X Yang

Summary

Affiliation: University of Manitoba
Country: Canada

Publications

  1. Shekhar S, Peng Y, Wang S, Yang X. CD103+ lung dendritic cells (LDCs) induce stronger Th1/Th17 immunity to a bacterial lung infection than CD11bhi LDCs. Cell Mol Immunol. 2018;15:377-387 pubmed publisher
    ..In conclusion, our data provide direct evidence that CD103+ LDCs are more potent in promoting Th1/Th17 immunity to chlamydial lung infection than CD11bhi LDCs. ..
  2. Yang X, Fan Y, Wang S, Han X, Yang J, Bilenki L, et al. Mycobacterial infection inhibits established allergic inflammatory responses via alteration of cytokine production and vascular cell adhesion molecule-1 expression. Immunology. 2002;105:336-43 pubmed
    ..These findings suggest that intracellular bacterial infection can inhibit established allergic responses via alteration of local cytokine production and the expression of adhesion molecules. ..
  3. Yang X. Natural killer T (NKT) cell subsets in chlamydial infections. Adv Exp Med Biol. 2007;601:243-6 pubmed
    ..Our study provides in vivo evidence that even closely related pathogens may activate different functional NKT subsets, which can further polarize CD4+ and CD8+ cells in adaptive immune responses. ..
  4. Yang X, Gartner J, Zhu L, Wang S, Brunham R. IL-10 gene knockout mice show enhanced Th1-like protective immunity and absent granuloma formation following Chlamydia trachomatis lung infection. J Immunol. 1999;162:1010-7 pubmed
    ..These results suggest that IL-10 inhibits the priming and expansion of Th1-like T cell responses and that IL-10 plays a role in the fibrotic reaction seen with chlamydial infection. ..
  5. Yang X, Wang S, Fan Y, Han X. IL-10 deficiency prevents IL-5 overproduction and eosinophilic inflammation in a murine model of asthma-like reaction. Eur J Immunol. 2000;30:382-91 pubmed
    ..The data also argue that IL-10 may be more influential in the development of IL-5-producing Th2 cells which differ from typical Th2 cells producing both IL-4 and IL-5. ..