Patrick Vigneault

Summary

Country: Canada

Publications

  1. doi Iloperidone (Fanapt®), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration
    Patrick Vigneault
    Faculte de Pharmacie, Universite Laval, Quebec QC, Canada
    Pharmacol Res 66:60-5. 2012
  2. doi Galantamine (Reminyl) delays cardiac ventricular repolarization and prolongs the QT interval by blocking the HERG current
    Patrick Vigneault
    Faculte de Pharmacie, Universite Laval, Pavillon Ferdinand Vandry, 1050 avenue de la Medecine, Quebec QC, Canada G1V 0A6
    Eur J Pharmacol 681:68-74. 2012
  3. doi QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile
    Bertrand Caillier
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec QC, Canada
    Fundam Clin Pharmacol 26:599-608. 2012
  4. doi Prolongation of cardiac ventricular repolarization under paliperidone: how and how much?
    Patrick Vigneault
    Faculte de Pharmacie, Universite Laval, Quebec, Canada
    J Cardiovasc Pharmacol 57:690-5. 2011

Collaborators

  • Pascal Daleau
  • Yves De Koninck
  • Bertrand Caillier
  • Dany Patoine
  • Sylvie Pilote
  • Raymond Hreiche
  • Chantale Simard
  • Jacques Turgeon
  • Verlaine Ménard-Desrosiers
  • Annie Castonguay
  • Benoit Drolet

Detail Information

Publications4

  1. doi Iloperidone (Fanapt®), a novel atypical antipsychotic, is a potent HERG blocker and delays cardiac ventricular repolarization at clinically relevant concentration
    Patrick Vigneault
    Faculte de Pharmacie, Universite Laval, Quebec QC, Canada
    Pharmacol Res 66:60-5. 2012
    ..Patients are at increased risk of cardiac proarrhythmia during iloperidone treatment, as this drug possesses significant cardiac repolarization-delaying properties at clinically relevant concentration...
  2. doi Galantamine (Reminyl) delays cardiac ventricular repolarization and prolongs the QT interval by blocking the HERG current
    Patrick Vigneault
    Faculte de Pharmacie, Universite Laval, Pavillon Ferdinand Vandry, 1050 avenue de la Medecine, Quebec QC, Canada G1V 0A6
    Eur J Pharmacol 681:68-74. 2012
    ..Galantamine is a weak HERG blocker. This contributes to its mild QT-prolonging effect. Patients could be at risk of cardiac proarrhythmia during drug overdosage or interactions involving cytochrome 2D6 drug-metabolizing enzyme...
  3. doi QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile
    Bertrand Caillier
    Centre de Recherche de l Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec QC, Canada
    Fundam Clin Pharmacol 26:599-608. 2012
    ..Unlike class I anti-arrhythmics, bupropion causes cardiac conduction disturbances by reducing cardiac intercellular coupling...
  4. doi Prolongation of cardiac ventricular repolarization under paliperidone: how and how much?
    Patrick Vigneault
    Faculte de Pharmacie, Universite Laval, Quebec, Canada
    J Cardiovasc Pharmacol 57:690-5. 2011
    ..Paliperidone (9-hydroxyrisperidone) is a second-generation antipsychotic. As observed with risperidone, QT interval prolongation was reported with paliperidone...