J R Stinchcombe

Summary

Affiliation: University of Toronto
Country: Canada

Publications

  1. doi request reprint Estimating uncertainty in multivariate responses to selection
    John R Stinchcombe
    Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, Ontario, M5S3B2, Canada Centre for Genome Evolution and Function, University of Toronto, Toronto, Ontario, M5S3B2, Canada
    Evolution 68:1188-96. 2014
  2. doi request reprint Genetics and evolution of function-valued traits: understanding environmentally responsive phenotypes
    John R Stinchcombe
    Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, M5S3B2, Canada
    Trends Ecol Evol 27:637-47. 2012
  3. doi request reprint Across-environment genetic correlations and the frequency of selective environments shape the evolutionary dynamics of growth rate in Impatiens capensis
    John R Stinchcombe
    Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, Ontario, Canada
    Evolution 64:2887-903. 2010
  4. ncbi request reprint Combining population genomics and quantitative genetics: finding the genes underlying ecologically important traits
    J R Stinchcombe
    Department of Ecology and Evolutionary Biology, Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, Ontario, Canada
    Heredity (Edinb) 100:158-70. 2008
  5. doi request reprint Estimating nonlinear selection gradients using quadratic regression coefficients: double or nothing?
    John R Stinchcombe
    Department of Ecology and Evolutionary Biology, and Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, ON M5S 3B2, Canada
    Evolution 62:2435-40. 2008
  6. ncbi request reprint An emerging synthesis between community ecology and evolutionary biology
    Marc T J Johnson
    Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, M5S 3B2, Canada
    Trends Ecol Evol 22:250-7. 2007
  7. doi request reprint Discordant longitudinal clines in flowering time and phytochrome C in Arabidopsis thaliana
    Karen E Samis
    Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, Canada
    Evolution 62:2971-83. 2008
  8. pmc How much do genetic covariances alter the rate of adaptation?
    Aneil F Agrawal
    Department of Ecology and Evolutionary Biology, University of Toronto, 25 Willcocks Street, Toronto, Ontario, Canada M5S 3B2
    Proc Biol Sci 276:1183-91. 2009
  9. pmc Polymorphic genes of major effect: consequences for variation, selection and evolution in Arabidopsis thaliana
    John R Stinchcombe
    Department of Ecology and Evolutionary Biology, Unversity of Toronto, Toronto, Ontario
    Genetics 182:911-22. 2009
  10. doi request reprint Interspecific competition alters natural selection on shade avoidance phenotypes in Impatiens capensis
    Brechann V McGoey
    Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, Canada
    New Phytol 183:880-91. 2009

Detail Information

Publications20

  1. doi request reprint Estimating uncertainty in multivariate responses to selection
    John R Stinchcombe
    Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, Ontario, M5S3B2, Canada Centre for Genome Evolution and Function, University of Toronto, Toronto, Ontario, M5S3B2, Canada
    Evolution 68:1188-96. 2014
    ..More generally, we suggest that applying both the Robertson-Price Identity and the multivariate breeder's equation will facilitate hypothesis testing about natural selection, genetic constraints, and evolutionary responses. ..
  2. doi request reprint Genetics and evolution of function-valued traits: understanding environmentally responsive phenotypes
    John R Stinchcombe
    Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, M5S3B2, Canada
    Trends Ecol Evol 27:637-47. 2012
    ..We also illustrate applications of function-valued methods to address ecological, evolutionary, and behavioral hypotheses, and highlight future directions...
  3. doi request reprint Across-environment genetic correlations and the frequency of selective environments shape the evolutionary dynamics of growth rate in Impatiens capensis
    John R Stinchcombe
    Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, Ontario, Canada
    Evolution 64:2887-903. 2010
    ..Our results highlight the importance of considering both the frequency of selective environments and the across-environment genetic covariances in traits simultaneously...
  4. ncbi request reprint Combining population genomics and quantitative genetics: finding the genes underlying ecologically important traits
    J R Stinchcombe
    Department of Ecology and Evolutionary Biology, Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, Ontario, Canada
    Heredity (Edinb) 100:158-70. 2008
    ..Specifically, we discuss advantages and limitations of each method and argue that a combination of the two provides a powerful approach to uncovering the molecular mechanisms responsible for adaptation...
  5. doi request reprint Estimating nonlinear selection gradients using quadratic regression coefficients: double or nothing?
    John R Stinchcombe
    Department of Ecology and Evolutionary Biology, and Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, ON M5S 3B2, Canada
    Evolution 62:2435-40. 2008
    ..Proper treatment of quadratic regression coefficients is necessary for estimation of fitness surfaces and contour plots, canonical analysis of the gamma matrix, and modeling the evolution of populations on an adaptive landscape...
  6. ncbi request reprint An emerging synthesis between community ecology and evolutionary biology
    Marc T J Johnson
    Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, M5S 3B2, Canada
    Trends Ecol Evol 22:250-7. 2007
    ..Answering this question will have important implications for both basic and applied problems in biology...
  7. doi request reprint Discordant longitudinal clines in flowering time and phytochrome C in Arabidopsis thaliana
    Karen E Samis
    Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, Canada
    Evolution 62:2971-83. 2008
    ....
  8. pmc How much do genetic covariances alter the rate of adaptation?
    Aneil F Agrawal
    Department of Ecology and Evolutionary Biology, University of Toronto, 25 Willcocks Street, Toronto, Ontario, Canada M5S 3B2
    Proc Biol Sci 276:1183-91. 2009
    ..We also discuss how our metric can be used to identify traits or suites of traits whose genetic covariances to other traits have a particularly large impact on the rate of adaptation...
  9. pmc Polymorphic genes of major effect: consequences for variation, selection and evolution in Arabidopsis thaliana
    John R Stinchcombe
    Department of Ecology and Evolutionary Biology, Unversity of Toronto, Toronto, Ontario
    Genetics 182:911-22. 2009
    ..To compare responses to selection between allele classes, we developed a resampling strategy that incorporates uncertainty in estimates of selection that can also be used for statistical comparisons of G matrices...
  10. doi request reprint Interspecific competition alters natural selection on shade avoidance phenotypes in Impatiens capensis
    Brechann V McGoey
    Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON, Canada
    New Phytol 183:880-91. 2009
    ....
  11. doi request reprint A latitudinal cline and response to vernalization in leaf angle and morphology in Arabidopsis thaliana (Brassicaceae)
    Robin Hopkins
    Ecology and Evolutionary Biology, Brown University, Providence, RI, USA
    New Phytol 179:155-64. 2008
    ..As predicted by functional and adaptive hypotheses, our results show genetically based clinal variation as well as environmentally induced variation in leaf traits...
  12. ncbi request reprint Fitness effects associated with the major flowering time gene FRIGIDA in Arabidopsis thaliana in the field
    Tonia M Korves
    Department of Ecology and Evolutionary Biology, Brown University, Providence, Rhode Island 02912, USA
    Am Nat 169:E141-57. 2007
    ....
  13. ncbi request reprint Ecosystem engineers as selective agents: the effects of leaf litter on emergence time and early growth in Impatiens capensis
    John R Stinchcombe
    Ecol Lett 9:258-70. 2006
    ..More generally, our results demonstrate the potential for ecosystem engineers to alter both the ecological and the evolutionary dynamics of the species they affect...
  14. pmc Epistatic interaction between Arabidopsis FRI and FLC flowering time genes generates a latitudinal cline in a life history trait
    Ana L Caicedo
    Genetics Department, North Carolina State University, Raleigh, NC 27695, USA
    Proc Natl Acad Sci U S A 101:15670-5. 2004
    ....
  15. pmc Linkage disequilibrium mapping of Arabidopsis CRY2 flowering time alleles
    Kenneth M Olsen
    Department of Genetics, North Carolina State University, Raleigh, North Carolina 27695, USA
    Genetics 167:1361-9. 2004
    ..This study demonstrates the utility of LD mapping for elucidating the genetic basis of natural, ecologically relevant variation in Arabidopsis...
  16. pmc A latitudinal cline in flowering time in Arabidopsis thaliana modulated by the flowering time gene FRIGIDA
    John R Stinchcombe
    Department of Ecology and Evolutionary Biology, Brown University, Box G W, Providence, RI 02912, USA
    Proc Natl Acad Sci U S A 101:4712-7. 2004
    ..More generally, our results indicate that by combining ecological and molecular genetic data, it is possible to understand the forces acting on life history transitions at the level of specific loci...
  17. ncbi request reprint Evolutionary genetics of resistance and tolerance to natural herbivory in Arabidopsis thaliana
    Cynthia Weinig
    Department of Ecology and Evolutionary Biology, Box G W, Brown University, Providence, Rhode Island 02912, USA
    Evolution 57:1270-80. 2003
    ..These observations are consistent with the hypothesis that selection may act to maintain resistance and tolerance at intermediate levels in spatially or temporally varying environments or those with varying herbivore populations...
  18. ncbi request reprint QTL architecture of resistance and tolerance traits in Arabidopsis thaliana in natural environments
    Cynthia Weinig
    Department of Ecology and Evolutionary Biology Box G W, Brown University, Providence, RI 02912, USA
    Mol Ecol 12:1153-63. 2003
    ..Our results show how linking molecular-genetic tools with field studies in ecologically relevant settings can clarify the role of specific loci in the evolution of quantitative traits...
  19. ncbi request reprint Environmental dependency in the expression of costs of tolerance to deer herbivory
    John R Stinchcombe
    Biology Department, Duke University, Durham, North Carolina 27708, USA
    Evolution 56:1063-7. 2002
    ..However, these costs were detected only in the presence of insect herbivores. Such environmental dependency in the expression of costs of tolerance may facilitate the maintenance of tolerance at intermediate levels...
  20. pmc The evolution of tolerance to deer herbivory: modifications caused by the abundance of insect herbivores
    John R Stinchcombe
    Ecology, Evolution and Organismal Biology Group, Biology Department, Duke University, Durham, NC 27708, USA
    Proc Biol Sci 269:1241-6. 2002
    ..These results indicate that variation in community composition may be a driving force in generating geographical mosaics...