Hao Wang

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. doi Small animal models of xenotransplantation
    Hao Wang
    Department of General Surgery, Tianjin Medical University General Hospital, Tianjin General Surgery Institute, Tianjin, China
    Methods Mol Biol 885:125-53. 2012
  2. pmc Allogeneic endometrial regenerative cells: an "Off the shelf solution" for critical limb ischemia?
    Michael P Murphy
    Division of Vascular Surgery, Indiana University School of Medicine, Indiana, USA
    J Transl Med 6:45. 2008
  3. pmc Feasibility investigation of allogeneic endometrial regenerative cells
    Zhaohui Zhong
    Medistem Inc, San Diego, USA
    J Transl Med 7:15. 2009
  4. pmc Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis
    Neil H Riordan
    Medistem Inc, San Diego, CA, USA
    J Transl Med 7:29. 2009
  5. pmc Endometrial regenerative cells: a novel stem cell population
    Xiaolong Meng
    Bio Communications Research Institute, Wichita, USA
    J Transl Med 5:57. 2007
  6. ncbi Inhibition of terminal complement components in presensitized transplant recipients prevents antibody-mediated rejection leading to long-term graft survival and accommodation
    Hao Wang
    Multi Organ Transplant Program, University Hospital, London Health Sciences Centre, London, Ontario, Canada
    J Immunol 179:4451-63. 2007
  7. doi Free bone graft attenuates acute rejection and in combination with cyclosporin a leads to indefinite cardiac allograft survival
    Hao Wang
    Multi Organ Transplant Program, University Hospital, Lawson Health Research Institute, London Health Sciences Centre, London, Ontario, Canada
    J Immunol 182:5970-81. 2009
  8. doi Prolongation of cardiac allograft survival by rapamycin and the invariant natural killer T cell glycolipid agonist OCH
    S M Mansour Haeryfar
    Department of Microbiology and Immunology, The University of Western Ontario, London, Ontario, Canada
    Transplantation 86:460-8. 2008
  9. ncbi Regulation of B- and T-cell mediated xenogeneic transplant rejection by interleukin 12
    Karoline A Hosiawa
    Division of Experimental Therapeutics, University Health Network, Toronto General Research Institute, Toronto, Ontario, Canada
    Transplantation 81:265-72. 2006
  10. ncbi Distinct subsets of dendritic cells regulate the pattern of acute xenograft rejection and susceptibility to cyclosporine therapy
    Hao Wang
    Multi Organ Transplant Program, London Health Sciences Centre University Hospital, 339 Windermere Road, London, Ontario, Canada N6A 5A5
    J Immunol 176:3525-35. 2006

Collaborators

Detail Information

Publications66

  1. doi Small animal models of xenotransplantation
    Hao Wang
    Department of General Surgery, Tianjin Medical University General Hospital, Tianjin General Surgery Institute, Tianjin, China
    Methods Mol Biol 885:125-53. 2012
    ..The methodology for the small animal model establishment includes animal selection, preoperative care, anesthesia, postoperative care, and detailed procedures...
  2. pmc Allogeneic endometrial regenerative cells: an "Off the shelf solution" for critical limb ischemia?
    Michael P Murphy
    Division of Vascular Surgery, Indiana University School of Medicine, Indiana, USA
    J Transl Med 6:45. 2008
    ....
  3. pmc Feasibility investigation of allogeneic endometrial regenerative cells
    Zhaohui Zhong
    Medistem Inc, San Diego, USA
    J Transl Med 7:15. 2009
    ..These preliminary data suggest feasibility of clinical ERC administration and support further studies with this novel stem cell type...
  4. pmc Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis
    Neil H Riordan
    Medistem Inc, San Diego, CA, USA
    J Transl Med 7:29. 2009
    ..Based on this rationale and initial experiences, we propose controlled trials of autologous SVF in various inflammatory conditions...
  5. pmc Endometrial regenerative cells: a novel stem cell population
    Xiaolong Meng
    Bio Communications Research Institute, Wichita, USA
    J Transl Med 5:57. 2007
    ..Given the ease of extraction and pluripotency of this cell population, we propose ERC as a novel alternative to current stem cells sources...
  6. ncbi Inhibition of terminal complement components in presensitized transplant recipients prevents antibody-mediated rejection leading to long-term graft survival and accommodation
    Hao Wang
    Multi Organ Transplant Program, University Hospital, London Health Sciences Centre, London, Ontario, Canada
    J Immunol 179:4451-63. 2007
    ..These data suggest that terminal complement blockade with a functionally blocking Ab represents a promising therapeutic approach to prevent AMR in presensitized recipients...
  7. doi Free bone graft attenuates acute rejection and in combination with cyclosporin a leads to indefinite cardiac allograft survival
    Hao Wang
    Multi Organ Transplant Program, University Hospital, Lawson Health Research Institute, London Health Sciences Centre, London, Ontario, Canada
    J Immunol 182:5970-81. 2009
    ..Due to the fact that current immunosuppressive approaches are clinically ineffective at preventing AVR, this study provides promise for further investigations of BM components as a means of addressing a currently unmet medical need...
  8. doi Prolongation of cardiac allograft survival by rapamycin and the invariant natural killer T cell glycolipid agonist OCH
    S M Mansour Haeryfar
    Department of Microbiology and Immunology, The University of Western Ontario, London, Ontario, Canada
    Transplantation 86:460-8. 2008
    ..Although iNKT cells have been implicated in cardiac allograft tolerance, whether in vivo triggering of iNKT cells with Th2-promoting glycolipids offers a therapeutic benefit in heart transplantation remains unexplored...
  9. ncbi Regulation of B- and T-cell mediated xenogeneic transplant rejection by interleukin 12
    Karoline A Hosiawa
    Division of Experimental Therapeutics, University Health Network, Toronto General Research Institute, Toronto, Ontario, Canada
    Transplantation 81:265-72. 2006
    ..In animal models where acute vascular rejection can be attenuated, xenografts succumb to cell-mediated rejection. The mechanisms of acute vascular rejection and cell-mediated rejection are poorly understood...
  10. ncbi Distinct subsets of dendritic cells regulate the pattern of acute xenograft rejection and susceptibility to cyclosporine therapy
    Hao Wang
    Multi Organ Transplant Program, London Health Sciences Centre University Hospital, 339 Windermere Road, London, Ontario, Canada N6A 5A5
    J Immunol 176:3525-35. 2006
    ..Our data suggest that the pattern of acute xenogeneic rejection can be regulated by distinct DC subsets...
  11. ncbi Long-term limb allograft survival using a short course of anti-CD45RB monoclonal antibody, LF 15-0195, and rapamycin in a mouse model
    Toni Zhong
    Division of Plastic Surgery, Department of Surgery, The University of Western Ontario, London, Ontario, Canada
    Transplantation 84:1636-43. 2007
    ..The purpose of this study was to determine if a short course of monoclonal antibody (mAb) against CD45RB, LF 15-0195, and rapamycin would achieve long-term survival by inducing tolerance in a mouse limb transplant model...
  12. doi Immunosuppression involving soluble CD83 induces tolerogenic dendritic cells that prevent cardiac allograft rejection
    Wei Ge
    Department of Surgery, University of Western Ontario, London, ON, Canada
    Transplantation 90:1145-56. 2010
    ..Dendritic cells (DCs) are crucial regulators of immunity and important in inducing and maintaining tolerance. Here, we investigated the potential of a novel DC-immunomodulating agent, soluble CD83 (sCD83), in inducing transplant tolerance...
  13. ncbi CD80/CD86 costimulation regulates acute vascular rejection
    Karoline A Hosiawa
    Division of Experimental Therapeutics, University Health Network, Toronto General Research Institute, Toronto General Hospital, Toronto, Ontario, Canada
    J Immunol 175:6197-204. 2005
    ..Most strikingly, indefinite xenograft survival can be achieved by suppressing AVR with CD86 neutralization in combination of CsA therapy, which inhibits CMR...
  14. ncbi Cytokines regulate the pattern of rejection and susceptibility to cyclosporine therapy in different mouse recipient strains after cardiac allografting
    Hao Wang
    Multi Organ Transplant Program, London Health Sciences Centre, London, Ontario, Canada
    J Immunol 171:3823-36. 2003
    ..These data suggest that the distinct cytokine profiles expressed by different mouse strains play an essential role in regulating the pattern of rejection and outcome of CsA/rapamycin therapy...
  15. doi Prevention of chronic renal allograft rejection by soluble CD83
    Zhu Lan
    Department of Surgery, University of Western Ontario, London, ON, Canada
    Transplantation 90:1278-85. 2010
    ..Our current research focus turned to examining the effects of peritransplant soluble CD83 (sCD83) administration on prevention of chronic renal allograft rejection...
  16. doi Induction of kidney allograft tolerance by soluble CD83 associated with prevalence of tolerogenic dendritic cells and indoleamine 2,3-dioxygenase
    Zhu Lan
    Department of Surgery, University of Western Ontario, London, ON, Canada
    Transplantation 90:1286-93. 2010
    ....
  17. ncbi Treatment with a short course of LF 15-0195 and continuous cyclosporin A attenuates acute xenograft rejection in a rat-to-mouse cardiac transplantation model
    Hao Wang
    The Multi Organ Transplant Program, London Health Sciences Center University Campus, 339 Windermere Road, London, Ontario N6A 5A5, Canada
    Xenotransplantation 10:325-36. 2003
    ..Also, treatment with short course LF 15-0195 and continuous CsA significantly reduced T-cell infiltration. Studies to test this therapy in inhibiting AVR in a pig-to-non-human primate xenotransplantation model are underway...
  18. ncbi Prevention of chronic renal allograft rejection by SERP-1 protein
    Eric L R Bédard
    Multiorgan Transplant Program, London Health Sciences Centre, University Campus, 339 Windermere Road, London, Ontario N6A 5A5, Canada
    Transplantation 81:908-14. 2006
    ..Here we examined the effect of peritransplant Serp-1 administration on chronic renal allograft rejection...
  19. doi Development of techniques for gastrojejunal bypass surgery in obese mice
    Zhu Lan
    Department of Surgery, The University of Western Ontario, London, ON, Canada
    Microsurgery 30:289-95. 2010
    ..This newly developed GJB surgery in the obese mice offers a unique advantage to study the mechanisms of gastrointestinal surgery as treatment for type 2 diabetes...
  20. ncbi Prevention of acute vascular rejection by a functionally blocking anti-C5 monoclonal antibody combined with cyclosporine
    Hao Wang
    Multi Organ Transplant Program, London Health Sciences Centre, London, Ontario, Canada
    Transplantation 79:1121-7. 2005
    ....
  21. ncbi Double-negative T cells, activated by xenoantigen, lyse autologous B and T cells using a perforin/granzyme-dependent, Fas-Fas ligand-independent pathway
    Zhu Xu Zhang
    Department of Surgery, University of Western Ontario, London, Ontario, Canada
    J Immunol 177:6920-9. 2006
    ..In conclusion, this study suggests that xenoreactive DNT cells can control B and T cell responses in perforin/granzyme-dependent mechanisms. DNT cells may be valuable in controlling B and T cell responses in xenotransplantation...
  22. ncbi Peritransplant treatment with cobalt protoporphyrin attenuates chronic renal allograft rejection
    Eric L R Bédard
    The Department of Surgery, The University of Western Ontario, London, Ontario, Canada
    Transpl Int 18:341-9. 2005
    ..012). In summary, the peritransplant up-regulation of HO-1 in renal allograft recipients significantly attenuates chronic rejection in rat renal allografts by inhibiting transplant vasculopathy...
  23. ncbi Induction of indefinite cardiac allograft survival correlates with toll-like receptor 2 and 4 downregulation after serine protease inhibitor-1 (Serp-1) treatment
    Jifu Jiang
    Multi Organ Transplant Program, London Health Sciences Centre University Hospital, London, Ontario, Canada
    Transplantation 84:1158-67. 2007
    ....
  24. ncbi Th1/Th2 xenogenic antibody responses are associated with recipient dendritic cells
    Nobuyuki Kanai
    Robarts Research Institute, London, ON, Canada
    Microsurgery 27:234-9. 2007
    ..Our findings suggest that DC could play an important role to regulate the balance of Th1/Th2 cytokine profiles and rejection patterns in xenotransplantation...
  25. doi Reduction of Foxp3-expressing regulatory T cell infiltrates during the progression of renal allograft rejection in a mouse model
    Shuang Wang
    Department of Medicine, The University of Western Ontario, London, ON, Canada
    Transpl Immunol 19:93-102. 2008
    ..However, Treg cell development and action are poorly understood in transplantation. In this study, the association of CD4(+)Foxp3(+) infiltrates within renal allograft tissue with graft survival was investigated in a mouse model...
  26. doi Carbon monoxide-releasing molecules protect against ischemia-reperfusion injury during kidney transplantation
    Yves Caumartin
    Department of Surgery, University of Western Ontario, London, Ontario, Canada
    Kidney Int 79:1080-9. 2011
    ..Thus, CORM-2-derived CO protects renal transplants from IRI by modulating inflammation...
  27. pmc Inhibition of chemokine-glycosaminoglycan interactions in donor tissue reduces mouse allograft vasculopathy and transplant rejection
    Erbin Dai
    Vascular Biology Research Group, Robarts Research Institute, The University of Western Ontario, London, Ontario, Canada
    PLoS ONE 5:e10510. 2010
    ..Here we examine the impact of interrupting chemokine-GAG interactions and chemokine-receptor interactions, both locally and systemically, on vascular disease in allografts...
  28. doi Prolonged renal allograft survival by donor interleukin-6 deficiency: association with decreased alloantibodies and increased intragraft T regulatory cells
    Hao Wang
    Department of Surgery, The University of Western Ontario, London, Ontario
    Am J Physiol Renal Physiol 302:F276-83. 2012
    ....
  29. doi Regulatory T-cell generation and kidney allograft tolerance induced by mesenchymal stem cells associated with indoleamine 2,3-dioxygenase expression
    Wei Ge
    Department of Surgery, University of Western Ontario, London, ON, Canada
    Transplantation 90:1312-20. 2010
    ..This study was designed to address whether MSCs induce kidney allograft tolerance and whether IDO contributes to the immunoregulatory functions of MSCs in vivo...
  30. doi Establishment of duodenojejunal bypass surgery in mice: a model designed for diabetic research
    Wei Liu
    Multi Organ Transplant Program, London Health Sciences Center, London, ON, Canada
    Microsurgery 28:197-202. 2008
    ..The intestinal mucosa showed normal histology and function. This study confirms that it is technically possible to perform DJB surgery in mice. This mouse model can be used in the study of surgical treatment for type II diabetes...
  31. doi Tumor necrosis factor-alpha preconditioning attenuates liver ischemia/reperfusion injury through preserving sarco/endoplasmic reticulum calcium-ATPase function
    Min Feng
    Department of General Surgery, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing, China
    J Surg Res 184:1109-13. 2013
    ..Tumor necrosis factor-alpha (TNF-α) is a multifunctional cytokine. In this study, we investigated the role of TNF-α preconditioning in liver ischemia/reperfusion injury (IRI)...
  32. ncbi Chemokine-binding viral protein M-T7 prevents chronic rejection in rat renal allografts
    Eric L R Bédard
    The Department of Surgery, The University of Western Ontario, London, Ontario, Canada
    Transplantation 76:249-52. 2003
    ..These data demonstrate for the first time that the immunoregulatory viral protein M-T7 can effectively attenuate chronic rejection in rat renal allografts...
  33. pmc Deficiency of Capn4 gene inhibits nuclear factor-κB (NF-κB) protein signaling/inflammation and reduces remodeling after myocardial infarction
    Jian Ma
    Critical Illness Research, Lawson Health Research Institute, University of Western Ontario, London, Ontario N6A 4G5, Canada
    J Biol Chem 287:27480-9. 2012
    ..These effects of Capn4 deletion may be mediated through prevention of IκB degradation and NF-κB activation, resulting in inhibition of inflammatory responses...
  34. ncbi Attenuation of acute xenograft rejection by short-term treatment with LF15-0195 and monoclonal antibody against CD45RB in a rat-to-mouse cardiac transplantation model
    Hao Wang
    Multi Organ Transplant Program, London Health Sciences Centre, Ontario, Canada
    Transplantation 75:1475-81. 2003
    ....
  35. doi Adoptive transfer of hepatic stellate cells ameliorates liver ischemia reperfusion injury through enriching regulatory T cells
    Min Feng
    Department of General Surgery, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China
    Int Immunopharmacol 19:267-74. 2014
    ..These nTregs also attenuated liver IRI partially. Depletion of Tregs abolished the protective effect of HSCs. Thus, we conclude that adoptive transferred HSCs ameliorate liver IRI in Tregs-dependent manner. ..
  36. doi Neuronal nitric oxide synthase protects against myocardial infarction-induced ventricular arrhythmia and mortality in mice
    Dylan E Burger
    Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada N6A5C1
    Circulation 120:1345-54. 2009
    ..However, the role of nNOS in cardiac electrophysiology after myocardial infarction (MI) is unclear. We hypothesized that nNOS deficiency increases ventricular arrhythmia and mortality after MI...
  37. doi Memory T Cells Mediate Cardiac Allograft Vasculopathy and are Inactivated by Anti-OX40L Monoclonal Antibody
    Hao Wang
    Department of General Surgery, Tianjin Medical University General Hospital, Tianjin General Surgery Institute, Tianjin, China
    Cardiovasc Drugs Ther 28:115-22. 2014
    ..This study investigated the role of Tmem cells in the development of CAV and the therapeutic potential of targeting the OX40/OX40L pathway for heart transplant survival...
  38. doi Ectopic Ikaros expression positively correlates with lung cancer progression
    Zhenfa Zhang
    Department of Lung Cancer, Lung Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin, 300060, China
    Anat Rec (Hoboken) 296:907-13. 2013
    ..Our results thus shed light on how Ikaros can act as a lineage competency factor to facilitate lung cancer progression...
  39. doi Matrix metalloprotease 9 promotes liver recovery from ischemia and reperfusion injury
    Min Feng
    Department of General Surgery, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing, China
    J Surg Res 180:156-61. 2013
    ..In this study, we investigated the role of MMP-9 in liver wound healing from ischemia and reperfusion injury (IRI)...
  40. doi Choosing hamsters but not rats as a model for studying plasma cholesterol-lowering activity of functional foods
    Zesheng Zhang
    Key Laboratory of Food Nutrition and Safety, Ministry of Education, Tianjin University of Science and Technology, Tianjin, China
    Mol Nutr Food Res 53:921-30. 2009
    ....
  41. ncbi [Analysis of risk factors associated with metastasis of lymph node along superior mesenteric vein in patients with gastric cancer]
    Ruohua Chen
    Department of General Surgery, Gulou Hospital, Nanjing University School of Medicine, Nanjing 210009, China
    Zhonghua Wei Chang Wai Ke Za Zhi 17:155-7. 2014
    ..To investigate the risk factors associated with metastasis of lymph node along superior mesenteric vein (No.14v) in gastric cancer...
  42. ncbi Glutamine supplemented parenteral nutrition prevents intestinal ischemia- reperfusion injury in rats
    Guo Hao Wu
    Department of General Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China
    World J Gastroenterol 10:2592-4. 2004
    ..To examine whether glutamine prevents the injury to the intestinal mucosa after intestinal ischemia-reperfusion (I/R) in rats...
  43. doi Reduction of chronic allograft nephropathy by inhibition of extracellular signal-regulated kinase 1 and 2 signaling
    Shuang Wang
    Department of Urologic Sciences, University of British Columbia, Jack Bell Research Centre, 2660 Oak Street, Vancouver, BC, Canada
    Am J Physiol Renal Physiol 295:F672-9. 2008
    ..Our data suggest that interference of MEK-ERK1/2 signaling with a pharmacological agent (e.g., CI-1040) has therapeutic potential to prevent CAN in kidney transplantation...
  44. ncbi [Clinical and histological features of the patients with hepatitis B recurrence after allo-genetic hemopoietic stem cell transplantation]
    Jie Shao
    Peking University People s Hospital, Peking University Hepatology Institute, Beijing 100044, China
    Zhonghua Gan Zang Bing Za Zhi 12:434-5. 2004
  45. ncbi Do younger female breast cancer patients have a poorer prognosis? Results from a population-based survival analysis
    Kee Seng Chia
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore
    Int J Cancer 108:761-5. 2004
    ..In patients with distant metastases, those younger than 35 years of age had the lowest excess risk of death. At the population level, younger women (< 45 years) with breast cancer in Singapore have higher relative survival rates...
  46. ncbi Short-term study of retinal pigment epithelium sheet transplants onto Bruch's membrane
    Hao Wang
    Department of Ophthalmology, Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 90 Bergen Street, 6th Floor, Newark, NJ 07101 1709, USA
    Exp Eye Res 78:53-65. 2004
    ..The survival and effectiveness of retinal pigment epithelium sheet transplants appeared similar to the retinal pigment epithelium microaggregates transplants conducted previously in this model...
  47. ncbi Restriction of third-generation cephalosporin use decreases infection-related mortality
    Bin Du
    Department of Critical Care Medicine, Peking Union Medical College Hospital, Beijing, People s Republic of China
    Crit Care Med 31:1088-93. 2003
    ..To determine the effect of restriction of third-generation cephalosporin use on antibiotic resistance and the outcome of patients with infection...
  48. doi Crystal structure of chimeric antibody C2H7 Fab in complex with a CD20 peptide
    Jiamu Du
    State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China
    Mol Immunol 45:2861-8. 2008
    ..Our data not only reveal the molecular basis for the fine specificity of C2H7 to CD20, but also provide valuable information for further improvement of antibodies derived from 2H7...
  49. ncbi [The prospective study of the clinical features and outcome of HBeAg-negative and HBeAg-positive cirrhosis in patients with chronic type B hepatitis]
    Hui Ma
    Hepatology Institute, Peking University People s Hospital, Beijing 100044, China
    Zhonghua Yi Xue Za Zhi 87:1832-5. 2007
    ..Comparing clinical features and prognosis between HBeAg-negative and HBeAg-positive cirrhosis in patients with chronic type B hepatitis...
  50. ncbi The role of chemokines and chemokine receptors in alloantigen-independent and alloantigen-dependent transplantation injury
    Mark E DeVries
    Department of Immunology, Division of Experimental Therapeutics, University of Toronto, University Health Network, 200 Elizabeth Street, Toronto, Ontario, Canada M5G 2C4
    Semin Immunol 15:33-48. 2003
    ..This review focuses on recent studies demonstrating the role of chemokines in transplantation...
  51. doi Neuroprotection of muscarinic receptor agonist pilocarpine against glutamate-induced apoptosis in retinal neurons
    Wei Zhou
    Department of Pharmacology, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, 200025, China
    Cell Mol Neurobiol 28:263-75. 2008
    ..The results may provide an insight into the new mechanism of glaucoma therapy that pilocarpine may potentially act as a retinal neuroprotectant...
  52. ncbi Monoclonal antibody against beta7 integrins, but not beta7 deficiency, attenuates intestinal allograft rejection in mice
    Richard Kellersmann
    Department of Surgery, University of Wurzburg, Wurzburg, Germany
    Transplantation 74:1327-34. 2002
    ..In the present study, we investigated the expression of beta7 integrins after small bowel transplantation (SBT) and tested the effects of blocking beta7-mediated pathways by using monoclonal antibody (mAb) or knockout mice...
  53. ncbi [Study in functional compensation of skin flap:an experimental of fast prefabricated random skin flap]
    Jun Xu
    Beijing Ji Shui Tan Hospital, Beijing 100035, China
    Zhonghua Wai Ke Za Zhi 42:692-4. 2004
    ..To investigate the possibility and the limit in increasing the survival area of the random skin flap by extremely increasing the ratio of its length and width within 24 hours...
  54. ncbi Phase II study of paclitaxel and estramustine in patients with recurrent and refractory non-Hodgkin lymphoma
    Hossein Borghaei
    Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
    Cancer 101:2034-41. 2004
    ....
  55. ncbi Complete response to neoadjuvant chemoradiotherapy in esophageal carcinoma is associated with significantly improved survival
    Adam C Berger
    Department of Surgical Oncology, and Division of Biostatistics, Fox Chase Cancer Center, 333 Cottman Ave, Philadelphia, PA 19111, USA
    J Clin Oncol 23:4330-7. 2005
    ..A large single-center experience was reviewed to determine which treatment-related variables could predict survival and recurrence...
  56. ncbi Open-chest device closure for the minimally invasive management of atrial septal defect in young children
    Hao Zhang
    Center for Pediatric Surgery, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Heart Surg Forum 10:E125-8. 2007
    ..We integrated a catheter-based device and minimally invasive surgical techniques for the treatment of atrial septal defect for children younger than 2 years old...
  57. ncbi Registry and survival study in chinese patients with idiopathic and familial pulmonary arterial hypertension
    Zhi Cheng Jing
    Cardiovascular Institute and Fu Wai Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, 167 BeiLiShi Rd, Beijing 100037, People s Republic of China
    Chest 132:373-9. 2007
    ..To evaluate the clinical features and survival data of patients with idiopathic pulmonary arterial hypertension (PAH) and familial PAH in Chinese patients...
  58. doi Treatment of hepatocellular carcinoma in mice with PE38KDEL type I mutant-loaded poly(lactic-co-glycolic acid) nanoparticles conjugated with humanized SM5-1 F(ab') fragments
    Jie Gao
    International Joint Cancer Institute and Department of Pharmaceutical Science of College of Pharmacy, The Second Military Medical University, Shanghai, People s Republic of China
    Mol Cancer Ther 7:3399-407. 2008
    ..In conclusion, the resultant PE-NP-S possessed increased cancer therapeutic efficacy and had reduced nonspecific toxicity and immunogenicity, suggesting that it is a potential candidate in cancer therapy...
  59. ncbi Effects of continuous high-volume hemofiltration on experimental severe acute pancreatitis in pigs
    Weiqin Li
    Surgical Intensive Care Unit, Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Jiangsu Province, China
    Pancreas 34:112-9. 2007
    ..To compare the effects of different doses of hemofiltration on severe acute pancreatitis (SAP) in pigs...
  60. ncbi Mechanisms of angiotensin II-dependent progression to heart failure
    Mona Nemer
    Research Unit in Cardiac Growth and Differentiation, Institut de recherches cliniques de Montreal IRCM, 110 avenue des Pins Ouest, Montreal, QC H2W 1R7, Canada
    Novartis Found Symp 274:58-68; discussion 68-72, 152-5, 272-6. 2006
    ..The data suggest that targeting Bcl-2 or interfering with mitochondrial dysfunction may offer new therapeutic opportunities for preventing transition from compensated hypertrophy to heart failure...
  61. ncbi Blocking tumor necrosis factor-alpha inhibits folic acid-induced acute renal failure
    Bing Wan
    Joint Immunology Laboratory of Institute of Health Sciences, Chinese Academy of Sciences and Medical College of Shanghai, Jiao Tong University, Shanghai, China
    Exp Mol Pathol 81:211-6. 2006
    ..Furthermore, in vivo administration of anti-TNF-alpha antibody may be proved as an effective approach for acute renal failure prevention and treatment...
  62. ncbi Blockade of LIGHT/HVEM and B7/CD28 signaling facilitates long-term islet graft survival with development of allospecific tolerance
    Kexing Fan
    International Joint Cancer Institute, The Second Military Medical University, Shanghai, PR China
    Transplantation 84:746-54. 2007
    ..The cardiac allografts were significantly prolonged in LIGHT deficient mice. No data are yet available regarding the role of the LIGHT/HVEM pathway in more stringent fully allogeneic models such as skin and islet transplantation models...
  63. ncbi [Liver biopsy in the management of liver dysfunction after allogeneic hematopoietic stem-cell transplantation]
    Huan Chen
    Institute of Hematology, People s Hospital, Peking University, Beijing 100044, China
    Zhonghua Yi Xue Za Zhi 85:3062-6. 2005
    ....
  64. doi Rapid head cooling initiated coincident with cardiopulmonary resuscitation improves success of defibrillation and post-resuscitation myocardial function in a porcine model of prolonged cardiac arrest
    Min Shan Tsai
    J Am Coll Cardiol 51:1988-90. 2008
  65. ncbi Changing patterns of bone and brain metastases in patients with colorectal cancer
    Mark L Sundermeyer
    Department of Medical Oncology, Fox Chase Cancer Center, 333 Cottman Ave, Philadelphia, PA 19111 2497, USA
    Clin Colorectal Cancer 5:108-13. 2005
    ..This study was undertaken to test the hypothesis that expanded treatment options and resultant improved survival for patients with metastatic CRC are associated with an increased incidence of metastases at uncommon sites...
  66. ncbi Effect of cyclophilin A on gene expression in human pancreatic cancer cells
    Min Li
    Molecular Surgeon Research Center, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Surg 190:739-45. 2005
    ..In this study, we further investigated the effect of CypA on gene expression of several key molecules that are involved in pancreatic cancer cell proliferation...