James M Wright

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. pmc Choosing a first-line drug in the management of elevated blood pressure: what is the evidence? 1: Thiazide diuretics
    J M Wright
    Department of Medicine, University of British Columbia, Vancouver
    CMAJ 163:57-60. 2000
  2. pmc Are the benefits of statins a class effect?
    James M Wright
    Department of Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC
    CMAJ 172:1195-6. 2005
  3. pmc Why don't we initiate more large simple randomized controlled trials?
    James M Wright
    Department of Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC
    CMAJ 169:1170-1. 2003
  4. pmc The double-edged sword of COX-2 selective NSAIDs
    James M Wright
    Department of Pharmacology and Therapeutics, University of British Columbia, Vancouver Hospital, UBC Site, Vancouver, BC
    CMAJ 167:1131-7. 2002
  5. pmc Choosing a first-line drug in the management of elevated blood pressure: what is the evidence? 2: Beta-blockers
    J M Wright
    Department of Medicine, University of British Columbia, Vancouver
    CMAJ 163:188-92. 2000
  6. ncbi request reprint Validation of a new algorithm for the BPM-100 electronic oscillometric office blood pressure monitor
    J M Wright
    Department of Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada
    Blood Press Monit 6:161-5. 2001
  7. pmc Choosing a first-line drug in the management of elevated blood pressure: what is the evidence? 3: Angiotensin-converting-enzyme inhibitors
    J M Wright
    Department of Medicine, University of British Columbia, Vancouver
    CMAJ 163:293-6. 2000
  8. pmc Rosiglitazone and myocardial infarction in patients previously prescribed metformin
    Colin R Dormuth
    Therapeutics Initiative, University of British Columbia, Vancouver, Canada
    PLoS ONE 4:e6080. 2009
  9. ncbi request reprint Overall accuracy of the BpTRU--an automated electronic blood pressure device
    Gurdial S Mattu
    Department of Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada
    Blood Press Monit 9:47-52. 2004
  10. pmc Statin adherence and risk of accidents: a cautionary tale
    Colin R Dormuth
    Therapeutics Initiative, and Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Victoria, BC, Canada
    Circulation 119:2051-7. 2009

Collaborators

Detail Information

Publications31

  1. pmc Choosing a first-line drug in the management of elevated blood pressure: what is the evidence? 1: Thiazide diuretics
    J M Wright
    Department of Medicine, University of British Columbia, Vancouver
    CMAJ 163:57-60. 2000
    ..The evidence indicates that low-dose thiazides are preferable to high-dose thiazides and that low-dose thiazides are better than or equivalent to other antihypertensive drugs for each of the goals of therapy...
  2. pmc Are the benefits of statins a class effect?
    James M Wright
    Department of Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC
    CMAJ 172:1195-6. 2005
  3. pmc Why don't we initiate more large simple randomized controlled trials?
    James M Wright
    Department of Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC
    CMAJ 169:1170-1. 2003
  4. pmc The double-edged sword of COX-2 selective NSAIDs
    James M Wright
    Department of Pharmacology and Therapeutics, University of British Columbia, Vancouver Hospital, UBC Site, Vancouver, BC
    CMAJ 167:1131-7. 2002
    ....
  5. pmc Choosing a first-line drug in the management of elevated blood pressure: what is the evidence? 2: Beta-blockers
    J M Wright
    Department of Medicine, University of British Columbia, Vancouver
    CMAJ 163:188-92. 2000
    ..The evidence indicates that beta-blockers are probably not as effective in reducing morbidity and mortality as low-dose thiazide diuretics and that there may be significant differences in effectiveness among various beta-blockers...
  6. ncbi request reprint Validation of a new algorithm for the BPM-100 electronic oscillometric office blood pressure monitor
    J M Wright
    Department of Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada
    Blood Press Monit 6:161-5. 2001
    ..To test the accuracy of a new algorithm for the BPM-100, an automated oscillometric blood pressure (BP) monitor, using stored data from an independently conducted validation trial comparing the BPM-100(Beta) with a mercury sphygmomanometer...
  7. pmc Choosing a first-line drug in the management of elevated blood pressure: what is the evidence? 3: Angiotensin-converting-enzyme inhibitors
    J M Wright
    Department of Medicine, University of British Columbia, Vancouver
    CMAJ 163:293-6. 2000
    ....
  8. pmc Rosiglitazone and myocardial infarction in patients previously prescribed metformin
    Colin R Dormuth
    Therapeutics Initiative, University of British Columbia, Vancouver, Canada
    PLoS ONE 4:e6080. 2009
    ..Our objective is to estimate the magnitude of the association in real-world patients previously treated with metformin...
  9. ncbi request reprint Overall accuracy of the BpTRU--an automated electronic blood pressure device
    Gurdial S Mattu
    Department of Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada
    Blood Press Monit 9:47-52. 2004
    ....
  10. pmc Statin adherence and risk of accidents: a cautionary tale
    Colin R Dormuth
    Therapeutics Initiative, and Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Victoria, BC, Canada
    Circulation 119:2051-7. 2009
    ..We sought evidence of this bias by examining associations between statin exposure and various outcomes that should not be causally affected by statin exposure, such as workplace and motor vehicle accidents...
  11. doi request reprint Blood pressure lowering efficacy of potassium-sparing diuretics (that block the epithelial sodium channel) for primary hypertension
    Balraj S Heran
    Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada
    Cochrane Database Syst Rev 11:CD008167. 2012
    ..Therefore, it is essential to determine the effects of ENaC blockers on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAEs) when given as a first-line or second-line therapy...
  12. pmc Influence of relative age on diagnosis and treatment of attention-deficit/hyperactivity disorder in children
    Richard L Morrow
    Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Victoria, BC
    CMAJ 184:755-62. 2012
    ..We sought to determine the influence of relative age within a grade on the diagnosis and pharmacologic treatment of attention-deficit/hyperactivity disorder (ADHD) in children...
  13. doi request reprint Blood pressure lowering efficacy of loop diuretics for primary hypertension
    Vijaya M Musini
    Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada
    Cochrane Database Syst Rev 8:CD003825. 2012
    ....
  14. pmc First-line first? Trends in thiazide prescribing for hypertensive seniors
    Steve Morgan
    Centre for Health Services and Policy Research, University of British Columbia, Vancouver, Canada
    PLoS Med 2:e80. 2005
    ....
  15. doi request reprint Blood pressure lowering efficacy of alpha blockers for primary hypertension
    Balraj S Heran
    Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, British Columbia, Canada
    Cochrane Database Syst Rev 8:CD004643. 2012
    ..Alpha blockers are occasionally prescribed for hypertension so it is important to determine and compare their effects on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAE)...
  16. ncbi request reprint Comparison of the automated non-invasive oscillometric blood pressure monitor (BpTRU) with the auscultatory mercury sphygmomanometer in a paediatric population
    Gurdial S Mattu
    Department of Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada
    Blood Press Monit 9:39-45. 2004
    ..To directly compare the accuracy of the BpTRU (an automated oscillometric blood pressure device) with standard auscultatory mercury sphygmomanometry in a pediatric population...
  17. doi request reprint Thiazolidinediones and fractures in men and women
    Colin R Dormuth
    Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Victoria, BC V8W 1Y2, Canada
    Arch Intern Med 169:1395-402. 2009
    ..The association between the use of thiazolidinediones and fractures in men and women is not adequately understood...
  18. doi request reprint Comparative effectiveness of tiotropium and ipratropium in prevention of hospital readmission for COPD: a population-based cohort study
    Yuko Kawasumi
    Therapeutics Initiative, Department of Anesthesiology, Pharmacology and Therapeutics, The University of British Columbia, Vancouver, BC, Canada
    Clin Ther 35:523-531.e1. 2013
    ..At issue is whether tiotropium reduces the risk for hospital readmissions for COPD compared with ipratropium...
  19. doi request reprint Pharmacotherapy for mild hypertension
    Diana Diao
    Faculty of Medicine, University of British Columbia, Vancouver, Canada
    Cochrane Database Syst Rev 8:CD006742. 2012
    ..The benefits and harms of treating mild hypertension in primary prevention patients are not known at present. This review examines the existing randomised controlled trial (RCT) evidence...
  20. doi request reprint Angiotensin receptor blockers for heart failure
    Balraj S Heran
    Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada
    Cochrane Database Syst Rev 4:CD003040. 2012
    ..Chronic heart failure (HF) is a prevalent world-wide. Angiotensin receptor blockers (ARBs) are widely prescribed for chronic HF although their role is controversial...
  21. pmc "Breakthrough" drugs and growth in expenditure on prescription drugs in Canada
    Steven G Morgan
    Centre for Health Services and Policy Research, University of British Columbia, 429 2194 Health Sciences Mall, Vancouver, BC, Canada V6T 1Z3
    BMJ 331:815-6. 2005
  22. pmc Progressive drug licensing: an opportunity to achieve transparency and accountability?
    James M Wright
    Department of Medicine, University Hospital, UBC Site, Vancouver, BC
    CMAJ 176:1848-9. 2007
  23. pmc Factors affecting blood pressure variability: lessons learned from two systematic reviews of randomized controlled trials
    Vijaya M Musini
    Department of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 4:e5673. 2009
    ..Entry criterion decreases the baseline blood pressure variability. Treatment with a thiazide diuretic does not affect blood pressure variability. Systolic blood pressure varies to a greater degree than diastolic blood pressure...
  24. pmc Twelve years' experience with direct-to-consumer advertising of prescription drugs in Canada: a cautionary tale
    Barbara Mintzes
    Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, Canada Barbara Mintzes
    PLoS ONE 4:e5699. 2009
    ..We ask how annual per capita spending compares to that in the US, and whether drugs with Canadian or US regulatory safety warnings are advertised to the Canadian public in reminder advertising...
  25. pmc Effect of periodic letters on evidence-based drug therapy on prescribing behaviour: a randomized trial
    Colin R Dormuth
    Therapeutics Initiative, University of British Columbia, Vancouver
    CMAJ 171:1057-61. 2004
    ..We sought to measure the impact of a series of evidence-based drug therapy letters mailed to physicians in British Columbia on prescribing to newly treated patients...
  26. ncbi request reprint Withdraw all COX-2-selective drugs
    Peter R Mansfield
    Med J Aust 182:197; author reply 199. 2005
  27. pmc Drug safety without borders: concerns about bupropion
    Barbara Mintzes
    CMAJ 167:447. 2002
  28. ncbi request reprint The 2001 Canadian recommendations for the management of hypertension: Part two--Therapy
    Finlay A McAlister
    University of Alberta Hospital, Edmonton, Canada
    Can J Cardiol 18:625-41. 2002
    ..To provide updated, evidence-based recommendations for the therapy of hypertension in adults...
  29. ncbi request reprint Y Moride, RA Hegele, A Langer, R McPherson, DB Miller, S Rinfret. Clinical and public health assessment of benefits and risks of statins in primary prevention of coronary events: Resolved and unresolved issues. Can J Cardiol 2008;24(4):293-300
    James McCormack
    Can J Cardiol 24:615. 2008
  30. pmc Assessing the quality of clinical practice guidelines
    James McCormack
    CMAJ 166:168; author reply 169. 2002
  31. doi request reprint New insights on the relation between untreated and treated outcomes for a given therapy effect model is not necessarily linear
    Jean Pierre Boissel
    Institute for Theoretical Medicine and CNRS UMR5558, RTH Laennec School of Medicine, Rue Guillaume Paradin, 69008 Lyon, France
    J Clin Epidemiol 61:301-7. 2008
    ..We have called this relation the effect model. Our objectives were to demonstrate that the relation is general and not necessarily linear...