D George Wyse

Summary

Affiliation: University of Calgary
Country: Canada

Publications

  1. ncbi request reprint Rate control versus rhythm control--decision making
    D G Wyse
    Department of Cardiac Science, Libin Cardiovasular Institute, University of Calgary, Calgary, Alberta
    Can J Cardiol 21:15B-18B. 2005
  2. ncbi request reprint Life-threatening ventricular arrhythmias due to transient or correctable causes: high risk for death in follow-up
    D G Wyse
    Cardiology Division, University of Calgary, Calgary, Alberta, Canada
    J Am Coll Cardiol 38:1718-24. 2001
  3. doi request reprint Therapeutic considerations in applying rate control therapy for atrial fibrillation
    D George Wyse
    Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary Calgary Health Region, Health Sciences Center, Calgary, Alberta, Canada
    J Cardiovasc Pharmacol 52:11-7. 2008
  4. ncbi request reprint Rhythm versus rate control trials in atrial fibrillation
    D George Wyse
    Department of Cardiac Sciences, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
    J Cardiovasc Electrophysiol 14:S35-9. 2003
  5. ncbi request reprint What is the best method of detecting atrial fibrillation in people aged 65 years and older?
    D George Wyse
    Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary Calgary Health Region, Calgary, AB, Canada
    Nat Clin Pract Cardiovasc Med 5:138-9. 2008
  6. ncbi request reprint Some recent randomized clinical trials in the management of atrial fibrillation
    D George Wyse
    Division of Cardiology, Department of Cardiac Sciences, University of Calgary Calgary Health Region, Room G009 Health Sciences Center, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
    J Interv Card Electrophysiol 9:223-8. 2003
  7. ncbi request reprint In the wake of the AFFIRM trial: what we still don't know about the management of atrial fibrillation and where we need to go
    D George Wyse
    Department of Cardiac Sciences, Division of Cardiology, University of Calgary Health Sciences Center, Room G009, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
    Card Electrophysiol Rev 7:130-5. 2003
  8. ncbi request reprint Rate control vs rhythm control strategies in atrial fibrillation
    D George Wyse
    Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
    Prog Cardiovasc Dis 48:125-38. 2005
  9. ncbi request reprint Atrial fibrillation: a perspective: thinking inside and outside the box
    D George Wyse
    Department of Cardiac Sciences, University of Calgary and Libin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada
    Circulation 109:3089-95. 2004
  10. ncbi request reprint Anticoagulation in atrial fibrillation: a contemporary viewpoint
    D George Wyse
    Libin Cardiovascular Institute of Alberta, University of Calgary, and Calgary Health Region, Calgary, Alberta, Canada
    Heart Rhythm 4:S34-9. 2007

Detail Information

Publications69

  1. ncbi request reprint Rate control versus rhythm control--decision making
    D G Wyse
    Department of Cardiac Science, Libin Cardiovasular Institute, University of Calgary, Calgary, Alberta
    Can J Cardiol 21:15B-18B. 2005
    ..It is also recommended that treating physicians be prepared to cross over from one strategy to another or change to nonpharmacological therapies when treatment goals are not achieved or adverse effects prevail...
  2. ncbi request reprint Life-threatening ventricular arrhythmias due to transient or correctable causes: high risk for death in follow-up
    D G Wyse
    Cardiology Division, University of Calgary, Calgary, Alberta, Canada
    J Am Coll Cardiol 38:1718-24. 2001
    ..This study evaluated the prognosis of patients resuscitated from ventricular tachycardia (VT) or ventricular fibrillation (VF) with a transient or correctable cause suspected as the cause of the VT/VF...
  3. doi request reprint Therapeutic considerations in applying rate control therapy for atrial fibrillation
    D George Wyse
    Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary Calgary Health Region, Health Sciences Center, Calgary, Alberta, Canada
    J Cardiovasc Pharmacol 52:11-7. 2008
    ..Nevertheless, it remains to be demonstrated through randomized clinical trials how to apply various heart rate control targets in patients with AF and whether complexity offers any advantage over simplicity...
  4. ncbi request reprint Rhythm versus rate control trials in atrial fibrillation
    D George Wyse
    Department of Cardiac Sciences, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
    J Cardiovasc Electrophysiol 14:S35-9. 2003
    ..The results underscore the importance of continuous anticoagulation in patients with stroke risk factors. Finally, the results from these trials help to set the agenda for future research on rhythm management in atrial fibrillation...
  5. ncbi request reprint What is the best method of detecting atrial fibrillation in people aged 65 years and older?
    D George Wyse
    Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary Calgary Health Region, Calgary, AB, Canada
    Nat Clin Pract Cardiovasc Med 5:138-9. 2008
  6. ncbi request reprint Some recent randomized clinical trials in the management of atrial fibrillation
    D George Wyse
    Division of Cardiology, Department of Cardiac Sciences, University of Calgary Calgary Health Region, Room G009 Health Sciences Center, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
    J Interv Card Electrophysiol 9:223-8. 2003
    ..Finally, primary prevention of atrial fibrillation needs more attention. Recent randomized trials with trandolapril after myocardial infarction and physiologic pacing have given some insight into how this might be accomplished...
  7. ncbi request reprint In the wake of the AFFIRM trial: what we still don't know about the management of atrial fibrillation and where we need to go
    D George Wyse
    Department of Cardiac Sciences, Division of Cardiology, University of Calgary Health Sciences Center, Room G009, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
    Card Electrophysiol Rev 7:130-5. 2003
    ..These and other research efforts are needed to make an impact on management of the problems of atrial fibrillation...
  8. ncbi request reprint Rate control vs rhythm control strategies in atrial fibrillation
    D George Wyse
    Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
    Prog Cardiovasc Dis 48:125-38. 2005
    ..Finally, some of the possibilities for future research around this question are highlighted...
  9. ncbi request reprint Atrial fibrillation: a perspective: thinking inside and outside the box
    D George Wyse
    Department of Cardiac Sciences, University of Calgary and Libin Cardiovascular Institute of Alberta, Calgary, Alberta, Canada
    Circulation 109:3089-95. 2004
  10. ncbi request reprint Anticoagulation in atrial fibrillation: a contemporary viewpoint
    D George Wyse
    Libin Cardiovascular Institute of Alberta, University of Calgary, and Calgary Health Region, Calgary, Alberta, Canada
    Heart Rhythm 4:S34-9. 2007
    ..The two most pressing needs for further investigation are (1) clarification, simplification, and consolidated of risk stratification schemes and treatment recommendations and (2) discovery of alternatives to warfarin...
  11. ncbi request reprint Overview of endpoints in atrial fibrillation studies
    D George Wyse
    Department of Cardiac Sciences and Libin Cardiovascular Institute of Alberta, University of Calgary, G009 Health Sciences Center, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
    Heart Rhythm 1:B3-7, discussion B7. 2004
    ..More research on the validity of some of these endpoints is needed if we are to advance our knowledge of the management of atrial fibrillation in a meaningful way...
  12. ncbi request reprint Pharmacologic approaches to rhythm versus rate control in atrial fibrillation--where are we now?
    D George Wyse
    Libin Cardiovascular Institute of Alberta, Department of Cardiac Sciences, University of Calgary Calgary Health Region, Calgary, Alberta, Canada
    Int J Cardiol 110:301-12. 2006
    ..The lack of appropriately designed and controlled trials at this time makes it difficult to determine the place of radiofrequency ablation and its impact on the rhythm versus rate question...
  13. ncbi request reprint Can recent-onset atrial fibrillation be safely and successfully treated with self-administered antiarrhythmic drugs?
    D George Wyse
    Cardiac Sciences, Medicine and Pharmacology and Therapeutics at the Libin Cardiovascular Institute of Alberta, University of Calgary and the Calgary Health Region, Calgary, Alberta, Canada
    Nat Clin Pract Cardiovasc Med 2:132-3. 2005
  14. doi request reprint Pharmacotherapy for rhythm management in elderly patients with atrial fibrillation
    D George Wyse
    Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary Calgary Health Region, Room G009, Health Sciences Center, 3350 Hospital Drive NW, Calgary, AB, Canada, T2N 4N1
    J Interv Card Electrophysiol 25:25-9. 2009
    ....
  15. ncbi request reprint Antiarrhythmic drug therapy in the Multicenter UnSustained Tachycardia Trial (MUSTT): drug testing and as-treated analysis
    D G Wyse
    Division of Cardiology, University of Calgary, Health Science Center, Alberta, Canada
    J Am Coll Cardiol 38:344-51. 2001
    ..Using data from the Multicenter UnSustained Tachycardia Trial (MUSTT), we examined the factors used to select antiarrhythmic drug therapy and their impact on outcomes...
  16. ncbi request reprint The AFFIRM trial: main trial and substudies-what can We expect?
    D G Wyse
    University of Calgary Calgary Regional Health Authority, Calgary, Canada
    J Interv Card Electrophysiol 4:171-6. 2000
    ..The AFFIRM Trial will provide important information concerning the management of atrial fibrillation in a large portion of the patients who have this arrhythmia...
  17. ncbi request reprint Atrial fibrillation: a risk factor for increased mortality--an AVID registry analysis
    D G Wyse
    Division of Cardiology, University of Calgary, Calgary, Canada
    J Interv Card Electrophysiol 5:267-73. 2001
    ..This risk may have been overestimated in previous studies that could not adjust for the proarrhythmic effects of antiarrhythmic drugs other than amiodarone or sotalol...
  18. ncbi request reprint Are there alternatives to mortality as an endpoint in clinical trials of atrial fibrillation?
    D George Wyse
    Department of Cardiac Sciences and Libin Cardiovascular Institute of Alberta, University of Calgary, G009 Health Sciences Center, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
    Heart Rhythm 1:B41-4, discussion B44. 2004
    ..However, there are limitations in the AFFIRM data on these points. More research is needed to define suitable alternatives to death as an endpoint for trials in a broad spectrum of patients with AF...
  19. ncbi request reprint Selection of endpoints in atrial fibrillation studies
    D George Wyse
    Division of Cardiology, University of Calgary Calgary Regional Health Authority, Alberta, Canada
    J Cardiovasc Electrophysiol 13:S47-52. 2002
    ..More research on these issues is urgently needed...
  20. ncbi request reprint Randomized controlled trial of fixed rate versus rate responsive pacing after radiofrequency atrioventricular junction ablation: quality of life, ventricular refractoriness, and paced QT dispersion
    Henry J Duff
    Cardiovascular Disease Research Group, University of Calgary Health Sciences Centre, HSC 1632, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1
    J Cardiovasc Electrophysiol 14:1163-70. 2003
    ..The aim of this study was to provide information about the balance between measures of quality of life versus measures of electrical remodeling achieved by pacing with different rate modalities in a randomized pilot clinical trial...
  21. doi request reprint Validation of a new simple scale to measure symptoms in atrial fibrillation: the Canadian Cardiovascular Society Severity in Atrial Fibrillation scale
    Paul Dorian
    Division of Cardiology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Circ Arrhythm Electrophysiol 2:218-24. 2009
    ..This study was performed to validate the scale...
  22. ncbi request reprint Paced QT dispersion and QT morphology after radiofrequency atrioventricular junction ablation: impact of left ventricular function
    Satish R Raj
    Division of Cardiology, Foothills Medical Center and the Cardiovascular Disease Research Group, University of Calgary, Calgary, Alberta, Canada
    Pacing Clin Electrophysiol 26:662-8. 2003
    ..02) function groups. Following AVJ ablation, QTdisp increased during a sudden rate drop in patients with reduced LV function, but not in patients with normal LV function...
  23. doi request reprint Beneficial effects of statin therapy for prevention of atrial fibrillation following DDDR pacemaker implantation
    Anne M Gillis
    Department of Cardiac Sciences, Libin Cardiovascular Institute of Alberta, University of Calgary and Calgary Health Region, Calgary, AB, Canada
    Eur Heart J 29:1873-80. 2008
    ..The clinical predictors of at/af recurrence following dual-chamber pacemaker insertion were examined in 185 consecutive patients with paroxysmal AF...
  24. ncbi request reprint Alternative endpoints for mortality in studies of patients with atrial fibrillation: the AFFIRM study experience
    D George Wyse
    Libin Cardiovascular Institute of Alberta, University of Calgary, Canada
    Heart Rhythm 1:531-7. 2004
    ....
  25. ncbi request reprint Medical management of atrial fibrillation
    Ahmad Hersi
    The Libin Cardiovascular Institute of Alberta, University of Calgary, Room G009, 3330 Hospital Drive NW, Calgary AB, T2N 4N1, Canada
    Curr Cardiol Rep 8:323-9. 2006
    ..This article summarizes the results of many of the recent publications and their clinical implications concerning management of this common rhythm disorder...
  26. ncbi request reprint Clinical and electrophysiologic predictors of ventricular tachyarrhythmia recurrence in patients with implantable cardioverter defibrillators
    Anne M Gillis
    Division of Cardiology, Foothills Hospital and Cardiovascular Research Group, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    J Cardiovasc Electrophysiol 14:492-8. 2003
    ..We evaluated the clinical and electrophysiologic predictors of ventricular tachycardia (VT) and ventricular fibrillation (VF) recurrence following ICD implantation...
  27. ncbi request reprint Total atrioventricular nodal ablation increases atrial fibrillation burden in patients with paroxysmal atrial fibrillation despite continuation of antiarrhythmic drug therapy
    Rik Willems
    Division of Cardiology, University of Calgary, AB, Canada
    J Cardiovasc Electrophysiol 14:1296-301. 2003
    ..This usually is ascribed to the cessation of antiarrhythmic drug therapy. We hypothesized that TAVN ablation itself creates an atrial substrate prone to AF...
  28. ncbi request reprint Precordial QT dispersion does not predict inducibility of ventricular tachyarrhythmias at post-revascularization electrophysiologic study
    Satish R Raj
    Division of Cardiology, Foothills Medical Centre and the Cardiovascular Disease Research Group, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta, Canada, T2N 4N1
    J Interv Card Electrophysiol 6:25-33. 2002
    ..We tested the hypothesis that revascularization would decrease QT interval dispersion and that QT interval dispersion would predict the outcome of the electrophysiologic study following revascularization...
  29. pmc A novel, simple scale for assessing the symptom severity of atrial fibrillation at the bedside: the CCS-SAF scale
    Paul Dorian
    Division of Cardiology, St Michael s Hospital, University of Toronto, Ontario, Canada
    Can J Cardiol 22:383-6. 2006
    ..Quantifying the effect of AF on patient well-being is important but there is no simple, commonly accepted measure of the effect of AF on quality of life (QoL). Current QoL measures are cumbersome and impractical for clinical use...
  30. pmc Atrial fibrillation: challenges and opportunities
    Ahmad Hersi
    Libin Cardiovascular Institute of Alberta, University of Calgary, and Calgary Health Region, Alberta
    Can J Cardiol 22:21C-26C. 2006
    ..Furthermore, AF management remains associated with many challenges that make the treatment of AF a vexing problem. The present overview discusses these challenges and explores the opportunities associated with them...
  31. ncbi request reprint Atrial pacing periablation for prevention of paroxysmal atrial fibrillation
    A M Gillis
    Division of Cardiology, The University of Calgary, Calgary, Alberta, Canada
    Circulation 99:2553-8. 1999
    ..This study tested the hypothesis that rate-adaptive atrial pacing would prevent paroxysmal atrial fibrillation (PAF) in patients with frequent PAF in the absence of symptomatic bradycardia...
  32. ncbi request reprint Ambulatory electrocardiography for the detection of pacemaker lead failure
    A M Gillis
    Pacemaker Clinic, Foothills Hospital, Calgary, Alberta, Canada
    Pacing Clin Electrophysiol 20:1274-82. 1997
    ..AECG is a more sensitive method of surveillance for pacemaker lead function compared to pacemaker clinic assessment. AECG should be incorporated into the routine follow-up of pacemaker patients...
  33. ncbi request reprint Conduction time oscillations precede the spontaneous termination of human atrioventricular reciprocating tachycardia
    D V Exner
    Department of Medicine, Division of Cardiology, University of Calgary, Canada
    J Interv Card Electrophysiol 4:231-9. 2000
    ..002. Conduction time oscillations, which are related to apparent enhancement in atrio-His or ventriculoatrial conduction, frequently precede the spontaneous termination of reentry in humans...
  34. ncbi request reprint Electrical storm presages nonsudden death: the antiarrhythmics versus implantable defibrillators (AVID) trial
    D V Exner
    University of Calgary, Canada
    Circulation 103:2066-71. 2001
    ..However, insufficient data exist regarding its prognostic significance...
  35. doi request reprint Design and use of a quantitative scale for measuring presyncope
    Robert S Sheldon
    Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada
    J Cardiovasc Electrophysiol 20:888-93. 2009
    ..One important symptom is presyncope, but there are no clinimetric measures of this. We developed the Calgary Presyncope Form (CPF) and used it to test whether metoprolol reduces presyncope in a randomized trial...
  36. doi request reprint Effect of metoprolol on quality of life in the Prevention of Syncope Trial
    Robert S Sheldon
    University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
    J Cardiovasc Electrophysiol 20:1083-8. 2009
    ..No therapies have proven useful to improve quality of life in adequately designed randomized clinical trials. Beta-blockers have mixed evidence for effectiveness in preventing syncope...
  37. ncbi request reprint Prophylactic Oral Amiodarone for the Prevention of Arrhythmias that Begin Early After Revascularization, Valve Replacement, or Repair: PAPABEAR: a randomized controlled trial
    L Brent Mitchell
    Libin Cardiovascular Institute of Alberta, Calgary, Alberta
    JAMA 294:3093-100. 2005
    ..Atrial tachyarrhythmias after cardiac surgery are associated with adverse outcomes and increased costs. Previous trials of amiodarone prophylaxis, while promising, were relatively small and yielded conflicting results...
  38. pmc Treating the right patient at the right time: an innovative approach to the management of atrial fibrillation
    Anne M Gillis
    Libin Cardiovascular Institute of Alberta and Department of Cardiac Sciences, University of Calgary and Calgary Health Region, Calgary, Alberta
    Can J Cardiol 24:195-8. 2008
    ..This experience suggests that a nurse clinician-based AF clinic may provide earlier access to medical care and may improve health outcomes in the long term...
  39. ncbi request reprint Chelation therapy for ischemic heart disease: a randomized controlled trial
    Merril L Knudtson
    Foothills Medical Center, 1403 29th St NW, Calgary, Alberta, Canada T2N 2T9
    JAMA 287:481-6. 2002
    ..Chelation therapy using EDTA is an unproven but widely used alternative therapy for ischemic heart disease...
  40. ncbi request reprint Life threatening ventricular arrhythmias with transient or correctable causes
    G D Veenhuyzen
    Division of Cardiology, Department of Cardiac Sciences, University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
    Minerva Cardioangiol 51:275-86. 2003
    ..Accordingly, physicians should use extreme caution in attributing life-threatening ventricular tachyarrhythmias to these 3 conditions. Further research is required to identify "truly reversible" causes of VT/VF...
  41. ncbi request reprint Events in the Cardiac Arrhythmia Suppression Trial (CAST): mortality in patients surviving open label titration but not randomized to double-blind therapy
    D G Wyse
    Department of Medicine, Foothills Hospital, Calgary, Alberta, Canada
    J Am Coll Cardiol 18:20-8. 1991
    ..abstract truncated at 250 words)..
  42. ncbi request reprint Does intensity of rate-control influence outcome in atrial fibrillation? An analysis of pooled data from the RACE and AFFIRM studies
    Isabelle C Van Gelder
    Department of Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Europace 8:935-42. 2006
    ..The AFFIRM and RACE studies showed that rate control is an acceptable treatment strategy for atrial fibrillation (AF). We examined whether strict rate control offers benefit over more lenient rate control...
  43. doi request reprint Rhythm control versus rate control for atrial fibrillation and heart failure
    Denis Roy
    Montreal Heart Institute and the Université de Montréal, Montreal, QC H1T 1C8, Canada
    N Engl J Med 358:2667-77. 2008
    ..However, the benefits and risks of this approach have not been adequately studied...
  44. ncbi request reprint Rhythm management in atrial fibrillation: less is more
    D George Wyse
    J Am Coll Cardiol 41:1703-6. 2003
  45. ncbi request reprint Comparison of management patterns and clinical outcomes in patients with atrial fibrillation in Canada and the United States (from the analysis of the Atrial Fibrillation Follow-up Investigation of Rhythm Management [AFFIRM] database)
    Gilles E O'Hara
    Institut de Cardiologie, Hopital Laval, Quebec, Quebec, Canada
    Am J Cardiol 96:815-21. 2005
    ..Effective warfarin therapy was more commonly employed in Canada. After correcting for the known differences in baseline characteristics, Canadian patients who had atrial fibrillation had a lower mortality risk...
  46. ncbi request reprint Bleeding while starting anticoagulation for thromboembolism prophylaxis in elderly patients with atrial fibrillation: from bad to worse
    D George Wyse
    Circulation 115:2684-6. 2007
  47. ncbi request reprint Analysis of implantable cardioverter defibrillator therapy in the Antiarrhythmics Versus Implantable Defibrillators (AVID) Trial
    Richard C Klein
    Cardiology Division, University of Utah Health Sciences Center and VA Medical Center, 50 N Medical Drive, Salt Lake City, UT 84132, USA
    J Cardiovasc Electrophysiol 14:940-8. 2003
    ..Arrhythmia recurrence rates in these patients are high, but which patients will receive a therapy and the forms of arrhythmia recurrence (VT or VF) are poorly understood...
  48. ncbi request reprint Monitoring the ACTIVE-W trial: some issues in monitoring a noninferiority trial
    John A Cairns
    University of British Columbia, Vancouver, British Columbia, Canada
    Am Heart J 155:33-41. 2008
    ....
  49. doi request reprint ACC/AHA/Physician Consortium 2008 clinical performance measures for adults with nonvalvular atrial fibrillation or atrial flutter: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and the Physici
    N A Mark Estes
    Circulation 117:1101-20. 2008
  50. ncbi request reprint Cost-effectiveness of rhythm versus rate control in atrial fibrillation
    Deborah A Marshall
    Center for Evaluation of Medicine, McMaster University and St Joseph s Hospital, Hamilton, Ontario, Canada
    Ann Intern Med 141:653-61. 2004
    ..Consequently, economic factors often play a role in guiding treatment selection...
  51. ncbi request reprint Introduction. Management of atrial fibrillation in elderly patients
    D George Wyse
    Am J Geriatr Cardiol 14:54-5. 2005
  52. ncbi request reprint Improved suppression of recurrent atrial fibrillation with dual-site right atrial pacing and antiarrhythmic drug therapy
    Sanjeev Saksena
    Cardiovascular Institute, Atlantic Health System, Passaic, New Jersey 07055, USA
    J Am Coll Cardiol 40:1140-50; discussion 1151-2. 2002
    ..We compared the safety, tolerance and effectiveness of overdrive high right atrial (RA), dual-site RA and support (DDI or VDI) pacing (SP) in patients with symptomatic atrial fibrillation (AF) and bradycardias...
  53. ncbi request reprint Clinical factors that influence response to treatment strategies in atrial fibrillation: the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study
    Anne B Curtis
    University of Florida, Box 100277, 1600 SW Archer Rd, Gainesville, FL 32610, USA
    Am Heart J 149:645-9. 2005
    ..The primary outcome of the trial showed no overall difference in survival between strategies. However, there may be important patient subgroups for which there are identifiable differences in outcome with 1 of the 2 strategies...
  54. ncbi request reprint Relationships between sinus rhythm, treatment, and survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study
    Scott D Corley
    Axio Research Corporation, Seattle, Wash, USA
    Circulation 109:1509-13. 2004
    ..This article reports an "on-treatment" analysis of the relationship of survival to cardiac rhythm and treatment as they changed over time...
  55. ncbi request reprint Relation of ejection fraction and inducible ventricular tachycardia to mode of death in patients with coronary artery disease: an analysis of patients enrolled in the multicenter unsustained tachycardia trial
    Alfred E Buxton
    Brown Medical School, Providence, RI, USA
    Circulation 106:2466-72. 2002
    ..As such, optimum methods to determine patients most likely to benefit from implantable defibrillator therapy are unclear...
  56. ncbi request reprint Functional status in rate- versus rhythm-control strategies for atrial fibrillation: results of the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Functional Status Substudy
    Mina K Chung
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 46:1891-9. 2005
    ..The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) functional status substudy aimed to test the hypothesis that functional status is similar in rate-control and rhythm-control strategies...
  57. ncbi request reprint Comparison of arrhythmia recurrence in patients presenting with ventricular fibrillation versus ventricular tachycardia in the Antiarrhythmics Versus Implantable Defibrillators (AVID) trial
    Merritt H Raitt
    Portland VA Medical Center, Oregon Health and Science University, Portland, Oregon, USA
    Am J Cardiol 91:812-6. 2003
    ..These findings suggest there are important differences in the electrophysiologic characteristics of these 2 patient populations...
  58. ncbi request reprint Rationale and design of a prospective study of the clinical significance of atrial arrhythmias detected by implanted device diagnostics: the TRENDS study
    Taya V Glotzer
    Hackensack University Medical Center, Hackensack, NJ, USA
    J Interv Card Electrophysiol 15:9-14. 2006
    ..Improved assessment of the impact of AF burden on stroke risk will allow more targeted and safer use of antithrombotic therapy...
  59. ncbi request reprint International consensus on nomenclature and classification of atrial fibrillation: A collaborative project of the Working Group on Arrhythmias and the Working Group of Cardiac Pacing of the European Society of Cardiology and the North American Society of
    Samuel Levy
    Hopital Nord, Division of Cardiology, 13015 Marseille, France
    J Cardiovasc Electrophysiol 14:443-5. 2003
  60. doi request reprint Vernakalant hydrochloride for rapid conversion of atrial fibrillation: a phase 3, randomized, placebo-controlled trial
    Denis Roy
    Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada
    Circulation 117:1518-25. 2008
    ..The present study assessed the efficacy and safety of vernakalant hydrochloride (RSD1235), a novel compound, for the conversion of atrial fibrillation (AF)...
  61. doi request reprint ACC/AHA/Physician Consortium 2008 Clinical Performance Measures for Adults with Nonvalvular Atrial Fibrillation or Atrial Flutter: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and the Physici
    N A Mark Estes
    J Am Coll Cardiol 51:865-84. 2008
  62. ncbi request reprint Economics of managing atrial fibrillation: broadening the focus to include efficiency
    D George Wyse
    J Cardiovasc Electrophysiol 18:634-5. 2007
  63. ncbi request reprint ACC/AHA key data elements and definitions for measuring the clinical management and outcomes of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Com
    Robert L McNamara
    Circulation 109:3223-43. 2004
  64. ncbi request reprint ACC/AHA key data elements and definitions for measuring the clinical management and outcomes of patients with atrial fibrillation: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Com
    Robert L McNamara
    J Am Coll Cardiol 44:475-95. 2004
  65. ncbi request reprint Overview of symposium: outcomes in AF trials
    Rahul Mehra
    Medtronic Inc, 7000 Central Avenue NE, Mailstop B170, Minneapolis, MN 55432 3576, USA
    Heart Rhythm 1:B1-2. 2004
  66. ncbi request reprint Dual site right atrial pacing can improve the impact of standard dual chamber pacing on atrial and ventricular mechanical function in patients with symptomatic atrial fibrillation: further observations from the dual site atrial pacing for prevention of at
    Atul Prakash
    Echocardiography Core Laboratory, Electrophysiology Research Foundation, Warren, NJ 07059, USA
    J Interv Card Electrophysiol 12:177-87. 2005
    ..We evaluated atrial and ventricular function during randomization to support pacing (SP), high right atrial pacing (HRA), and dual site right atrial pacing (DAP)...
  67. ncbi request reprint Conflict of interest-draining the swamp means confronting alligators
    D George Wyse
    J Interv Card Electrophysiol 13:5-7. 2005
  68. ncbi request reprint The Euro Heart Survey on atrial fibrillation: a picture and a thousand words
    D George Wyse
    Eur Heart J 26:2356-7. 2005
  69. ncbi request reprint Transvenous radiofrequency catheter ablation for atrial flutter and atrial fibrillation: the end of the beginning?
    D George Wyse
    Circulation 114:1670-2. 2006