Genomes and Genes
Owen J Tamplin
Affiliation: University of Toronto
- Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivativesOwen J Tamplin
Program in Developmental and Stem Cell Biology, Research Institute, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada
BMC Genomics 9:511. 2008..However, the targets of Foxa2 during embryogenesis, and the molecular impact of organizer loss on the gastrula embryo, have not been well defined...
- Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochordOwen J Tamplin
Program in Developmental and Stem Cell Biology, Research Institute, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada
Dev Biol 360:415-25. 2011..The combination of highly specific gene expression profiling and genome-wide ChIP analysis is a powerful means of understanding developmental pathways, even for small cell populations such as the notochord...
- Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanismsYojiro Yamanaka
Program in Developmental and Stem Cell Biology, Hospital for Sick Children Research Institute, Toronto, Ontario M5G 1X8, Canada
Dev Cell 13:884-96. 2007..Therefore, we propose three distinct regions within the mouse notochord, each with unique morphogenetic origins...