Elaine Wirrell

Summary

Affiliation: University of Calgary
Country: Canada

Publications

  1. ncbi request reprint How do teens view the physical and social impact of asthma compared to other chronic diseases?
    Elaine Wirrell
    University of Calgary, AB, Canada
    J Asthma 43:155-60. 2006
  2. ncbi request reprint Epilepsy-related injuries
    Elaine C Wirrell
    Division of Neurology, Department of Pediatrics, Alberta Children s Hospital, Calgary, Alberta, Canada
    Epilepsia 47:79-86. 2006
  3. ncbi request reprint Do children with benign rolandic epilepsy have a higher prevalence of migraine than those with other partial epilepsies or nonepilepsy controls?
    Elaine C Wirrell
    Department of Pediatrics and Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Epilepsia 47:1674-81. 2006
  4. ncbi request reprint Neonatal seizures: to treat or not to treat?
    Elaine C Wirrell
    Division of Pediatric Neurology, Alberta Childrens Hospital, Calgary, Alberta, Canada
    Semin Pediatr Neurol 12:97-105. 2005
  5. doi request reprint Deterioration in cognitive function in children with benign epilepsy of childhood with central temporal spikes treated with sulthiame
    Elaine Wirrell
    Pediatrics and Clinical Neurosciences, University of Calgary, Alberta Children s Hospital, Calgary, Alberta, Canada
    J Child Neurol 23:14-21. 2008
  6. ncbi request reprint Sulthiame therapy for continuous spike and wave in slow-wave sleep
    Elaine Wirrell
    Department of Pediatrics, University of Calgary, Calgary, Canada
    Pediatr Neurol 35:204-8. 2006
  7. ncbi request reprint Autosomal recessive cerebellar hypoplasia in the Hutterite population
    Hannah C Glass
    Division of Neurology, Alberta Children s Hospital, Calgary, Alberta, Canada
    Dev Med Child Neurol 47:691-5. 2005
  8. ncbi request reprint Family function in cognitively normal children with epilepsy: impact on competence and problem behaviors
    Nancy Thornton
    Alberta Children s Hospital, Calgary, AB, Canada
    Epilepsy Behav 12:90-5. 2008
  9. ncbi request reprint Social skills problems in children with epilepsy: prevalence, nature and predictors
    Enrica Tse
    University of Alberta, Edmonton, Alberta, Canada
    Epilepsy Behav 11:499-505. 2007
  10. doi request reprint Depression, anxiety, and quality of life in siblings of children with intractable epilepsy
    Laura J Wood
    University of Alberta, Edmonton, AB, Canada
    Epilepsy Behav 13:144-8. 2008

Collaborators

Detail Information

Publications38

  1. ncbi request reprint How do teens view the physical and social impact of asthma compared to other chronic diseases?
    Elaine Wirrell
    University of Calgary, AB, Canada
    J Asthma 43:155-60. 2006
    ..Only 6 of 149 (4%) teens surveyed expressed any degree of reluctance to befriend peers with asthma...
  2. ncbi request reprint Epilepsy-related injuries
    Elaine C Wirrell
    Division of Neurology, Department of Pediatrics, Alberta Children s Hospital, Calgary, Alberta, Canada
    Epilepsia 47:79-86. 2006
    ..Appropriate vitamin D and calcium supplementation and periodic measurement of bone mineral density in those at risk for osteopenia are recommended...
  3. ncbi request reprint Do children with benign rolandic epilepsy have a higher prevalence of migraine than those with other partial epilepsies or nonepilepsy controls?
    Elaine C Wirrell
    Department of Pediatrics and Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Epilepsia 47:1674-81. 2006
    ..By using revised International Headache Society (IHS-R) criteria, we compared the prevalence of migraine in children with BREC with that of those (a) with cryptogenic/symptomatic partial epilepsy and (b) without epilepsy...
  4. ncbi request reprint Neonatal seizures: to treat or not to treat?
    Elaine C Wirrell
    Division of Pediatric Neurology, Alberta Childrens Hospital, Calgary, Alberta, Canada
    Semin Pediatr Neurol 12:97-105. 2005
    ..However, further work is needed to confirm the safety of excitatory amino acid antagonists in neonates because there remains a prevailing concern that such agents may impair normal neurodevelopmental processes...
  5. doi request reprint Deterioration in cognitive function in children with benign epilepsy of childhood with central temporal spikes treated with sulthiame
    Elaine Wirrell
    Pediatrics and Clinical Neurosciences, University of Calgary, Alberta Children s Hospital, Calgary, Alberta, Canada
    J Child Neurol 23:14-21. 2008
    ..Although sulthiame was effective at seizure control and significantly reduced spike frequency in children, it was also associated with deterioration in cognitive function...
  6. ncbi request reprint Sulthiame therapy for continuous spike and wave in slow-wave sleep
    Elaine Wirrell
    Department of Pediatrics, University of Calgary, Calgary, Canada
    Pediatr Neurol 35:204-8. 2006
    ..After 1 month of sulthiame therapy, his electroencephalographic abnormality had resolved, and his language development improved...
  7. ncbi request reprint Autosomal recessive cerebellar hypoplasia in the Hutterite population
    Hannah C Glass
    Division of Neurology, Alberta Children s Hospital, Calgary, Alberta, Canada
    Dev Med Child Neurol 47:691-5. 2005
    ..Neuroimaging is characterized by hypoplasia of the inferior portion of the cerebellar hemispheres and vermis, and mild simplification of cortical gyri...
  8. ncbi request reprint Family function in cognitively normal children with epilepsy: impact on competence and problem behaviors
    Nancy Thornton
    Alberta Children s Hospital, Calgary, AB, Canada
    Epilepsy Behav 12:90-5. 2008
    ..In those at the lowest level, approximately half of the children in either cohort had problems. For average functioning families, behavior and competence issues were more frequent in children with epilepsy than their siblings...
  9. ncbi request reprint Social skills problems in children with epilepsy: prevalence, nature and predictors
    Enrica Tse
    University of Alberta, Edmonton, Alberta, Canada
    Epilepsy Behav 11:499-505. 2007
    ..98) and abnormal family function (odds ratio=8.75, 95% CI=1.42-53.83) were strongly predictive of social skills impairment. Lower social skills were moderately correlated with epilepsy-specific and global quality of life (P<0.001)...
  10. doi request reprint Depression, anxiety, and quality of life in siblings of children with intractable epilepsy
    Laura J Wood
    University of Alberta, Edmonton, AB, Canada
    Epilepsy Behav 13:144-8. 2008
    ..We conclude that siblings of children with intractable epilepsy are functioning well overall and have a good quality of life...
  11. doi request reprint Perceived health in children presenting with a "first seizure"
    Lorie Hamiwka
    Alberta Children s Hospital, University of Calgary, Calgary, AB, Canada
    Epilepsy Behav 13:485-8. 2008
    ..It is important for physicians and health care providers to be aware of these concerns as they might impact further interventions...
  12. doi request reprint Feasibility and clinical utility of early electroencephalogram (EEG) in children with first seizure
    Lorie Hamiwka
    Alberta Children s Hospital, University of Calgary, Calgary, Alberta, Canada
    J Child Neurol 23:762-5. 2008
    ..Increased abnormalities were not seen with early electroencephalography (P = .50). Early electroencephalograms may not be feasible in the pediatric population and did not show a higher yield of abnormalities...
  13. ncbi request reprint The epileptic encephalopathies of infancy and childhood
    Elaine Wirrell
    Department of Pediatrics, University of Calgary, AB, Canada
    Can J Neurol Sci 32:409-18. 2005
    ..This paper will review the most common epileptic encephalopathy syndromes, discuss the cognitive and behavioral co-morbidities and review current therapeutic options...
  14. ncbi request reprint Management of intractable epilepsy in infancy and childhood
    Elaine Wirrell
    Pediatrics and Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Adv Neurol 97:463-91. 2006
  15. ncbi request reprint Diseases and syndromes associated with intractable epilepsy
    Sharon Whiting
    Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
    Adv Neurol 97:443-62. 2006
  16. ncbi request reprint Seizure-alerting and -response behaviors in dogs living with epileptic children
    Adam Kirton
    Division of Pediatric Neurology, Department of Pediatrics, Alberta Children s Hospital, Faculty of Medicine, University of Calgary, Alberta, Canada
    Neurology 62:2303-5. 2004
    ..Anticipation occurred early and was both sensitive and specific. Quality of life was higher in families with a dog that responded to seizures...
  17. ncbi request reprint Sleep disturbances in children with epilepsy compared with their nearest-aged siblings
    Elaine Wirrell
    Departments of Pediatrics and Neurosciences, University of Calgary, Alberta, Canada
    Dev Med Child Neurol 47:754-9. 2005
    ..We conclude that children with epilepsy in this current study had significantly greater sleep problems than their non-epileptic siblings...
  18. ncbi request reprint Use of complementary and alternative medical therapies in a pediatric neurology clinic
    Isaac Soo
    Faculty of Medicine, University of Alberta, Edmonton, AB, Canada
    Can J Neurol Sci 32:524-8. 2005
    ..Studies on CAM in neurological disorders have focused on the adult population and its use among pediatric neurology patients has not been well characterized...
  19. ncbi request reprint Micturition and emotion-induced reflex epilepsy: case report and review of the literature
    Hannah C Glass
    Division of Pediatric Neurology, Alberta Children s Hospital and Department of Pediatric Neurology, University of Calgary, Alberta, Canada
    Epilepsia 47:2180-2. 2006
  20. doi request reprint Health behavior in teens with epilepsy: how do they compare with controls?
    C G Yu
    University of Calgary, Calgary, AB, Canada
    Epilepsy Behav 13:90-5. 2008
    ....
  21. ncbi request reprint Sleep disturbance in children with migraine
    Kenneth Heng
    Department of Pediatrics and Clinical Neurosciences, University of Calgary, Alberta Children s Hospital, 1820 Richmond Road SW, Calgary, Alberta, Canada
    J Child Neurol 21:761-6. 2006
    ..006). We conclude that children with migraine are prone to greater sleep and behavioral disturbances than children without headache. Sleep disorders should be routinely queried and appropriate advice on sleep hygiene provided...
  22. ncbi request reprint Unique clinical phenomenology can help distinguish primary from secondary generalized seizures in children
    Adam Kirton
    Division of Pediatric Neurology, Department of Pediatrics, Alberta Children s Hospital, Faculty of Medicine, University of Calgary, Calgary, AB
    J Child Neurol 19:265-70. 2004
    ..The clinical features of a generalized convulsion in a child, especially mouth opening and late motor events, can be useful in establishing the origin as either focal or primary generalized...
  23. doi request reprint The incidence of injuries in persons with and without epilepsy--a population-based study
    Churl Su Kwon
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Epilepsia 51:2247-53. 2010
    ..To compare the 1-year population-based incidence and types of injuries in persons with and without epilepsy...
  24. ncbi request reprint Where do families of children with epilepsy obtain their information?
    Cathy Lu
    Department of Biological Sciences, University of Calgary, AB, Canada
    J Child Neurol 20:905-10. 2005
    ..Friends within the medical profession, other families, and complementary health care providers also ranked highly. Recommendation of sites and books by epilepsy clinics is more helpful than general handouts...
  25. ncbi request reprint The definition and prediction of intractable epilepsy in children
    Kevin Farrell
    Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada
    Adv Neurol 97:435-42. 2006
  26. ncbi request reprint A pediatric case of reversible segmental cerebral vasoconstriction
    Adam Kirton
    Department of Pediatrics, Division of Pediatric Neurology, Faculty of Medicine, University of Calgary, Calgary, AB, Canada
    Can J Neurol Sci 33:250-3. 2006
    ....
  27. ncbi request reprint Acute necrotizing encephalopathy in caucasian children: two cases and review of the literature
    Adam Kirton
    Division of Pediatric Neurology, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada
    J Child Neurol 20:527-32. 2005
    ..These cases are unique in their occurrence in non-Japanese children and are among the first published reports in Canada...
  28. pmc Homozygous deletion of the very low density lipoprotein receptor gene causes autosomal recessive cerebellar hypoplasia with cerebral gyral simplification
    Kym M Boycott
    Department of Medical Genetics, Alberta Children s Hospital and University of Calgary, Alberta, Canada
    Am J Hum Genet 77:477-83. 2005
    ..To our knowledge, this syndrome represents the first human lipoprotein receptor malformation syndrome and the second human disease associated with a reelin pathway defect...
  29. ncbi request reprint Stroke after varicella vaccination
    Elaine Wirrell
    Division of Pediatric Neurology, Alberta Children s Hospital, and the University of Calgary, Ontario, Canada
    J Pediatr 145:845-7. 2004
    ..Both children had small patent foramen ovale (PFO), and one child also had severe iron-deficiency anemia, which may have predisposed the patient to this adverse effect...
  30. doi request reprint Peri-ictal headache in children: prevalence and character
    Shayne Cai
    Department of Biomedical Sciences, University of Calgary, Calgary, Alberta, Canada
    Pediatr Neurol 39:91-6. 2008
    ..We conclude that peri-ictal headaches are common, affecting 41% of children with epilepsy. Their presence should be routinely queried, and if documented, treatment with simple analgesics appears beneficial and should be considered...
  31. ncbi request reprint Prolonged neonatal seizures exacerbate hypoxic-ischemic brain damage: correlation with cerebral energy metabolism and excitatory amino acid release
    Jerome Y Yager
    Department of Pediatrics, University of Saskatchewan, Saskatoon, Canada
    Dev Neurosci 24:367-81. 2002
    ....
  32. ncbi request reprint Valproic acid-associated weight gain in older children and teens with epilepsy
    Elaine C Wirrell
    Department of Pediatrics, Division of Neurology, University of Calgary, T2T 5C7, Calgary, AB, Canada
    Pediatr Neurol 28:126-9. 2003
    ..0002). Two factors tended to predict an increase in body mass index: normal neurocognitive status (P = 0.06) and primary generalized seizure type (P = 0.07)...
  33. ncbi request reprint Natural history of absence epilepsy in children
    Elaine C Wirrell
    Department of Pediatrics, University of Calgary, AB, Canada
    Can J Neurol Sci 30:184-8. 2003
    ..Psychosocial outcome is often poor, even in patients with more benign forms of absence epilepsy. Remission of epilepsy does not preclude psychosocial morbidity...
  34. ncbi request reprint Preventing hyperthermia decreases brain damage following neonatal hypoxic-ischemic seizures
    Jerome Y Yager
    Department of Pediatrics, University of Saskatchewan, 103 Hospital Drive, Saskatoon, Saskatchewan, Canada S7N 0W8
    Brain Res 1011:48-57. 2004
    ..05). The results indicate that preventing spontaneous hyperthermia in this model of hypoxic-ischemic seizures in the newborn is neuroprotective...
  35. doi request reprint Self-concept in adolescents with epilepsy: biological and social correlates
    Arden Lee
    Faculty of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 38:335-9. 2008
    ..We conclude that self-concept in teens with epilepsy is most strongly associated with Family Function. With the exception of current number of antiepileptic drugs used, epilepsy-specific factors are of minimal importance...
  36. doi request reprint Parenting stress in mothers of children with intractable epilepsy
    Elaine C Wirrell
    Division of Child and Adolescent Neurology, Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Epilepsy Behav 13:169-73. 2008
    ..The goal of the work described here was to determine the prevalence and characteristics of maternal stress in families of children with intractable epilepsy...
  37. ncbi request reprint De-novo mutations of the sodium channel gene SCN1A in alleged vaccine encephalopathy: a retrospective study
    Samuel F Berkovic
    Epilepsy Research Centre and Department of Medicine, University of Melbourne, Austin Health, Heidelberg West, Victoria, Australia
    Lancet Neurol 5:488-92. 2006
    ....
  38. ncbi request reprint Is a fast necessary when initiating the ketogenic diet?
    Elaine C Wirrell
    Division of Neurology, University of Calgary, Alberta Children s Hospital, Calgary, AB
    J Child Neurol 17:179-82. 2002
    ..The ketogenic diet can be effectively initiated without a fast in children with epilepsy. Time to ketosis and diet efficacy are similar to protocols that use a fast...