Marianne J van den Heuvel

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. pmc Menstrual cycle hormones induce changes in functional interactions between lymphocytes and decidual vascular endothelial cells
    Marianne J van den Heuvel
    Department of Pediatrics, Child Health Research Institute, 800 Commissioner s Road East, University of Western Ontario, London, Ontario, Canada, N6C 2V5
    J Clin Endocrinol Metab 90:2835-42. 2005
  2. pmc Defibrinated bovine plasma inhibits retroviral transcription by blocking p52 activation of the NFkappaB element in the long terminal repeat
    Marianne J van den Heuvel
    Department of Pediatrics, University of Western Ontario, London, Ontario
    Can J Vet Res 71:119-28. 2007
  3. pmc Purified bovine plasma blocking factor decreases Bovine leukemia virus p24 expression while increasing protein synthesis and transcriptional activity of peripheral blood mononuclear cells in short-term culture
    Marianne J van den Heuvel
    Department of Pathobiology, University of Guelph, Ontario
    Can J Vet Res 69:186-92. 2005
  4. pmc Trafficking of circulating pro-NK cells to the decidualizing uterus: regulatory mechanisms in the mouse and human
    Marianne J van den Heuvel
    Department of Pediatrics, University of Western Ontario, London, Ontario, Canada
    Immunol Invest 34:273-93. 2005
  5. pmc Trafficking of peripheral blood CD56(bright) cells to the decidualizing uterus--new tricks for old dogmas?
    Marianne van den Heuvel
    Department of Pediatrics, University of Western Ontario, Child Health Research Institute, London, Ontario, Canada N6C 2V5
    J Reprod Immunol 67:21-34. 2005
  6. pmc Isolation of a bovine plasma fibronectin-containing complex which inhibits the expression of bovine leukemia virus p24
    Marianne J van den Heuvel
    Department of Pediatrics, University of Western Ontario, Child Health Research Institute, 800 Commissioners Road, London N6C 2V5, Ontario, Canada
    J Virol 79:8164-70. 2005
  7. pmc Periovulatory increases in tissue homing potential of circulating CD56(bright) cells are associated with fertile menstrual cycles
    Marianne J van den Heuvel
    Department of Pediatrics, Child Health Research Institute, 800 Commissioner s Road East, University of Western Ontario, London, Ontario, Canada N6C 2V5
    J Clin Endocrinol Metab 90:3606-13. 2005
  8. ncbi request reprint CD56+ cells are recruited to the uterus in two waves: at ovulation and during the first 2 weeks after missed menses
    Marianne J van den Heuvel
    Department of Pediatrics, Children s Health Research Institute, University of Western Ontario, London, ON, Canada
    Am J Reprod Immunol 59:90-8. 2008
  9. doi request reprint CD56bright cells increase expression of {alpha}4 integrin at ovulation in fertile cycles
    Crystal G Peralta
    Department of Pediatrics, University of Western Ontario, Stratford, ON, Canada N5A 6S6
    J Leukoc Biol 84:1065-74. 2008
  10. doi request reprint Expression of chemokine decoy receptors and their ligands at the porcine maternal-fetal interface
    Jocelyn M Wessels
    Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
    Immunol Cell Biol 89:304-13. 2011

Collaborators

Detail Information

Publications16

  1. pmc Menstrual cycle hormones induce changes in functional interactions between lymphocytes and decidual vascular endothelial cells
    Marianne J van den Heuvel
    Department of Pediatrics, Child Health Research Institute, 800 Commissioner s Road East, University of Western Ontario, London, Ontario, Canada, N6C 2V5
    J Clin Endocrinol Metab 90:2835-42. 2005
    ....
  2. pmc Defibrinated bovine plasma inhibits retroviral transcription by blocking p52 activation of the NFkappaB element in the long terminal repeat
    Marianne J van den Heuvel
    Department of Pediatrics, University of Western Ontario, London, Ontario
    Can J Vet Res 71:119-28. 2007
    ..Thus, we infer that plasma effects are mediated through interference with either p52 translocation to the nucleus or p52 synthesis...
  3. pmc Purified bovine plasma blocking factor decreases Bovine leukemia virus p24 expression while increasing protein synthesis and transcriptional activity of peripheral blood mononuclear cells in short-term culture
    Marianne J van den Heuvel
    Department of Pathobiology, University of Guelph, Ontario
    Can J Vet Res 69:186-92. 2005
    ..Utilizing a human microarray, the RNA messages of 83 genes involved in cell division, cell metabolism, and gene regulation were up-regulated...
  4. pmc Trafficking of circulating pro-NK cells to the decidualizing uterus: regulatory mechanisms in the mouse and human
    Marianne J van den Heuvel
    Department of Pediatrics, University of Western Ontario, London, Ontario, Canada
    Immunol Invest 34:273-93. 2005
    ..Here, we review factors influencing NK cell trafficking to decidualizing murine and human uteri and the differentiation and functions of these cells within the uterus...
  5. pmc Trafficking of peripheral blood CD56(bright) cells to the decidualizing uterus--new tricks for old dogmas?
    Marianne van den Heuvel
    Department of Pediatrics, University of Western Ontario, Child Health Research Institute, London, Ontario, Canada N6C 2V5
    J Reprod Immunol 67:21-34. 2005
    ..Thus, we conclude that the actions of LH, E(2,) and P(4) on NK cells that promote interactions with endothelium and potential uterine homing are indirectly mediated through the responsiveness of other cell types...
  6. pmc Isolation of a bovine plasma fibronectin-containing complex which inhibits the expression of bovine leukemia virus p24
    Marianne J van den Heuvel
    Department of Pediatrics, University of Western Ontario, Child Health Research Institute, 800 Commissioners Road, London N6C 2V5, Ontario, Canada
    J Virol 79:8164-70. 2005
    ..Both the purified protein and the commercially available bovine fibronectin inhibited BLV production in naturally infected peripheral blood mononuclear cells, although the fibronectin was less biologically active...
  7. pmc Periovulatory increases in tissue homing potential of circulating CD56(bright) cells are associated with fertile menstrual cycles
    Marianne J van den Heuvel
    Department of Pediatrics, Child Health Research Institute, 800 Commissioner s Road East, University of Western Ontario, London, Ontario, Canada N6C 2V5
    J Clin Endocrinol Metab 90:3606-13. 2005
    ..These results support the idea that temporal control of NK cell homing to the uterine microenvironment is a prerequisite to pregnancy...
  8. ncbi request reprint CD56+ cells are recruited to the uterus in two waves: at ovulation and during the first 2 weeks after missed menses
    Marianne J van den Heuvel
    Department of Pediatrics, Children s Health Research Institute, University of Western Ontario, London, ON, Canada
    Am J Reprod Immunol 59:90-8. 2008
    ..To support a hypothesis that precursors of uNK cells are recruited from blood, adhesive function of blood CD56+ subsets were assessed during one cycle and during pregnancy...
  9. doi request reprint CD56bright cells increase expression of {alpha}4 integrin at ovulation in fertile cycles
    Crystal G Peralta
    Department of Pediatrics, University of Western Ontario, Stratford, ON, Canada N5A 6S6
    J Leukoc Biol 84:1065-74. 2008
    ....
  10. doi request reprint Expression of chemokine decoy receptors and their ligands at the porcine maternal-fetal interface
    Jocelyn M Wessels
    Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada
    Immunol Cell Biol 89:304-13. 2011
    ..These data indicate that decoy receptors and ligands are expressed at the porcine maternal-fetal interface and dysregulation of decoy receptor (DARC and CCX CKR) transcripts occurs at sites of fetal arrest...
  11. doi request reprint Angiogenic DC-SIGN(+) cells are present at the attachment sites of epitheliochorial placentae
    Nicola F Linton
    Department of Biomedical Sciences, University of Guelph, Guelph, Ontario, Canada
    Immunol Cell Biol 88:63-71. 2010
    ..Thus, gestational features, characteristic of haemochorial placentation, are present in species with distinctly different placentation...
  12. ncbi request reprint Decline in number of elevated blood CD3(+) CD56(+) NKT cells in response to intravenous immunoglobulin treatment correlates with successful pregnancy
    Marianne J van den Heuvel
    Department of Pediatrics, University of Western Ontario, London, ON, Canada
    Am J Reprod Immunol 58:447-59. 2007
    ..In mouse models of pregnant failure, NKT cells appear to be important. However, a mouse model may only be pertinent to a subset of patients, as recurrent pregnancy failure is a heterogenous group...
  13. ncbi request reprint Expression of insulin-like growth factor (IGF) family members in porcine pregnancy
    Germaine Miese-Looy
    Department of Biomedical Sciences, University of Guelph, Ontario, Canada
    J Reprod Dev 58:51-60. 2012
    ..Our results suggest that IGF-I and II and their receptors are differentially expressed at the maternal and fetal components of the attachment site...
  14. pmc Expression of angiogenic basic fibroblast growth factor, platelet derived growth factor, thrombospondin-1 and their receptors at the porcine maternal-fetal interface
    Andrew K Edwards
    Department of Biomedical Science, University of Guelph, Guelph, ON N1G 2W1, Canada
    Reprod Biol Endocrinol 9:5. 2011
    ....
  15. pmc A review of trafficking and activation of uterine natural killer cells
    Marianne J van den Heuvel
    Department of Pediatrics, University of Western Ontario, London, Canada
    Am J Reprod Immunol 54:322-31. 2005
    ..However, functions of uNK cells and regulation of their uterine homing are not fully defined. In mice and women, uNK cells contribute to angiogenesis, a role reviewed here and now addressed in a mammal with an alternative placental type...
  16. pmc NKT cell costimulation: experimental progress and therapeutic promise
    Marianne J van den Heuvel
    Department of Microbiology and Immunology, The University of Western Ontario, London, Ontario, Canada
    Trends Mol Med 17:65-77. 2011
    ..Here, we review recent advances in our understanding of iNKT cell costimulation and discuss potential treatment modalities based on the responsiveness of iNKT cells to disease-tailored glycolipids and select costimulatory ligands...