Tracy Tucker

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. pmc Comparison of genome-wide array genomic hybridization platforms for the detection of copy number variants in idiopathic mental retardation
    Tracy Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada
    BMC Med Genomics 4:25. 2011
  2. ncbi Association between benign and malignant peripheral nerve sheath tumors in NF1
    T Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, Canada
    Neurology 65:205-11. 2005
  3. ncbi Increased dental caries in people with neurofibromatosis 1
    T Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, Canada
    Clin Genet 72:524-7. 2007
  4. doi Longitudinal study of neurofibromatosis 1 associated plexiform neurofibromas
    T Tucker
    Department of Medical Genetics, Medical Genetics Research Unit, Children s and Women s Hospital, 4500 Oak Street, Vancouver, BC, Canada
    J Med Genet 46:81-5. 2009
  5. doi Bone health and fracture rate in individuals with neurofibromatosis 1 (NF1)
    T Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada
    J Med Genet 46:259-65. 2009
  6. pmc Massively parallel sequencing: the next big thing in genetic medicine
    Tracy Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Hum Genet 85:142-54. 2009
  7. doi S100B and neurofibromin immunostaining and X-inactivation patterns of laser-microdissected cells indicate a multicellular origin of some NF1-associated neurofibromas
    Tracy Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada
    J Neurosci Res 89:1451-60. 2011
  8. pmc Different patterns of mast cells distinguish diffuse from encapsulated neurofibromas in patients with neurofibromatosis 1
    Tracy Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada
    J Histochem Cytochem 59:584-90. 2011
  9. pmc Single exon-resolution targeted chromosomal microarray analysis of known and candidate intellectual disability genes
    Tracy Tucker
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Eur J Hum Genet 22:792-800. 2014
  10. doi Independent post-zygotic breaks of a dicentric chromosome result in mosaicism for an inverted duplication deletion 9p and terminal deletion 9p
    Kamilla Schlade-Bartusiak
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
    Eur J Med Genet 56:229-35. 2013

Collaborators

Detail Information

Publications13

  1. pmc Comparison of genome-wide array genomic hybridization platforms for the detection of copy number variants in idiopathic mental retardation
    Tracy Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada
    BMC Med Genomics 4:25. 2011
    ..A number of whole genome array genomic hybridization platforms are available, but little is known about their comparative performance in a clinical context...
  2. ncbi Association between benign and malignant peripheral nerve sheath tumors in NF1
    T Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, Canada
    Neurology 65:205-11. 2005
    ..The authors conducted a study to determine whether people with NF1 who have benign neurofibromas of various kinds are at greater risk of developing MPNSTs than patients with NF1 who lack these benign tumors...
  3. ncbi Increased dental caries in people with neurofibromatosis 1
    T Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, Canada
    Clin Genet 72:524-7. 2007
    ..5 +/- 5.8, p = 0.019). Our findings suggest that dental caries occur more frequently than expected among people with NF1 and that individuals with this condition may require a modified dental care program...
  4. doi Longitudinal study of neurofibromatosis 1 associated plexiform neurofibromas
    T Tucker
    Department of Medical Genetics, Medical Genetics Research Unit, Children s and Women s Hospital, 4500 Oak Street, Vancouver, BC, Canada
    J Med Genet 46:81-5. 2009
    ..In order to characterise the growth of plexiform neurofibromas better, we performed serial magnetic resonance imaging (MRI) in NF1 patients with such tumours...
  5. doi Bone health and fracture rate in individuals with neurofibromatosis 1 (NF1)
    T Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada
    J Med Genet 46:259-65. 2009
    ..Patients with neurofibromatosis 1 (NF1) are shorter than expected and often have low bone mineral density (BMD), but the pathogenesis of these bony problems is poorly understood...
  6. pmc Massively parallel sequencing: the next big thing in genetic medicine
    Tracy Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Hum Genet 85:142-54. 2009
    ....
  7. doi S100B and neurofibromin immunostaining and X-inactivation patterns of laser-microdissected cells indicate a multicellular origin of some NF1-associated neurofibromas
    Tracy Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada
    J Neurosci Res 89:1451-60. 2011
    ..Our findings suggest that, although clonal loss of neurofibromin function is probably involved in the development of some NF1-associated neurofibromas, other pathogenic processes also occur...
  8. pmc Different patterns of mast cells distinguish diffuse from encapsulated neurofibromas in patients with neurofibromatosis 1
    Tracy Tucker
    Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada
    J Histochem Cytochem 59:584-90. 2011
    ..The differences in mast cell density and distribution differentiate the two basic types of NF1-associated neurofibromas, suggesting that the pathogenesis of diffuse and encapsulated neurofibromas may be significantly different...
  9. pmc Single exon-resolution targeted chromosomal microarray analysis of known and candidate intellectual disability genes
    Tracy Tucker
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Eur J Hum Genet 22:792-800. 2014
    ....
  10. doi Independent post-zygotic breaks of a dicentric chromosome result in mosaicism for an inverted duplication deletion 9p and terminal deletion 9p
    Kamilla Schlade-Bartusiak
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
    Eur J Med Genet 56:229-35. 2013
    ..Therefore, genotype-phenotype correlations in the inv dup del rearrangements need to take into account the possible presence of other abnormal cell lines during early development...
  11. doi A co-occurrence of osteogenesis imperfecta type VI and cystinosis
    Tracy Tucker
    Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Med Genet A 158:1422-6. 2012
    ..This patient has the concurrent phenotype of two rare recessive diseases, cystinosis and OI type VI. We identified for the first time an in-frame duplication in SERPINF1 that is responsible for the OI type VI phenotype in this patient...
  12. doi Phenotypic heterogeneity in two siblings with 3-methylglutaconic aciduria type I caused by a novel intragenic deletion
    Saadet Mercimek-Mahmutoglu
    Division of Biochemical Diseases, Department of Pediatrics, University of British Columbia, Vancouver, Canada
    Mol Genet Metab 104:410-3. 2011
    ..The diagnosis was confirmed by a demonstration of 3-methylglutaconyl-CoA hydratase enzyme deficiency in the cultured skin fibroblasts and homozygous deletion of exons 1-3 within the AUH gene...
  13. ncbi 60Cobalt vs. linear accelerator in the treatment of locally advanced cervix carcinoma: a comparison of survival and recurrence patterns
    K Holcomb
    Department of Obstetrics and Gynecology, Kings County Hospital and State University of New York-Health Science Center at Brooklyn, USA
    Eur J Gynaecol Oncol 22:16-9. 2001
    ..8%) compared to Group 2 (35.8%, p = .08). CONCLUSIONS: 60Cobalt units and linear accelerators offer comparable rates of overall survival in patients with locally advanced cervix carcinoma...