W H Yu

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. ncbi request reprint Metallothionein III is reduced in Alzheimer's disease
    W H Yu
    Centre for Research in Neurodegenerative Diseases, University of Toronto, 6 Queen s Park Crescent West, Ontario M5S 3H2, Toronto, Canada
    Brain Res 894:37-45. 2001
  2. ncbi request reprint S100beta interaction with tau is promoted by zinc and inhibited by hyperphosphorylation in Alzheimer's disease
    W H Yu
    Centre for Research in Neurodegenerative Diseases, Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 3H2
    J Neurosci 21:2240-6. 2001
  3. ncbi request reprint Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease
    W H Yu
    Center for Dementia Research, Nathan S Kline Institute, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Int J Biochem Cell Biol 36:2531-40. 2004

Collaborators

Detail Information

Publications3

  1. ncbi request reprint Metallothionein III is reduced in Alzheimer's disease
    W H Yu
    Centre for Research in Neurodegenerative Diseases, University of Toronto, 6 Queen s Park Crescent West, Ontario M5S 3H2, Toronto, Canada
    Brain Res 894:37-45. 2001
    ..These data support the conclusion that MT-III is significantly downregulated in AD and may contribute to the loss of its protective effects and/or repair functions that lead to an exacerbation of the pathogenic processes...
  2. ncbi request reprint S100beta interaction with tau is promoted by zinc and inhibited by hyperphosphorylation in Alzheimer's disease
    W H Yu
    Centre for Research in Neurodegenerative Diseases, Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 3H2
    J Neurosci 21:2240-6. 2001
    ..S100beta-tau interaction may be disrupted by hyperphosphorylation and/or imbalances in zinc metabolism, and this may contribute to the neurite dystrophy associated with AD...
  3. ncbi request reprint Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease
    W H Yu
    Center for Dementia Research, Nathan S Kline Institute, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA
    Int J Biochem Cell Biol 36:2531-40. 2004
    ....