Affiliation: University of Manitoba
- Toxicokinetics and toxicodynamics of iron poisoningM Tenenbein
Pediatrics, Medicine and Pharmacology, University of Manitoba, Winnipeg, Canada
Toxicol Lett 102:653-6. 1998..Rational treatment of iron poisoning requires a thorough understanding of its toxicokinetics and toxicodynamics...
- Unit-dose packaging of iron supplements and reduction of iron poisoning in young childrenMilton Tenenbein
Department of Pediatrics, University of Manitoba Children s Hospital, Winnipeg
Arch Pediatr Adolesc Med 159:557-60. 2005..Iron poisoning is a major cause of unintentional poisoning death in young children. The US Food and Drug Administration proclaimed a regulation for unit-dose packaging of iron supplements in 1997...
- Hepatotoxicity in acute iron poisoningM Tenenbein
University of Manitoba, Children s Hospital, Winnipeg, Canada
J Toxicol Clin Toxicol 39:721-6. 2001..From the clinical perspective, the relatively high mortality rate of iron poisoning-induced hepatotoxicity requires vigilance for its onset and earlier consideration of liver transplantation...
- The steroid odyssey in croupMilton Tenenbein
Department of Pediatrics, University of Manitoba, Children's Hospital, 840 Sherbrook St, Winnipeg, Manitoba, R3E 1S1, Canada
Pediatrics 116:230-1. 2005
- Do you really need that emergency drug screen?Milton Tenenbein
Children s Hospital, University of Manitoba, Winnipeg, MB, Canada
Clin Toxicol (Phila) 47:286-91. 2009..The purpose of ordering this test is to determine whether the patient's condition is due to a drug. The purpose of this review is to address the question - do you really need that emergency drug screen?..
- Recent advancements in pediatric toxicologyM Tenenbein
Department of Pediatrics, University of Manitoba, Children s Hospital, Winnipeg, Canada
Pediatr Clin North Am 46:1179-88, vii. 1999..The controversy over the type of gastrointestinal decontamination is resolving and recent recommendations are reviewed. Also two new antidotes, fomepizole for toxic alcohols and octreotide for sulfonylureas, are reviewed...
- Acetaminophen: the 150 mg/kg mythMilton Tenenbein
University of Manitoba, Children's Hospital, Winnipeg, Manitoba, Canada
J Toxicol Clin Toxicol 42:145-8. 2004
- Effect of anticholinergic drugs on the efficacy of activated charcoalRobert Green
Department of Emergency Medicine, Internal Medicine, and Pediatrics and Child Health, Faculty of Medicine, University of Manitoba, Children's Hospital, Winnipeg, Manitoba, Canada
J Toxicol Clin Toxicol 42:267-72. 2004..Additional study is required to determine whether in patients with anticholinergic drug overdose, activated charcoal is effective at times beyond the recommendation for overdoses of drugs without this pharmacodynamic effect...
- Oral dexamethasone for the treatment of pain in children with acute pharyngitis: a randomized, double-blind, placebo-controlled trialBlake Bulloch
Department of Pediatrics, Children s Hospital, University of Manitoba, Winnipeg, Canada
Ann Emerg Med 41:601-8. 2003..We compare oral dexamethasone with placebo for the relief of pain in children with acute pharyngitis...
- Acute pancreatitis due to erythromycin overdoseMarshall Stephen Tenenbein
Department of Pediatrics and Child Health, University of Manitoba, Canada
Pediatr Emerg Care 21:675-6. 2005..CONCLUSION: Our case supports transient pancreatitis as a potential consequence of erythromycin overdose...
- Validation of 2 pain scales for use in the pediatric emergency departmentBlake Bulloch
Children s Hospital, Department of Pediatric Emergency Medicine, Winnipeg, Manitoba, Canada
Pediatrics 110:e33. 2002..To determine the construct, content, and convergent validity of 2 self-report pain scales for use in the untrained child in the emergency department (ED)...
- Validation of the Ottawa Knee Rule in children: a multicenter studyBlake Bulloch
Department of Emergency Medicine, Children s Hospital, Winnipeg, Manitoba, Canada
Ann Emerg Med 42:48-55. 2003..The secondary objective was to determine post hoc whether use of the rules would reduce the number of knee radiographs ordered...
- Management of childhood intussusception after reduction by enemaAndrea Wilkie Gilmore
Department of Pediatrics and Child Health, Section of Emergency Medicine, University of Manitoba, Children s Hospital, Winnipeg, Manitoba, Canada R3A 1S1
Am J Emerg Med 29:1136-40. 2011..The objective of the study was to describe the utility of emergency department (ED)/outpatient management after enema reduction for childhood intussusception...
- Constipation: diagnosis and management in the pediatric emergency departmentBlake Bulloch
Department of Pediatrics and Child Health, and the Division of Emergency Medicine, Winnipeg Children's Hospital, Winnipeg, Manitoba, Canada
Pediatr Emerg Care 18:254-8. 2002
- Hepatotoxicity in acute iron poisoningA Robertson
Department of Pediatrics and Pharmacology, University of Manitoba, Children's Hospital, Winnipeg, Canada
Hum Exp Toxicol 24:559-62. 2005..Clinically important hepatotoxicity occurs with values in excess of 1000 microg/dL (182 micromol/L)...
- How long after drug ingestion is activated charcoal still effective?R Green
University of Manitoba, Winnipeg, Canada
J Toxicol Clin Toxicol 39:601-5. 2001..3%, which is similar to previous studies. CONCLUSION: Our data do not support the administration of activated charcoal as a gastrointestinal decontamination strategy beyond 1 hour after drug overdose...
- Interaction between N-acetylcysteine and activated charcoal: implications for the treatment of acetaminophen poisoningP K Tenenbein
Department of Anesthesiology, University of Manitoba, Winnipeg, Canada
Pharmacotherapy 21:1331-6. 2001..001). CONCLUSIONS: The presence of N-acetylcysteine reduces the ability of activated charcoal to adsorb acetaminophen and coingestants. In vivo data will be required to determine the clinical relevance of these interactions...
- Pediatric trauma registries: the foundation of quality careA S Condello
Winnipeg Children's Hospital, University of Manitoba, Winnipeg, Manitoba, Canada
J Pediatr Surg 36:685-9. 2001..Further analysis of data in the registries may clarify these differences and serve as a foundation for hospitals to improve the quality of patient care...
- Effect of whole bowel irrigation on delayed-release acetaminophen and gut transit timeMilton Tenenbein
Ann Emerg Med 44:668-9. 2004
- Whole bowel irrigation and the capsule summaryMilton Tenenbein
Ann Emerg Med 44:666-7; author reply 667; discussion 667-8. 2004
- Iron poisoning in young children: association with the birth of a siblingDavid N Juurlink
Department of Medicine, University of Toronto, Toronto, Ont
CMAJ 168:1539-42. 2003..We explored the association between iron poisoning in young children and the birth of a sibling...
- Multiple doses of activated charcoal: time for reappraisal IIMilton Tenenbein
Ann Emerg Med 42:597-8; author reply 598-9. 2003