Bérubé C, Borgia A, Voyer N. A novel route towards cycle-tail peptides using oxime resin: teaching an old dog a new trick. Org Biomol Chem. 2018;16:9117-9123 pubmed publisher
..Also, as side-products of the synthesis, large C2-symmetric 38-member cyclic peptides ring bearing two endocyclic lysine side-chains were isolated, constituting a novel cyclic peptide scaffold. ..
Carpentier C, Barbeau X, Azelmat J, Vaillancourt K, Grenier D, Lagüe P, et al
. Lobaric acid and pseudodepsidones inhibit NF-κB signaling pathway by activation of PPAR-γ. Bioorg Med Chem. 2018;26:5845-5851 pubmed publisher
..These findings suggest that lobaric acid and pseudodepsidones reduce the expression of pro-inflammatory cytokines by blocking the NF-κB pathway via the activation of PPAR-γ. ..
Cardinal S, Azelmat J, Grenier D, Voyer N. Anti-inflammatory properties of quebecol and its derivatives. Bioorg Med Chem Lett. 2016;26:440-444 pubmed publisher
..Comparing the results obtained for all tested compounds allowed the identification of the main moiety responsible for the anti-inflammatory activity of quebecol. ..
Cardinal S, Paquet Côté P, Azelmat J, Bouchard C, Grenier D, Voyer N. Synthesis and anti-inflammatory activity of isoquebecol. Bioorg Med Chem. 2017;25:2043-2056 pubmed publisher
..Comparison between the three series of compounds led to establishing new SARs concerning the aryl ring substitution pattern on the triarylpropanol scaffold and substructure functionalization. ..
BÃ©rubÃ© C, Barbeau X, LagÃ¼e P, Voyer N. Revisiting the JuliÃ¡-Colonna enantioselective epoxidation: supramolecular catalysis in water. Chem Commun (Camb). 2017;53:5099-5102 pubmed publisher