Research Topics
| J R StinchcombeSummaryAffiliation: University of Toronto Country: Canada Publications
| Collaborators
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Detail Information
Publications
Genetics and evolution of function-valued traits: understanding environmentally responsive phenotypesJohn R Stinchcombe
Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, M5S3B2, Canada
Trends Ecol Evol 27:637-47. 2012..We also illustrate applications of function-valued methods to address ecological, evolutionary, and behavioral hypotheses, and highlight future directions...- Across-environment genetic correlations and the frequency of selective environments shape the evolutionary dynamics of growth rate in Impatiens capensisJohn R Stinchcombe
Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, Ontario, Canada
Evolution 64:2887-903. 2010..Our results highlight the importance of considering both the frequency of selective environments and the across-environment genetic covariances in traits simultaneously... - Estimating nonlinear selection gradients using quadratic regression coefficients: double or nothing?John R Stinchcombe
Department of Ecology and Evolutionary Biology, and Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, ON M5S 3B2, Canada
Evolution 62:2435-40. 2008..Proper treatment of quadratic regression coefficients is necessary for estimation of fitness surfaces and contour plots, canonical analysis of the gamma matrix, and modeling the evolution of populations on an adaptive landscape... 
Combining population genomics and quantitative genetics: finding the genes underlying ecologically important traitsJ R Stinchcombe
Department of Ecology and Evolutionary Biology, Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, Ontario, Canada
Heredity (Edinb) 100:158-70. 2008..Specifically, we discuss advantages and limitations of each method and argue that a combination of the two provides a powerful approach to uncovering the molecular mechanisms responsible for adaptation...
Polymorphic genes of major effect: consequences for variation, selection and evolution in Arabidopsis thalianaJohn R Stinchcombe
Department of Ecology and Evolutionary Biology, Unversity of Toronto, Toronto, Ontario
Genetics 182:911-22. 2009..To compare responses to selection between allele classes, we developed a resampling strategy that incorporates uncertainty in estimates of selection that can also be used for statistical comparisons of G matrices...- An emerging synthesis between community ecology and evolutionary biologyMarc T J Johnson
Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, M5S 3B2, Canada
Trends Ecol Evol 22:250-7. 2007..Answering this question will have important implications for both basic and applied problems in biology... - How much do genetic covariances alter the rate of adaptation?Aneil F Agrawal
Department of Ecology and Evolutionary Biology, University of Toronto, 25 Willcocks Street, Toronto, Ontario, Canada M5S 3B2
Proc Biol Sci 276:1183-91. 2009..We also discuss how our metric can be used to identify traits or suites of traits whose genetic covariances to other traits have a particularly large impact on the rate of adaptation... - Discordant longitudinal clines in flowering time and phytochrome C in Arabidopsis thalianaKaren E Samis
Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, Canada
Evolution 62:2971-83. 2008.... - Interspecific competition alters natural selection on shade avoidance phenotypes in Impatiens capensisBrechann V McGoey
Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, Canada
New Phytol 183:880-91. 2009.... - A latitudinal cline in flowering time in Arabidopsis thaliana modulated by the flowering time gene FRIGIDAJohn R Stinchcombe
Department of Ecology and Evolutionary Biology, Brown University, Box G W, Providence, RI 02912, USA
Proc Natl Acad Sci U S A 101:4712-7. 2004..More generally, our results indicate that by combining ecological and molecular genetic data, it is possible to understand the forces acting on life history transitions at the level of specific loci... - Environmental dependency in the expression of costs of tolerance to deer herbivoryJohn R Stinchcombe
Biology Department, Duke University, Durham, North Carolina 27708, USA
Evolution 56:1063-7. 2002..However, these costs were detected only in the presence of insect herbivores. Such environmental dependency in the expression of costs of tolerance may facilitate the maintenance of tolerance at intermediate levels... - QTL architecture of resistance and tolerance traits in Arabidopsis thaliana in natural environmentsCynthia Weinig
Department of Ecology and Evolutionary Biology Box G W, Brown University, Providence, RI 02912, USA
Mol Ecol 12:1153-63. 2003..Our results show how linking molecular-genetic tools with field studies in ecologically relevant settings can clarify the role of specific loci in the evolution of quantitative traits... - A latitudinal cline and response to vernalization in leaf angle and morphology in Arabidopsis thaliana (Brassicaceae)Robin Hopkins
Ecology and Evolutionary Biology, Brown University, Providence, RI, USA
New Phytol 179:155-64. 2008..As predicted by functional and adaptive hypotheses, our results show genetically based clinal variation as well as environmentally induced variation in leaf traits... - Fitness effects associated with the major flowering time gene FRIGIDA in Arabidopsis thaliana in the fieldTonia M Korves
Department of Ecology and Evolutionary Biology, Brown University, Providence, Rhode Island 02912, USA
Am Nat 169:E141-57. 2007.... - Evolutionary genetics of resistance and tolerance to natural herbivory in Arabidopsis thalianaCynthia Weinig
Department of Ecology and Evolutionary Biology, Box G W, Brown University, Providence, Rhode Island 02912, USA
Evolution 57:1270-80. 2003..These observations are consistent with the hypothesis that selection may act to maintain resistance and tolerance at intermediate levels in spatially or temporally varying environments or those with varying herbivore populations... - Ecosystem engineers as selective agents: the effects of leaf litter on emergence time and early growth in Impatiens capensisJohn R Stinchcombe
Ecol Lett 9:258-70. 2006..More generally, our results demonstrate the potential for ecosystem engineers to alter both the ecological and the evolutionary dynamics of the species they affect... - Epistatic interaction between Arabidopsis FRI and FLC flowering time genes generates a latitudinal cline in a life history traitAna L Caicedo
Genetics Department, North Carolina State University, Raleigh, NC 27695, USA
Proc Natl Acad Sci U S A 101:15670-5. 2004.... - Linkage disequilibrium mapping of Arabidopsis CRY2 flowering time allelesKenneth M Olsen
Department of Genetics, North Carolina State University, Raleigh, North Carolina 27695, USA
Genetics 167:1361-9. 2004..This study demonstrates the utility of LD mapping for elucidating the genetic basis of natural, ecologically relevant variation in Arabidopsis... - The evolution of tolerance to deer herbivory: modifications caused by the abundance of insect herbivoresJohn R Stinchcombe
Ecology, Evolution and Organismal Biology Group, Biology Department, Duke University, Durham, NC 27708, USA
Proc Biol Sci 269:1241-6. 2002..These results indicate that variation in community composition may be a driving force in generating geographical mosaics...