Dominique Trudel

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. pmc 4FISH-IF, a four-color dual-gene FISH combined with p63 immunofluorescence to evaluate NKX3.1 and MYC status in prostate cancer
    Dominique Trudel
    Department of Laboratory Medicine and Pathology Applied Molecular Oncology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    J Histochem Cytochem 61:500-9. 2013
  2. doi Human epididymis protein 4 (HE4) and ovarian cancer prognosis
    Dominique Trudel
    Laval University Cancer Research Center, Hotel Dieu de Quebec, University Hospital Center CHUQ, 11 Cote du Palais, Quebec, Quebec, Canada
    Gynecol Oncol 127:511-5. 2012
  3. doi Green tea for ovarian cancer prevention and treatment: a systematic review of the in vitro, in vivo and epidemiological studies
    Dominique Trudel
    Laval University Cancer Research Center, Hotel Dieu de Quebec, University Hospital Center CHUQ, 11 Cote du Palais, Quebec, Quebec, Canada
    Gynecol Oncol 126:491-8. 2012
  4. doi Altered DNA methylation landscapes of polycomb-repressed loci are associated with prostate cancer progression and ERG oncogene expression in prostate cancer
    Ken Kron
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Clin Cancer Res 19:3450-61. 2013
  5. doi A two-stage, single-arm, phase II study of EGCG-enriched green tea drink as a maintenance therapy in women with advanced stage ovarian cancer
    Dominique Trudel
    Laval University Cancer Research Center, Hotel Dieu de Quebec, Centre Hospitalier Universitaire CHU de Québec, 11 Cote du Palais, Quebec, Quebec G1R 2J6, Canada Department of Pathology Applied Molecular Oncology, Toronto General Hospital, University Health Network, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada
    Gynecol Oncol 131:357-61. 2013
  6. doi Evaluation and prognostic significance of ACAT1 as a marker of prostate cancer progression
    Punit Saraon
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada
    Prostate 74:372-80. 2014
  7. doi Visual and automated assessment of matrix metalloproteinase-14 tissue expression for the evaluation of ovarian cancer prognosis
    Dominique Trudel
    1 Laval University Cancer Research Center and Research Center of the Centre Hospitalier Universitaire CHU de Qu bec, Qu bec, Canada 2 Department of Pathology Applied Molecular Oncology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    Mod Pathol . 2014
  8. ncbi Prognostic impact of intraductal carcinoma and large cribriform carcinoma architecture after prostatectomy in a contemporary cohort
    Dominique Trudel
    Dept of Pathology and Laboratory Medicine, University Health Network, 200 Elizabeth St, Toronto, ON M5G 2C4, Canada
    Eur J Cancer 50:1610-6. 2014
  9. ncbi Significance of MMP-2 expression in prostate cancer: an immunohistochemical study
    Dominique Trudel
    Departments of Pathology, Laval University, Centre Hospitalier Universitaire de Quebec, L Hôtel Dieu de Québec, Quebec, Canada
    Cancer Res 63:8511-5. 2003
  10. doi Correlation of ERG expression and DNA methylation biomarkers with adverse clinicopathologic features of prostate cancer
    Ken Kron
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Clin Cancer Res 18:2896-904. 2012

Collaborators

Detail Information

Publications13

  1. pmc 4FISH-IF, a four-color dual-gene FISH combined with p63 immunofluorescence to evaluate NKX3.1 and MYC status in prostate cancer
    Dominique Trudel
    Department of Laboratory Medicine and Pathology Applied Molecular Oncology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    J Histochem Cytochem 61:500-9. 2013
    ..Globally, the use of 4FISH-IF decreases analytic time, increases confidence in obtained results, and maintains the tissue morphology of the diagnostic specimen. ..
  2. doi Human epididymis protein 4 (HE4) and ovarian cancer prognosis
    Dominique Trudel
    Laval University Cancer Research Center, Hotel Dieu de Quebec, University Hospital Center CHUQ, 11 Cote du Palais, Quebec, Quebec, Canada
    Gynecol Oncol 127:511-5. 2012
    ..A cohort study was conducted to evaluate whether preoperative plasma HE4 levels could predict the occurrence of death (primary endpoint) and progression (secondary endpoint) in women with ovarian cancer (OC)...
  3. doi Green tea for ovarian cancer prevention and treatment: a systematic review of the in vitro, in vivo and epidemiological studies
    Dominique Trudel
    Laval University Cancer Research Center, Hotel Dieu de Quebec, University Hospital Center CHUQ, 11 Cote du Palais, Quebec, Quebec, Canada
    Gynecol Oncol 126:491-8. 2012
    ..This systematic review was conducted to examine the effects of green tea or green tea components on the prevention and progression of epithelial ovarian cancer...
  4. doi Altered DNA methylation landscapes of polycomb-repressed loci are associated with prostate cancer progression and ERG oncogene expression in prostate cancer
    Ken Kron
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Clin Cancer Res 19:3450-61. 2013
    ....
  5. doi A two-stage, single-arm, phase II study of EGCG-enriched green tea drink as a maintenance therapy in women with advanced stage ovarian cancer
    Dominique Trudel
    Laval University Cancer Research Center, Hotel Dieu de Quebec, Centre Hospitalier Universitaire CHU de Québec, 11 Cote du Palais, Quebec, Quebec G1R 2J6, Canada Department of Pathology Applied Molecular Oncology, Toronto General Hospital, University Health Network, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada
    Gynecol Oncol 131:357-61. 2013
    ..gov, NCT00721890)...
  6. doi Evaluation and prognostic significance of ACAT1 as a marker of prostate cancer progression
    Punit Saraon
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada
    Prostate 74:372-80. 2014
    ..Previously, we identified enzymes of the ketogenic pathway, particularly ACAT1, to be elevated in aggressive prostate cancer...
  7. doi Visual and automated assessment of matrix metalloproteinase-14 tissue expression for the evaluation of ovarian cancer prognosis
    Dominique Trudel
    1 Laval University Cancer Research Center and Research Center of the Centre Hospitalier Universitaire CHU de Qu bec, Qu bec, Canada 2 Department of Pathology Applied Molecular Oncology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    Mod Pathol . 2014
    ..In women with serous carcinoma, high expression of MMP-14 was associated with lower progression.Modern Pathology advance online publication, 7 March 2014; doi:10.1038/modpathol.2014.32...
  8. ncbi Prognostic impact of intraductal carcinoma and large cribriform carcinoma architecture after prostatectomy in a contemporary cohort
    Dominique Trudel
    Dept of Pathology and Laboratory Medicine, University Health Network, 200 Elizabeth St, Toronto, ON M5G 2C4, Canada
    Eur J Cancer 50:1610-6. 2014
    ..The aim of our study was to determine the impact of IDC and LC on biochemical recurrence-free rate (bRFR) in a contemporary prostatectomy cohort...
  9. ncbi Significance of MMP-2 expression in prostate cancer: an immunohistochemical study
    Dominique Trudel
    Departments of Pathology, Laval University, Centre Hospitalier Universitaire de Quebec, L Hôtel Dieu de Québec, Quebec, Canada
    Cancer Res 63:8511-5. 2003
    ..267; P = 0.0012). Increased MMP-2 expression by malignant prostatic epithelia is an independent predictor of decreased prostate cancer disease-free survival...
  10. doi Correlation of ERG expression and DNA methylation biomarkers with adverse clinicopathologic features of prostate cancer
    Ken Kron
    Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada
    Clin Cancer Res 18:2896-904. 2012
    ..The aim of this study was to analyze the relationship between ERG expression, DNA methylation of three biomarkers, and clinicopathologic features of prostate cancer...
  11. pmc Proteomic profiling of androgen-independent prostate cancer cell lines reveals a role for protein S during the development of high grade and castration-resistant prostate cancer
    Punit Saraon
    Samuel Lunenfeld Research Institute, Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada
    J Biol Chem 287:34019-31. 2012
    ..Taken together, these results show that PROS1 is elevated in high grade and castration-resistant prostate cancer and could serve as a potential biomarker of aggressive disease...
  12. doi Randomized clinical trial of vitamin D3 doses on prostatic vitamin D metabolite levels and ki67 labeling in prostate cancer patients
    Dennis Wagner
    Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
    J Clin Endocrinol Metab 98:1498-507. 2013
    ..Vitamin D3 might benefit prostate cancer (PCa) patients because prostate cells can locally synthesize the active hormone calcitriol...
  13. pmc The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis
    Bernard Tetu
    Department of Pathology, Laval University, Quebec, Canada
    Breast Cancer Res 8:R28. 2006
    ..We hypothesized that the individual expression of these three markers or their balance may help to predict breast cancer prognosis...