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Genomes and GenesSpecies | Ilan WeinrebSummaryCountry: Canada Publications
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Publications
Factitial soft tissue pseudotumor due to injection of anabolic steroids: a report of 3 cases in 2 patientsIlan Weinreb
Department of Pathology, University Health Network, Toronto, Ontario, Canada M5G 2C4
Hum Pathol 41:452-5. 2010..Recognition of this possibility is important in avoiding incorrect diagnoses and unnecessary treatments...
Low grade glandular lesions of the sinonasal tract: a focused reviewIlan Weinreb
Department of Pathology, University Health Network, 200 Elizabeth Street, Toronto, ON, M5G 2C4, Canada
Head Neck Pathol 4:77-83. 2010..However, complicating this category are controversies surrounding their nature as reactive lesions versus neoplasms, the histologic and immunohistochemical overlap, and possible precursor relationships between some of them...
Intraductal carcinoma of salivary gland (so-called low-grade cribriform cystadenocarcinoma) arising in an intraparotid lymph nodeIlan Weinreb
Department of Pathology, University Health Network and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G 2C4, Canada
Head Neck Pathol 5:321-5. 2011..They showed negligible MIB-1 staining. This report describes, for the first time, an entirely intranodal location for a low-grade intraductal carcinoma (so-called low-grade cribriform cystadenocarcinoma)...
CD10 is expressed in most epithelioid hemangioendotheliomas: a potential diagnostic pitfallIlan Weinreb
Department of Pathology, University Health Network, and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada
Arch Pathol Lab Med 133:1965-8. 2009..We recently encountered an EHE with strong CD10 positivity mimicking renal cell carcinoma...
Nodular fasciitis of the head and neck region: a clinicopathologic description in a series of 30 casesIlan Weinreb
Department of Pathology, University of Toronto, Ontario, Canada
J Cutan Pathol 36:1168-73. 2009..Follow up demonstrated one recurrence (7.1%) higher than reported elsewhere in the body. These latter features may add to the challenge in diagnosing NF in these locations...
Expression patterns of Trk-A, Trk-B, GRP78, and p75NRT in olfactory neuroblastomaIlan Weinreb
Department of Pathology, University Health Network, Toronto, Ontario, Canada
Hum Pathol 40:1330-5. 2009..None of these markers definitively correlated with patient outcome. Neurotrophin receptors do not appear to have a prognostic role; however, Trk's may play an oncogenic role in olfactory neuroblastoma...
Oncocytic mucoepidermoid carcinoma: clinicopathologic description in a series of 12 casesIlan Weinreb
Department of Pathology, University Health Network, University of Toronto, Toronto, Ontario, Canada
Am J Surg Pathol 33:409-16. 2009..Three cases showed skin or bone invasion. None had lymph node/distant metastases. In summary, OMEC behaves as a low-grade tumor, and is diffusely positive for p63, which may aid in its differential diagnosis...
Primary extraskeletal Ewing family tumor with complex epithelial differentiation: a unique case arising in the lateral neck presenting with Horner syndromeIlan Weinreb
Department of Pathology, University Health Network, Toronto, Ontario, Canada
Am J Surg Pathol 32:1742-8. 2008..It is also the first EFT with complex epithelial differentiation arising outside the extremities and with diffuse expression of high molecular weight keratin and p63...
Ductal adenomas of salivary gland showing features of striated duct differentiation ('striated duct adenoma'): a report of six casesIlan Weinreb
Department of Pathology, University Health Network, University of Toronto, Toronto, ON, Canada
Histopathology 57:707-15. 2010..To describe a salivary adenoma composed largely of unilayered ducts resembling striated ducts, and to differentiate it from similar adenomas, including canalicular and intercalated duct adenoma...
Mucinous, gland predominant synovial sarcoma of a large peripheral nerve: a rare case closely mimicking metastatic mucinous carcinomaI Weinreb
Department of Pathology, University Health Network, Toronto, Ontario, Canada
J Clin Pathol 61:672-6. 2008..Mucinous, gland predominant synovial sarcoma must be recognised to avoid misdiagnosis of metastatic carcinoma or a glandular malignant peripheral nerve sheath tumour when occurring in a peripheral nerve...
Pleomorphic angiomatoid fibrous histiocytoma: a case confirmed by fluorescence in situ hybridization analysis for EWSR1 rearrangementIlan Weinreb
Department of Pathology and Department of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario, Canada
J Cutan Pathol 35:855-60. 2008..Pleomorphic AFH should be included in the differential diagnosis of atypical mesenchymal tumors of skin and superficial subcutis and molecular testing may prove helpful in this regard...
Perivascular epithelioid cell neoplasms (PEComas): four malignant cases expanding the histopathological spectrum and a description of a unique findingIlan Weinreb
Department of Pathology, University Health Network, 200 Elizabeth Street, 11th Floor, Toronto, ON, M5G 2C4, Canada
Virchows Arch 450:463-70. 2007..These tumours may manifest largely as sarcomas appearing to be undifferentiated and should be considered in their differential diagnosis...
Cutaneous melanocytoneuroma: the first case of a distinctive intraneural tumor with dual nerve sheath and melanocytic differentiationIlan Weinreb
Department of Pathology, University Health Network, Toronto, Ontario, Canada
J Cutan Pathol 34:52-7. 2007..In conclusion, this unusual lesion represents an intraneural proliferation with melanocytic and nerve sheath cell differentiation, to which we have accorded the appellation, MCN...
Ectopic hamartomatous thymoma: a case demonstrating skin adnexal differentiation with positivity for epithelial membrane antigen, androgen receptors, and BRST-2 by immunohistochemistryIlan Weinreb
Department of Pathology, University Health Network, Toronto, Ontario, Canada
Hum Pathol 38:1092-5. 2007..The spindled component also expressed nuclear AR. AR positivity has not been described previously and may explain the occurrence primarily in men in postpubertal life...
Deintensification candidate subgroups in human papillomavirus-related oropharyngeal cancer according to minimal risk of distant metastasisBrian O'Sullivan
Room 5 624, Princess Margaret Hospital, 610 University Ave, Toronto, Ontario, Canada M5G 2M9
J Clin Oncol 31:543-50. 2013..02). CONCLUSION HPV-positive T1-3N0-2c patients have a low DM risk, but N2c patients from this group have a reduced DC when treated with RT alone and seem less suited for deintensification strategies that omit chemotherapy...
Intercalated duct lesions of salivary gland: a morphologic spectrum from hyperplasia to adenomaIlan Weinreb
Department of Pathology, University Health Network, University of Toronto, Toronto, Ontario M5G 2C4, Canada
Am J Surg Pathol 33:1322-9. 2009..There is an association with basal cell adenomas and EMC, which lends credence to their role as a putative precursor lesion...
A unique biphasic variant of cutaneous fibrous histiocytoma with a storiform pattern and intralesional pigmented melanocytes: "storiform melano-fibrous histiocytoma"Vidhya Nair
Department of Pathology, University Health Network, Toronto General Hospital, 200 Elizabeth Street, 11th Floor, Eaton Wing, Room 312, Toronto, M5G 2C4, Ontario, Canada
Eur J Dermatol 18:332-6. 2008..This case raises a nosological debate given the histological, immunophenotypic and cytogenetic findings...
Ewing's family of tumors of the sinonasal tract and maxillary boneSara Hafezi
Department of Pathology, University Health Network, Toronto, ON, Canada
Head Neck Pathol 5:8-16. 2011..Interestingly, however, an analysis of the literature suggests a better prognosis for sinonasal EFT than EFT overall...
Natural course of distant metastases following radiotherapy or chemoradiotherapy in HPV-related oropharyngeal cancerShao Hui Huang
Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Canada
Oral Oncol 49:79-85. 2013..To describe the natural course of distant metastases (DMs) following radiotherapy (RT) or chemoradiotherapy (CRT) in HPV(+) oropharyngeal carcinoma (OPC)...
Outcomes of HPV-related oropharyngeal cancer patients treated by radiotherapy alone using altered fractionationBrian O'Sullivan
Department of Radiation Oncology, Princess Margaret Hospital, Toronto, Canada
Radiother Oncol 103:49-56. 2012..To report outcome of HPV-related [HPV(+)] oropharyngeal cancer (OPC) managed predominantly by altered-fractionation radiotherapy-alone (RT-alone)...
Seromucinous hamartomas: a clinicopathological study of a sinonasal glandular lesion lacking myoepithelial cellsIlan Weinreb
Department of Pathology, University Health Network, University of Toronto, Toronto, ON, Canada
Histopathology 54:205-13. 2009..To describe seven cases of sinonasal seromucinous hamartoma...
Epithelial proliferation in small ducts of salivary cystadenoma resembling atypical ductal hyperplasia of breastLisa Fahim
Department of Pathology, University Health Network, 200 Elizabeth Street, Toronto, Ontario, Canada
Head Neck Pathol 2:213-7. 2008..Cystadenomas join the list of salivary gland lesions with microscopic similarities to primary lesions of the breast...
Calretinin staining facilitates differentiation of olfactory neuroblastoma from other small round blue cell tumors in the sinonasal tractJill C Wooff
Department of Pathology, Capital District Health Authority, Dalhousie University, Halifax, NS, USA
Am J Surg Pathol 35:1786-93. 2011..The purpose of this study is to determine the usefulness of calretinin and p63 as an aid to distinguish ONB from other sinonasal SRBCTs...
Epithelial-myoepithelial carcinoma with high grade transformationParomita Roy
Department of Pathology, University Health Network, Toronto, Ontario, Canada
Am J Surg Pathol 34:1258-65. 2010..We report these 3 such cases, review the literature and propose that these lesions be regarded as "EMC with high-grade transformation."..
Potentially Prognostic miRNAs in HPV-Associated Oropharyngeal CarcinomaAngela B Y Hui
Authors Affiliations Ontario Cancer Institute, University Health Network Division of Biostatistics, Division of Surgical Oncology, Division of Medical Oncology, and Department of Radiation Oncology, Princess Margaret Cancer Center Division of Signaling Biology, Ontario Cancer Institute Department of Pathology, University Health Network and Department of Radiation Oncology University of Toronto, Toronto, Ontario, Canada
Clin Cancer Res 19:2154-62. 2013..Seven FFPE specimens of histologically normal tonsils were used as controls...
Recurrent hyalinizing clear cell carcinoma of the base of tongue with high-grade transformation and EWSR1 gene rearrangement by FISHRongyu Jin
Department of Pathology, University Health Network, Toronto General Hospital Site, 200 Elizabeth Street, Toronto, ON, M5G 2C4, Canada
Head Neck Pathol 6:389-94. 2012..It also confirmed that the initial tumor was a HCCC with high-grade transformation...
Mammary analog secretory carcinoma of salivary gland origin with the ETV6 gene rearrangement by FISH: expanded morphologic and immunohistochemical spectrum of a recently described entityAshton Connor
Department of Pathology, University Health Network, University of Toronto, Toronto, ON, Canada
Am J Surg Pathol 36:27-34. 2012..These findings reinforce MASC as a unique low-grade salivary gland tumor entity with morphologic overlap with AciCC, MEC, and cystadenocarcinoma...
Olfactory neuroblastoma: a review and updateHala Faragalla
Department of Pathology, University Health Network, Toronto, ON, Canada
Adv Anat Pathol 16:322-31. 2009....
Atypical clinical behavior of p16-confirmed HPV-related oropharyngeal squamous cell carcinoma treated with radical radiotherapyShao Hui Huang
Department of Radiation Oncology, Princess Margaret Hospital University of Toronto, Toronto, Ontario, Canada
Int J Radiat Oncol Biol Phys 82:276-83. 2012..To report atypical clinical behavior observed in human papillomavirus (HPV)-related oropharyngeal carcinoma (OPC) treated with radiotherapy...
Low-grade intraductal carcinoma of salivary gland: report of 3 cases with marked apocrine differentiationIlan Weinreb
Department of Pathology, University Health Network, University of Toronto, Toronto, Ontario, Canada
Am J Surg Pathol 30:1014-21. 2006....
Equivocal p16 immunostaining in squamous cell carcinoma of the head and neck: staining patterns are suggestive of HPV statusZhongchuan Will Chen
Department of Laboratory Medicine and Pathobiology, University Health Network, University of Toronto, Toronto, ON, Canada
Head Neck Pathol 6:422-9. 2012..The HPV-positive cases determined by staining pattern were also associated with a higher percentage of stained tumor cells...
CD30 and Epstein-Barr virus RNA expression in sclerosing angiomatoid nodular transformation of spleenIlan Weinreb
Department of Pathology, University Health Network, 200 Elizabeth Street, 11th Floor, Toronto, Ontario M5G 2C4, Canada
Virchows Arch 451:73-9. 2007..In conclusion, SANT shows upregulation of CD30 with respect to normal spleen. The presence of EBV in the stromal cells of a case supports the notion that a subset of SANT may be related to IPT...
A spectrum of basaloid morphology in a subset of EBV-associated "lymphoepithelial carcinomas" of major salivary glandsJeppe Friborg
Department of Radiation Oncology, University Health Network, Toronto, ON, Canada
Head Neck Pathol 6:445-50. 2012..A basaloid variant of LEC in major salivary gland should be recognized, especially in highly prone populations, to avoid misdiagnosis of other more common salivary tumors...
microRNA evaluation of unknown primary lesions in the head and neckEmma V Barker
Department of Applied Molecular Oncology, Princess Margaret Hospital, Ontario Cancer Institute and University Health Network, Toronto, Ontario M5G 2M9, Canada
Mol Cancer 8:127. 2009..This may be clinically relevant to predict the primary site of origin of metastatic disease, when the primary site remains obscure...
Non-small cell neuroendocrine carcinoma of the sinonasal tract and nasopharynx. Report of 2 cases and review of the literatureIlan Weinreb
Department of Pathology, University Health Network, 200 Elizabeth Street, Toronto, Ontario, Canada
Head Neck Pathol 1:21-6. 2007..More studies are needed to better define the histopathologic spectrum of these lesions and to develop a clinically relevant classification...
Plexiform intraneural granular cell tumour of a digital cutaneous sensory nerveI Weinreb
Department of Pathology, University Health Network and University of Toronto, Toronto, Ontario, Canada
J Clin Pathol 60:725-6. 2007
