Catherine H Trepanier

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. pmc Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors via Src kinase
    Catherine Trepanier
    Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 1A8
    Sci Rep 3:926. 2013
  2. ncbi request reprint Neuroinflammation in Alzheimer's disease: are NSAIDs and selective COX-2 inhibitors the next line of therapy?
    Catherine H Trepanier
    Department of Pharmacology, University of Toronto, Toronto, Canada
    J Alzheimers Dis 21:1089-99. 2010
  3. doi request reprint Fyn, a potential target for Alzheimer's disease
    Kai Yang
    Department of Physiology, University of Toronto, Toronto, ON, Canada
    J Alzheimers Dis 27:243-52. 2011
  4. pmc Vasoactive intestinal peptide acts via multiple signal pathways to regulate hippocampal NMDA receptors and synaptic transmission
    Kai Yang
    Department of Physiology, University of Toronto, Toronto, Ontario, Canada
    Hippocampus 19:779-89. 2009
  5. doi request reprint Regulation of NMDA receptors by the tyrosine kinase Fyn
    Catherine H Trepanier
    Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada
    FEBS J 279:12-9. 2012

Collaborators

Detail Information

Publications5

  1. pmc Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors via Src kinase
    Catherine Trepanier
    Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada M5S 1A8
    Sci Rep 3:926. 2013
    ..This represents a potentially novel mechanism to correct the hypoglutamatergic state found in schizophrenia...
  2. ncbi request reprint Neuroinflammation in Alzheimer's disease: are NSAIDs and selective COX-2 inhibitors the next line of therapy?
    Catherine H Trepanier
    Department of Pharmacology, University of Toronto, Toronto, Canada
    J Alzheimers Dis 21:1089-99. 2010
    ..We also review recent anecdotal data with the TNF-α inhibitor, etanercept, and discuss possible explanations for the failure of preclinical data to translate into successful clinical trials...
  3. doi request reprint Fyn, a potential target for Alzheimer's disease
    Kai Yang
    Department of Physiology, University of Toronto, Toronto, ON, Canada
    J Alzheimers Dis 27:243-52. 2011
    ..Novel insights into the role of Fyn in AD may help identify alternative pharmacological approaches for the treatment of AD...
  4. pmc Vasoactive intestinal peptide acts via multiple signal pathways to regulate hippocampal NMDA receptors and synaptic transmission
    Kai Yang
    Department of Physiology, University of Toronto, Toronto, Ontario, Canada
    Hippocampus 19:779-89. 2009
    ..g., 100 nM) was mediated by PAC1-R as well as by Src kinase. Overall, these results show that VIP can regulate NMDA receptors through different receptors and signaling pathways...
  5. doi request reprint Regulation of NMDA receptors by the tyrosine kinase Fyn
    Catherine H Trepanier
    Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada
    FEBS J 279:12-9. 2012
    ..In addition to its effects on NMDA receptor function, Fyn also modifies the threshold for synaptic plasticity at CA1 synapses, an effect that probably contributes to the effects of Fyn on spatial and contextual fear learning...