Michael K Stickland
Affiliation: University of Alberta
Stickland M, Morgan B, Dempsey J. Carotid chemoreceptor modulation of sympathetic vasoconstrictor outflow during exercise in healthy humans. J Physiol. 2008;586:1743-54 pubmed publisher
..Consistent with previous animal work, these data indicate that the CC contributes to exercise-induced increases in sympathetic vasoconstrictor outflow. ..
Tedjasaputra V, van Diepen S, Phillips D, Wong E, Bhutani M, Michaelchuk W, et al
. Pulmonary capillary blood volume response to exercise is diminished in mild chronic obstructive pulmonary disease. Respir Med. 2018;145:57-65 pubmed publisher
..Despite relatively minor airflow obstruction, mild COPD patients exhibit a diminished DLCO and capillary blood volume response to exercise, which appears to contribute to ventilatory inefficiency and greater dyspnea. ..
Stickland M, Miller J, Smith C, Dempsey J. Carotid chemoreceptor modulation of regional blood flow distribution during exercise in health and chronic heart failure. Circ Res. 2007;100:1371-8 pubmed
..These results establish an important role for the CCs in cardiovascular control in the healthy animal during exercise and in the CHF animal both at rest and during exercise. ..
Edgell H, McMurtry M, Haykowsky M, Paterson I, Ezekowitz J, Dyck J, et al
. Peripheral chemoreceptor control of cardiovascular function at rest and during exercise in heart failure patients. J Appl Physiol (1985). 2015;118:839-48 pubmed publisher
..004), but decreased in HF (P = 0.02). Our findings indicate that the peripheral chemoreceptor contributes to cardiovascular control at rest in HF patients and during exercise in risk-matched controls. ..
Stickland M, Fuhr D, Haykowsky M, Jones K, Paterson D, Ezekowitz J, et al
. Carotid chemoreceptor modulation of blood flow during exercise in healthy humans. J Physiol. 2011;589:6219-30 pubmed publisher
..These findings indicate that the carotid chemoreceptor contributes to skeletal muscle blood flow regulation during normoxic exercise in healthy humans, but that the influence of the CC on blood flow regulation in hypoxia is limited. ..
Bouwsema M, Tedjasaputra V, Stickland M. Are there sex differences in the capillary blood volume and diffusing capacity response to exercise?. J Appl Physiol (1985). 2017;122:460-469 pubmed publisher
..3 s in either group. After differences in lung volume are accounted for, there is no intrinsic sex difference in DlCO, Vc, or Dm response to exercise. ..
Moore L, Byers B, Fuhr D, Wong E, Bhutani M, Stickland M. Cardiovascular benefits from standard pulmonary rehabilitation are related to baseline exercise tolerance levels in chronic obstructive pulmonary disease. Respir Med. 2017;132:56-61 pubmed publisher
..2 ± 0.6 to 7.3 ± 2.0 m/s, p < 0.05). The PWV response to PR was not influenced by baseline physical activity levels. COPD patients with low exercise tolerance appear to derive the greatest cardiovascular benefits from PR. ..