Research Topics
Species | M B UrowitzSummaryAffiliation: University of Toronto Country: Canada Publications
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Publications
Prolonged remission in systemic lupus erythematosusMurray B Urowitz
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University Health Network, Ontario, Canada
J Rheumatol 32:1467-72. 2005..To also determine the frequency of remission utilizing less restrictive definitions, such as allowing shorter period of disease quiescence, persistence of serological activity, or treatment in the absence of clinical disease...
Variability over time and correlates of cholesterol and blood pressure in systemic lupus erythematosus: a longitudinal cohort studyMandana Nikpour
University of Toronto Lupus Clinic and the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, 399 Bathurst Street, Toronto, ON, M5T 2S8, Canada
Arthritis Res Ther 12:R125. 2010..The objective of this study was to describe and quantify variability over time of TC and BP among patients with SLE and to determine their correlates...- Burden of autoantibodies and association with disease activity and damage in systemic lupus erythematosusZ Touma
University of Toronto Lupus Clinic and the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Canada
Clin Exp Rheumatol 28:525-31. 2010..To determine whether immunological burden of autoantibodies as reflected by the number of cumulative antibodies present at inception and after 3 and 5 years is associated with or predicts subsequent disease activity and damage in lupus... - Importance of cumulative exposure to elevated cholesterol and blood pressure in development of atherosclerotic coronary artery disease in systemic lupus erythematosus: a prospective proof-of-concept cohort studyMandana Nikpour
University of Toronto Lupus Clinic and the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, 399 Bathurst Street, Toronto, ON, M5T 2S8, Canada
Arthritis Res Ther 13:R156. 2011.... 
Ability of non-fasting and fasting triglycerides to predict coronary artery disease in lupus patientsZahi Touma
Toronto Western Hospital, Toronto, Canada
Rheumatology (Oxford) 51:528-34. 2012..To test whether non-fasting and fasting triglyceride (TG) levels differ in individual patients and whether TG (non-fasting and fasting) levels predict coronary artery disease (CAD) in lupus patients...- Atherosclerotic vascular events in a single large lupus cohort: prevalence and risk factorsMurray B Urowitz
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, Canada
J Rheumatol 34:70-5. 2007.... - The effect of menopause on disease activity in systemic lupus erythematosusMurray B Urowitz
University of Toronto Lupus Clinic and Toronto Western Hospital, Edith Cavell Wing, 399 Bathurst Street, Toronto, Ontario, M5T 2S8, Canada
J Rheumatol 33:2192-8. 2006..To determine the effect of menopause on disease activity and course of systemic lupus erythematosus (SLE)... - Neurocognitive abnormalities in offspring of mothers with systemic lupus erythematosusM B Urowitz
Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University of Toronto Lupus Clinic, Toronto, Ontario, Canada
Lupus 17:555-60. 2008..The matched analyses of the neuropsychological domains revealed impairment in SLE children compared with matched controls in two of the nine domains: learning and memory and behaviour... - Atherosclerotic vascular events in a multinational inception cohort of systemic lupus erythematosusM B Urowitz
Toronto Western Hospital, Toronto, Ontario, Canada
Arthritis Care Res (Hoboken) 62:881-7. 2010..To describe vascular events during an 8-year followup in a multicenter systemic lupus erythematosus (SLE) inception cohort and their attribution to atherosclerosis... - Contributions of observational cohort studies in systemic lupus erythematosus: the university of toronto lupus clinic experienceMurray B Urowitz
University of Toronto, Toronto, ON, Canada
Rheum Dis Clin North Am 31:211-21, v. 2005..This article uses the University of Toronto Lupus Cohort to illustrate the benefits of observational cohort studies in generating important new knowledge in chronic disease such as systemic lupus erythematosus... - Modification of hypertension and hypercholesterolaemia in patients with systemic lupus erythematosus: a quality improvement studyM B Urowitz
Rheumatology Department, University Health Network, Toronto Western Hospital, Canada
Ann Rheum Dis 65:115-7. 2006..Hypercholesterolaemia and hypertension are risk factors for coronary artery disease in patients with systemic lupus erythematosus (SLE)... - Outcomes in patients with active lupus nephritis requiring immunosuppressives who never received cyclophosphamideMurray B Urowitz
University of Toronto Lupus Clinic, Toronto Western Hospital, Toronto, Ontario, Canada
J Rheumatol 34:1491-6. 2007..To assess outcomes in patients with lupus nephritis treated with immunosuppressives compared to those treated with cyclophosphamide in a cohort study and in a matched cohort study... - Evolution of disease burden over five years in a multicenter inception systemic lupus erythematosus cohortM B Urowitz
Toronto Western Hospital, Toronto, Ontario, Canada
Arthritis Care Res (Hoboken) 64:132-7. 2012..We describe disease activity, damage, and the accrual of key autoantibodies in an inception systemic lupus erythematosus (SLE) cohort... - The SLICC inception cohort for atherosclerosisMurray B Urowitz
University of Toronto Lupus Clinic, Toronto Western Hospital, Room 1E 409, 399 Bathurst Street, Toronto, ON, Canada
Curr Rheumatol Rep 10:281-5. 2008..Additional studies using this cohort are ongoing... - Changing patterns in mortality and disease outcomes for patients with systemic lupus erythematosusMurray B Urowitz
Toronto Western Hospital, Centre for Prognosis Studies in Rheumatic Diseases, Toronto Western Hospital, University Health Network, Toronto, Canada
J Rheumatol 35:2152-8. 2008..We examined changes in mortality and other outcomes over time in a large SLE cohort... - Role of specialty care in the management of patients with systemic lupus erythematosusMurray B Urowitz
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, University Health Network, Toronto Western Hospital, Ontario, Canada
J Rheumatol 29:1207-10. 2002..To determine the role of rheumatologists in the management of systemic lupus erythematosus (SLE)... - Accumulation of coronary artery disease risk factors over three years: data from an international inception cohortM B Urowitz
Centre for Prognosis Studies, Toronto Western Hospital, Toronto, Ontario, Canada
Arthritis Rheum 59:176-80. 2008..To examine the accumulation of risk factors over 3 years in a multicenter, international inception cohort of patients with systemic lupus erythematosus (SLE)... - Hormone replacement therapy in women with systemic lupus erythematosus and risk of cardiovascular diseaseJ Hochman
University of Toronto Lupus Clinic, Toronto Western Hospital, Toronto, Ontario, Canada
Lupus 18:313-7. 2009..0001, HR = 1.11, 95% CI = 1.05, 1.17) and SLEDAI-2K (P = 0.0001, HR = 1.10, 95% CI = 1.05, 1.16) were significantly associated with the risk of CAD. In this small group of patients with SLE, HRT alone did not appear to predispose to CAD... - Clinical manifestations and coronary artery disease risk factors at diagnosis of systemic lupus erythematosus: data from an international inception cohortM B Urowitz
SLICC Registry for Atherosclerosis Coordinating Centre, University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario, Canada
Lupus 16:731-5. 2007..4 months from diagnosis. This cohort will be increased to 1500 patients to be followed yearly for 10 years. This will provide a unique opportunity to evaluate risk factors for accelerated atherosclerosis in SLE... - Outcomes of symptomatic osteonecrosis in 95 patients with systemic lupus erythematosusD D Gladman
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, University Health Network, Toronto Western Hospital, Ontario, Canada
J Rheumatol 28:2226-9. 2001.... - Vitamin D insufficiency in a large female SLE cohortS M A Toloza
University of Toronto Lupus Clinic, Toronto Western Hospital, Toronto, ON, Canada M5T 2S8
Lupus 19:13-9. 2010..In conclusion, sub-optimal vitamin D status is common in women with systemic lupus erythematosus and is related to season, cumulative glucocorticoid dose, and serum creatinine... - Ethnic variation in disease patterns and health outcomes in systemic lupus erythematosusSindhu R Johnson
Division of Rheumatology, Centre for Prognostic Studies in the Rheumatic Diseases, University of Toronto, Toronto, Ontario, Canada
J Rheumatol 33:1990-5. 2006..African-Canadians had a higher prevalence of renal disease and damage. Further investigation into other determinants such as genetic predisposition, treatment, and cultural perceptions is needed... - Variability and correlates of high sensitivity C-reactive protein in systemic lupus erythematosusM Nikpour
University of Toronto Lupus Clinic and the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, Canada
Lupus 18:966-73. 2009..The variability of hsCRP in SLE casts doubt over its usefulness as an independent predictor of CAD risk in this disease and potentially in other chronic inflammatory diseases... - Accurately describing changes in disease activity in Systemic Lupus ErythematosusD D Gladman
The University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, University Health Network, Toronto Western Hospital, Ontario, Canada
J Rheumatol 27:377-9. 2000..To determine whether Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) scores correlate with the clinician's impression of level of disease activity... - Early damage as measured by the SLICC/ACR damage index is a predictor of mortality in systemic lupus erythematosusP Rahman
Centre for Prognosis Studies in the Rheumatic Diseases, The Toronto Western Hospital, University Health Network, Ontario, Canada
Lupus 10:93-6. 2001..013), and a trend toward more cardiovascular disease (P = 0.056), compared to patients who were alive. Early damage as reflected by the initial SLICC/ACR Damage Index is associated with a higher rate of mortality... - Summarizing disease features over time: I. Adjusted mean SLEDAI derivation and application to an index of disease activity in lupusDominique Ibanez
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, 399 Bathurst Street, EC 5 034, Toronto, Ontario, Canada M5T 2S8
J Rheumatol 30:1977-82. 2003..To develop a measurement of lupus disease activity over time... - Association of a gene expression profile from whole blood with disease activity in systemic lupus erythaematosusM Nikpour
University of Toronto Lupus Clinic and Centre for Prognosis Studies in Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, Canada
Ann Rheum Dis 67:1069-75. 2008..To determine whether peripheral blood gene expression of patients with systemic lupus erythaematosus (SLE) correlates with disease activity measured using the SLE Disease Activity Index 2000 (SLEDAI-2K)... - Monoclonal gammopathy in systemic lupus erythematosusY M Ali
Centre for Progrosis Studies, Toronto Hospital Western Division, Toronto, Ontario, Canada
Lupus 16:426-9. 2007..There were no differences in disease manifestations, treatment approaches, or malignancies between SLE patients with and those without monoclonal gammopathy... - The nature and outcome of infection in systemic lupus erythematosusD D Gladman
The University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, University Health Network, Toronto Western Hospital, Ontario, Canada
Lupus 11:234-9. 2002..Until new medications which will control disease activity without predisposing to infection are developed, careful titration of steroids and cytotoxic drugs to control disease activity will remain crucial... - Predictive factors for symptomatic osteonecrosis in patients with systemic lupus erythematosusD D Gladman
Centre for Prognosis Studies in the Rheumatic Diseases, University Health Network, Toronto Western Hospital, Ontario, Canada
J Rheumatol 28:761-5. 2001..CONCLUSION: Glucocorticosteroid therapy, the presence of arthritis, and use of cytotoxic medication are independent risk factors for development of ON in patients with SLE... - SLEDAI-2K 10 days versus SLEDAI-2K 30 days in a longitudinal evaluationZ Touma
Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
Lupus 20:67-70. 2011..SLEDAI-2K 30 days was validated against SLEDAI-2K 10 days in a longitudinal evaluation over 1 year. We recommend the use of SLEDAI-2K 30 days in clinical studies and clinical trials... - SLEDAI-2K Responder Index 50 captures 50% improvement in disease activity over 10 yearsZ Touma
University of Toronto Lupus Clinic, Toronto Western Hospital, Toronto, Ontario, Canada
Lupus 21:1305-11. 2012.... - Osteoporosis in systemic lupus erythematosus: factors associated with referral for bone mineral density studies, prevalence of osteoporosis and factors associated with reduced bone densityC A Pineau
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, University Health Network, Toronto Western Hospital, Toronto, Ontario
Lupus 13:436-41. 2004..Interestingly, disease activity and corticosteroid use were not associated with osteoporosis in this study which may suggest other potential causes such as decreased physical activity associated with damage... - Frequency and determinants of flare and persistently active disease in systemic lupus erythematosusMandana Nikpour
University of Toronto Lupus Clinic and the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, Canada
Arthritis Rheum 61:1152-8. 2009..We sought to elucidate the frequency and determinants of flare and PAD... - Systemic lupus erythematosus disease activity index 2000 responder index-50: a reliable index for measuring improvement in disease activityZahi Touma
Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario, Canada
J Rheumatol 38:868-73. 2011.... - Increased expression of B cell activation factor supports the abnormal expansion of transitional B cells in systemic lupus erythematosusCarolina Landolt-Marticorena
Arthritis Centre of Excellence, Division of Genetics and Development, and the Division of Health Care and Outcomes Research, Toronto Western Hospital Research Institute, University Health Network, Toronto, Ontario, Canada
J Rheumatol 38:642-51. 2011..To examine the relationship between interferon-α (IFN-α) and dysregulation of B cell activation factor (BAFF) and specific B cell phenotypes in systemic lupus erythematosus (SLE)... - Optimal frequency of visits for patients with systemic lupus erythematosus to measure disease activity over timeDominique Ibanez
University of Toronto Lupus Clinic and Centre for Prognosis Studies in the Diseases, University Health Network, Toronto Western Hospital, Toronto, Ontario, Canada
J Rheumatol 38:60-3. 2011..adjusted mean Systemic Lupus Erythematosus Disease Activity Index (SLEDAI; AMS) measures lupus disease activity over time. Our aim was to determine optimal visit frequency for calculating AMS... - Mycophenolate mofetil for induction treatment of lupus nephritis: a systematic review and metaanalysisZahi Touma
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, Canada
J Rheumatol 38:69-78. 2011..to systematically review the efficacy and safety of mycophenolic acid and mycophenolate mofetil (MMF) compared to cyclophosphamide (CYC) for the induction treatment of lupus nephritis (LN)... - The effect of lupus nephritis on pregnancy outcome and fetal and maternal complicationsDafna D Gladman
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Ontario, Canada
J Rheumatol 37:754-8. 2010..To evaluate the effect of lupus nephritis on pregnancy with respect to fetal outcome, maternal complications, and lupus activity... - Clinically active serologically quiescent systemic lupus erythematosusDafna D Gladman
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, 399 Bathurst Street, EC 5-034, Toronto, Ontario, Canada M5T 2S8
J Rheumatol 30:1960-2. 2003..The minority have discordance between clinical and serological status, and are either SACQ or CASQ. Therefore, monitoring both clinical and serological features in patients with SLE is important... - Systemic lupus erythematosus disease activity index 2000Dafna D Gladman
The University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Ontario, Canada
J Rheumatol 29:288-91. 2002..CONCLUSION: SLEDAI-2K, which allows for persistent activity in rash, mucous membranes, alopecia, and proteinuria, is suitable for use in clinical trials and studies of prognosis in SLE... - Lipid profiles in patients with rheumatoid arthritis: mechanisms and the impact of treatmentGeorge Steiner
Department of Medicine, Division of Endocrinology, Toronto General Hospital and University of Toronto, Ontario, Canada
Semin Arthritis Rheum 38:372-81. 2009..To describe the impact of rheumatoid arthritis (RA), and its treatment, on lipoprotein levels with potential implications for atherosclerosis... - Adjusted mean Systemic Lupus Erythematosus Disease Activity Index-2K is a predictor of outcome in SLEDominique Ibanez
Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
J Rheumatol 32:824-7. 2005.... - Myocardial perfusion imaging in assessing risk of coronary events in patients with systemic lupus erythematosusMandana Nikpour
University of Toronto Lupus Clinic and the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, Canada
J Rheumatol 36:288-94. 2009..In this prospective cohort study we investigated whether myocardial perfusion defects in SLE are predictive of CAD events, independently of traditional Framingham risk factors... - Pulmonary hypertension in systemic lupusS R Johnson
University of Toronto Lupus Clinic, Centre for Prognostic Studies in the Rheumatic Diseases, Division of Rheumatology, University of Toronto, Toronto, Canada
Lupus 13:506-9. 2004..Disease activity, organ involvement and anticardiolipin antibodies were not associated with PAH. Further research is needed to identify the mechanism, response to immunosuppression and impact on quality of life in these patients... - KIRs and autoimmune disease: studies in systemic lupus erythematosus and sclerodermaF Pellett
HLA Laboratory, Toronto Western Research Institute, Toronto, Ontario, Canada
Tissue Antigens 69:106-8. 2007..001). This suggests that KIR receptors play a role in susceptibility to both PSS and SLE... - SLEDAI-2K for a 30-day windowZ Touma
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, M5T 2S8, Canada
Lupus 19:49-51. 2010..Thus SLEDAI-2K 30 days is similar to SLEDAI-2K 10 days, both in patients in remission and with a spectrum of disease activity levels. SLEDAI-2K 30 days may now be used to describe disease activity over the previous 30 days... - Relationship between cardiac symptoms, myocardial perfusion defects and coronary angiography findings in systemic lupus erythematosusM Nikpour
University of Toronto Lupus Clinic and the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, Canada
Lupus 20:299-304. 2011..Overall there is poor agreement between the findings of coronary angiography and MPS in SLE, suggesting mechanisms of ischemia other than plaques... - Significance of isolated hematuria and isolated pyuria in systemic lupus erythematosusP Rahman
Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University Health Network, University of Toronto, Ontario, Canada
Lupus 10:418-23. 2001..Thus isolated hematuria and isolated sterile pyuria should be considered manifestations of active SLE... - Accrual of organ damage over time in patients with systemic lupus erythematosusDafna D Gladman
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, 399 Bathurst Street, EC 5-034, Toronto, Ontario, Canada M5T 2S8
J Rheumatol 30:1955-9. 2003..CONCLUSION: While the overall accrual of damage is gradual, the specific systems demonstrate varying patterns of damage accrual... - The effect of pregnancy on lupus nephritisAnu Tandon
Toronto Western Hospital, Toronto, Ontario, Canada
Arthritis Rheum 50:3941-6. 2004..CONCLUSION: During pregnancy in patients with SLE and renal disease, changes in renal disease activity and deterioration in renal function are similar to those which occur in nonpregnant patients with lupus nephritis... - Premature atherosclerosis in systemic lupus erythematosusMandana Nikpour
University of Toronto Lupus Clinic, Toronto Western Hospital, ON M5T 2S8, Canada
Rheum Dis Clin North Am 31:329-54, vii-viii. 2005..The article concludes with a discussion on the important questions that remain to be answered and future directions for research... - Serum albumin as a marker for disease activity in patients with systemic lupus erythematosusJonathan Yip
Division of Health Care and Outcome Research, Toronto Western Research Institute, Toronto, Ontario, Canada
J Rheumatol 37:1667-72. 2010..There is currently no clinical "gold standard" in the assessment of disease activity in SLE... - Single photon emission computed tomography dual isotope myocardial perfusion imaging in women with systemic lupus erythematosus. II. Predictive factors for perfusion abnormalitiesIan N Bruce
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto, Ontario, Canada
J Rheumatol 30:288-91. 2003..Several metabolic and therapy related factors appear to be associated with the process of atherogenesis in SLE. These results suggest that SLE should be considered a predisposing factor for atherosclerosis... - Epidemiology of atherosclerosis in systemic lupus erythematosusMandana Nikpour
University of Toronto Lupus Clinic and the Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Ontario, Canada
Curr Rheumatol Rep 11:248-54. 2009..Elucidation of risk factors and preventive strategies for accelerated atherosclerosis in SLE is the subject of ongoing research... - Fatigue in systemic lupus erythematosus: contributions of disordered sleep, sleepiness, and depressionAndrea Iaboni
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
J Rheumatol 33:2453-7. 2006..Tiredness in SLE that is the result of excessive daytime sleepiness can be distinguished from tiredness of depression. Such distinctions will help identify appropriate treatment for tired patients with SLE... - Risk factors for coronary heart disease in women with systemic lupus erythematosus: the Toronto Risk Factor StudyIan N Bruce
University of Toronto Lupus Clinic, and Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, Canada
Arthritis Rheum 48:3159-67. 2003..These factors are likely to contribute to the loss of protection from CHD that has been observed in SLE... - The impact of the 1997 update of the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus: what has been changed?Marie Feletar
University of Toronto, Toronto Western Hospital, Toronto, Ontario, Canada
Arthritis Rheum 48:2067-9. 2003 - Quality of life over time in patients with systemic lupus erythematosusBindee Kuriya
University of Toronto Lupus Clinic Toronto, Ontario, Canada
Arthritis Rheum 59:181-5. 2008..To determine whether quality of life in patients with systemic lupus erythematosus (SLE) measured by the Short Form 36 (SF-36) changes over time and which patient- and disease-related factors influence such change... - Risk factors for development of coronary artery disease in women with systemic lupus erythematosusRobert J Goldberg
University of Toronto Lupus Clinic, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Division of Rheumatology, University of Toronto, Toronto, Canada
J Rheumatol 36:2454-61. 2009..To ascertain coronary artery disease (CAD) outcomes and predictive factors in a prospective study of patients with systemic lupus erythematosus (SLE) and matched healthy controls... - Systemic Lupus Erythematosus Disease Activity Index 2000 Responder Index-50 enhances the ability of SLE Responder Index to identify responders in clinical trialsZahi Touma
University of Toronto Lupus Clinic, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
J Rheumatol 38:2395-9. 2011..Also, to determine whether the SRI-50 will enhance the ability of SRI in detecting responders... - Is there an advantage over SF-36 with a quality of life measure that is specific to systemic lupus erythematosus?Zahi Touma
Centre for Prognosis Studies in the Rheumatic Diseases, Room 1E 409, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada
J Rheumatol 38:1898-905. 2011.... - Development and initial validation of the systemic lupus erythematosus disease activity index 2000 responder index 50Zahi Touma
Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Room 1E 409, 399 Bathurst Street, Toronto, ON M5T 2S8, Canada
J Rheumatol 38:275-84. 2011..To describe the development and validation of the Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) Responder Index 50 (SRI-50), an index to measure improvement in disease manifestations on followup visits... - Altered expression of TNF-alpha signaling pathway proteins in systemic lupus erythematosusLang jing Zhu
Arthritis Centre of Excellence and Toronto Western Hospital Research Institute, Divisions of Genetics and Development and Population Health, Toronto Western Hospital, Toronto, Ontario, Canada
J Rheumatol 37:1658-66. 2010..To investigate the expression of tumor necrosis factor receptors (TNFR1 and TNFR2) and adapter proteins (TRADD, RIP, and TRAF2) in peripheral blood mononuclear cell (PBMC) subsets from patients with systemic lupus erythematosus (SLE)... - Should all patients with systemic lupus erythematosus receive cardioprotection with statins?Sergio Toloza
Centre for Prognosis Studies in the Rheumatic Diseases at Toronto Western Hospital, in Toronto, ON, Canada
Nat Clin Pract Rheumatol 3:536-7. 2007 - Mortality studies in SLE: how far can we improve survival of patients with SLEMahmoud Abu-Shakra
Autoimmun Rev 3:418-20. 2004 - Systemic lupus international collaborating clinics renal activity/response exercise: comparison of agreement in rating renal responseMichelle Petri
Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
Arthritis Rheum 58:1789-95. 2008..To assess the degree to which physicians agree with each other and with ratings obtained with 3 existing responder indices, in rating the response to treatment of lupus nephritis... - Systemic lupus international collaborating clinics renal activity/response exercise: development of a renal activity score and renal response indexMichelle Petri
Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
Arthritis Rheum 58:1784-8. 2008..To develop a measure of renal activity in systemic lupus erythematosus and use it to develop a renal response index... - Item weightings for the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Disease Damage Index using Rasch analysis do not lead to an important improvementHermine I Brunner
William Rowe Division of Rheumatology, Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
J Rheumatol 30:292-7. 2003.... - The apolipoprotein E2 isoform is associated with accelerated onset of coronary artery disease in systemic lupus erythematosusAntonio Orlacchio
Laboratorio di Neurogenetica, CERC IRCCS Santa Lucia, Rome, Italy and Dipartimento di Neuroscienze, Universita di Roma Tor Vergata, Rome, Italy
Med Sci Monit 14:CR233-237. 2008..It is hypothesized that apolipoprotein E (Apo E), which is involved in cholesterol metabolism, might play a role in this process...