K K Zakzanis

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Neurocognitive deficits in cocaine users: a quantitative review of the evidence
    Diana Jovanovski
    University of Toronto, Life Sciences, Toronto, Ontario, Canada
    J Clin Exp Neuropsychol 27:189-204. 2005
  2. ncbi request reprint Memory impairment in now abstinent MDMA users and continued users: a longitudinal follow-up
    Konstantine K Zakzanis
    Department of Life Sciences, University of Toronto at Scarborough, Toronto, Ontario, Canada
    Neurology 66:740-1. 2006
  3. ncbi request reprint Assessing the relationship between insight and everyday executive deficits in schizophrenia: a pilot study
    Diana Jovanovski
    Department of Life Sciences Psychology, University of Toronto at Scarborough, 1265 Military Trail, Toronto, ON, Canada M1C 1A4
    Psychiatry Res 151:47-54. 2007
  4. doi request reprint Component analysis of verbal fluency scores in severe traumatic brain injury
    Konstantine K Zakzanis
    Department of Psychology, University of Toronto Scarborough, Toronto, Ontario, Canada
    Brain Inj 27:903-8. 2013
  5. doi request reprint The predictive utility of neuropsychological symptom validity testing as it relates to psychological presentation
    Konstantine K Zakzanis
    Department of Psychology, University of Toronto Scarborough, Toronto, Ontario, Canada
    Appl Neuropsychol Adult 19:98-107. 2012
  6. ncbi request reprint Attentional processes in abstinent methylenedioxymethamphetamine (ecstasy) users
    Konstantine K Zakzanis
    Division of Life Sciences, University of Toronto, Canada
    Appl Neuropsychol 9:84-91. 2002
  7. ncbi request reprint A shrinking span of temporal continuity in dementia of the Alzheimer's type
    Konstantine K Zakzanis
    Division of Life Sciences, University of Toronto, Ontario, Canada
    Neuropsychiatry Neuropsychol Behav Neurol 15:143-7. 2002
  8. ncbi request reprint Executive function in abstinent MDMA ('ecstasy') users
    K K Zakzanis
    Division of Life Sciences, University of Toronto, Toronto, Canada
    Med Sci Monit 7:1292-8. 2001
  9. ncbi request reprint Neuropsychological differentiation of late-onset schizophrenia and dementia of the Alzheimer's type
    Konstantine K Zakzanis
    Division of Life Sciences, University of Toronto at Scarborough, Toronto, Ontario, Canada
    Appl Neuropsychol 10:105-14. 2003
  10. ncbi request reprint The neuropsychology of ecstasy (MDMA) use: a quantitative review
    Konstantine K Zakzanis
    Department of Psychology, University of Toronto at Scarborough, Toronto, Ontario, Canada
    Hum Psychopharmacol 22:427-35. 2007

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Neurocognitive deficits in cocaine users: a quantitative review of the evidence
    Diana Jovanovski
    University of Toronto, Life Sciences, Toronto, Ontario, Canada
    J Clin Exp Neuropsychol 27:189-204. 2005
    ..Methodological limitations of the empirical studies included in the analysis are discussed...
  2. ncbi request reprint Memory impairment in now abstinent MDMA users and continued users: a longitudinal follow-up
    Konstantine K Zakzanis
    Department of Life Sciences, University of Toronto at Scarborough, Toronto, Ontario, Canada
    Neurology 66:740-1. 2006
    ..Current users demonstrated further declines in memory ability; former users improved on several memory measures or remained static in performance...
  3. ncbi request reprint Assessing the relationship between insight and everyday executive deficits in schizophrenia: a pilot study
    Diana Jovanovski
    Department of Life Sciences Psychology, University of Toronto at Scarborough, 1265 Military Trail, Toronto, ON, Canada M1C 1A4
    Psychiatry Res 151:47-54. 2007
    ....
  4. doi request reprint Component analysis of verbal fluency scores in severe traumatic brain injury
    Konstantine K Zakzanis
    Department of Psychology, University of Toronto Scarborough, Toronto, Ontario, Canada
    Brain Inj 27:903-8. 2013
    ..This study set out to examine the sensitivity of verbal fluency component scores in severe traumatic brain injury (TBI)...
  5. doi request reprint The predictive utility of neuropsychological symptom validity testing as it relates to psychological presentation
    Konstantine K Zakzanis
    Department of Psychology, University of Toronto Scarborough, Toronto, Ontario, Canada
    Appl Neuropsychol Adult 19:98-107. 2012
    ....
  6. ncbi request reprint Attentional processes in abstinent methylenedioxymethamphetamine (ecstasy) users
    Konstantine K Zakzanis
    Division of Life Sciences, University of Toronto, Canada
    Appl Neuropsychol 9:84-91. 2002
    ..This finding brings to light the important relationship between poor attentional processes and drug-taking behaviors and their reciprocal relationship...
  7. ncbi request reprint A shrinking span of temporal continuity in dementia of the Alzheimer's type
    Konstantine K Zakzanis
    Division of Life Sciences, University of Toronto, Ontario, Canada
    Neuropsychiatry Neuropsychol Behav Neurol 15:143-7. 2002
    ..To examine the integrity of memory function in terms of temporal continuity in a way that would engage a patient in everyday behavior, such as informal conversation, but still allow memory function to be quantified...
  8. ncbi request reprint Executive function in abstinent MDMA ('ecstasy') users
    K K Zakzanis
    Division of Life Sciences, University of Toronto, Toronto, Canada
    Med Sci Monit 7:1292-8. 2001
    ..This study sought to determine whether individuals with a history of MDMA use showed evidence of executive dysfunction...
  9. ncbi request reprint Neuropsychological differentiation of late-onset schizophrenia and dementia of the Alzheimer's type
    Konstantine K Zakzanis
    Division of Life Sciences, University of Toronto at Scarborough, Toronto, Ontario, Canada
    Appl Neuropsychol 10:105-14. 2003
    ..This investigation was preliminary in nature, and should aid in the development of a definitive differential profile...
  10. ncbi request reprint The neuropsychology of ecstasy (MDMA) use: a quantitative review
    Konstantine K Zakzanis
    Department of Psychology, University of Toronto at Scarborough, Toronto, Ontario, Canada
    Hum Psychopharmacol 22:427-35. 2007
    ..Implications and limitations of these findings are discussed...
  11. ncbi request reprint Age and dementia related differences in spatial navigation within an immersive virtual environment
    Konstantine K Zakzanis
    Department of Psychology, University of Toronto at Scarborough College, Toronto, Ontario, Canada
    Med Sci Monit 15:CR140-50. 2009
    ..The purpose of this study was to examine age- and Alzheimer's disease-related differences in route learning and memory using VR...
  12. doi request reprint Quantitative evidence for distinct cognitive impairment in anorexia nervosa and bulimia nervosa
    Konstantine K Zakzanis
    Department of Psychology, University of Toronto Scarborough, Toronto, Canada
    J Neuropsychol 4:89-106. 2010
    ..Implications of these findings with respects to future research are discussed...
  13. doi request reprint Component analysis of verbal fluency in patients with mild traumatic brain injury
    Konstantine K Zakzanis
    Department of Psychology, University of Toronto Scarborough, Toronto, ON, Canada
    J Clin Exp Neuropsychol 33:785-92. 2011
    ..Given the small sample sizes employed in our study, however, future studies are needed to determine whether component measures of verbal fluency have discriminative ability...
  14. ncbi request reprint Neurocognitive variability in high-functioning individuals: implications for the practice of clinical neuropsychology
    Konstantine K Zakzanis
    Department of Psychology, University of Toronto Scarborough College, 1265 Military Trail, Toronto, Ontario, M1C 1A4, Canada
    Psychol Rep 108:290-300. 2011
    ....
  15. doi request reprint Base rates of post-concussive symptoms in a nonconcussed multicultural sample
    Konstantine K Zakzanis
    Department of Psychology, University of Toronto Scarborough, Toronto, Ontario, Canada
    Arch Clin Neuropsychol 26:461-5. 2011
    ..Our results underscore the importance of considering the influence of culture and language, in conjunction with a growing list of factors that can influence, maintain, and/or mimic persistent PCS...
  16. ncbi request reprint A meta-analysis of structural and functional brain imaging in dementia of the Alzheimer's type: a neuroimaging profile
    Konstantine K Zakzanis
    Division of Life Sciences, University of Toronto, Toronto, Ontario, Canada
    Neuropsychol Rev 13:1-18. 2003
    ..This signature is consistent with the clinical phenomenology of Alzheimer's dementia and should aid in the positive identification of AD...
  17. doi request reprint Prediction of longitudinal functional outcomes in schizophrenia: the impact of baseline motivational deficits
    G Foussias
    Centre for Addiction and Mental Health, and Department of Psychiatry, University of Toronto, 250 College St, Toronto, Ontario, Canada M5T 1R8
    Schizophr Res 132:24-7. 2011
    ..These findings further suggest a fundamental role for motivational deficits in predicting functional outcomes in schizophrenia...
  18. ncbi request reprint Neuropsychological correlates of positive vs. negative schizophrenic symptomatology
    K K Zakzanis
    York University, Department of Psychology, Ontario, Canada
    Schizophr Res 29:227-33. 1998
    ..negative dichotomy. The results further the hypothesis that schizophrenia is not a single disease entity...
  19. ncbi request reprint Neurocognitive deficit in schizophrenia: a quantitative review of the evidence
    R W Heinrichs
    Department of Psychology, York University, Toronto, Ontario, Canada
    Neuropsychology 12:426-45. 1998
    ..The results indicate that schizophrenia is characterized by a broadly based cognitive impairment, with varying degrees of deficit in all ability domains measured by standard clinical tests...
  20. ncbi request reprint The subcortical dementia of Huntington's disease
    K K Zakzanis
    Department of Psychology, York University, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
    J Clin Exp Neuropsychol 20:565-78. 1998
    ..A rank-order list of specific neuropsychological tasks and test variables in order of sensitivity to HD is also provided to aid in the interpretation of the quantitative results...
  21. doi request reprint Visually navigating a virtual world with real-world impairments: a study of visually and spatially guided performance in individuals with mild cognitive impairments
    William J Tippett
    L C Campbell Cognitive Neurology Research Unit, Ontario, Canada
    J Clin Exp Neuropsychol 31:447-54. 2009
    ....
  22. doi request reprint Motivational deficits as the central link to functioning in schizophrenia: a pilot study
    G Foussias
    Department of Psychiatry, University of Toronto, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Schizophr Res 115:333-7. 2009
    ..This suggests that motivational deficits are the central link between negative symptoms and functional impairment in schizophrenia...
  23. ncbi request reprint Structural and functional meta-analytic evidence for fronto-subcortical system deficit in progressive supranuclear palsy
    K K Zakzanis
    York University, Toronto, Canada
    Brain Cogn 38:283-96. 1998
    ..We conclude that although neuropsychological measures may be most sensitive to deficits in PSP, they are also less specific and valid indicators of fronto-subcortical brain system integrity...
  24. ncbi request reprint A neuropsychological comparison of demented and nondemented patients with Parkinson's disease
    K K Zakzanis
    Department of Psychology, York University, Toronto, Canada
    Appl Neuropsychol 6:129-46. 1999
    ..That is, as the duration of the disease endures, it appears that performance on tasks of delayed recall deteriorates first, followed by performance on measures of manual dexterity, cognitive flexibility, and abstraction...
  25. ncbi request reprint Schizophrenia and the frontal brain: a quantitative review
    K K Zakzanis
    Department of Psychology, University of Toronto, Ontario, Canada
    J Int Neuropsychol Soc 5:556-66. 1999
    ..Overall, the findings are hard to incorporate within single disease models that propose major involvement of the frontal system, at least at the degree of resolution obtained with current imaging technology...
  26. ncbi request reprint A comparison between a researcher-rated and a self-report method of insight assessment in chronic schizophrenia revisited: a replication study using the SUMD and SAIQ
    Diana Jovanovski
    Department of Life Sciences Psychology, University of Toronto at Scarborough, Ontario, Canada
    J Nerv Ment Dis 195:165-9. 2007
    ..The reliability of insight scales may be substantially improved if a self-report insight scale is administered prior to a researcher-rated scale...
  27. doi request reprint The impact of treatment on HPA axis activity in unipolar major depression
    Martha S McKay
    Department of Psychology, University of Toronto, Sidney Smith Hall, Canada M5S 3G3
    J Psychiatr Res 44:183-92. 2010
    ....
  28. doi request reprint Convergent validity and sex differences in healthy elderly adults for performance on 3D virtual reality navigation learning and 2D hidden maze tasks
    William J Tippett
    Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Cyberpsychol Behav 12:169-74. 2009
    ..Results suggest reasonable convergent validity across the VE task, GMLT, and selected neuropsychological tests for assessment of spatial memory...
  29. ncbi request reprint Quantitative evidence for neuroanatomic and neuropsychological markers in dementia of the Alzheimer's type
    K K Zakzanis
    York University, Department of Psychology, Toronto, Canada
    J Clin Exp Neuropsychol 20:259-69. 1998
    ....
  30. ncbi request reprint Memory impairment in abstinent MDMA ("Ecstasy") users: a longitudinal investigation
    K K Zakzanis
    Division of Life Sciences, University of Toronto, Ontario, Canada
    Neurology 56:966-9. 2001
    ..Subjects were abstinent for 2 weeks on initial and 1-year testing. Continued use of MDMA was associated with progressive decline in terms of immediate and delayed recall...
  31. ncbi request reprint The neuropsychological signature of primary progressive aphasia
    K K Zakzanis
    Department of Psychology, University of Toronto, Toronto, Canada
    Brain Lang 70:70-85. 1999
    ....
  32. ncbi request reprint Component analysis of verbal fluency in patients with schizophrenia
    K K Zakzanis
    Division of Life Sciences Psychology, University of Toronto at Scarborough, Ontario, Canada
    Neuropsychiatry Neuropsychol Behav Neurol 13:239-45. 2000
    ..Clustering and-switching components of phonemic fluency performance were compared in patients with schizophrenia and healthy normal controls...
  33. doi request reprint Utilizing virtual reality to improve the ecological validity of clinical neuropsychology: an FMRI case study elucidating the neural basis of planning by comparing the Tower of London with a three-dimensional navigation task
    Zachariah Campbell
    Department of Psychology, University of Toronto Scarborough, Toronto, Canada
    Appl Neuropsychol 16:295-306. 2009
    ..This finding may extend to all domains of inquiry in neuropsychological research and assessment when deductive conclusions are formulated on the results of neuropsychological test measures that could be considered contrived in nature...
  34. ncbi request reprint A platform for combining virtual reality experiments with functional magnetic resonance imaging
    Richard Mraz
    Imaging Research, Sunnybrook and Women s College Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, Canada M4N 3M5
    Cyberpsychol Behav 6:359-68. 2003
    ..Future research directions for combined use of VR and fMRI are also discussed...
  35. ncbi request reprint Dopamine D2 densities and the schizophrenic brain
    K K Zakzanis
    Department of Psychology, York University, Toronto, Ont, Canada
    Schizophr Res 32:201-6. 1998
    ..Based on the findings, it is argued that D2 density receptor increases in patients with schizophrenia, although a reliable finding in many patients (i.e., approximately 70%), is not a specific or consistent marker for schizophrenia...
  36. ncbi request reprint A comparison between an interview and a self-report method of insight assessment in chronic schizophrenia
    Donald A Young
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Schizophr Res 63:103-9. 2003
    ....
  37. ncbi request reprint Donepezil in a chronic drug user--a potential treatment?
    Diana Jovanovski
    Department of Life Sciences, University of Toronto, Ontario, Canada
    Hum Psychopharmacol 18:561-4. 2003
    ....
  38. ncbi request reprint Brain is related to behavior (p<.05)
    K K Zakzanis
    Department of Psychology, York University, Toronto, Ontario, Canada
    J Clin Exp Neuropsychol 20:419-27. 1998
    ..It is recommended on the basis of this review that the consumer of neuropsychological reports will be better served if due consideration is given to the magnitude of effect in brain-behavior statistical analyses...
  39. ncbi request reprint A comparison of donepezil and galantamine in the treatment of cognitive symptoms of Alzheimer's disease: a meta-analysis
    Robin D J Harry
    University of Toronto at Scarborough, Toronto, Canada
    Hum Psychopharmacol 20:183-7. 2005
    ..However, this result does not necessarily diminish the practical value of the drug. It was also found that galantamine was no better than donepezil at treating cognitive decline in AD...
  40. ncbi request reprint An fMRI study of the Trail Making Test
    Konstantine K Zakzanis
    Department of Life Sciences, University of Toronto, Toronto, ON, Canada
    Neuropsychologia 43:1878-86. 2005
    ..However, other activity was also observed (left middle and superior temporal gyrus) reinforcing that the brain-behavior correlations for the TMT are multifaceted and not restricted to the frontal lobe...