Affiliation: University of British Columbia
- Conventional MR imagingAnthony Traboulsee
Department of Medicine, Division of Neurology, University of British Columbia, 2211 Wesbrook Mall, Room s199, Vancouver, British Columbia V6T 2B5, Canada
Neuroimaging Clin N Am 18:651-73, x. 2008..Careful communication among clinicians and radiologists will optimize the interpretation of important abnormalities on MR imaging...
- Disability in multiple sclerosis is related to normal appearing brain tissue MTR histogram abnormalitiesA Traboulsee
NMR Research Unit, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK
Mult Scler 9:566-73. 2003..MTR abnormalities in normal appearing brain tissue (NABT) provide quantitative information on the extent of tissue damage undetected by conventional T2-weighted (T2W) magnetic resonance imaging (MRI)...
- MRI: role in optimising treatmentAnthony Traboulsee
Division of Neurology, University of British Columbia, s195 2211 Wesbrook Mall, Vancouver, British Columbia V6T 2B5, Canada
J Neurol 251:v36-v41. 2004..The unique sensitivity of conventional MRI measures for detecting MS pathology has made MRI an attractive tool for optimising treatment in clinical practice for individual patients...
- Neuroimaging in multiple sclerosisAnthony Traboulsee
Division of Neurology, Department of Medicine, The University of British Columbia, S199 2211 Westbrook Mall, Vancouver, British Columbia V6T 2B5, Canada
Neurol Clin 23:131-48, vii. 2005
- Reduction in magnetic resonance imaging T2 burden of disease in patients with relapsing-remitting multiple sclerosis: analysis of 48-week data from the EVIDENCE (EVidence of Interferon Dose-response: European North American Comparative Efficacy) studyA Traboulsee
Division of Neurology, Medicine, University of British Columbia, Vancouver, BC, Canada
BMC Neurol 8:11. 2008....
- MRI relapses have significant pathologic and clinical implications in multiple sclerosisAnthony Traboulsee
Department of Medicine, Division of Neurology, MS MRI Research Group, University of British Columbia, Vancouver, British Columbia, Canada
J Neurol Sci 256:S19-22. 2007..Therefore, new inflammatory activity, as detected by MRI, carries a risk of significant early pathologic damage and delayed yet permanent clinical disability...
- Evaluation of safety monitoring guidelines based on MRI lesion activity in multiple sclerosisC A Riddell
Department of Statistics, University of British Columbia, Vancouver, Canada
Neurology 77:2089-96. 2011....
- Normal-appearing brain tissue MTR histograms in clinically isolated syndromes suggestive of MSA Traboulsee
NMR Research Unit, Institute of Neurology, University College London, United Kingdom
Neurology 59:126-8. 2002..Similar mild NABT abnormality was present with CIS and no further disease activity 14 years later. NABT MTR abnormality in CIS may indicate susceptibility to demyelination but not to disease progression...
- The impact of intensity variations in T1-hypointense lesions on clinical correlations in multiple sclerosisR C Tam
Department of Radiology, University of British Columbia, Vancouver, Canada
Mult Scler 17:949-57. 2011..The degree of hypointensity in black holes is associated with the severity of tissue damage, but the impact on the correlation with disability is unknown...
- Regression of new gadolinium enhancing lesion activity in relapsing-remitting multiple sclerosisYinshan Zhao
Department of Medicine, University of British Columbia, Vancouver, BC, Canada
Neurology 70:1092-7. 2008..Natural regression may confound this strategy. We assessed the degree of regression in monthly new gadolinium activity in relapsing-remitting (RR) placebo patients...
- Does MRI lesion activity regress in secondary progressive multiple sclerosis?Y Zhao
MS MRI Research Group, Department of Medicine, University of British Columbia, Vancouver, Canada
Mult Scler 16:434-42. 2010..The rate of new contrast-enhancing lesions (CELs) on monthly magnetic resonance imaging (MRI) scans has been shown to decrease over a 9-month period in placebo-treated patients with relapsing-remitting (RR) multiple sclerosis (RRMS)...
- The use of MRI as an outcome measure in clinical trialsDavid K B Li
Department of Radiology, University of British Columbia Hospital, Vancouver, Canada
Adv Neurol 98:203-26. 2006....
- Longitudinal changes in myelin water fraction in two MS patients with active diseaseI M Vavasour
Department of Radiology, University of British Columbia, Vancouver, BC, Canada
J Neurol Sci 276:49-53. 2009..This work provides evidence that MWF and WC can monitor demyelination and remyelination in MS...
- Intravenous immunoglobulin in relapsing-remitting multiple sclerosis: a dose-finding trialF Fazekas
Department of Neurology, Medical University of Graz, Auenbruggerplatz 22, A 8036 Graz, Austria
Neurology 71:265-71. 2008..We therefore set out to test two different doses of a new formulation of immunoglobulin termed IGIV-C 10% for suppression of both clinical and MRI disease activity as well as safety...
- Interferons in relapsing remitting multiple sclerosisDon Paty
Lancet 361:1822; author reply 1823-4. 2003
- Longitudinal, regional and deformation-specific corpus callosum shape analysis for multiple sclerosisOmer Ishaq
Medical Image Analysis Lab, School of Computing Science, Simon Fraser University, Burnaby, Canada
Conf Proc IEEE Eng Med Biol Soc 2007:2110-3. 2007..g. by visualizing, say, the 2nd principal mode of shape variation due to bending at the 4th sub-region of the CC) which is useful for developing an intuitive understanding of the effects of MS on the CC shape...