Anna Taddio

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. pmc Knowledge translation of the HELPinKIDS clinical practice guideline for managing childhood vaccination pain: usability and knowledge uptake of educational materials directed to new parents
    Anna Taddio
    Clinical Social and Administrative Pharmacy, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario M5S 3M2, Canada
    BMC Pediatr 13:23. 2013
  2. doi request reprint Survey of the prevalence of immunization non-compliance due to needle fears in children and adults
    Anna Taddio
    Clinical, Social and Administrative Pharmacy, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Vaccine 30:4807-12. 2012
  3. doi request reprint Addressing parental concerns about pain during childhood vaccination: is there enough time to include pain management in the ambulatory setting?
    Anna Taddio
    Leslie Dan Faculty of Pharmacy, University of Toronto, Canada
    Clin J Pain 28:238-42. 2012
  4. pmc Ginkgo biloba for the treatment of vitilgo vulgaris: an open label pilot clinical trial
    Orest Szczurko
    Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, 130 Dundas St East, Suite 305, Mississauga, ON L5A 3V8, Canada
    BMC Complement Altern Med 11:21. 2011
  5. doi request reprint Evaluation of the reliability, validity and practicality of 3 measures of acute pain in infants undergoing immunization injections
    Anna Taddio
    Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Vaccine 29:1390-4. 2011
  6. doi request reprint Reliability and validity of observer ratings of pain using the visual analog scale (VAS) in infants undergoing immunization injections
    Anna Taddio
    Leslie Dan Faculty of Pharmacy, University of Toronto, and Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ont, Canada
    Pain 147:141-6. 2009
  7. doi request reprint A randomized controlled trial of analgesia during vaccination in adults
    Anna Taddio
    Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, Canada
    Vaccine 28:5365-9. 2010
  8. doi request reprint Canadian neonatologist practices regarding opioid use in ventilated and spontaneously breathing infants undergoing medical procedures
    Anna Taddio
    Graduate Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Ontario, Canada
    Clin J Pain 26:422-8. 2010
  9. doi request reprint Inadequate pain management during routine childhood immunizations: the nerve of it
    Anna Taddio
    Division of Pharmacy Practice, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Clin Ther 31:S152-67. 2009
  10. doi request reprint Physical interventions and injection techniques for reducing injection pain during routine childhood immunizations: systematic review of randomized controlled trials and quasi-randomized controlled trials
    Anna Taddio
    Division of Pharmacy Practice, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Clin Ther 31:S48-76. 2009

Detail Information

Publications65

  1. pmc Knowledge translation of the HELPinKIDS clinical practice guideline for managing childhood vaccination pain: usability and knowledge uptake of educational materials directed to new parents
    Anna Taddio
    Clinical Social and Administrative Pharmacy, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario M5S 3M2, Canada
    BMC Pediatr 13:23. 2013
    ..The objectives of this study were to evaluate usability and effectiveness in terms of knowledge acquisition from the pamphlet and video in parents of newly born infants...
  2. doi request reprint Survey of the prevalence of immunization non-compliance due to needle fears in children and adults
    Anna Taddio
    Clinical, Social and Administrative Pharmacy, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Vaccine 30:4807-12. 2012
    ....
  3. doi request reprint Addressing parental concerns about pain during childhood vaccination: is there enough time to include pain management in the ambulatory setting?
    Anna Taddio
    Leslie Dan Faculty of Pharmacy, University of Toronto, Canada
    Clin J Pain 28:238-42. 2012
    ....
  4. pmc Ginkgo biloba for the treatment of vitilgo vulgaris: an open label pilot clinical trial
    Orest Szczurko
    Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, 130 Dundas St East, Suite 305, Mississauga, ON L5A 3V8, Canada
    BMC Complement Altern Med 11:21. 2011
    ..Vitiligo is a common hypopigmentation disorder with significant psychological impact if occurring before adulthood. A pilot clinical trial to determine the feasibility of an RCT was conducted and is reported here...
  5. doi request reprint Evaluation of the reliability, validity and practicality of 3 measures of acute pain in infants undergoing immunization injections
    Anna Taddio
    Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Vaccine 29:1390-4. 2011
    ..The majority of raters (4 out of 5) preferred the MBPS. Together, these results provide preliminary support for the MBPS as the primary outcome of pain during vaccine injections in infants...
  6. doi request reprint Reliability and validity of observer ratings of pain using the visual analog scale (VAS) in infants undergoing immunization injections
    Anna Taddio
    Leslie Dan Faculty of Pharmacy, University of Toronto, and Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ont, Canada
    Pain 147:141-6. 2009
    ..However, different conclusions may be reached about the effectiveness of analgesic interventions depending on the rater. Sources of variability include use of multiple raters, rater focus (procedure vs. child) and experience level...
  7. doi request reprint A randomized controlled trial of analgesia during vaccination in adults
    Anna Taddio
    Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario, Canada
    Vaccine 28:5365-9. 2010
    ..This information can be incorporated in immunization programs...
  8. doi request reprint Canadian neonatologist practices regarding opioid use in ventilated and spontaneously breathing infants undergoing medical procedures
    Anna Taddio
    Graduate Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Ontario, Canada
    Clin J Pain 26:422-8. 2010
    ..Opioids are indicated for the management of procedural pain in neonates. There are limited data describing factors influencing patterns of use...
  9. doi request reprint Inadequate pain management during routine childhood immunizations: the nerve of it
    Anna Taddio
    Division of Pharmacy Practice, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Clin Ther 31:S152-67. 2009
    ..Immunization is regarded as one of the most significant medical achievements of all time. Recently, increasing attention has been paid to the pain resulting from routine childhood immunizations...
  10. doi request reprint Physical interventions and injection techniques for reducing injection pain during routine childhood immunizations: systematic review of randomized controlled trials and quasi-randomized controlled trials
    Anna Taddio
    Division of Pharmacy Practice, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Clin Ther 31:S48-76. 2009
    ..Their effectiveness, however, has not previously been studied using a systematic approach...
  11. pmc Effectiveness of sucrose analgesia in newborns undergoing painful medical procedures
    Anna Taddio
    Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    CMAJ 179:37-43. 2008
    ..Our objectives were to evaluate the effectiveness and safety of sucrose in newborns undergoing various medical procedures within 2 days of birth...
  12. doi request reprint Reduced infant response to a routine care procedure after sucrose analgesia
    Anna Taddio
    University of Toronto, Leslie Dan Faculty of Pharmacy, Toronto, Ontario, Canada
    Pediatrics 123:e425-9. 2009
    ..Our objective was to determine the effect of sucrose analgesia for procedural pain on infant pain responses during a subsequent caregiving procedure...
  13. doi request reprint Variability in clinical practice guidelines for sweetening agents in newborn infants undergoing painful procedures
    Anna Taddio
    Department of Pharmacy Practice, Leslie Dan Faculty of Pharmacy, University of Toronto, Ontario, Canada
    Clin J Pain 25:153-5. 2009
    ..The objective of this study was to investigate unit-specific protocols for the use of sweetening agents...
  14. doi request reprint Safety of morphine in nonintubated infants in the neonatal intensive care unit
    Anna Taddio
    Pharmacy Practice Division, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada
    Clin J Pain 25:418-22. 2009
    ..To determine the safety of morphine for procedural pain management in nonintubated infants in the neonatal intensive care unit...
  15. doi request reprint Effect of liposomal lidocaine and sucrose alone and in combination for venipuncture pain in newborns
    Anna Taddio
    Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College St, Toronto, Ontario, Canada M5S 3M2
    Pediatrics 127:e940-7. 2011
    ..To determine the relative effectiveness of liposomal lidocaine, sucrose, and their combination for reducing pain in term newborns...
  16. doi request reprint Influence of repeated painful procedures and sucrose analgesia on the development of hyperalgesia in newborn infants
    Anna Taddio
    Pharmacy Practice Division, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada
    Pain 144:43-8. 2009
    ..In conclusion, sucrose analgesia for repeated painful procedures in the first day of life does not prevent development of remote hyperalgesia in newborns...
  17. doi request reprint Effectiveness and tolerability of pharmacologic and combined interventions for reducing injection pain during routine childhood immunizations: systematic review and meta-analyses
    Vibhuti Shah
    Department of Paediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Clin Ther 31:S104-51. 2009
    ..To date, no systematic review has been published on the effectiveness of pharmacologic and combined interventions for reducing injection pain...
  18. ncbi request reprint Routine immunization practices: use of topical anesthetics and oral analgesics
    Anna Taddio
    Department of Pharmacy, Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada M5G 1X8
    Pediatrics 120:e637-43. 2007
    ..Our objective was to evaluate analgesic use during childhood immunization...
  19. doi request reprint Topical amethocaine gel 4% for intramuscular injection in term neonates: a double-blind, placebo-controlled, randomized trial
    Vibhuti S Shah
    Department of Paediatrics, Mount Sinai Hospital, Toronto, Ontario, Canada
    Clin Ther 30:166-74. 2008
    ..They have been found to attenuate pain from various procedures, including intramuscular (i.m.) injection of vaccines. Published data on their effectiveness for i.m. injection of vitamin K in neonates were not identified...
  20. ncbi request reprint Intravenous morphine and topical tetracaine for treatment of pain in [corrected] neonates undergoing central line placement
    Anna Taddio
    Department of Pharmacy, The Hospital for Sick Children, Faculty of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario
    JAMA 295:793-800. 2006
    ..There is limited evidence of the analgesic effectiveness of opioid analgesia or topical anesthesia during central line placement in neonates, and there are no previous studies of their relative effectiveness...
  21. ncbi request reprint Tobramycin pharmacokinetics in children with febrile neutropenia undergoing stem cell transplantation: once-daily versus thrice-daily administration
    L Lee Dupuis
    Department of Pharmacy, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pharmacotherapy 24:564-73. 2004
    ....
  22. doi request reprint Order of vaccine injection and infant pain response
    Moshe Ipp
    Department of Paediatrics, Paediatric Outcomes Research Team, Division of Paediatric Medicine, The Hospital for Sick Children Research Institute, University of Toronto, 555 University Ave, Toronto, ON M5G 1X8, Canada
    Arch Pediatr Adolesc Med 163:469-72. 2009
    ....
  23. ncbi request reprint Topical 4% amethocaine gel reduces the pain of subcutaneous measles-mumps-rubella vaccination
    Lisa O'Brien
    Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatrics 114:e720-4. 2004
    ..The objective of this study was to assess the efficacy and safety of 4% amethocaine in reducing the pain of subcutaneous measles-mumps-rubella vaccination in 1-year-old infants...
  24. doi request reprint Comparison of pain during two methods of urine collection in preterm infants
    Walid El-Naggar
    Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada
    Pediatrics 125:1224-9. 2010
    ..Suprapubic aspiration (SPA) and urine catheterization (UC) are performed frequently in preterm neonates to rule out urinary tract infection; however, a comparison of the pain caused by both procedures has not been made previously...
  25. pmc Liposomal lidocaine to improve procedural success rates and reduce procedural pain among children: a randomized controlled trial
    Anna Taddio
    The Department of Pharmacy and the Research Institute, The Hospital for Sick Children, Toronto, Ont
    CMAJ 172:1691-5. 2005
    ..We sought to determine the success rate of cannulation, analgesic effectiveness, procedure duration and rate of adverse skin reactions when liposomal lidocaine is used before intravenous cannulation of children...
  26. ncbi request reprint Effects of age, gender and holding on pain response during infant immunization
    Moshe Ipp
    Department of Paediatrics, The Hospital for Sick Children, Toronto, Canada
    Can J Clin Pharmacol 11:e2-7. 2004
    ..Similarly gender did not affect pain response. In contrast, 2-month-old infants displayed more pain during immunization than did 4 or 6-month-old infants...
  27. ncbi request reprint Hair cortisol as a potential biologic marker of chronic stress in hospitalized neonates
    Janet Yamada
    Faculties of Nursing and Medicine, University of Toronto, Toronto, Ont, Canada
    Neonatology 92:42-9. 2007
    ..As preterm and term infants in the neonatal intensive care unit (NICU) undergo multiple stressful/painful procedures, research is required that addresses chronic stress...
  28. ncbi request reprint Contact dermatitis and bradycardia in a preterm infant given tetracaine 4% gel
    Anna Taddio
    Department of Pharmacy and Population Health Sciences, The Hospital for Sick Children, Toronto, Canada
    Ther Drug Monit 28:291-4. 2006
    ..This is the first report of a serious skin reaction in a neonate treated with tetracaine. Based on these findings, tetracaine gel can continue to be used to treat pain in neonates with careful evaluation of the skin...
  29. ncbi request reprint Conditioning and hyperalgesia in newborns exposed to repeated heel lances
    Anna Taddio
    Department of Pharmacy, The Hospital for Sick Children, 555 University Ave, Toronto, Ontario, Canada M5G 1X8
    JAMA 288:857-61. 2002
    ..Hospitalized infants undergo repeated invasive procedures. It is unknown whether cumulative experiences with pain lead to anticipatory pain behaviors and hyperalgesia...
  30. pmc Vaccine-related pain: randomised controlled trial of two injection techniques
    Moshe Ipp
    Division of Pediatric Medicine and Pediatric Outcomes Research Team PORT, Department of Pediatrics, Faculty of Medicine, University of Toronto, Canada
    Arch Dis Child 92:1105-8. 2007
    ..To compare acute pain response during immunisation in infants using a slow standard of care injection technique versus a rapid pragmatic technique...
  31. doi request reprint CYP2D6 polymorphisms and codeine analgesia in postpartum pain management: a pilot study
    Sondra vanderVaart
    Department of Pharmaceutical Sciences, University of Toronto, Ontario, Canada
    Ther Drug Monit 33:425-32. 2011
    ..In contrast, poor metabolizers (PMs), individuals who have no active CYP2D6 genes, convert almost no codeine into morphine and as a result may take multiple doses of codeine without attaining analgesia...
  32. ncbi request reprint A critical review of the topical local anesthetic amethocaine (Ametop) for pediatric pain
    Lisa O'Brien
    Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, Toronto, Ontario, Canada
    Paediatr Drugs 7:41-54. 2005
    ....
  33. ncbi request reprint Beta-endorphin concentration after administration of sucrose in preterm infants
    Anna Taddio
    Department of Pharmacy and Population Health Sciences, Research Institute, The Hospital for Sick Children, and Graduate Faculty of Pharmaceutical Sciences, University of Toronto, Canada
    Arch Pediatr Adolesc Med 157:1071-4. 2003
    ..Sucrose is an effective analgesic for procedural pain in preterm infants. It has been hypothesized that its analgesic effects are mediated by the release of endogenous opioid neurotransmitters such as beta-endorphin...
  34. ncbi request reprint Evaluation of a new lancet device (BD QuikHeel) on pain response and success of procedure in term neonates
    Vibhuti Shah
    Department of Paediatrics and Nursing, Mount Sinai Hospital, Toronto, Ontario, Canada
    Arch Pediatr Adolesc Med 157:1075-8. 2003
    ..To evaluate 2 heel lancet devices in terms of pain response and success of the procedure in neonates undergoing the newborn screening test...
  35. doi request reprint A systematic review of measures for reducing injection pain during adult immunization
    Mary Ellen Hogan
    Graduate Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, Toronto, Ontario, Canada
    Vaccine 28:1514-21. 2010
    ..To evaluate the effectiveness of different pain-relieving interventions to reduce pain from immunization in adults...
  36. doi request reprint The premature infant pain profile: evaluation 13 years after development
    Bonnie Stevens
    Lawrence S Bloomberg Faculty of Nursing and Faculty of Medicine, University of Toronto, Toronto, ON, Canada
    Clin J Pain 26:813-30. 2010
    ..To review the (1) reliability, validation, feasibility, and clinical utility and (2) the use of the Premature Infant Pain Profile (PIPP) from 1996 to 2009 to determine the effectiveness of pain management strategies...
  37. pmc Epidemiology and management of painful procedures in children in Canadian hospitals
    Bonnie J Stevens
    The Hospital for Sick Children, Toronto, Ont
    CMAJ 183:E403-10. 2011
    ....
  38. ncbi request reprint The effectiveness of Proctofoam-HC for treatment of hemorrhoids in late pregnancy
    Sabina Vohra
    The Motherisk Program, Hospital for Sick Children, Toronto, ON, Canada
    J Obstet Gynaecol Can 31:654-9. 2009
    ..Currently no topical anti-hemorrhoidal agents have been studied for effectiveness in pregnancy. This study evaluated the effectiveness of Proctofoam-HC used during the last trimester of pregnancy...
  39. pmc The effect of distant reiki on pain in women after elective Caesarean section: a double-blinded randomised controlled trial
    Sondra vanderVaart
    Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada
    BMJ Open 1:e000021. 2011
    ..4±9.7 mm Hg vs 111.9±11.0 mm Hg, p=0.02) post surgery. Conclusion Distant reiki had no significant effect on pain following an elective C-section. Clinical Trial Registration Number ISRCTN79265996...
  40. ncbi request reprint The effects of early pain experience in neonates on pain responses in infancy and childhood
    Anna Taddio
    Department of Pharmacy and Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
    Paediatr Drugs 7:245-57. 2005
    ..The precise determinants of these changes, their extent, and their permanence are not known but they appear to involve noxious stimulus-induced peripheral and central sensitization, as well as classical conditioning...
  41. ncbi request reprint Lidocaine-prilocaine cream versus tetracaine gel for procedural pain in children
    Anna Taddio
    Department of Pharmacy, The Hospital for Sick Children, Toronto, Ontario, Canada
    Ann Pharmacother 36:687-92. 2002
    ..To determine the relative efficacy of lidocaine-prilocaine and tetracaine for procedural pain in children...
  42. ncbi request reprint Pain, opioid tolerance and sensitisation to nociception in the neonate
    Anna Taddio
    Department of Population Health Sciences, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
    Best Pract Res Clin Anaesthesiol 18:291-302. 2004
    ..Recent studies have demonstrated that untreated pain can have long-term effects on infant pain behaviours months beyond the events, thus, opioid analgesics may have a beneficial role that extends beyond the immediate painful event(s)...
  43. doi request reprint Systematic review and meta-analysis of the effect of warming local anesthetics on injection pain
    Mary Ellen Hogan
    Graduate Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
    Ann Emerg Med 58:86-98.e1. 2011
    ..We determine the effectiveness of warming local anesthetics to reduce pain in adults and children undergoing local anesthetic infiltration into intradermal or subcutaneous tissue...
  44. ncbi request reprint Caregivers' responses to pain in their children in the emergency department
    Ryan W Smith
    Graduate Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Toronto, Ontario, Canada
    Arch Pediatr Adolesc Med 161:578-82. 2007
    ..To explore physiological and anxiety responses of caregivers who witness a venipuncture being performed on their child and the effects of caregivers' responses on child pain and distress...
  45. doi request reprint A randomized control trial comparing immunogenicity, safety, and preference for self- versus nurse-administered intradermal influenza vaccine
    Brenda L Coleman
    Mount Sinai Hospital, Department of Microbiology, Toronto, Canada
    Vaccine 30:6287-93. 2012
    ..Intradermally administered influenza vaccine is as immunogenic as intramuscular vaccine at a lower unit dose. New microinjection systems could allow self-administration of vaccine, potentially reducing the cost and inconvenience...
  46. doi request reprint Intravenous midazolam infusion for sedation of infants in the neonatal intensive care unit
    Eugene Ng
    Aubrey andMarla Dan ProgramforHigh RiskMothers and Babies, SunnybrookHealth Sciences Centre, Toronto, Canada
    Cochrane Database Syst Rev 6:CD002052. 2012
    ..Midazolam is a short-acting benzodiazepine that is increasingly used in neonatal intensive care units (NICU). However, its effectiveness as a sedative in neonates has not been systematically evaluated...
  47. ncbi request reprint Opioid analgesia for infants in the neonatal intensive care unit
    Anna Taddio
    Neonatal Intensive Care Unit, Research Institute, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada
    Clin Perinatol 29:493-509. 2002
    ..Further research is needed to determine how to optimize their effects. Data on the long-term effects of neonatal opioid exposure are warranted...
  48. doi request reprint Safety and efficacy of ketorolac in children after cardiac surgery
    Miho Inoue
    Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
    Intensive Care Med 35:1584-92. 2009
    ..To evaluate the nephrotoxic and opioid-sparing effects of ketorolac in children after cardiac surgery...
  49. pmc Effect of iron content on the tolerability of prenatal multivitamins in pregnancy
    Patricia Nguyen
    Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada
    BMC Pregnancy Childbirth 8:17. 2008
    ....
  50. doi request reprint Nonpharmacological management of pain during common needle puncture procedures in infants: current research evidence and practical considerations
    Carol McNair
    Nursing, The Hospital for Sick Children, Toronto, Ontario, Canada Child Health Evaluative Sciences, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada
    Clin Perinatol 40:493-508. 2013
    ....
  51. doi request reprint Pharmacology of milrinone in neonates with persistent pulmonary hypertension of the newborn and suboptimal response to inhaled nitric oxide
    Patrick J McNamara
    Departments of Pediatrics, University of Toronto, Toronto, Canada
    Pediatr Crit Care Med 14:74-84. 2013
    ..The primary objective was to investigate the pharmacological profile of milrinone in persistent pulmonary hypertension of the newborn. Secondary objectives were to delineate short-term outcomes and safety profile...
  52. ncbi request reprint Cyclosporine excretion into breast milk
    Myla E Moretti
    The Motherisk Program, The Hospital for Sick Children, Toronto, Ontario, Canada
    Transplantation 75:2144-6. 2003
    ..We show a wide range of infant exposures to the drug in milk, noting that one of the infants had therapeutic blood concentrations of cyclosporine despite relatively low concentrations of the drug in milk...
  53. ncbi request reprint Prevalence of depression during pregnancy: systematic review
    Heather A Bennett
    Faculty of Pharmacy and Department of Medicine, University of Toronto, Ontario, Canada
    Obstet Gynecol 103:698-709. 2004
    ....
  54. pmc Benchmarking pain outcomes for children with sickle cell disease hospitalized in a tertiary referral pediatric hospital
    Abi Vijenthira
    Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pain Res Manag 17:291-6. 2012
    ..Painful vaso-occlusive crisis (VOC) is the most common reason for hospitalization in children with sickle cell disease...
  55. pmc Practices and perceptions regarding pain and pain management during routine childhood immunizations: Findings from a focus-group study with nurses working at Toronto Public Health, Ontario
    Andrew Kikuta
    Graduate Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto
    Can J Infect Dis Med Microbiol 22:43-8. 2011
    ..Nurses in public health administer a substantial number of injections; however, their attitudes and practices surrounding acute pain during vaccine injections have not been previously explored...
  56. pmc Mothers' beliefs about analgesia during childhood immunization
    Elena Parvez
    Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario
    Paediatr Child Health 15:289-93. 2010
    ....
  57. ncbi request reprint Acetaminophen and ibuprofen for prevention of adverse reactions associated with childhood immunization
    Jennifer Manley
    Graduate Department of Pharmaceutical Sciences, University of Toronto, Ontario, Canada
    Ann Pharmacother 41:1227-32. 2007
    ..To evaluate the literature examining prophylactic use of acetaminophen and ibuprofen for prevention of adverse reactions associated with childhood immunization...
  58. ncbi request reprint Safety of benzodiazepines in newborns
    Eugene Ng
    Department of Newborn and Developmental Paediatrics, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Ann Pharmacother 36:1150-5. 2002
    ..Benzodiazepines are being used in neonatal intensive care units for sedation and control of seizures. However, anecdotal reports suggest that their use in infants may be associated with serious adverse effects (AEs)...
  59. ncbi request reprint Development and validation of the pediatric nausea assessment tool for use in children receiving antineoplastic agents
    L Lee Dupuis
    Department of Pharmacy, Divisions of Haematology Oncology, Population Health Sciences, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada
    Pharmacotherapy 26:1221-31. 2006
    ..To develop and validate an instrument to assess nausea intensity in children aged 4-18 years...
  60. ncbi request reprint Randomized controlled trial of once- versus thrice-daily tobramycin in febrile neutropenic children undergoing stem cell transplantation
    Lillian Sung
    Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada
    J Natl Cancer Inst 95:1869-77. 2003
    ..In particular, the relative nephrotoxicity and efficacy of tobramycin administered as a single daily dose or as three daily doses among this patient population is not known...
  61. doi request reprint Gabapentin improves postcesarean delivery pain management: a randomized, placebo-controlled trial
    ALBERT MOORE
    Department of Anesthesia and Pain Management, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
    Anesth Analg 112:167-73. 2011
    ..Gabapentin is effective for preventing and treating acute and chronic postoperative pain; however, it has not been described for use in cesarean delivery. We hypothesized that preoperative gabapentin would reduce postcesarean delivery pain...
  62. ncbi request reprint Summary proceedings from the neonatal pain-control group
    Kanwaljeet J S Anand
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Pediatrics 117:S9-S22. 2006
    ..Full-length articles on procedural pain, sedation and analgesia for ventilated infants, perioperative pain, and study designs for neonatal pain research were published in Clinical Therapeutics (June 2005)...
  63. ncbi request reprint Topical anesthesia in neonates: clinical practices and practical considerations
    Victoria Tutag Lehr
    Department of Pharmacy Practice, The Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Division of Clinical Pharmacology and Toxicology, Children s Hospital of Michigan, Detroit, MI, USA
    Semin Perinatol 31:323-9. 2007
    ..This review seeks to expand the options for topical anesthesia in neonates...
  64. ncbi request reprint Analgesia and local anesthesia during invasive procedures in the neonate
    K J S Anand
    Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, USA
    Clin Ther 27:844-76. 2005
    ....
  65. ncbi request reprint Analgesia and anesthesia for neonates: study design and ethical issues
    K J S Anand
    Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, USA
    Clin Ther 27:814-43. 2005
    ....