Research Topics
Genomes and GenesSpecies | Kumanan WilsonSummaryAffiliation: University of Toronto Country: Canada Publications
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Publications
Effectiveness of smoking cessation therapies: a systematic review and meta-analysisPing Wu
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
BMC Public Health 6:300. 2006..These include Nicotine Replacement Therapy [NRT], bupropion, and varenicline. We aimed to assess their relative efficacy in smoking cessation by conducting a systematic review and meta-analysis...
Teaching Evidence-Based Complementary and Alternative Medicine (EBCAM); changing behaviours in the face of reticence: a cross-over trialEdward Mills
Department of Research, The Canadian College of Naturopathic Medicine, North York, Canada
BMC Med Educ 2:2. 2002..In this study we attempt to determine if a workshop for final year students at a naturopathic college improved their ability to utilize critical appraisal concepts...
A policy analysis of major decisions relating to Creutzfeldt-Jakob disease and the blood supplyK Wilson
University of Ottawa Centre for Transfusion Research, Ottawa, Ont
CMAJ 165:59-65. 2001..We observed that the presence of a second operator had an important impact on decision-making in 1998/99...
Parental views on pediatric vaccination: the impact of competing advocacy coalitionsKumanan Wilson
Toronto General Hospital, Toronto, ON, Canada
Public Underst Sci 17:231-43. 2008..More research needs to be conducted to identify approaches to communicate the risks and benefits of vaccination to parents...
A survey of attitudes towards paediatric vaccinations amongst Canadian naturopathic studentsKumanan Wilson
Department of Medicine, University of Toronto, Toronto, Ont M5G 2C4, Canada
Vaccine 22:329-34. 2004....
The reporting of theoretical health risks by the media: Canadian newspaper reporting of potential blood transmission of Creutzfeldt-Jakob diseaseKumanan Wilson
Department of Medicine, University of Toronto, Toronto, Canada
BMC Public Health 4:1. 2004..In this article we describe how the Canadian print media reported the theoretical risk of blood transmission of Creutzfeldt-Jakob disease (CJD)...
A Canadian Agency for Public Health: could it work?Kumanan Wilson
Department of Medicine, University of Toronto, Toronto, Ont
CMAJ 170:222-3. 2004
Changing attitudes towards polio vaccination: a randomized trial of an evidence-based presentation versus a presentation from a polio survivorKumanan Wilson
Department of Medicine, University of Toronto, Canada
Vaccine 23:3010-5. 2005..These findings suggest that confronting deeply held beliefs regarding vaccination may paradoxically strengthen these belief systems...
Transfusion transmission of vCJD: a crisis avoided?Kumanan Wilson
Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
Lancet 364:477-9. 2004
The success of precaution? Managing the risk of transfusion transmission of variant Creutzfeldt-Jakob diseaseKumanan Wilson
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Transfusion 44:1475-8. 2004..These vCJD decisions serve as an example of the successful application of precaution and provide lesions as to how the principle should be applied in future transfusion safety decisions...
Strategies for implementing the new International Health Regulations in federal countriesKumanan Wilson
Department of Medicine, University of Toronto, Toronto, ON, Canada
Bull World Health Organ 86:215-20. 2008..We present here a series of recommendations, synthesized from the workshop proceedings, on strategies that these countries might pursue to improve their ability to comply with the revised IHR...
Characteristics of pediatric and adolescent patients attending a naturopathic college clinic in CanadaKumanan Wilson
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Pediatrics 115:e338-43. 2005..We also determined factors associated with the use of CAM products and vaccination status...
A third episode of transfusion-derived vCJDKumanan Wilson
Toronto General Hospital, University Health Network, Toronto, Ontario, Canada M5G 2C4
Lancet 368:2037-9. 2006
Variant Creutzfeldt-Jakob disease and the Canadian blood system after the tainted blood tragedyKumanan Wilson
University of Toronto, Toronto, Ont, Canada M5G 2C4
Soc Sci Med 64:174-85. 2007..The challenge the blood system now faces is to find the appropriate balance between maximizing safety and ensuring the system remains affordable...
Addressing the emergence of pediatric vaccination concerns: recommendations from a Canadian policy analysisKumanan Wilson
Department of Medicine, University of Toronto, Toronto, ON
Can J Public Health 97:139-41. 2006..However, such an investment is easy to justify given the benefits offered by pediatric vaccination and the ramifications of failing to maintain confidence in vaccination programs or missing a vaccine-related adverse event...
The challenge of an increasingly expensive blood systemKumanan Wilson
Department of Medicine, University of Toronto, Toronto, ON
CMAJ 168:1149-50. 2003
The Krever Commission--10 years laterKumanan Wilson
Department of Medicine, University of Toronto, Toronto, Ont
CMAJ 177:1387-9. 2007
The new International Health Regulations and the federalism dilemmaKumanan Wilson
Department of Medicine, University of Toronto, Toronto, Canada
PLoS Med 3:e1. 2006
The effectiveness of interventions to reduce physician's levels of inappropriate transfusion: what can be learned from a systematic review of the literatureKumanan Wilson
Department of Medicine, University of Toronto, Ontario, Canada
Transfusion 42:1224-9. 2002
Does a perception of increased blood safety mean increased blood transfusion? An assessment of the risk compensation theory in CanadaMo Amin
Department of Economics, University of Ottawa, 2 Saddle Crescent, Ottawa, ON, K1G 5L4, Canada
BMC Public Health 4:20. 2004..g., the appropriateness in transfusion). Further, it presents the findings of a pilot survey of physicians in Canada...
Teaching evidence-based complementary and alternative medicine: 2. A conceptual approach to causation-part 2Kumanan Wilson
Department of Medicine, University of Toronto, Ontario, Canada
J Altern Complement Med 8:385-9. 2002..more likely to lead to disease? Is there evidence from several different studies showing the same association? Does withdrawal of the cause result in loss of the effect? Is there a biologic model that can explain the causal relationship?..
Adverse events following 12 and 18 month vaccinations: a population-based, self-controlled case series analysisKumanan Wilson
Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Canada
PLoS ONE 6:e27897. 2011..Live vaccines have distinct safety profiles, potentially causing systemic reactions one to 2 weeks after administration. In the province of Ontario, Canada, live MMR vaccine is currently recommended at age 12 months and 18 months...
Protecting global health security through the International Health Regulations: requirements and challengesKumanan Wilson
Ottawa Health Research Institute, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
CMAJ 179:44-8. 2008
How should Canada fund the blood system? An evaluation of the chargeback proposalKumanan Wilson
Department of Medicine, University of Toronto, USA
Hosp Q 6:47-4. 2003..Based on a review of documents and stakeholder interviews, we report the potential advantages and disadvantages of a change to a new system of funding and make recommendations on how provinces should proceed...
The impact of severe acute respiratory syndrome on medical house staff: a qualitative studyGloria Rambaldini
Division of General Internal Medicine, University Health Network, Toronto, Ontario, Canada
J Gen Intern Med 20:381-5. 2005..It is hoped that training programs for health care professionals will be able to implement these tenets of crisis management as they develop strategies for dealing with future health threats...
Teaching evidence-based complementary and alternative medicine: 5. Interpreting the results of a study on therapy and applying them to a patientKumanan Wilson
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
J Altern Complement Med 8:867-73. 2002....
The effect of hospital-acquired infection with Clostridium difficile on length of stay in hospitalAlan J Forster
Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ont
CMAJ 184:37-42. 2012..We determined the independent impact of hospital-acquired infection with C. difficile on length of stay in hospital...
Adherence to HAART: a systematic review of developed and developing nation patient-reported barriers and facilitatorsEdward J Mills
Centre for International Health and Human Rights Studies, Toronto, Ontario, Canada
PLoS Med 3:e438. 2006..We systematically reviewed the literature to determine patient-reported barriers and facilitators to adhering to antiretroviral therapy...
The proportion of variation in perioperative transfusion decisions in Canada attributable to the hospitalNadine Shehata
Division of Hematology, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Can J Anaesth 54:902-7. 2007..The objective of this report was to quantify hospital variation in red cell transfusion decisions perioperatively for patients undergoing coronary artery bypass surgery (CABG)...
Emerging norms for the control of emerging epidemicsChristopher W McDougall
Joint Centre for Bioethics, University of Toronto, Toronto, ON, Canada
Bull World Health Organ 86:643-5. 2008
Teaching evidence-based complementary and alternative medicine: 4. Appraising the evidence for papers on therapyKumanan Wilson
Department of Medicine, University of Toronto, Ontario, Canada
J Altern Complement Med 8:673-9. 2002....
Vaccine-critical videos on YouTube and their impact on medical students' attitudes about seasonal influenza immunization: a pre and post studyPierre Robichaud
Dalla Lana School of Public Health, 155 College Street, Health Science Building, 6th Floor, Toronto, ON, Canada
Vaccine 30:3763-70. 2012..However, our study suggests that there is an opportunity for public health to leverage YouTube to communicate accurate and credible information regarding influenza to medical students and others...
The application of the precautionary principle to the blood system: the Canadian blood system's vCJD donor deferral policyKumanan Wilson
University of Ottawa Centre for Transfusion Research, Ottawa, Canada
Transfus Med Rev 17:89-94. 2003..This dilemma is somewhat unique to the public health sector and will likely recur in future applications of the principle to transfusion policy...
Vaccines in the public eyePaul Ritvo
School of Kinesiology and Health Sciences and Department of Psychology, York University, Toronto, Ontario M3J 1P3, Canada
Nat Med 11:S20-4. 2005..As a result, they have received much recent attention in the media that has exposed some of the challenges involved in optimally using vaccine technology...
The case for a vaccine injury compensation program for CanadaKumanan Wilson
Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON
Can J Public Health 103:122-4. 2012..This article outlines the arguments for a compensation program and the design elements that would be best suited to a program in the Canadian context...
Systematically reviewing qualitative studies complements survey design: an exploratory study of barriers to paediatric immunisationsEdward J Mills
Department of Clinical Epidemiology and Biostatistics, McMaster University, Health Science Centre, Hamilton, Ontario, Canada
J Clin Epidemiol 58:1101-8. 2005..We examined surveys addressing parental barriers to vaccinating children to determine if they comprehensively included themes identified in published qualitative studies...
Patterns of emergency room visits, admissions and death following recommended pediatric vaccinations - a population based study of 969,519 vaccination eventsKumanan Wilson
Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Canada
Vaccine 29:3746-52. 2011..The risk of immediate adverse events due to the inflammation created by a vaccine is a potential concern for pediatric vaccine programs...
Learning from Listeria: the autonomy of the Public Health Agency of CanadaKumanan Wilson
Department of Medicine, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ont
CMAJ 179:877-9. 2008
Factors affecting perioperative transfusion decisions in patients with coronary artery disease undergoing coronary artery bypass surgeryNadine Shehata
Division of Hematology, St Michael s Hospital, University of Toronto, Canada
Anesthesiology 105:19-27. 2006..The objectives of this study were to determine the hemoglobin concentration for transfusion and the factors that influence physicians' perioperative transfusion decisions for coronary artery bypass patients...
Closing comment: Evidence-based complementary and alternative medicine: is it a viable concept?Kumanan Wilson
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
J Altern Complement Med 8:875-6. 2002
The societal unit cost of allogenic red blood cells and red blood cell transfusion in CanadaMo Amin
Centre for Transfusion Research, University of Ottawa, Ottawa, Canada
Transfusion 44:1479-86. 2004..The unit cost of allogenic RBCs and RBC transfusion in Canada in 1994 was estimated at 152.17 US dollars. The objective of this study was to determine the unit cost of allogenic RBC transfusion in Canada from a societal perspective...
Vaccine and Immunization Surveillance in Ontario (VISION) - using linked health administrative databases to monitor vaccine safetyKumanan Wilson
Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Administrative Services Building, Room 1009, Box 684, Ottawa, ON K1Y 4E9, Canada
Vaccine 30:6115-20. 2012....
Impact of birth weight at term on rates of emergency room visits and hospital admissions following vaccination at 2 months of ageKumanan Wilson
Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Canada
Vaccine 29:8267-74. 2011..Birth weight of children born at term may theoretically be associated with risk of adverse events from immunization...
National immunization strategy. A model for resolving jurisdictional disputes in public healthJennifer Keelan
Dalla Lana School of Public Health, Faculty of Medicine, University of Toronto, Toronto, ON
Can J Public Health 99:376-9. 2008....
Strengthening the International Health Regulations: lessons from the H1N1 pandemicKumanan Wilson
Department of Medicine, Ottawa Health Research Institute, University of Ottawa, Canada
Health Policy Plan 25:505-9. 2010..Support for the IHR(2005) should be broadened and deepened to improve their utility as a tool to strengthen global health security...
The duty to care in a pandemicRoss Upshur
University of Toronto, Joint Centre for Bioethics, 88 College Street, Toronto, Ontario M5G1L4, Canada
Am J Bioeth 8:31-3. 2008
Teaching evidence-based complementary and alternative medicine: 3. Asking the questions and identifying the informationKumanan Wilson
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
J Altern Complement Med 8:499-506. 2002..This paper suggests practical strategies for successful database searches in support of EBCAM...
Reducing the amount of blood transfused: a systematic review of behavioral interventions to change physicians' transfusion practicesAlan Tinmouth
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
Arch Intern Med 165:845-52. 2005..Appropriately designed clinical trials are still needed to determine the relative effectiveness of different interventions to change practices...
Guillain-Barré syndrome after influenza vaccination in adults: a population-based studyDavid N Juurlink
Institute of Clinical Evaluative Sciences, Sunnybrook and Women's College Health Sciences Centre, Toronto, Ontario
Arch Intern Med 166:2217-21. 2006..CONCLUSION: Influenza vaccination is associated with a small but significantly increased risk for hospitalization because of GBS...
A flu by any other name: why the World Health Organization should adopt the World Meteorological Association's storm naming system as a model for naming emerging infectious diseasesRebecca Schein
School of Public Health, University of Toronto, Toronto, Ontario, Canada
J Health Commun 17:532-45. 2012....
Variability in the clinical management of fatty acid oxidation disorders: results of a survey of Canadian metabolic physiciansBeth K Potter
Department of Epidemiology and Community Medicine, University of Ottawa, 451 Smyth Rd, Ottawa, Ontario, Canada
J Inherit Metab Dis 35:115-23. 2012..While consensus guidelines are important, understanding areas where there is a lack of consensus is also critical to inform priorities for future evaluative research...
The challenges in making electronic health records accessible to patientsLeslie Beard
Centre for Innovation in Complex Care, University Health Network, Toronto, Canada
J Am Med Inform Assoc 19:116-20. 2012....
ABO-identical versus nonidentical platelet transfusion: a systematic reviewNadine Shehata
Department of Medicine, University of Toronto, Division of Hematology, St Michael s Hospital, Toronto, Ontario, Canada
Transfusion 49:2442-53. 2009..The primary objective of this report is to assess whether ABO-identical PLT transfusion is associated with improved mortality and/or morbidity for patients with hematologic/oncologic disorders...
Revisiting the possibility of serious adverse events from the whole cell pertussis vaccine: were metabolically vulnerable children at risk?Kumanan Wilson
Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Canada
Med Hypotheses 74:150-4. 2010..Nevertheless, at a population level, enough events could have occurred to cause concern amongst parents...
Association of autistic spectrum disorder and the measles, mumps, and rubella vaccine: a systematic review of current epidemiological evidenceKumanan Wilson
Department of Medicine and Health Policy, University of Toronto, Ontario, Canada
Arch Pediatr Adolesc Med 157:628-34. 2003..Given the real risks of not vaccinating and that the risks and existence of variant ASD remain theoretical, current policies should continue to advocate the use of the MMR vaccine...
The responsibility of healthcare institutions to protect global health securityKumanan Wilson
Ottawa Health Research Institute, Department of Medicine, University of Ottawa, Ottawa, Ontario
Healthc Q 12:56-60, 2. 2009..This unanimously approved document outlines how countries are to prepare for and respond to public health emergencies of international concern in a manner that does not unnecessarily impact on travel and trade...
A Canadian framework for applying the precautionary principle to public health issuesErica Weir
Division of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, ON
Can J Public Health 101:396-8. 2010....
Public health through a different lensRaisa Deber
Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Toronto, ON
Healthc Pap 7:66-71. 2007..Public health is heterogeneous, and many roads may lead us to the promised land...
The complexities of multi-level governance in public healthKumanan Wilson
Department of Medicine, University of Toronto, Toronto, ON
Can J Public Health 95:409-12. 2004..To do so, policy-makers need to address unique challenges to public health governance...
Health food store recommendations: implications for breast cancer patientsEdward Mills
Department of Research, Canadian College of Naturopathic Medicine, North York, Ontario, Canada
Breast Cancer Res 5:R170-4. 2003..Many breast cancer patients use complementary and alternative medicine (CAM). We aimed to determine what advice health food store employees present to individuals seeking treatment options for breast cancer...
Parents' experiences discussing pediatric vaccination with healthcare providers: a survey of Canadian naturopathic patientsJason W Busse
Institute for Work and Health, Toronto, Ontario, Canada
PLoS ONE 6:e22737. 2011..Groups that are associated with reduced rates of pedicatic vaccination, such as parents who access naturopathic care, may be particularly vulnerable to this issue...
Teaching evidence-based complementary and alternative medicine: 2. A conceptual approach to causation-part 1Kumanan Wilson
Department of Medicine, University of Toronto, Ontario, Canada
J Altern Complement Med 8:379-83. 2002....
The first three years of screening for medium chain acyl-CoA dehydrogenase deficiency (MCADD) by newborn screening ontarioShelley Kennedy
Newborn Screening Ontario, Children s Hospital of Eastern Ontario, Ottawa, Ontario, Canada
BMC Pediatr 10:82. 2010..This study reports on the first three years of newborn screening for MCADD in Ontario, Canada...
An analysis of the Human Papilloma Virus vaccine debate on MySpace blogsJennifer Keelan
Dalla Lana School of Public Health, University of Toronto, Canada
Vaccine 28:1535-40. 2010..We tracked the debate in the United States through MySpace, then the most popular social networking site, in order to better understand the public's reaction to the vaccine...
Use of intravenous immunoglobulin for treatment of neurologic conditions: a systematic reviewDean Fergusson
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Ontario, Canada
Transfusion 45:1640-57. 2005....
Balancing vaccine science and national policy objectives: lessons from the National Vaccine Injury Compensation Program Omnibus Autism ProceedingsJennifer Keelan
Dalla Lana School of Public Health, University of Toronto, Ontario, Canada
Am J Public Health 101:2016-21. 2011..In fact, the courts have functioned as intended and have allowed for a fair hearing of vaccine concerns while maintaining confidence in vaccines and providing protection to vaccine manufacturers...
Severe acute respiratory syndrome and its impact on professionalism: qualitative study of physicians' behaviour during an emerging healthcare crisisSharon E Straus
Division of General Internal Medicine, University Health Network, 200 Elizabeth Street, Toronto, ON, Canada M5G 2C4
BMJ 329:83. 2004..To explore issues of medical professionalism in the context of severe acute respiratory syndrome (SARS), a new emerging health threat...
Preserving relationships with antivaccine parents: five suggestions from social psychologyJennifer Fortune
Toronto General Hospital, 200 Elizabeth St, Toronto, ON, Canada
Can Fam Physician 53:2083-5, 2093-5. 2007
A framework for applying the precautionary principle to transfusion safetyKumanan Wilson
Department of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada
Transfus Med Rev 25:177-83. 2011....
Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta-analysisEdward Mills
Faculty of Health Sciences, Clinical Epidemiology and Biostatistics, McMaster University, HSC 2C12, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada
Eur J Clin Pharmacol 61:1-7. 2005..To determine whether ingestion of milk thistle affects the pharmacokinetics of indinavir...
Barriers to participating in an HIV vaccine trial: a systematic reviewEdward Mills
AIDS 18:2235-42. 2004
Consensus conference on vCJD screening of blood donors: report of the panelJeffrey McCullough
University of Minnesota, Minneapolis, Minnesota 55455, USA
Transfusion 44:675-83. 2004
Protecting vaccine programs and the publicKumanan Wilson
CMAJ 176:1681, 1683. 2007
WHO's response to global public health threats: XDR-TBKumanan Wilson
PLoS Med 4:e246. 2007
Teaching evidence-based complementary and alternative medicine: 1. A learning structure for clinical decision changesEdward J Mills
Department of Research, The Canadian College of Naturopathic Medicine, North York, Ontario
J Altern Complement Med 8:207-14. 2002..In order to create communication effectively, an evidence-based approach may provide the common ground required for all schools of thought...
Introducing evidence-based complementary and alternative medicine: answering the challengeKumanan Wilson
J Altern Complement Med 8:103-5. 2002
Emerging issues associated with HIV patients seeking advice from health food storesEdward Mills
Dept of Research, Canadian College of Naturopathic Medicine, North York, ON
Can J Public Health 94:363-6. 2003..To ascertain the recommendations, training and education of health food store employees and determine how they communicate the costs, benefits and risks associated with natural health products for the HIV/AIDS community...
YouTube as a source of information on immunization: a content analysisJennifer Keelan
JAMA 298:2482-4. 2007
Systematic review of qualitative studies exploring parental beliefs and attitudes toward childhood vaccination identifies common barriers to vaccinationEdward Mills
University of Oxford, UK
J Clin Epidemiol 58:1081-8. 2005..CONCLUSION: Systematically reviewing qualitative studies on barriers to childhood vaccination provided important information on barriers that are consistently identified by parents in several different studies...
A new human genotype prone to variant Creutzfeldt-Jakob diseaseKumanan Wilson
BMJ 332:1164-5. 2006
