Alan Br Thomson

Summary

Affiliation: University of Alberta
Country: Canada

Publications

  1. ncbi Recommendations for the appropriate use of anti-inflammatory drugs in the era of the coxibs: defining the role of gastroprotective agents
    Richard H Hunt
    Division of Gastroenterology, Department of Medicine, McMaster University Medical Centre, Hamilton, Ontario
    Can J Gastroenterol 16:231-40. 2002
  2. ncbi Mandatory retirement for gastroenterologists: a viewpoint
    Alan B R Thomson
    University of Alberta, Edmonton, Canada
    Can J Gastroenterol 22:125-7. 2008
  3. ncbi Ontogeny, growth and development of the small intestine: Understanding pediatric gastroenterology
    Laurie A Drozdowski
    Division of General Internal Medicine, Department of Medicine, University of Alberta, Alberta, T6G 2B7, Canada
    World J Gastroenterol 16:787-99. 2010
  4. ncbi Gastro-Oesophageal reflux in the elderly: role of drug therapy in management
    A B Thomson
    University of Alberta, Edmonton, Canada
    Drugs Aging 18:409-14. 2001
  5. ncbi Small bowel review: Part II
    A B Thomson
    Cell and Molecular Biology Collaborative Network in Gastrointestinal Physiology, University of Alberta, Edmonton, Alberta T6G 2C2, Canada
    Can J Gastroenterol 15:446-66. 2001
  6. ncbi When acid suppression is not enough: endoscopy and GERD
    Alan B R Thomson
    Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Canada
    Can J Gastroenterol 16:324-6. 2002
  7. ncbi Adaptation following intestinal resection: mechanisms and signals
    A Thiesen
    Nutrition and Metabolism Research Group, Division of Gastroenterology, Department of Medicine, University of Alberta, 519 Newton Research Building, 205 College Plaza, 8215 112 Street, Edmonton, Alta, Canada T6G 2C2
    Best Pract Res Clin Gastroenterol 17:981-95. 2003
  8. ncbi The prevalence of clinically significant endoscopic findings in primary care patients with uninvestigated dyspepsia: the Canadian Adult Dyspepsia Empiric Treatment - Prompt Endoscopy (CADET-PE) study
    A B R Thomson
    University of Alberta, Edmonton, Alberta, Canada
    Aliment Pharmacol Ther 17:1481-91. 2003
  9. ncbi Inhibitory potency of twice-a-day omeprazole on gastric acidity is enhanced by eradication of H. pylori in duodenal ulcer patients
    A B R Thomson
    Nutrition and Metabolism Research Group, University of Alberta, Edmonton, Alberta, Canada
    Dig Dis Sci 48:2045-56. 2003
  10. ncbi Safety of the long-term use of proton pump inhibitors
    Alan Br Thomson
    Division of General Internal Medicine, Faculty of Medicine, University of Alberta, WMC 2F1 08 8440 112 St, Edmonton AB T6G 2B7, Alberta, Canada
    World J Gastroenterol 16:2323-30. 2010

Collaborators

Detail Information

Publications72

  1. ncbi Recommendations for the appropriate use of anti-inflammatory drugs in the era of the coxibs: defining the role of gastroprotective agents
    Richard H Hunt
    Division of Gastroenterology, Department of Medicine, McMaster University Medical Centre, Hamilton, Ontario
    Can J Gastroenterol 16:231-40. 2002
    ..Patients at high risk require a GPA in addition to a coxib...
  2. ncbi Mandatory retirement for gastroenterologists: a viewpoint
    Alan B R Thomson
    University of Alberta, Edmonton, Canada
    Can J Gastroenterol 22:125-7. 2008
  3. ncbi Ontogeny, growth and development of the small intestine: Understanding pediatric gastroenterology
    Laurie A Drozdowski
    Division of General Internal Medicine, Department of Medicine, University of Alberta, Alberta, T6G 2B7, Canada
    World J Gastroenterol 16:787-99. 2010
    ....
  4. ncbi Gastro-Oesophageal reflux in the elderly: role of drug therapy in management
    A B Thomson
    University of Alberta, Edmonton, Canada
    Drugs Aging 18:409-14. 2001
    ....
  5. ncbi Small bowel review: Part II
    A B Thomson
    Cell and Molecular Biology Collaborative Network in Gastrointestinal Physiology, University of Alberta, Edmonton, Alberta T6G 2C2, Canada
    Can J Gastroenterol 15:446-66. 2001
    ..The topics are varied in scope and wherever possible show a logical progression from basic physiology to pathophysiology to clinical disorders and management...
  6. ncbi When acid suppression is not enough: endoscopy and GERD
    Alan B R Thomson
    Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Canada
    Can J Gastroenterol 16:324-6. 2002
  7. ncbi Adaptation following intestinal resection: mechanisms and signals
    A Thiesen
    Nutrition and Metabolism Research Group, Division of Gastroenterology, Department of Medicine, University of Alberta, 519 Newton Research Building, 205 College Plaza, 8215 112 Street, Edmonton, Alta, Canada T6G 2C2
    Best Pract Res Clin Gastroenterol 17:981-95. 2003
    ..An understanding of the mechanisms of, and signals for, intestinal adaptation in the experimental setting forms the basis for the use of management strategies in humans with the short-bowel syndrome...
  8. ncbi The prevalence of clinically significant endoscopic findings in primary care patients with uninvestigated dyspepsia: the Canadian Adult Dyspepsia Empiric Treatment - Prompt Endoscopy (CADET-PE) study
    A B R Thomson
    University of Alberta, Edmonton, Alberta, Canada
    Aliment Pharmacol Ther 17:1481-91. 2003
    ..Uninvestigated dyspepsia is common in family practice. The prevalence of clinically significant upper gastrointestinal findings (CSFs) in adult uninvestigated dyspepsia patients, and their predictability based on history, is unknown...
  9. ncbi Inhibitory potency of twice-a-day omeprazole on gastric acidity is enhanced by eradication of H. pylori in duodenal ulcer patients
    A B R Thomson
    Nutrition and Metabolism Research Group, University of Alberta, Edmonton, Alberta, Canada
    Dig Dis Sci 48:2045-56. 2003
    ..pylori. Thus, in DU the pH-elevating potency of omeprazole taken twice a day is greater in the presence than in the absence of an H. pylori infection...
  10. ncbi Safety of the long-term use of proton pump inhibitors
    Alan Br Thomson
    Division of General Internal Medicine, Faculty of Medicine, University of Alberta, WMC 2F1 08 8440 112 St, Edmonton AB T6G 2B7, Alberta, Canada
    World J Gastroenterol 16:2323-30. 2010
    ..Thus, in summary, the PPIs are a safe class of medications to use long-term in persons in whom there is a clear need for the maintenance of extensive acid inhibition...
  11. ncbi Comparison of the effects of fasting morning, fasting evening and fed bedtime administration of tenatoprazole on intragastric pH in healthy volunteers: a randomized three-way crossover study
    A B R Thomson
    Department of Medicine, Division of Gastroenterology, University of Alberta, Edmonton, Canada
    Aliment Pharmacol Ther 23:1179-87. 2006
    ..The effectiveness of proton pump inhibitors is influenced by meals and administration time...
  12. ncbi Out in left field? A speculative viewpoint on the future
    Alan Thomson
    Department of Medicine, Zeidler Ledcor Centre, Edmonton, Canada
    Can J Gastroenterol 20:697-8. 2006
  13. ncbi The concept of complete remission of gastro-oesophageal reflux disease : comparative efficacy of pantoprazole and esomeprazole using the ReQuest questionnaire
    Alan B R Thomson
    Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Clin Drug Investig 27:663-72. 2007
    ....
  14. ncbi Small intestinal disorders in the elderly
    Alan B R Thomson
    Division of General Internal Medicine, University of Alberta, Edmonton, AB, Canada
    Best Pract Res Clin Gastroenterol 23:861-74. 2009
    ..Pathological alterations which might lead to minor overall intestinal functional variations in the young because of a normal process of adaptation, may lead to much more serious events in the elderly...
  15. ncbi The dyspepsia alphabet: DU, GU, GERD, NERD, NUD/FD and UD
    A B Thomson
    Department of Medicine, University of Alberta, Edmonton, Canada
    Can J Gastroenterol 15:49-55. 2001
    ..This brief overview describes some of the many terms used to describe dyspepsia. Clearly, new treatment algorithms are needed for the care of patients with undiagnosed dyspepsia seen in a primary care setting...
  16. ncbi Are the orally administered proton pump inhibitors equivalent? A comparison of lansoprazole, omeprazole, pantoprazole, and rabeprazole
    A B Thomson
    Division of Gastroenterology, Department of Medicine, University of Alberta, 519 Newton Research Building, Edmonton, AB T6G 2C2, Canada
    Curr Gastroenterol Rep 2:482-93. 2000
    ....
  17. ncbi Small bowel review: Part II
    A B Thomson
    Department of Medicine, University of Alberta, Edmonton
    Can J Gastroenterol 13:37-54. 1999
    ..In preparation for this review, over 500 papers were assessed; some have been selected and reviewed, with a particular focus on presenting clinically useful information for the practising gastroenterologist...
  18. ncbi Small bowel review: Part I
    A B Thomson
    Department of Medicine, University of Alberta, Edmonton
    Can J Gastroenterol 11:515-31. 1997
    ....
  19. ncbi Small bowel review: Part II
    A B Thomson
    Department of Medicine, University of Alberta, Edmonton
    Can J Gastroenterol 11:607-18. 1997
    ....
  20. ncbi Budesonide in the management of patients with Crohn's disease
    A B Thomson
    Division of Gastroenterology, University of Alberta, Edmonton
    Can J Gastroenterol 11:255-60. 1997
    ..Thus, budesonide is the safer, more effective steroid of choice to treat patients with Crohn's disease...
  21. ncbi From bench to bedside and back--report on the European Helicobacter pylori Study Group Xth International Workshop on Gastroduodenal Pathology and Helicobacter pylori
    A B Thomson
    Department of Medicine, University of Alberta, Edmonton
    Can J Gastroenterol 12:437-46. 1998
    ..State-of-the-art reviews and research findings were presented to over 2000 participants. This review focuses on important new developments and serves as a rapid communication of clinically relevant material...
  22. ncbi Small bowel review--Part II
    A B Thomson
    Department of Medicine, University of Alberta, Edmonton
    Can J Gastroenterol 11:159-65. 1997
    ..Part II of this review of the small bowel summarizes the current knowledge about the permeability of the gastrointestinal epithelium, the brush border membrane, motility, carbohydrates, diabetes, ethanol, diet, and diagnostic procedures...
  23. ncbi A suggested approach to patients with dyspepsia
    A B Thomson
    Department of Medicine, University of Alberta, Edmonton
    Can J Gastroenterol 11:135-40. 1997
    ....
  24. ncbi Small bowel review: Part I
    A B Thomson
    Department of Medicine, University of Alberta, Edmonton
    Can J Gastroenterol 12:487-504. 1998
    ..In preparation for this review, over 500 papers were assessed, and some have been selected and reviewed, with a particular focus on presenting clinically useful information for the practising gastroenterologist...
  25. ncbi Influence of food on the bioavailability of an enteric-coated tablet formulation of omeprazole 20 mg under repeated dose conditions
    A B Thomson
    Division of Gastroenterology, University of Alberta, Edmonton
    Can J Gastroenterol 11:663-7. 1997
    ..Thus, under repeated dose conditions, food has no influence on the bioavailability (expressed as AUC) of omeprazole given as the enteric-coated tablet formulation...
  26. ncbi The Second Canadian Gastroesophageal Reflux Disease Consensus: moving forward to new concepts
    A B Thomson
    Department of Medicine, University of Alberta, Edmonton
    Can J Gastroenterol 12:551-6. 1998
    ..e. PKs, H2RAs for 'mild' GERD, versus a PPI for 'severe' disease) is unwarranted...
  27. ncbi Review article: olestra and its gastrointestinal safety
    A B Thomson
    Division of Gastroenterology, University of Alberta, Edmonton, Canada
    Aliment Pharmacol Ther 12:1185-200. 1998
    ....
  28. ncbi Nutrients and intestinal adaptation
    A B Thomson
    Division of Gastroenterology, University of Alberta, Edmonton
    Clin Invest Med 19:331-45. 1996
    ..It may also lead to dietary interventions to prevent unwanted or to enhance desirable intestinal adaptation, thereby preventing disease...
  29. ncbi Small bowel review--Part I
    A B Thomson
    Department of Medicine, University of Alberta, Edmonton
    Can J Gastroenterol 11:49-56. 1997
    ....
  30. ncbi Pharmacokinetics and pharmacodynamics during treatment with the omeprazole 20 mg enteric-coated tablet and 20 mg capsule in asymptomatic duodenal ulcer patients
    A B Thomson
    Division of Gastroenterology, University of Alberta, Edmonton
    Can J Gastroenterol 11:657-60. 1997
    ..5 h longer than to reach the tmax of the capsule. This study indicates that the enteric-coated tablet formulation of omeprazole is biodynamically equivalent to the capsule regarding their effects on intragastric pH during repeated dosing...
  31. ncbi Dexamethasone plus glucagon-like peptide 2 given to lactating rat dams has a late effect on intestinal lipid uptake in the weanling offspring
    Claudiu Iordache
    Nutrition and Metabolism Group, University of Alberta, Edmonton, Alberta, Canada
    JPEN J Parenter Enteral Nutr 28:355-63. 2004
    ..However, the late effects of this treatment on lipid absorption were of concern, and could be potentially deleterious to the nutritional well-being of the animal...
  32. ncbi A combination of dexamethasone and glucagon-like peptide-2 increase intestinal morphology and glucose uptake in suckling rats
    Laurie A Drozdowski
    Nutrition and Metabolism Group, University of Alberta, Edmonton, Alberta, Canada
    J Pediatr Gastroenterol Nutr 42:32-9. 2006
    ..CONCLUSIONS: The combination of these hormones may be useful in stimulating glucose uptake in the developing intestine, and giving DEX to sucklings may enhance glucose uptake in later life...
  33. ncbi Treatment of suckling rats with GLP-2 plus dexamethasone increases the ileal uptake of fatty acids in later life
    Claudiu Iordache
    Nutrition and Metabolism Group, University of Alberta, Edmonton AB T6G 2C8, Canada
    Am J Physiol Gastrointest Liver Physiol 288:G54-9. 2005
    ..It remains to be established what is the nutritional importance of this late effect of prior exposure to Dex or GLP-2 plus Dex on the intestinal uptake of lipids...
  34. ncbi Dietary gangliosides enhance in vitro glucose uptake in weanling rats
    Laurie A Drozdowski
    Nutrition and Metabolism Group, Division of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada
    JPEN J Parenter Enteral Nutr 31:423-9. 2007
    ..2% GANG-enriched diet for 2 weeks alters in vitro intestinal sugar absorption in weanling rats compared with an isocaloric control diet or diet enriched with polyunsaturated long-chain fatty acids...
  35. ncbi Age-associated changes in intestinal fructose uptake are not explained by alterations in the abundance of GLUT5 or GLUT2
    Laurie A Drozdowski
    Nutrition and Metabolism Group, Division of Gastroenterology, Department of Medicine, 5146 Dentistry Pharmacy Building, University of Alberta, Edmonton, AB T6G 2N8, Canada
    J Nutr Biochem 15:630-7. 2004
    ..These results indicate that 1) the effect of age on fructose uptake depends on the method used to express results, and 2) the age-associated changes in uptake are not explained by alterations in GLUT5 and GLUT2...
  36. ncbi Dietary gangliosides enhance in vitro lipid uptake in weanling rats
    Celina J Birecki
    Nutrition and Metabolism Group, Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    J Pediatr Gastroenterol Nutr 42:59-65. 2006
    ..CONCLUSION: We speculate that the enhanced uptake of long-chain fatty acids in weanling rats fed GANG may be caused by a modification in physical properties of the BBM...
  37. ncbi Dexamethasone and GLP-2 given to lactating rat dams influence glucose uptake in suckling and postweanling offspring
    Laurie Drozdowski
    Division of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada
    JPEN J Parenter Enteral Nutr 33:433-9. 2009
    ..The authors hypothesized that GLP-2 and dexamethasone, when administrated to lactating rat dams, enhance sugar uptake in the suckling and postweanling offspring...
  38. ncbi The age-related decline in intestinal lipid uptake is associated with a reduced abundance of fatty acid-binding protein
    Trudy D Woudstra
    Nutrition and Metabolism Group, Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Lipids 39:603-10. 2004
    ..Thus, the decrease with aging in the ileal uptake of some FA when rates were expressed on the basis of mucosal weight was associated with a reduced abundance of I-FABP and ILBP...
  39. ncbi Intestinal sugar transport
    Laurie A Drozdowski
    Division of Gastroenterology, Department of Medicine, University of Alberta, 5150 Dentistry Pharmacy Building, Edmonton, Alberta T6G 2N8, Canada
    World J Gastroenterol 12:1657-70. 2006
    ..This paper reviews the early studies that contributed to the development of a working model of intestinal sugar transport, and details the recent advances made in understanding the process by which sugars are absorbed in the intestine...
  40. ncbi Intestinal mucosal adaptation
    Laurie Drozdowski
    University of Alberta, Edmonton AB, T6G 2N8, Canada
    World J Gastroenterol 12:4614-27. 2006
    ..Identifying factors that may enhance the process of intestinal adaptation is an exciting area of research with important potential clinical applications...
  41. ncbi Maternal dexamethasone and GLP-2 have early effects on intestinal sugar transport in their suckling rat offspring
    Laurie A Drozdowski
    Nutrition and Metabolism Group, Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, AB, Canada T6G2N8
    J Nutr Biochem 20:771-82. 2009
    ..In conclusion, maternal GLP-2 and DEX reduced intestinal sugar uptake in their offspring. This may have nutritional implications for the offspring of mothers treated with GLP-2 or steroids...
  42. ncbi Dexamethasone and GLP-2 administered to rat dams during pregnancy and lactation have late effects on intestinal sugar transport in their postweaning offspring
    Laurie A Drozdowski
    Nutrition and Metabolism Group, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada T6G 2N8
    J Nutr Biochem 19:49-60. 2008
    ..These alterations in uptake may have nutritional implications for the offspring of mothers who may be treated with GLP-2 or glucocorticosteroids...
  43. ncbi An isocaloric PUFA diet enhances lipid uptake and weight gain in aging rats
    Trudy D Woudstra
    Nutrition and Metabolism Group, Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Lipids 39:343-54. 2004
    ..Future studies must determine whether the enhanced lipid uptake and body weight gain observed in older animals fed PUFA have any therapeutic benefit...
  44. ncbi Lack of therapeutic effect of a specially designed yogurt for the eradication of Helicobacter pylori infection
    Chitra N Wendakoon
    Alberta Dairy Association Research Unit, Department of Agricultural, Food and Nutritional Science, Faculty of Agriculture, Forestry and Home Economics, University of Alberta, Edmonton, Alberta, Canada
    Digestion 65:16-20. 2002
    ..pylori in vitro. A clinical trial was conducted to see the efficacy of a specially designed yogurt product containing specific probiotics on the eradication of H. pylori...
  45. ncbi Intracellular lipid binding proteins of the small intestine
    Luis B Agellon
    Canadian Institutes of Health Research Group in Molecular and Cell Biology of Lipids, Department of Biochemistry, University of Alberta, Edmonton, Canada
    Mol Cell Biochem 239:79-82. 2002
    ..In the case of I-FABP, this approach has demonstrated that the complete elimination of this protein in murine intestine does not compromise dietary fat absorption in vivo but is associated with the development of insulin resistance...
  46. ncbi Short-chain fatty acids and total parenteral nutrition affect intestinal gene expression
    Laurie A Drozdowski
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada
    JPEN J Parenter Enteral Nutr 26:145-50. 2002
    ..Accordingly, this study was undertaken to determine the relative role of butyrate in initiating an adaptive response in nonresected rats receiving TPN...
  47. ncbi Small bowel review: Normal physiology, part 1
    Alan B R Thomson
    Nutrition and Metabolism Group, Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Dig Dis Sci 48:1546-64. 2003
  48. ncbi Lipid malabsorption persists after weaning in rats whose dams were given GLP-2 and dexamethasone
    Claudiu Iordache
    Nutrition and Metabolism Group, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Lipids 40:1141-8. 2005
    ..Giving dams GLP-2 or DEX during pregnancy and lactation reduced lipid uptake in the offspring, and this persisted for at least 1 mon. The impact this may have on the nutritional well-being of the animal in later life is unknown...
  49. ncbi Small bowel review: Normal physiology, part 2
    Alan B R Thomson
    Nutrition and Metabolism Group, Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Dig Dis Sci 48:1565-81. 2003
  50. ncbi Acid inhibitory potency of twice a day omeprazole is not affected by eradication of Helicobacter pylori in healthy volunteers
    Alan B R Thomson
    Nutrition and Metabolism Research Group, University of Alberta, Edmonton, AB, Canada
    Helicobacter 8:46-58. 2003
    ..pylori, the acid inhibition with omeprazole was greater in the presence than in the absence of a H. pylori infection. The clinical significance of the small difference is not clear...
  51. ncbi In vitro intestinal glucose uptake is inhibited by galactomannan from Canadian fenugreek seed (Trigonella foenum graecum L) in genetically lean and obese rats
    Anchalee Srichamroen
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5
    Nutr Res 29:49-54. 2009
    ..These results suggest that the galactomannan, because of its viscous property, has the potential to reduce intestinal absorption of low or high concentrations of glucose and hence for the benefit of blood glucose management...
  52. ncbi Necrotizing enterocolitis: a multifactorial disease with no cure
    Kareena L Schnabl
    Alberta Institute for Human Nutrition, 4 10 Ag For Centre, University of Alberta, Edmonton, Alberta T6G 2P5, Canada
    World J Gastroenterol 14:2142-61. 2008
    ....
  53. ncbi 14 day endoscopy study comparing risedronate and alendronate in postmenopausal women stratified by Helicobacter pylori status
    Alan B R Thomson
    University of Alberta, Edmonton, Canada
    J Rheumatol 29:1965-74. 2002
    ..The findings from this 14 day study in healthy volunteers support the hypothesis that bisphosphonates may differ from one another in their potential to produce upper GI mucosal damage...
  54. ncbi Etiology of dyspepsia: implications for empirical therapy
    Richard H Hunt
    Division of Gastroenterology, Department of Medicine, McMaster University, Hamilton, Canada
    Can J Gastroenterol 16:635-41. 2002
    ..Hence, a 'symptom and treat' acid-suppression trial with proton pump inhibitors, and a 'test and treat' strategy for H pylori are two acceptable empirical therapies for patients with univestigated dyspepsia...
  55. ncbi The hepatic retinyl ester hydrolase activity is depressed at the onset of diabetes in BB rats
    Min Chen
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada
    Br J Nutr 89:231-8. 2003
    ..These present results suggest that the depressed hepatic REH activities may contribute to the diabetes-associated metabolic derangement of vitamin A...
  56. ncbi Dietary gangliosides increase the content and molecular percentage of ether phospholipids containing 20:4n-6 and 22:6n-3 in weanling rat intestine
    Eek J Park
    Alberta Institute for Human Nutrition, University of Alberta, Edmonton, Canada T6G 2P5
    J Nutr Biochem 17:337-44. 2006
    ..The present data demonstrate that dietary GG increases the content and composition of EPL containing PUFA in the weanling rat intestine...
  57. ncbi Nutrient absorption and intestinal adaptation with ageing
    Trudy Woudstra
    Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Canada
    Best Pract Res Clin Gastroenterol 16:1-15. 2002
    ..With the continued characterization of the proteins involved in sterol and fatty acid absorption, therapeutic interventions to modify absorption may become available in the future...
  58. ncbi Effect of steroids on intestinal lipid uptake in rats is enhanced by a saturated fatty acid diet. Cell and molecular biology collaborative network in gastrointestinal physiology
    Aducio Thiesen
    Department of Medicine, Division of Gastroenterology, University of Alberta, Edmonton, Canada
    Digestion 68:109-18. 2003
    ....
  59. ncbi Aging and the intestine
    Laurie Drozdowski
    Nutrition and Metabolism Group, University of Alberta, Canada
    World J Gastroenterol 12:7578-84. 2006
    ..The age-associated malabsorption of nutrients that occurs with aging may be one of the several factors which contribute to the malnutrition that occurs with aging...
  60. ncbi Small bowel review: Diseases of the small intestine
    Alan B R Thomson
    Nutrition and Metabolism Group, Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Dig Dis Sci 48:1582-99. 2003
  61. ncbi Protection of intestinal occludin tight junction protein by dietary gangliosides in lipopolysaccharide-induced acute inflammation
    Eek J Park
    Alberta Institute for Human Nutrition, Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada
    J Pediatr Gastroenterol Nutr 50:321-8. 2010
    ....
  62. ncbi Dietary ganglioside decreases cholesterol content, caveolin expression and inflammatory mediators in rat intestinal microdomains
    Eek Joong Park
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5
    Glycobiology 15:935-42. 2005
    ..Dietary gangliosides decrease the cholesterol/ganglioside ratio, caveolin, PAF and DG content in microdomains thus exerting a potential anti-inflammatory effect during gut development...
  63. ncbi Loss of intestinal fatty acid binding protein increases the susceptibility of male mice to high fat diet-induced fatty liver
    Luis B Agellon
    Canadian Institutes of Health Research Molecular and Cell Biology of Lipids Research Group and Department of Biochemistry, University of Alberta, Edmonton, AB, Canada T6G 2S2
    Biochim Biophys Acta 1771:1283-8. 2007
    ..The results obtained demonstrate that loss of I-FABP renders male mice sensitive to high fat diet-induced fatty liver, and this effect is independent of hepatic L-FABP...
  64. ncbi Effect of Helicobacter pylori infection and NSAIDs on the risk of peptic ulcer bleeding
    Varocha Mahachai
    Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
    J Med Assoc Thai 87:S295-9. 2004
    ..The success of eradication should always be confirmed because of the risk of peptic ulcer recurrences and bleeding complication...
  65. ncbi Dietary ganglioside inhibits acute inflammatory signals in intestinal mucosa and blood induced by systemic inflammation of Escherichia coli lipopolysaccharide
    Eek Joong Park
    Nutrition and Metabolism Research Group, Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada
    Shock 28:112-7. 2007
    ....
  66. ncbi Beta-glucan extracts inhibit the in vitro intestinal uptake of long-chain fatty acids and cholesterol and down-regulate genes involved in lipogenesis and lipid transport in rats
    Laurie A Drozdowski
    Nutrition and Metabolism Group, University of Alberta, Edmonton, Alberta, Canada
    J Nutr Biochem 21:695-701. 2010
    ..Dietary fiber reduces the intestinal absorption of nutrients and the blood concentrations of cholesterol and triglycerides...
  67. ncbi Uptake and fate of ganglioside GD3 in human intestinal Caco-2 cells
    Kareena L Schnabl
    Department of Medicine, Division of Gastroenterology, University of Alberta, Edmonton, Alberta T6G 2P5, Canada
    Am J Physiol Gastrointest Liver Physiol 297:G52-9. 2009
    ..This study demonstrates efficient GD3 uptake by enterocytes and suggests that the route of delivery influences ganglioside uptake and fate...
  68. ncbi Beyond the scope of conflict of interest
    Alan B R Thomson
    Can J Gastroenterol 19:75-9. 2005
  69. ncbi Risks and benefits of Helicobacter pylori eradication: current status
    Richard H Hunt
    Department of Medicine, McMaster University, Hamilton, Ontario
    Can J Gastroenterol 16:57-62. 2002
    ..The management guidelines designed specifically in Canada should, therefore, continue to be applied, with H pylori diagnosed and treated in appropriately selected patients...
  70. ncbi Whistler summary: "the slow rate of rapid progress"
    Richard H Hunt
    J Clin Gastroenterol 41:539-45. 2007
  71. ncbi Perhaps the time has come
    Alan B R Thomson
    Can J Gastroenterol 17:613-5. 2003
  72. ncbi Fatty acids in blood and intestine following docosahexaenoic acid supplementation in adults with cystic fibrosis
    Jacqueline A Jumpsen
    Nutrition and Metabolism Research Group, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    J Cyst Fibros 5:77-84. 2006
    ..CONCLUSIONS: The study proves the concept that an increase in tissue DHA levels in CF patients can be achieved by supplementing for six weeks with 70 mg/kg/d DHA...