Glen Van der Kraak
Affiliation: University of Guelph
Van der Kraak G, Matsumoto J, Kim M, Hosmer A. Atrazine and its degradates have little effect on the corticosteroid stress response in the zebrafish. Comp Biochem Physiol C Toxicol Pharmacol. 2015;170:1-7 pubmed publisher
..Overall, these data suggest that atrazine and some of its degradates at the concentrations tested have minimal effects on the cortisol mediated stress response in the zebrafish. ..
Lamb J, Boffetta P, Foster W, Goodman J, Hentz K, Rhomberg L, et al
. Comments on the opinions published by Bergman et al. (2015) on Critical Comments on the WHO-UNEP State of the Science of Endocrine Disrupting Chemicals (Lamb et al., 2014). Regul Toxicol Pharmacol. 2015;73:754-7 pubmed publisher
..emphasizing positive findings over null results); and 3. the lack of a justification for conceptual or practical differences between EDCs and other groups of agents. ..
Castro A, Baptista I, de Moura K, Padilha F, Tonietto J, de Souza A, et al
. Exposure to a Brazilian pulp mill effluent impacts the testis and liver in the zebrafish. Comp Biochem Physiol C Toxicol Pharmacol. 2018;206-207:41-47 pubmed publisher
..Collectively, we provide evidence of short term effects of pulp mill effluent on testicular and hepatic physiology and biochemistry in the zebrafish. ..
Parker W, Pileggi V, Seto P, Chen X, Ogunlaja M, Van Der Kraak G, et al
. Impact of activated sludge configuration and operating conditions on in vitro and in vivo responses and trace organic compound removal. Sci Total Environ. 2014;490:360-9 pubmed publisher
..The results suggest that enhancements to wastewater treatment plants that are associated with improved nitrogen removal can result in enhanced removal of TrOCs and can reduce the harmful effects of the effluents on aquatic biota. ..
Knight O, Van der Kraak G. The role of eicosanoids in 17Î±, 20Î²-dihydroxy-4-pregnen-3-one-induced ovulation and spawning in Danio rerio. Gen Comp Endocrinol. 2015;213:50-8 pubmed publisher
..COX metabolites also appear to be involved in ovulation and spawning but their role remains undefined. ..
Cosme M, Lister A, Van der Kraak G. Inhibition of spawning in zebrafish (Danio rerio): Adverse outcome pathways of quinacrine and ethinylestradiol. Gen Comp Endocrinol. 2015;219:89-101 pubmed publisher
..Histological analysis and gene expression were effective tools in defining the AOPs of QUIN and EE2 while the measurement of reproductive hormones level did not provide much valuable information regarding the toxicant's mode of action. ..