Poul Hb Sorensen
Affiliation: University of British Columbia
- PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's oncology groupPoul H B Sorensen
Department of Pathology, Children s and Women s Hospital of British Columbia, Vancouver, British Columbia, Canada
J Clin Oncol 20:2672-9. 2002..We wished to confirm the diagnostic specificity of gene fusion detection in a large cohort of RMS patients and to evaluate whether these alterations influence clinical outcome in ARMS...
- Targeting the insulin-like growth factor 1 receptor (IGF1R) signaling pathway for cancer therapyCristina E Tognon
British Columbia Cancer Research Centre, Department of Molecular Oncology, Vancouver, British Columbia, Canada
Expert Opin Ther Targets 16:33-48. 2012..Numerous clinical trials are currently assessing therapies that inhibit either growth factor binding or IGF1R itself. Therapeutic benefit, often in the form of stable disease, has been reported for many different cancer types...
- The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNAPhilipp Kapranov
Helicos BioSciences Corporation, One Kendall Square, Building 700, Cambridge, MA 02139, USA
BMC Biol 8:149. 2010..For example, efforts to elucidate how non-coding RNAs (ncRNAs) regulate genome function will be compromised if that class of RNAs is dismissed as simply 'transcriptional noise'...