Research Topics
| K K ZakzanisSummaryAffiliation: University of Toronto Country: Canada Publications
| Collaborators
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Detail Information
Publications
Neurocognitive deficits in cocaine users: a quantitative review of the evidenceDiana Jovanovski
University of Toronto, Life Sciences, Toronto, Ontario, Canada
J Clin Exp Neuropsychol 27:189-204. 2005..Methodological limitations of the empirical studies included in the analysis are discussed...- Memory impairment in now abstinent MDMA users and continued users: a longitudinal follow-upKonstantine K Zakzanis
Department of Life Sciences, University of Toronto at Scarborough, Toronto, Ontario, Canada
Neurology 66:740-1. 2006..Current users demonstrated further declines in memory ability; former users improved on several memory measures or remained static in performance... - Assessing the relationship between insight and everyday executive deficits in schizophrenia: a pilot studyDiana Jovanovski
Department of Life Sciences Psychology, University of Toronto at Scarborough, 1265 Military Trail, Toronto, ON, Canada M1C 1A4
Psychiatry Res 151:47-54. 2007.... 
The predictive utility of neuropsychological symptom validity testing as it relates to psychological presentationKonstantine K Zakzanis
Department of Psychology, University of Toronto Scarborough, Toronto, Ontario, Canada
Appl Neuropsychol Adult 19:98-107. 2012....- A shrinking span of temporal continuity in dementia of the Alzheimer's typeKonstantine K Zakzanis
Division of Life Sciences, University of Toronto, Ontario, Canada
Neuropsychiatry Neuropsychol Behav Neurol 15:143-7. 2002..To examine the integrity of memory function in terms of temporal continuity in a way that would engage a patient in everyday behavior, such as informal conversation, but still allow memory function to be quantified... - Executive function in abstinent MDMA ('ecstasy') usersK K Zakzanis
Division of Life Sciences, University of Toronto, Toronto, Canada
Med Sci Monit 7:1292-8. 2001..This study sought to determine whether individuals with a history of MDMA use showed evidence of executive dysfunction... - A meta-analysis of structural and functional brain imaging in dementia of the Alzheimer's type: a neuroimaging profileKonstantine K Zakzanis
Division of Life Sciences, University of Toronto, Toronto, Ontario, Canada
Neuropsychol Rev 13:1-18. 2003..This signature is consistent with the clinical phenomenology of Alzheimer's dementia and should aid in the positive identification of AD... - Neuropsychological differentiation of late-onset schizophrenia and dementia of the Alzheimer's typeKonstantine K Zakzanis
Division of Life Sciences, University of Toronto at Scarborough, Toronto, Ontario, Canada
Appl Neuropsychol 10:105-14. 2003..This investigation was preliminary in nature, and should aid in the development of a definitive differential profile... - The neuropsychology of ecstasy (MDMA) use: a quantitative reviewKonstantine K Zakzanis
Department of Psychology, University of Toronto at Scarborough, Toronto, Ontario, Canada
Hum Psychopharmacol 22:427-35. 2007..Implications and limitations of these findings are discussed... - Age and dementia related differences in spatial navigation within an immersive virtual environmentKonstantine K Zakzanis
Department of Psychology, University of Toronto at Scarborough College, Toronto, Ontario, Canada
Med Sci Monit 15:CR140-50. 2009..The purpose of this study was to examine age- and Alzheimer's disease-related differences in route learning and memory using VR... - Quantitative evidence for distinct cognitive impairment in anorexia nervosa and bulimia nervosaKonstantine K Zakzanis
Department of Psychology, University of Toronto Scarborough, Toronto, Canada
J Neuropsychol 4:89-106. 2010..Implications of these findings with respects to future research are discussed... - Component analysis of verbal fluency in patients with mild traumatic brain injuryKonstantine K Zakzanis
Department of Psychology, University of Toronto Scarborough, Toronto, ON, Canada
J Clin Exp Neuropsychol 33:785-92. 2011..Given the small sample sizes employed in our study, however, future studies are needed to determine whether component measures of verbal fluency have discriminative ability... - Neurocognitive variability in high-functioning individuals: implications for the practice of clinical neuropsychologyKonstantine K Zakzanis
Department of Psychology, University of Toronto Scarborough College, 1265 Military Trail, Toronto, Ontario, M1C 1A4, Canada
Psychol Rep 108:290-300. 2011.... - Base rates of post-concussive symptoms in a nonconcussed multicultural sampleKonstantine K Zakzanis
Department of Psychology, University of Toronto Scarborough, Toronto, Ontario, Canada
Arch Clin Neuropsychol 26:461-5. 2011..Our results underscore the importance of considering the influence of culture and language, in conjunction with a growing list of factors that can influence, maintain, and/or mimic persistent PCS... - Attentional processes in abstinent methylenedioxymethamphetamine (ecstasy) usersKonstantine K Zakzanis
Division of Life Sciences, University of Toronto, Canada
Appl Neuropsychol 9:84-91. 2002..This finding brings to light the important relationship between poor attentional processes and drug-taking behaviors and their reciprocal relationship... - Prediction of longitudinal functional outcomes in schizophrenia: the impact of baseline motivational deficitsG Foussias
Centre for Addiction and Mental Health, and Department of Psychiatry, University of Toronto, 250 College St, Toronto, Ontario, Canada M5T 1R8
Schizophr Res 132:24-7. 2011..These findings further suggest a fundamental role for motivational deficits in predicting functional outcomes in schizophrenia... - Neuropsychological correlates of positive vs. negative schizophrenic symptomatologyK K Zakzanis
York University, Department of Psychology, Ontario, Canada
Schizophr Res 29:227-33. 1998..negative dichotomy. The results further the hypothesis that schizophrenia is not a single disease entity... - Neurocognitive deficit in schizophrenia: a quantitative review of the evidenceR W Heinrichs
Department of Psychology, York University, Toronto, Ontario, Canada
Neuropsychology 12:426-45. 1998..The results indicate that schizophrenia is characterized by a broadly based cognitive impairment, with varying degrees of deficit in all ability domains measured by standard clinical tests... - The subcortical dementia of Huntington's diseaseK K Zakzanis
Department of Psychology, York University, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
J Clin Exp Neuropsychol 20:565-78. 1998..A rank-order list of specific neuropsychological tasks and test variables in order of sensitivity to HD is also provided to aid in the interpretation of the quantitative results... - Visually navigating a virtual world with real-world impairments: a study of visually and spatially guided performance in individuals with mild cognitive impairmentsWilliam J Tippett
L C Campbell Cognitive Neurology Research Unit, Ontario, Canada
J Clin Exp Neuropsychol 31:447-54. 2009.... - Structural and functional meta-analytic evidence for fronto-subcortical system deficit in progressive supranuclear palsyK K Zakzanis
York University, Toronto, Canada
Brain Cogn 38:283-96. 1998..We conclude that although neuropsychological measures may be most sensitive to deficits in PSP, they are also less specific and valid indicators of fronto-subcortical brain system integrity... - Schizophrenia and the frontal brain: a quantitative reviewK K Zakzanis
Department of Psychology, University of Toronto, Ontario, Canada
J Int Neuropsychol Soc 5:556-66. 1999..Overall, the findings are hard to incorporate within single disease models that propose major involvement of the frontal system, at least at the degree of resolution obtained with current imaging technology... - Motivational deficits as the central link to functioning in schizophrenia: a pilot studyG Foussias
Department of Psychiatry, University of Toronto, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Schizophr Res 115:333-7. 2009..This suggests that motivational deficits are the central link between negative symptoms and functional impairment in schizophrenia... - The impact of treatment on HPA axis activity in unipolar major depressionMartha S McKay
Department of Psychology, University of Toronto, Sidney Smith Hall, Canada M5S 3G3
J Psychiatr Res 44:183-92. 2010.... - Convergent validity and sex differences in healthy elderly adults for performance on 3D virtual reality navigation learning and 2D hidden maze tasksWilliam J Tippett
Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Cyberpsychol Behav 12:169-74. 2009..Results suggest reasonable convergent validity across the VE task, GMLT, and selected neuropsychological tests for assessment of spatial memory... - A comparison between a researcher-rated and a self-report method of insight assessment in chronic schizophrenia revisited: a replication study using the SUMD and SAIQDiana Jovanovski
Department of Life Sciences Psychology, University of Toronto at Scarborough, Ontario, Canada
J Nerv Ment Dis 195:165-9. 2007..The reliability of insight scales may be substantially improved if a self-report insight scale is administered prior to a researcher-rated scale... - Quantitative evidence for neuroanatomic and neuropsychological markers in dementia of the Alzheimer's typeK K Zakzanis
York University, Department of Psychology, Toronto, Canada
J Clin Exp Neuropsychol 20:259-69. 1998.... - Memory impairment in abstinent MDMA ("Ecstasy") users: a longitudinal investigationK K Zakzanis
Division of Life Sciences, University of Toronto, Ontario, Canada
Neurology 56:966-9. 2001..Subjects were abstinent for 2 weeks on initial and 1-year testing. Continued use of MDMA was associated with progressive decline in terms of immediate and delayed recall... - A neuropsychological comparison of demented and nondemented patients with Parkinson's diseaseK K Zakzanis
Department of Psychology, York University, Toronto, Canada
Appl Neuropsychol 6:129-46. 1999..That is, as the duration of the disease endures, it appears that performance on tasks of delayed recall deteriorates first, followed by performance on measures of manual dexterity, cognitive flexibility, and abstraction... - The neuropsychological signature of primary progressive aphasiaK K Zakzanis
Department of Psychology, University of Toronto, Toronto, Canada
Brain Lang 70:70-85. 1999.... - Component analysis of verbal fluency in patients with schizophreniaK K Zakzanis
Division of Life Sciences Psychology, University of Toronto at Scarborough, Ontario, Canada
Neuropsychiatry Neuropsychol Behav Neurol 13:239-45. 2000..Clustering and-switching components of phonemic fluency performance were compared in patients with schizophrenia and healthy normal controls... - A platform for combining virtual reality experiments with functional magnetic resonance imagingRichard Mraz
Imaging Research, Sunnybrook and Women's College Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5
Cyberpsychol Behav 6:359-68. 2003..Future research directions for combined use of VR and fMRI are also discussed... - Utilizing virtual reality to improve the ecological validity of clinical neuropsychology: an FMRI case study elucidating the neural basis of planning by comparing the Tower of London with a three-dimensional navigation taskZachariah Campbell
Department of Psychology, University of Toronto Scarborough, Toronto, Canada
Appl Neuropsychol 16:295-306. 2009..This finding may extend to all domains of inquiry in neuropsychological research and assessment when deductive conclusions are formulated on the results of neuropsychological test measures that could be considered contrived in nature... - Dopamine D2 densities and the schizophrenic brainK K Zakzanis
Department of Psychology, York University, Toronto, Ont, Canada
Schizophr Res 32:201-6. 1998..Based on the findings, it is argued that D2 density receptor increases in patients with schizophrenia, although a reliable finding in many patients (i.e., approximately 70%), is not a specific or consistent marker for schizophrenia... - A comparison between an interview and a self-report method of insight assessment in chronic schizophreniaDonald A Young
Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Schizophr Res 63:103-9. 2003.... - Donepezil in a chronic drug user--a potential treatment?Diana Jovanovski
Department of Life Sciences, University of Toronto, Ontario, Canada
Hum Psychopharmacol 18:561-4. 2003.... - Brain is related to behavior (p<.05)K K Zakzanis
Department of Psychology, York University, Toronto, Ontario, Canada
J Clin Exp Neuropsychol 20:419-27. 1998..It is recommended on the basis of this review that the consumer of neuropsychological reports will be better served if due consideration is given to the magnitude of effect in brain-behavior statistical analyses... - A comparison of donepezil and galantamine in the treatment of cognitive symptoms of Alzheimer's disease: a meta-analysisRobin D J Harry
University of Toronto at Scarborough, Toronto, Canada
Hum Psychopharmacol 20:183-7. 2005..However, this result does not necessarily diminish the practical value of the drug. It was also found that galantamine was no better than donepezil at treating cognitive decline in AD... - An fMRI study of the Trail Making TestKonstantine K Zakzanis
Department of Life Sciences, University of Toronto, Toronto, ON, Canada
Neuropsychologia 43:1878-86. 2005..However, other activity was also observed (left middle and superior temporal gyrus) reinforcing that the brain-behavior correlations for the TMT are multifaceted and not restricted to the frontal lobe...