Research Topics
| Wee Shian ChanSummaryAffiliation: Women's College Hospital Country: Canada Publications
|
Detail Information
Publications
A red blood cell agglutination D-dimer test to exclude deep venous thrombosis in pregnancyWee Shian Chan
Women s College Hospital, Toronto, Ontario, Canada
Ann Intern Med 147:165-70. 2007..The D-dimer test is highly sensitive, and a negative result can obviate the need for further testing for DVT. This test has not been studied for DVT diagnosis in pregnancy because its specificity was deemed too poor...
Venous thromboembolism in pregnancyWee Shian Chan
University of Toronto, Women s College Hospital, Department of Medicine, Toronto, ON, M5S 1B2, Canada
Expert Rev Cardiovasc Ther 8:1731-40. 2010..With increased use of assisted reproductive techniques to achieve pregnancy, clinicians must also be vigilant to the development of venous thrombosis in early pregnancy, occurring in unusual sites such as the upper extremities...
Anatomic distribution of deep vein thrombosis in pregnancyWee Shian Chan
Department of Medicine, University of Toronto, Toronto, Ont
CMAJ 182:657-60. 2010..We undertook this study to determine the anatomic distribution of deep vein thrombosis of the lower extremity in symptomatic pregnant patients...
D-dimer testing in pregnant patients: towards determining the next 'level' in the diagnosis of deep vein thrombosisW S Chan
Department of Medicine, Women s College Hospital, Toronto, ON, USA
J Thromb Haemost 8:1004-11. 2010..We hypothesized that the specificity of sensitive D-dimer assays could be improved without compromising sensitivity by using higher D-dimer cut-off values...
Predicting deep venous thrombosis in pregnancy: out in "LEFt" field?Wee Shian Chan
Department of Medicine, Women s College Hospital, Toronto, Ontario, Canada
Ann Intern Med 151:85-92. 2009..Pretest probability assessment for DVT diagnosis has never been evaluated in pregnant women...
The "ART" of thromboembolism: a review of assisted reproductive technology and thromboembolic complicationsW S Chan
Department of Medicine and Obstetrics and Gynecology, Women s College Hospital and Sunnybrook Health Sciences Centre, 76, Grenville Street, Toronto, Ontario, Canada M5S 1B2
Thromb Res 121:713-26. 2008....
The 'ART' of thrombosis: a review of arterial and venous thrombosis in assisted reproductive technologyWee Shian Chan
Department of Medicine, Women s College Hospital, 76 Grenville Street, Toronto, Ontario M5S 1B2, Canada
Curr Opin Obstet Gynecol 21:207-18. 2009..One major complication of this intervention, ovarian hyperstimulation syndrome (OHSS), is associated with both arterial and venous thromboembolic complications...
Diagnosis of deep vein thrombosis and pulmonary embolism in pregnancyWee Shian Chan
Department of Medicine, Women s College Ambulatory Care Centre, Sunnybrook and Women s College Health Sciences Centre, 76, Grenville Street, Toronto, ON, Canada M5S 1B2
Thromb Res 107:85-91. 2002..Future research is urgently needed to validate the use of current approaches and perhaps define safer and more accurate strategies to reduce maternal morbidity from this disease...
Safety of withholding anticoagulation in pregnant women with suspected deep vein thrombosis following negative serial compression ultrasound and iliac vein imagingWee Shian Chan
Department of Medicine, McMaster University, Hamilton, Ont
CMAJ 185:E194-200. 2013..We evaluated the safety of withholding anticoagulation from pregnant women with suspected deep vein thrombosis following negative serial compression ultrasonography and iliac vein imaging...
Risk of stroke in women exposed to low-dose oral contraceptives: a critical evaluation of the evidenceWee Shian Chan
Departments of Medicine, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
Arch Intern Med 164:741-7. 2004....
Anticoagulation of pregnant women with mechanical heart valvesJeffrey S Ginsberg
Department of Medicine, McMaster University, Hamilton, Ontario, Canada
Arch Intern Med 163:694-8. 2003..We believe a consensus conference among experts in the field to identify key unresolved issues and a commitment by the FDA and industry to perform appropriate studies are now critical...
Maternal body mass index and the risk of preeclampsia: a systematic overviewTara E O'Brien
Division of Obstetrical Medicine, Department of Medicine, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
Epidemiology 14:368-74. 2003..We performed a systematic overview of the literature to determine the association between prepregnancy body mass index and the risk of preeclampsia...
A review of upper extremity deep vein thrombosis in pregnancy: unmasking the 'ART' behind the clotW S Chan
Women s College Ambulatory Care Centre, Sunnybrook and Women s Health Sciences Centre, Toronto, ON
J Thromb Haemost 4:1673-7. 2006..Increasingly, UEDVTs are being reported during pregnancy, particularly those achieved with the use of assisted reproductive techniques (ART), and in conjunction with ovarian hyperstimulation syndrome (OHSS)...
Common C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of venous thromboembolism: meta-analysis of 31 studiesJ G Ray
Department of Medicine, Women s College Campus, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ont, Canada
Pathophysiol Haemost Thromb 32:51-8. 2002..We conducted a meta-analysis of previously published studies to clarify the role of the MTHFR 677 TT homozygous genotype in association with VTE...
