Taha Taher

Summary

Affiliation: University of Alberta
Country: Canada

Publications

  1. ncbi request reprint The association among renal insufficiency, pharmacotherapy, and outcomes in 6,427 patients with heart failure and coronary artery disease
    Justin Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada T6G 2R7
    J Am Coll Cardiol 44:1587-92. 2004
  2. doi request reprint Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers are beneficial in normotensive atherosclerotic patients: a collaborative meta-analysis of randomized trials
    Finlay A McAlister
    University of Alberta Hospital, 8440 112 Street, Edmonton, Alberta, Canada
    Eur Heart J 33:505-14. 2012
  3. pmc Risk factors, quality of care and prognosis in South Asian, East Asian and White patients with stroke
    Nadia A Khan
    Department of Medicine, University of British Columbia, 620 B, 1081 Burrard Street, St, Paul s Hospita, Vancouver, BC V6Z 1Y6, Canada
    BMC Neurol 13:74. 2013
  4. doi request reprint The impact of cardiovascular risk-factor profiles on blood pressure control rates in adults from Canada and the United States
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, Alberta, Canada
    Can J Cardiol 29:598-605. 2013
  5. doi request reprint Changes in heart failure outcomes after a province-wide change in health service provision a natural experiment in Alberta, Canada
    Finlay A McAlister
    Divisions of General Internal Medicine, University of Alberta, Edmonton, Alberta, Canada
    Circ Heart Fail 6:76-82. 2013
  6. doi request reprint Renal dysfunction in patients with heart failure with preserved versus reduced ejection fraction: impact of the new Chronic Kidney Disease-Epidemiology Collaboration Group formula
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, AB, Canada
    Circ Heart Fail 5:309-14. 2012
  7. pmc Metformin treatment in diabetes and heart failure: when academic equipoise meets clinical reality
    Dean T Eurich
    School of Public Health, University of Alberta, Edmonton, Alberta, T6G 2G3, Canada
    Trials 10:12. 2009
  8. pmc The SPARK Study: a phase II randomized blinded controlled trial of the effect of furosemide in critically ill patients with early acute kidney injury
    Sean M Bagshaw
    Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 12 Walter C, Mackenzie Centre, 8440 112 Street, Edmonton, Alberta, Canada
    Trials 11:50. 2010
  9. pmc Improving hypertension management through pharmacist prescribing; the rural Alberta clinical trial in optimizing hypertension (Rural RxACTION): trial design and methods
    Theresa L Charrois
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Implement Sci 6:94. 2011
  10. pmc A cluster randomized trial to assess the impact of opinion leader endorsed evidence summaries on improving quality of prescribing for patients with chronic cardiovascular disease: rationale and design [ISRCTN26365328]
    Sumit R Majumdar
    Department of Medicine, University of Alberta, Edmonton AB and the Institute of Health Economics, Edmonton AB, Canada
    BMC Cardiovasc Disord 5:17. 2005

Detail Information

Publications111 found, 100 shown here

  1. ncbi request reprint The association among renal insufficiency, pharmacotherapy, and outcomes in 6,427 patients with heart failure and coronary artery disease
    Justin Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada T6G 2R7
    J Am Coll Cardiol 44:1587-92. 2004
    ..This study was designed to examine the use of cardiovascular medications and outcomes in patients with heart failure (HF) and renal dysfunction...
  2. doi request reprint Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers are beneficial in normotensive atherosclerotic patients: a collaborative meta-analysis of randomized trials
    Finlay A McAlister
    University of Alberta Hospital, 8440 112 Street, Edmonton, Alberta, Canada
    Eur Heart J 33:505-14. 2012
    ..It is unclear whether angiotensin-converting enzyme inhibitors (ACE-I) or angiotensin receptor blockers (ARB) are beneficial in individuals with, or at increased risk for, atherosclerotic vascular disease who are normotensive...
  3. pmc Risk factors, quality of care and prognosis in South Asian, East Asian and White patients with stroke
    Nadia A Khan
    Department of Medicine, University of British Columbia, 620 B, 1081 Burrard Street, St, Paul s Hospita, Vancouver, BC V6Z 1Y6, Canada
    BMC Neurol 13:74. 2013
    ..We compared risk factors, quality of care and risk of death or recurrent stroke in South Asian, East Asian and White patients with acute ischemic and hemorrhagic stroke...
  4. doi request reprint The impact of cardiovascular risk-factor profiles on blood pressure control rates in adults from Canada and the United States
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, Alberta, Canada
    Can J Cardiol 29:598-605. 2013
    ..It is unclear whether blood pressure control varies across the spectrum of atherosclerotic risk...
  5. doi request reprint Changes in heart failure outcomes after a province-wide change in health service provision a natural experiment in Alberta, Canada
    Finlay A McAlister
    Divisions of General Internal Medicine, University of Alberta, Edmonton, Alberta, Canada
    Circ Heart Fail 6:76-82. 2013
    ..The Alberta Cardiac Access (ACA) initiative was implemented in the spring of 2008 to increase access to specialized heart failure (HF) clinics after hospital discharge...
  6. doi request reprint Renal dysfunction in patients with heart failure with preserved versus reduced ejection fraction: impact of the new Chronic Kidney Disease-Epidemiology Collaboration Group formula
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, AB, Canada
    Circ Heart Fail 5:309-14. 2012
    ..The prevalence and prognostic import of renal dysfunction in HF if the CKD-EPI equation is used rather than the MDRD is uncertain...
  7. pmc Metformin treatment in diabetes and heart failure: when academic equipoise meets clinical reality
    Dean T Eurich
    School of Public Health, University of Alberta, Edmonton, Alberta, T6G 2G3, Canada
    Trials 10:12. 2009
    ..Therefore, we attempted to conduct a pilot study to evaluate the feasibility of undertaking a large randomized controlled trial with clinical endpoints...
  8. pmc The SPARK Study: a phase II randomized blinded controlled trial of the effect of furosemide in critically ill patients with early acute kidney injury
    Sean M Bagshaw
    Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, 12 Walter C, Mackenzie Centre, 8440 112 Street, Edmonton, Alberta, Canada
    Trials 11:50. 2010
    ..There remains controversy on whether furosemide can impact clinical outcomes in critically ill patients with AKI; however, a survey of intensivists and nephrologists showed equipoise for high-quality evidence on this important issue...
  9. pmc Improving hypertension management through pharmacist prescribing; the rural Alberta clinical trial in optimizing hypertension (Rural RxACTION): trial design and methods
    Theresa L Charrois
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Implement Sci 6:94. 2011
    ..With Alberta being the first province in Canada to have independent prescribing by pharmacists, it offers a unique opportunity to evaluate outcomes in patients who are prescribed antihypertensive therapy by pharmacists...
  10. pmc A cluster randomized trial to assess the impact of opinion leader endorsed evidence summaries on improving quality of prescribing for patients with chronic cardiovascular disease: rationale and design [ISRCTN26365328]
    Sumit R Majumdar
    Department of Medicine, University of Alberta, Edmonton AB and the Institute of Health Economics, Edmonton AB, Canada
    BMC Cardiovasc Disord 5:17. 2005
    ....
  11. pmc A randomized trial to assess the impact of an antithrombotic decision aid in patients with nonvalvular atrial fibrillation: the DAAFI trial protocol [ISRCTN14429643]
    Finlay A McAlister
    The Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    BMC Cardiovasc Disord 4:5. 2004
    ..This study will evaluate whether an evidence-based patient decision aid for patients with NVAF can improve the appropriateness of antithrombotic therapy use by patients and their family physicians...
  12. ncbi request reprint Multidisciplinary strategies for the management of heart failure patients at high risk for admission: a systematic review of randomized trials
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    J Am Coll Cardiol 44:810-9. 2004
    ..The aim of this study was to determine whether multidisciplinary strategies improve outcomes for heart failure (HF) patients...
  13. pmc The "number needed to treat" turns 20--and continues to be used and misused
    Finlay A McAlister
    Dr McAlister is from The Division of General Internal Medicine, University of Alberta, Edmonton, AB
    CMAJ 179:549-53. 2008
  14. doi request reprint The risk of heart failure in patients with type 2 diabetes treated with oral agent monotherapy
    Finlay A McAlister
    Division of General Internal Medicine, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Eur J Heart Fail 10:703-8. 2008
    ..To determine if the risk of developing heart failure (HF) is associated with the use of sulfonylurea or metformin in patients with diabetes...
  15. ncbi request reprint Systematic review: cardiac resynchronization in patients with symptomatic heart failure
    Finlay A McAlister
    The University of Alberta and Capital Health Evidence based Practice Center, Edmonton, Alberta, Canada
    Ann Intern Med 141:381-90. 2004
    ..Even with optimal pharmacotherapy, symptomatic heart failure is associated with substantial morbidity and mortality...
  16. ncbi request reprint Incidence of and risk factors for pulmonary complications after nonthoracic surgery
    Finlay A McAlister
    Division of General Internal Medicine, Department of Anesthesiology and Critical Care Medicine, University of Alberta, Edmonton, Canada
    Am J Respir Crit Care Med 171:514-7. 2005
    ..7, p < 0.001), and duration of anesthesia (OR 3.3 for operations lasting at least 2.5 hours, p = 0.008). Thus, several perioperative factors predict an increased risk for pulmonary complications after elective nonthoracic surgery...
  17. pmc How evidence-based are the recommendations in evidence-based guidelines?
    Finlay A McAlister
    The Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    PLoS Med 4:e250. 2007
    ..This study was done to evaluate the quality of the evidence (based on consideration of its internal validity, clinical relevance, and applicability) underlying therapy recommendations in evidence-based clinical practice guidelines...
  18. ncbi request reprint Cardiac resynchronization therapy for patients with left ventricular systolic dysfunction: a systematic review
    Finlay A McAlister
    The University of Alberta Evidence based Practice Center, Edmonton, Alberta, Canada
    JAMA 297:2502-14. 2007
    ..Atrial-synchronized biventricular pacemakers (cardiac resynchronization therapy [CRT]) received US Food and Drug Administration (FDA) approval for use in selected patients with LV systolic dysfunction in 2001...
  19. ncbi request reprint Aspirin use and outcomes in a community-based cohort of 7352 patients discharged after first hospitalization for heart failure
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    Circulation 113:2572-8. 2006
    ....
  20. pmc The Canadian Hypertension Education Program--a unique Canadian initiative
    F A McAlister
    Walter Mackenzie Centre, University of Alberta Hospital, 8440 112 Street, Edmonton, Alberta, Canada
    Can J Cardiol 22:559-64. 2006
    ..In the present article, the key features of the Canadian Hypertension Education Program methodology are reviewed, with attention to those factors thought to be critical to the successful translation of recommendations into practice...
  21. pmc The Canadian Hypertension Education Program (CHEP) recommendations: launching a new series
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, Alta
    CMAJ 173:508-9. 2005
  22. pmc Impact of a patient decision aid on care among patients with nonvalvular atrial fibrillation: a cluster randomized trial
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, Alta
    CMAJ 173:496-501. 2005
    ..We tested the short-term (primary outcome) and long-term (secondary outcome) effect of a patient decision aid on the appropriateness of antithrombotic therapy among patients with NVAF...
  23. ncbi request reprint How many patients with heart failure are eligible for cardiac resynchronization? Insights from two prospective cohorts
    Finlay A McAlister
    The Division of General Internal Medicine, 2E3 24 Walter Mackenzie Health Sciences Centre, University of Alberta, 8440 112 Street, Edmonton, Alberta T6G 2R7, Canada
    Eur Heart J 27:323-9. 2006
    ..To determine what proportion of patients with heart failure are eligible for cardiac resynchronization therapy (CRT)...
  24. ncbi request reprint The relation between hyperglycemia and outcomes in 2,471 patients admitted to the hospital with community-acquired pneumonia
    Finlay A McAlister
    2E3 24 WMC, University of Alberta Hospital, 8440 112 Street, Edmonton, Alberta, Canada T6G 2R7
    Diabetes Care 28:810-5. 2005
    ..To examine whether hyperglycemia at the time of presentation was associated with outcomes in patients admitted to non-intensive care settings with community-acquired pneumonia (CAP)...
  25. ncbi request reprint Exploring the treatment-risk paradox in coronary disease
    Finlay A McAlister
    University of Alberta, Edmonton, Alberta, Canada T6G 2R7
    Arch Intern Med 167:1019-25. 2007
    ..The cause of the "treatment-risk paradox" reported for patients with coronary disease is unknown; however, determining the factors that contribute to this paradox is essential to properly design quality improvement interventions...
  26. ncbi request reprint Antihypertensive medication prescribing in 27,822 elderly Canadians with diabetes over the past decade
    Finlay A McAlister
    Department of Medicine, University of Alberta, Edmonton, Alberta T6G 2R7, Canada
    Diabetes Care 29:836-41. 2006
    ..The purpose of this study was to examine whether prescribing practices for elderly individuals with diabetes and hypertension changed over the past decade...
  27. ncbi request reprint Meta-analysis: beta-blocker dose, heart rate reduction, and death in patients with heart failure
    Finlay A McAlister
    University of Alberta Hospital, 2F1 21 Walter Mackenzie Health Sciences Centre, 8440 112 Street, Edmonton, Alberta, Canada
    Ann Intern Med 150:784-94. 2009
    ..Guidelines recommend that patients with heart failure receive beta-blockers in doses used in the trials that have proven their efficacy. Although the adverse effects of beta-blockade are dose-related, it is unclear whether the benefits are...
  28. pmc The Enhancing Secondary Prevention in Coronary Artery Disease trial
    Finlay A McAlister
    Department of Medicine, University of Alberta, the Royal Alexandra Hospital, Edmonton, Alberta
    CMAJ 181:897-904. 2009
    ..We evaluated whether evidence summaries, which were either unsigned or signed by local opinion leaders, improved the quality of secondary prevention care delivered by primary care physicians of patients with coronary artery disease...
  29. pmc Randomised trials of secondary prevention programmes in coronary heart disease: systematic review
    F A McAlister
    Division of General Internal Medicine, University of Alberta Hospital, Edmonton, Alberta, Canada
    BMJ 323:957-62. 2001
    ..To determine whether multidisciplinary disease management programmes for patients with coronary heart disease improve processes of care and reduce morbidity and mortality...
  30. pmc The management of hypertension in Canada: a review of current guidelines, their shortcomings and implications for the future
    F A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, Alta
    CMAJ 164:517-22. 2001
    ..The key points of these guidelines are compared and the shortcomings that may impede their ability to influence practice are discussed. The main implications for future guideline developers are outlined...
  31. ncbi request reprint Commentary: relative treatment effects are consistent across the spectrum of underlying risks...usually
    Finlay A McAlister
    The Division of General Internal Medicine, University of Alberta and the Institute of Health Economics, Edmonton, Alberta, Canada
    Int J Epidemiol 31:76-7. 2002
  32. pmc Changes in the rates of awareness, treatment and control of hypertension in Canada over the past two decades
    Finlay A McAlister
    University of Alberta, Edmonton, Alberta
    CMAJ 183:1007-13. 2011
    ..This study was done to examine the trends in the prevalence of hypertension and in control rates in Canada between 1992 and 2009...
  33. pmc The safety of combining angiotensin-converting-enzyme inhibitors with angiotensin-receptor blockers in elderly patients: a population-based longitudinal analysis
    Finlay A McAlister
    Division of General Internal Medicine and Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alta
    CMAJ 183:655-62. 2011
    ..This study was designed to determine the safety of combination therapy with these two drugs in clinical practice...
  34. pmc When should hypertension be treated? The different perspectives of Canadian family physicians and patients
    F A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton
    CMAJ 163:403-8. 2000
    ....
  35. ncbi request reprint The medical review article revisited: has the science improved?
    F A McAlister
    University of Oxford, United Kingdom
    Ann Intern Med 131:947-51. 1999
    ..The validity of a review depends on its methodologic quality...
  36. ncbi request reprint Accuracy of the preoperative assessment in predicting pulmonary risk after nonthoracic surgery
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    Am J Respir Crit Care Med 167:741-4. 2003
    ..0; p = 0.007). Thus, preoperative factors can identify those patients referred to pulmonologists or internists who are at increased risk for pulmonary complications after nonthoracic surgery...
  37. ncbi request reprint The 2000 Canadian recommendations for the management of hypertension: Part one--therapy
    F A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    Can J Cardiol 17:543-59. 2001
    ..To provide updated, evidence-based recommendations for the therapy of hypertension in adults...
  38. ncbi request reprint Renal insufficiency and heart failure: prognostic and therapeutic implications from a prospective cohort study
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    Circulation 109:1004-9. 2004
    ..The prevalence, prognostic import, and impact of renal insufficiency on the benefits of ACE inhibitors and beta-blockers in community-dwelling patients with heart failure are uncertain...
  39. pmc Treatment of type 2 diabetes and outcomes in patients with heart failure: a nested case-control study from the U.K. General Practice Research Database
    Michael R MacDonald
    Golden Jubilee National Hospital, Glasgow, Scotland
    Diabetes Care 33:1213-8. 2010
    ..We designed this study to determine whether this association reflects a beneficial effect of metformin or a harmful effect of other agents...
  40. pmc The preventing recurrent vascular events and neurological worsening through intensive organized case-management (PREVENTION) trial protocol [clinicaltrials.gov identifier: NCT00931788]
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta Hospital, 8440 112 Street, Edmonton, Canada
    Implement Sci 5:27. 2010
    ..If our intervention improves the provision of secondary prevention therapies in these patients, the clinical (and financial) implications will be enormous...
  41. ncbi request reprint Analysis and reporting of factorial trials: a systematic review
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    JAMA 289:2545-53. 2003
    ....
  42. ncbi request reprint Diabetes and coronary artery bypass surgery: an examination of perioperative glycemic control and outcomes
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta Hospital, Edmonton, Canada
    Diabetes Care 26:1518-24. 2003
    ..To determine the adequacy of perioperative glycemic control in diabetic patients undergoing coronary artery bypass grafting (CABG) and to explore the association between glycemic control and in-hospital morbidity/mortality...
  43. pmc The effect of specialist care within the first year on subsequent outcomes in 24,232 adults with new-onset diabetes mellitus: population-based cohort study
    F A McAlister
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Qual Saf Health Care 16:6-11. 2007
    ..Although specialty care has been shown to improve short-term outcomes in patients hospitalised with acute medical conditions, its effect on patients with chronic conditions treated in the ambulatory care setting is less clear...
  44. ncbi request reprint The 2000 Canadian recommendations for the management of hypertension: part two--diagnosis and assessment of people with high blood pressure
    K B Zarnke
    Department of Medicine, London Health Sciences Centre, University of Western Ontario, 339 Windermere Road, London, Ontario N6A 5A5, Canada
    Can J Cardiol 17:1249-63. 2001
    ..To provide updated, evidence-based recommendations for the diagnosis and assessment of high blood pressure in adults...
  45. pmc Management of hypertension in elderly long-term care residents
    Ross T Tsuyuki
    Department of Medicine, University of Alberta, Alberta, Canada
    Can J Cardiol 24:912-4. 2008
    ..To determine the adequacy of hypertension management in institutionalized elderly patients...
  46. ncbi request reprint The effects of beta-blockers on morbidity and mortality in a population-based cohort of 11,942 elderly patients with heart failure
    Don D Sin
    Department of Pulmonary Medicine DDS, University of Alberta Hospital, Edmonton, Canada
    Am J Med 113:650-6. 2002
    ..However, whether beta-blockers are effective in older patients or those with conditions that would have led to their exclusion from these trials remains unclear...
  47. ncbi request reprint Anemia is common in heart failure and is associated with poor outcomes: insights from a cohort of 12 065 patients with new-onset heart failure
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada
    Circulation 107:223-5. 2003
    ....
  48. ncbi request reprint The 2004 Canadian recommendations for the management of hypertension: Part II--Therapy
    Nadia A Khan
    Division of General Internal Medicine, University of British Columbia, Vancouver, Canada
    Can J Cardiol 20:41-54. 2004
    ..To provide updated, evidence-based recommendations for the management of hypertension in adults...
  49. pmc 2009 Canadian Hypertension Education Program recommendations: the scientific summary--an annual update
    Norman R C Campbell
    Department of Medicine, University of Calgary, Calgary, Canada
    Can J Cardiol 25:271-7. 2009
    ....
  50. pmc Development of a perioperative medicine research agenda: a cross sectional survey
    Nadia A Khan
    Department of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada
    BMC Surg 4:11. 2004
    ..We sought to determine the research priorities for perioperative medicine using a cross sectional survey of Canadian and American general internists...
  51. doi request reprint Cost-effectiveness of a multifaceted intervention to improve quality of osteoporosis care after wrist fracture
    S R Majumdar
    Department of Medicine, University of Alberta, Edmonton, AB, Canada
    Osteoporos Int 22:1799-808. 2011
    ..An economic analysis of the trial now demonstrates that the intervention tested "dominates" usual care: over a lifetime horizon, it reduces fracture, increases quality-adjusted life years, and saves the healthcare system money...
  52. ncbi request reprint Impact of opinion leader-endorsed evidence summaries on the quality of prescribing for patients with cardiovascular disease: a randomized controlled trial
    Sumit R Majumdar
    Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Am Heart J 153:22.e1-8. 2007
    ....
  53. pmc The 2006 Canadian Hypertension Education Program recommendations for the management of hypertension: Part II - Therapy
    N A Khan
    Division of General Internal Medicine, University of British Columbia, Vancouver, BC, Canada
    Can J Cardiol 22:583-93. 2006
    ..To provide updated, evidence-based recommendations for the management of hypertension in adults...
  54. pmc Polytherapy with two or more antihypertensive drugs to lower blood pressure in elderly Ontarians. Room for improvement
    Norman R C Campbell
    Department of Medicine, Libin Cardiovascular Institute, University of Calgary, Calgary, AB, Canada
    Can J Cardiol 23:783-7. 2007
    ..Although guidelines now recommend polytherapy to achieve blood pressure targets, little is know about which antihypertensive drugs are combined in clinical practice...
  55. doi request reprint Effect of beta-blocker use on outcomes after discharge in patients who underwent cardiac surgery
    Anita Y M Chan
    Division of General Internal Medicine, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    J Thorac Cardiovasc Surg 140:182-7, 187.e1. 2010
    ..This study was designed to examine whether discharge use of beta-blockers was associated with outcomes after hospitalization in patients who had undergone nontransplant cardiac surgery...
  56. ncbi request reprint Proportion of patients followed in a specialized heart failure clinic needing an implantable cardioverter defibrillator as determined by applying different trial eligibility criteria
    Mustafa Toma
    Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    Am J Cardiol 97:882-5. 2006
    ..Thus, the development and validation of a risk stratification scheme to identify those patients most likely to benefit from ICDs for primary prophylaxis should be a research priority...
  57. ncbi request reprint Do evidence-based treatments provide incremental benefits to patients with congestive heart failure already receiving angiotensin-converting enzyme inhibitors? A secondary analysis of one-year outcomes from the Assessment of Treatment with Lisinopril and
    Sumit R Majumdar
    Division of General Internal Medicine, Department of Medicine, University of Alberta, 251 Medical Sciences Building, Edmonton, Alberta, Canada T6G 2H7
    Clin Ther 26:694-703. 2004
    ....
  58. ncbi request reprint Improved clinical outcomes associated with metformin in patients with diabetes and heart failure
    Dean T Eurich
    Institute of Health Economics, Edmonton, Alberta, Canada
    Diabetes Care 28:2345-51. 2005
    ..The aim of this study was to evaluate the association between metformin and clinical outcomes in patients with heart failure and type 2 diabetes...
  59. ncbi request reprint New evidence for stroke prevention: scientific review
    Sharon E Straus
    Division of General Internal Medicine, Department of Medicine, University Health Network, Toronto General Hospital, 200 Elizabeth St, ENG 248, Toronto, Ontario, Canada M5G 2C4
    JAMA 288:1388-95. 2002
    ..Stroke is a major cause of morbidity and mortality, and the application of evidence for stroke prevention varies considerably...
  60. pmc Assessment and reporting of perioperative cardiac risk by Canadian general internists: art or science?
    Taha Taher
    Division of General Internal Medicine, University of Alberta, Edmonton, Alberta, Canada
    J Gen Intern Med 17:933-6. 2002
    ..We were interested in evaluating how general internists assess, define, communicate, and attempt to modify perioperative cardiac risk...
  61. ncbi request reprint Resistant hypertension: an overview
    F A McAlister
    Division of General Internal Medicine, University of Alberta Hospital, Edmonton
    Can J Cardiol 12:822-8. 1996
    ..To review the factors contributing to treatment resistance in hypertensive patients and assess the evidence from therapeutic trials in these patients...
  62. ncbi request reprint A systematic review of randomized trials of disease management programs in heart failure
    F A McAlister
    Divisions of General Internal Medicine, University of Alberta Hospital, Edmonton, Canada
    Am J Med 110:378-84. 2001
    ..Data on mortality are inconclusive. Further studies are needed to establish the incremental benefits of the different elements of these programs...
  63. doi request reprint Risk of heart failure in patients with recent-onset type 2 diabetes: population-based cohort study
    Alexander A Leung
    Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Alberta, Canada
    J Card Fail 15:152-7. 2009
    ..Although thiazolidinediones precipitate fluid retention in clinical trials, current guidelines advocate their use for patients with diabetes who are felt to be at low risk for heart failure (HF)...
  64. pmc Impact of specialist follow-up in outpatients with congestive heart failure
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alta
    CMAJ 172:189-94. 2005
    ..Our objective was to determine the impact of physician specialty on outcomes in outpatients with new-onset congestive heart failure...
  65. pmc Evidence of suboptimal management of cardiovascular risk in patients with type 2 diabetes mellitus and symptomatic atherosclerosis
    Lauren C Brown
    Department of Public Health Sciences, University of Alberta, and the Institute of Health Economics, Edmonton
    CMAJ 171:1189-92. 2004
    ..e., coronary artery disease [CAD], cerebrovascular disease [CBVD] or peripheral arterial disease [PAD])...
  66. ncbi request reprint Usefulness of spironolactone in a specialized heart failure clinic
    Wendy Sligl
    Division of General Internal Medicine, Edmonton, Alberta, Canada
    Am J Cardiol 94:443-7. 2004
    ..Thus, although the complication rate was higher, the benefits of spironolactone seen in RALES extended to participants not in a trial who were treated with similar doses and followed closely in a clinic specializing in heart failure...
  67. ncbi request reprint Contemporary management of chronic obstructive pulmonary disease: clinical applications
    S F Paul Man
    Division of Pulmonary Medicine, University of Alberta, Edmonton, Canada
    JAMA 290:2313-6. 2003
    ..Finally, correction of resting arterial hypoxemia with oxygen therapy for more than 15 h/d prolongs survival of COPD patients for those with a resting PaO2 lower than 55 to 60 mm Hg...
  68. doi request reprint Increases in antihypertensive prescriptions and reductions in cardiovascular events in Canada
    Norm R C Campbell
    Department of Medicine, University of Calgary, 3330 Hospital Dr NW, Calgary, Alberta, Canada
    Hypertension 53:128-34. 2009
    ..The Canadian Hypertension Education Program educational model for improving health care could be adopted by other countries with well-developed professional and scientific societies...
  69. ncbi request reprint Aborted myocardial infarction in patients with ST-segment elevation: insights from the Assessment of the Safety and Efficacy of a New Thrombolytic Regimen-3 Trial Electrocardiographic Substudy
    Taha Taher
    University of Alberta, Edmonton, Alberta, Canada
    J Am Coll Cardiol 44:38-43. 2004
    ....
  70. ncbi request reprint Underutilisation of ACE inhibitors in patients with congestive heart failure
    T J Bungard
    Division of Cardiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada
    Drugs 61:2021-33. 2001
    ....
  71. ncbi request reprint Statin use in Type 2 diabetes mellitus is associated with a delay in starting insulin
    A Yee
    Department of General Internal Medicine, University of Alberta, Edmonton, Alberta, Canada
    Diabet Med 21:962-7. 2004
    ..It has been suggested that HMG Co-A reductase inhibitors ('statins') may reduce the risk of developing Type 2 diabetes mellitus. This study was designed to evaluate whether use of statins would also delay progression to insulin therapy...
  72. doi request reprint Heart failure is a risk factor for orthopedic fracture: a population-based analysis of 16,294 patients
    Sean van Diepen
    Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada
    Circulation 118:1946-52. 2008
    ..Heart failure (HF) is associated with factors that may contribute to accelerated bone loss and subsequent fractures. Whether it leads to an increased fracture risk is unknown...
  73. ncbi request reprint New evidence for stroke prevention: clinical applications
    Sharon E Straus
    Division of General Internal Medicine, Department of Medicine, University Health Network, Toronto General Hospital, 200 Elizabeth St, ENG 248, Toronto, Ontario, Canada M5G 2C4
    JAMA 288:1396-8. 2002
    ....
  74. ncbi request reprint Reducing costs and improving hypertension management
    Vida Stankus
    EPICORE Centre, Department of Medicine, University of Alberta, Canada
    Can J Clin Pharmacol 16:e151-5. 2009
    ..To quantify the cost-savings that could be realized by switching patients from two separate agents, ACE inhibitor/ARB and thiazide diuretic, to a fixed dose combination product...
  75. pmc Association between direct measures of body composition and prognostic factors in chronic heart failure
    Antigone Oreopoulos
    School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    Mayo Clin Proc 85:609-17. 2010
    ....
  76. ncbi request reprint Lipid-lowering therapy and outcomes in heart failure
    Joel G Ray
    Department of Medicine, Divisions of General Internal Medicine and Endocrinology and Metabolism, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, Canada
    J Cardiovasc Pharmacol Ther 12:27-35. 2007
    ..More data are needed before statins can be recommended in those with isolated heart failure...
  77. ncbi request reprint Images in cardiovascular medicine. Myocardial infarction as a rare consequence of a snakebite: diagnosis with novel echocardiographic tissue Doppler techniques
    Mohsen Gaballa
    Royal Alexandra Hospital, Edmonton, Alberta, Canada
    Circulation 112:e140-2. 2005
  78. doi request reprint Association between obesity and health-related quality of life in patients with coronary artery disease
    A Oreopoulos
    Department of Clinical Epidemiology, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
    Int J Obes (Lond) 34:1434-41. 2010
    ..Our objective was to determine whether this counterintuitive relationship extends to health-related quality of life (HRQOL) outcomes...
  79. ncbi request reprint Synergy between publication and promotion: comparing adoption of new evidence in Canada and the United States
    Sumit R Majumdar
    Division of Genral Internal Medicine, Department of Medicine, University of Alberta, Edmonton, Canada
    Am J Med 115:467-72. 2003
    ....
  80. doi request reprint Assessing the use of health-related quality of life measures in the routine clinical care of lung-transplant patients
    Maria Jose Santana
    University of Alberta Hospital, Edmonton, Alberta, Canada
    Qual Life Res 19:371-9. 2010
    ..We hypothesized that the inclusion of HRQL in routine clinical care would improve patient-clinician communication, affect clinical management, and improve patients' HRQL...
  81. ncbi request reprint The 2005 Canadian Hypertension Education Program recommendations for the management of hypertension: part II - therapy
    Nadia A Khan
    Division of General Internal Medicine, University of British Columbia, Vancouver, Canada
    Can J Cardiol 21:657-72. 2005
    ..To provide updated, evidence-based recommendations for the management of hypertension in adults...
  82. ncbi request reprint The use of beta-blockers in a tertiary care heart failure clinic: dosing, tolerance, and outcomes
    Puneeta Tandon
    Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    Arch Intern Med 164:769-74. 2004
    ..Little is known about the dosing, tolerability, and impact of beta-blockers in nontrial participants. This study was conducted to evaluate the use and outcomes of beta-blockers in a tertiary care heart failure clinic...
  83. pmc Identification of factors driving differences in cost effectiveness of first-line pharmacological therapy for uncomplicated hypertension
    Scott W Klarenbach
    Department of Medicine, University of Alberta, Edmonton, Alberta
    Can J Cardiol 26:e158-63. 2010
    ..The drivers of these disparities are not clear. Greater understanding is needed for clinicians, researchers and policy makers to determine the most effective and sustainable strategies...
  84. ncbi request reprint Use of angiotensin-converting enzyme inhibitors after coronary artery bypass grafting in patients with diabetes mellitus
    Lana Bistritz
    Division of General Internal Medicine, University of Alberta Hospital, Edmonton, Canada
    Am J Cardiol 92:77-9. 2003
  85. doi request reprint Declining in-hospital mortality and increasing heart failure incidence in elderly patients with first myocardial infarction
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada
    J Am Coll Cardiol 53:13-20. 2009
    ..The purpose of this study was to examine the long-term incidence of heart failure (HF) in elderly patients with myocardial infarction (MI)...
  86. pmc The 2006 Canadian Hypertension Education Program recommendations for the management of hypertension: Part I--Blood pressure measurement, diagnosis and assessment of risk
    B R Hemmelgarn
    Division of Nephrology, University of Calgary, and Foothills Hospital, 1403 29th Street Northwest, Calgary, Alberta, Canada
    Can J Cardiol 22:573-81. 2006
    ..To provide updated, evidence-based recommendations for the diagnosis and assessment of adults with high blood pressure...
  87. doi request reprint Comparison of one-year outcome (death and rehospitalization) in hospitalized heart failure patients with left ventricular ejection fraction >50% versus those with ejection fraction <50%
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Alberta, Edmonton, Canada
    Am J Cardiol 102:79-83. 2008
    ....
  88. doi request reprint The ankle-to-arm blood pressure index predicts risk of cardiac complications after noncardiac surgery
    Bruce W Fisher
    Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    Anesth Analg 107:149-54. 2008
    ..However, the utility of measuring the AAI to predict postoperative cardiac complications in patients undergoing noncardiac surgery is unknown...
  89. ncbi request reprint The 2001 Canadian recommendations for the management of hypertension: Part two--Therapy
    Finlay A McAlister
    University of Alberta Hospital, Edmonton, Canada
    Can J Cardiol 18:625-41. 2002
    ..To provide updated, evidence-based recommendations for the therapy of hypertension in adults...
  90. ncbi request reprint A meta-analysis of the effect of exercise training on left ventricular remodeling in heart failure patients: the benefit depends on the type of training performed
    Mark J Haykowsky
    Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, Alberta, Canada
    J Am Coll Cardiol 49:2329-36. 2007
    ..The aim of this study was to determine the effect of exercise training and type of exercise (aerobic vs. strength vs. combined training) on left ventricular (LV) remodeling in heart failure (HF)...
  91. ncbi request reprint Active-control equivalence trials and antihypertensive agents
    F A McAlister
    Division of General Internal Medicine, University of Alberta, Alberta, Canada
    Am J Med 111:553-8. 2001
    ..The methodological criteria outlined in this article for judging the validity of active-control equivalence trials are not specific to antihypertensive trials and may be applied to trials that test a wide variety of interventions...
  92. pmc Influence of socioeconomic deprivation on the primary care burden and treatment of patients with a diagnosis of heart failure in general practice in Scotland: population based study
    F A McAlister
    Department of Medicine, University of Alberta, Edmonton, AB, Canada T6G 2R7
    BMJ 328:1110. 2004
    ..To examine whether there are socioeconomic gradients in the incidence, prevalence, treatment, and follow up of patients with heart failure in primary care...
  93. doi request reprint Nurse case-manager vs multifaceted intervention to improve quality of osteoporosis care after wrist fracture: randomized controlled pilot study
    S R Majumdar
    Department of Medicine, University of Alberta, 8440 112th Street, Edmonton, Alberta, T6G 2B7, Canada
    Osteoporos Int 22:223-30. 2011
    ....
  94. ncbi request reprint Images in cardiovascular medicine. Sinus of valsalva rupture with dissection into the interventricular septum: diagnosis by echocardiography and magnetic resonance imaging
    Taha Taher
    University of Alberta, Edmonton, Alberta, Canada
    Circulation 111:e101-2. 2005
  95. pmc Cardiovascular outcomes in framingham participants with diabetes: the importance of blood pressure
    Guanmin Chen
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Hypertension 57:891-7. 2011
    ..Although diabetes mellitus is associated with increased risks of death and cardiovascular events in Framingham subjects, much of this excess risk is attributable to coexistent hypertension...
  96. ncbi request reprint The impact of the Canadian Hypertension Education Program on antihypertensive prescribing trends
    Norman R C Campbell
    Department of Medicine, University of Calgary, Calgary, Canada
    Hypertension 47:22-8. 2006
    ....
  97. pmc Re-examining the efficacy of beta-blockers for the treatment of hypertension: a meta-analysis
    Nadia Khan
    Division of General Internal Medicine, University of British Columbia
    CMAJ 174:1737-42. 2006
    ..The primary outcome was a composite of stroke, myocardial infarction and death...
  98. ncbi request reprint Thiazide diuretics for hypertension: prescribing practices and predictors of use in 194,761 elderly patients with hypertension
    Karen Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Am J Geriatr Pharmacother 4:161-7. 2006
    ..Although several small studies have reported underuse of thiazide diuretics for elderly hypertensive patients, those factors which influence initial choice of first-line antihypertensive treatment are unknown...
  99. ncbi request reprint The 2001 Canadian recommendations for the management of hypertension: Part one--Assessment for diagnosis, cardiovascular risk, causes and lifestyle modification
    Kelly B Zarnke
    London Health Sciences Centre, University Hospital Campus, London, Canada
    Can J Cardiol 18:604-24. 2002
    ..To provide updated, evidence-based recommendations for the assessment of the diagnosis, cardiovascular risk, identifiable causes and lifestyle modifications for adults with high blood pressure...
  100. ncbi request reprint The interaction among sex, hemoglobin and outcomes in a specialty heart failure clinic
    Justin A Ezekowitz
    Division of Cardiology, University of Alberta, Edmonton, Alberta T6G 2H7
    Can J Cardiol 21:165-71. 2005
    ..Accordingly, the relationship among sex, anemia and outcomes in CHF was analyzed...
  101. pmc Do beta-blockers have a role in treating hypertension? Yes
    Nadia Khan
    Centre for Health Evaluation and Outcomes Sciences, Division of General Internal Medicine, University of British Columbia, Vancouver
    Can Fam Physician 53:614-21. 2007