Research Topics
| Alain TremblaySummaryAffiliation: University of Calgary Country: Canada Publications
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Detail Information
Publications
Use of a drug eluting pleural catheter for pleurodesisAlain Tremblay
Division of Respiratory Medicine, Southern Alberta Cancer Research Institute, Calgary, Alberta, Canada
Exp Lung Res 38:475-82. 2012..Repeated administration of low-dose silver nitrate (SN) has been shown to be effective in creating pleurodesis. This study aimed to determine the effectiveness of a SN-eluting pleural catheter for pleurodesis...
Effect of repeated administration of low-dose silver nitrate for pleurodesis in a rabbit modelAlain Tremblay
Division of Respiratory Medicine and Southern Alberta Cancer Research Institute Division of Pathology and Laboratory Medicine and Institute of Infection, Immunity and Inflammation, University of Calgary, Calgary, Alberta, Canada
Respirology 16:1070-5. 2011..Clinical pleurodesis strategies typically involve single bolus dose administration of drugs. This study was designed to test whether repeated administration of low doses of silver nitrate (SN) could lead to effective pleurodesis...
A randomized controlled trial of standard vs endobronchial ultrasonography-guided transbronchial needle aspiration in patients with suspected sarcoidosisAlain Tremblay
Alain Tremblay, MDUniversity of Calgary, Calgary, AB, Canada
Chest 136:340-6. 2009..The aim of this study was to compare the diagnostic yield of EBUS-guided TBNA to TBNA performed with a standard 19-gauge needle in patients with mediastinal adenopathy and a clinical suspicion of sarcoidosis...
Use of tunnelled catheters for malignant pleural effusions in patients fit for pleurodesisA Tremblay
Division of Respiratory Medicine, Health Sciences Center, Calgary, AB, Canada
Eur Respir J 30:759-62. 2007..Tunnelled pleural catheters are an effective way of controlling malignant pleural effusions when used as first-line treatment in patients who appear to be candidates for pleurodesis procedures...
Endobronchial electrocautery and argon plasma coagulation: a practical approachAlain Tremblay
Division of Respiratory Medicine, University of Calgary, Alberta
Can Respir J 11:305-10. 2004..Advantages of electrocautery, such as low cost, rapid effect, safety and ease of use, are contrasted to other endobronchial therapeutic modalities. Published experience with electrocautery is reviewed...
Single-center experience with 250 tunnelled pleural catheter insertions for malignant pleural effusionAlain Tremblay
Division of Respiratory Medicine, University of Calgary, Health Sciences Center, 3330 Hospital Dr NW, Calgary, AB, T2N 4N1 Canada
Chest 129:362-8. 2006..Malignant pleural effusions (MPEs) are a common cause of dyspnea in patients with advanced cancer. Tunnelled pleural catheters (TPCs) can be used in patients with this condition, but the published experience with them is limited...
Hot biopsy forceps in the diagnosis of endobronchial lesionsA Tremblay
Division of Respiratory Medicine, University of Calgary, Calgary, Canada
Eur Respir J 29:108-11. 2007..Hot biopsy forceps showed a statistically significant reduction in bleeding score, which is unlikely to be of clinical significance...
Wet laboratory versus computer simulation for learning endobronchial ultrasound: a randomized trialDavid Ryan Stather
Department of Medicine, University of Calgary, Alberta, Canada
Can Respir J 19:325-30. 2012..Linear endobronchial ultrasound with transbronchial needle aspiration (EBUS-TBNA) is a revolutionary bronchoscopic procedure that is challenging to learn...
Assessment and learning curve evaluation of endobronchial ultrasound skills following simulation and clinical trainingDavid R Stather
Department of Medicine, University of Calgary, Calgary, Alberta, Canada
Respirology 16:698-704. 2011..This study aims to compare endobronchial ultrasound performance following training with simulation versus conventional training using patients...
Evaluation of clinical endobronchial ultrasound skills following clinical versus simulation trainingDavid R Stather
Department of Medicine, University of Calgary, Calgary, Alberta, Canada
Respirology 17:291-9. 2012..This study aims to compare trainee EBUS-TBNA performance during clinical procedures, following training with a computer EBUS-TBNA simulator versus conventional clinical EBUS-TBNA training...
Validation of an endobronchial ultrasound simulator: differentiating operator skill levelDavid R Stather
Division of Respiratory Medicine, University of Calgary, Calgary, Alta, Canada
Respiration 81:325-32. 2011..Endobronchial ultrasound (EBUS) is a revolutionary diagnostic procedure. There is currently no accepted method of assessing EBUS technical skill or competency...
The impact of tunneled pleural catheters on the quality of life of patients with malignant pleural effusionsNatasha F Sabur
Department of Medicine, University of Calgary, Calgary, Alta, Canada
Respiration 85:36-42. 2013..Tunneled pleural catheters (TPC) are used in the management of malignant pleural effusions (MPE), but the impact of this palliative procedure on patient quality of life (QoL) has not been well described...
Safety of endobronchial ultrasound-guided transbronchial needle aspiration for patients taking clopidogrel: a report of 12 consecutive casesDavid R Stather
Division of Respiratory Medicine, University of Calgary, Calgary, Alta, Canada
Respiration 83:330-4. 2012....
Exercise capacity, lung function, and quality of life after interventional bronchoscopyP Leland Oviatt
Department of Medicine, University of Calgary, Calgary, Alberta, Canada
J Thorac Oncol 6:38-42. 2011..We prospectively assessed the effects of bronchoscopic interventions for the treatment of malignant airway obstruction, with specific attention to exercise capacity and quality of life (QoL)...
Bronchoscopic removal of a large intracavitary pulmonary aspergillomaDavid R Stather
Department of Medicine, University of Calgary, Calgary, AB, Canada
Chest 143:238-41. 2013..To our knowledge, this is the first reported case of bronchoscopic removal of a large cavitary aspergilloma. This important new treatment modality provides a viable alternative therapy for this potentially life-threatening problem...
Cytologic assessment of endobronchial ultrasound-guided transbronchial needle aspirates in sarcoidosisAlex Chee
Division of Respirology, Department of Medicine, Foothills Medical Centre, University of Calgary, Alberta, Canada
J Bronchology Interv Pulmonol 19:24-8. 2012..The purpose of this study was to determine interobserver variability, the relative importance of cytologic preparations, and factors influencing the diagnostic yield of mediastinal lymph node aspirates in suspected sarcoidosis...
Trainee impact on procedural complications: an analysis of 967 consecutive flexible bronchoscopy procedures in an interventional pulmonology practiceDavid R Stather
Division of Respiratory Medicine, Department of Medicine, University of Calgary, Calgary, Alta, Canada
Respiration 85:422-8. 2013..Medical procedural training methods that do not involve practicing on patients warrant further investigation in order to reduce the burden of procedural learning for patients...
Trainee impact on advanced diagnostic bronchoscopy: an analysis of 607 consecutive procedures in an interventional pulmonary practiceDavid Ryan Stather
Division of Respiratory Medicine, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
Respirology 18:179-84. 2013..This study aimed to determine the impact of trainees during advanced diagnostic bronchoscopy on procedure time, sedation use and complications...
Endobronchial ultrasonography: extending the reach of the bronchoscope beyond the airway wallAlain Tremblay
Division of Respiratory Medicine, Department of Medicine, University of Calgary, Calgary, Alta
CMAJ 169:586. 2003
Impact of body mass index on outcomes following critical careAlain Tremblay
Department of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX, USA
Chest 123:1202-7. 2003..To determine the impact of body mass index (BMI) on outcomes in critically ill patients...
[High-frequency endobronchial electrocoagulation]A Tremblay
, , Calgary, AB, Canada
Rev Mal Respir 19:799-803. 2002
An evaluation of procedural training in Canadian respirology fellowship programs: program directors' and fellows' perspectivesD R Stather
University of Calgary, Calgary, Canada
Can Respir J 16:55-9. 2009..In recent years, there has been a rapid growth in diagnostic and therapeutic procedures performed by respirologists...
Endobronchial schwannomaElaine Dumoulin
Department of Medicine, University of Sherbrooke, Sherbrooke, QC, Canada
J Bronchology Interv Pulmonol 19:75-7. 2012..The autofluorescence ratio was <0.5 for 2 of 3 lesions. The optimal follow-up and treatment plan for these lesions remain unknown, especially in asymptomatic patients...
Repair costs for endobronchial ultrasound bronchoscopesChristopher A Hergott
Division of Respirology, Critical Care, and Sleep Medicine, University of Saskatchewan, Saskatoon, Saskatchewan Division of Respiratory Medicine, University of Calgary, Calgary, Alberta, Canada
J Bronchology Interv Pulmonol 17:223-7. 2010..The capital costs associated with implementing EBUS are easily obtained from manufacturers, but the ongoing maintenance and repair costs are unknown...
Role of bronchoscopy in the evaluation of solitary pulmonary nodulesChristopher A Hergott
Division of Respiratory Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
Clin Chest Med 31:49-63, Table of Contents. 2010..Research should focus on combinations of techniques, cost-effectiveness, and incorporation of these tools in diagnostic algorithms for lung nodules/masses...
Pleural controversy: pleurodesis versus indwelling pleural catheters for malignant effusionsPaul MacEachern
Department of Medicine, Division of Respirology, University of Calgary, Southern Alberta Cancer Research Institute, Calgary, Alberta, Canada
Respirology 16:747-54. 2011..Randomized trials directly comparing the two approaches are needed and some are underway. Novel combination approaches utilizing both IPC and pleurodesis agents have the potential to further improve the care of these patients...
Endobronchial Ultrasound Knowledge, Implementation, and Perceived Barriers After Attendance at a Dedicated Hands-on CourseNatasha F Sabur
Division of Respirology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
J Bronchology Interv Pulmonol 18:138-43. 2011..It seems that participation in an EBUS course is useful in helping physicians incorporate EBUS in their practice, but barriers remain, some of which may not be modifiable through such activities...
Endobronchial phototoxicity of WST 09 (Tookad), a new fast-acting photosensitizer for photodynamic therapy: preclinical study in the pigAlain Tremblay
Division of Respiratory Medicine, University of Calgary, Calgary, Alberta, Canada
Photochem Photobiol 78:124-30. 2003..Clinically feasible parameters for drug and light dosimetry were documented. These data will be important in determining safe starting doses for human phase I/II studies...
Bronchial obstruction causing mediastinal shift and hemodynamic compromisePatrik Nechala
Division of Thoracic Surgery, Department of Surgery, University of Calgary, Calgary, Alberta, Canada
Ann Thorac Surg 82:1916. 2006
Simulation in flexible bronchoscopy and endobronchial ultrasound: a reviewDavid Ryan Stather
Department of Medicine, University of Calgary, Calgary, Alberta, Canada Department of Pulmonary and Critical Care, Lahey Clinic, Burlington, MA
J Bronchology Interv Pulmonol 18:247-56. 2011....
Use of tunneled pleural catheters for outpatient treatment of malignant pleural effusionsDavid Ryan Stather
University of Calgary, Calgary, Alberta, Canada
Curr Opin Pulm Med 13:328-33. 2007..Tunneled pleural catheters represent a new safe and effective outpatient treatment option for these patients, with no reported mortality and minimal morbidity...
The use of tunneled pleural catheters in the treatment of pleural effusionsAlex Chee
Division of Respirology, University of Calgary, Canada Southern Alberta Cancer Research Institute, Calgary, Alberta, Canada
Curr Opin Pulm Med 17:237-41. 2011..This article will address the utility of TPCs in malignant pleural effusions, other reported uses, potential complications and catheter maintenance...
Tunnelled pleural catheters in malignant pleural effusionAlain Tremblay
Lancet 370:387; author reply 387. 2007
Real-time electromagnetic navigation bronchoscopy for peripheral lesions: what about the negative predictive value?Alain Tremblay
Chest 131:328-9; author reply 329. 2007
