD008191. 2011..Agitation and psychosis are common among older adults with dementia and are challenging to manage. At the present time, little is known about the efficacy and safety of antidepressant medications when used to treat these symptoms...
Temporal trends in general and age-specific fertility rates among women with schizophrenia (1996-2009): a population-based study in Ontario, CanadaSimone N Vigod
Women s College Hospital and Women s College Research Institute, 76 Grenville St, Toronto, Ontario, Canada M5S 1B2
Schizophr Res 139:169-75. 2012..Our objective was to analyze recent trends in general and age-specific fertility rates among women with schizophrenia in Ontario, Canada...
Investigator experiences with financial conflicts of interest in clinical trialsPaula A Rochon
Women s College Research Institute at Women s College Hospital, Toronto, Canada
Trials 12:9. 2011..We obtained information from investigators about adherence to practices that minimize the introduction of such bias in their clinical trials experience...
Nursing time devoted to medication administration in long-term care: clinical, safety, and resource implicationsMary S Thomson
Baycrest Centre, Toronto, Ontario, Canada
J Am Geriatr Soc 57:266-72. 2009..To quantify the time required for nurses to complete the medication administration process in long-term care (LTC)...
Cholinesterase inhibitor use in U.S. nursing homes: results from the national nursing home surveyDallas P Seitz
Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
J Am Geriatr Soc 57:2269-74. 2009..To determine the frequency of cholinesterase inhibitor (ChEI) use in nursing home (NH) residents with dementia and examine correlates of ChEI use in this population...
Relationship between state medicaid policies, nursing home racial composition, and the risk of hospitalization for black and white residentsAndrea Gruneir
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, ON M6A 2E1, Canada
Health Serv Res 43:869-81. 2008..To examine racial differences in the risk of hospitalization for nursing home (NH) residents...
