K K Soma

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. ncbi request reprint Dehydroepiandrosterone (DHEA) increases territorial song and the size of an associated brain region in a male songbird
    Kiran K Soma
    Department of Zoology, University of Washington, Seattle, Washington 98195, USA
    Horm Behav 41:203-12. 2002
  2. pmc Testosterone and aggression: Berthold, birds and beyond
    K K Soma
    Department of Psychology, Graduate Program in Neuroscience, and Brain Research Centre, University of British Columbia, Vancouver, BC, Canada
    J Neuroendocrinol 18:543-51. 2006
  3. doi request reprint Sex differences in DHEA and estradiol during development in a wild songbird: Jugular versus brachial plasma
    Eunice H Chin
    Department of Zoology, University of British Columbia, 6270 University Blvd, Vancouver, BC, Canada
    Horm Behav 54:194-202. 2008
  4. pmc Neural responses to aggressive challenge correlate with behavior in nonbreeding sparrows
    James L Goodson
    Psychology Department, University of California, San Diego, La Jolla, 92093, USA
    Neuroreport 16:1719-23. 2005
  5. doi request reprint Novel mechanisms for neuroendocrine regulation of aggression
    Kiran K Soma
    Department of Psychology, Graduate Program in Neuroscience, University of British Columbia, Vancouver, BC, Canada V6T 1Z4
    Front Neuroendocrinol 29:476-89. 2008
  6. pmc Aggressive interactions rapidly increase androgen synthesis in the brain during the non-breeding season
    Devaleena S Pradhan
    Department of Zoology, University of British Columbia, Vancouver, BC, Canada V6T 1Z4
    Horm Behav 57:381-9. 2010
  7. doi request reprint Effects of aggressive encounters on plasma corticosteroid-binding globulin and its ligands in white-crowned sparrows
    Thierry D Charlier
    Department of Psychology, University of British Columbia, Vancouver, BC, Canada
    Horm Behav 56:339-47. 2009
  8. pmc Corticosterone and dehydroepiandrosterone in songbird plasma and brain: effects of season and acute stress
    Amy E M Newman
    Department of Psychology, University of British Columbia, Vancouver, BC, Canada
    Eur J Neurosci 29:1905-14. 2009
  9. pmc Dehydroepiandrosterone and corticosterone are regulated by season and acute stress in a wild songbird: jugular versus brachial plasma
    Amy E M Newman
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver, British Columbia, Canada V6T 1Z4
    Endocrinology 149:2537-45. 2008
  10. pmc Neurosteroids and female reproduction: estrogen increases 3beta-HSD mRNA and activity in rat hypothalamus
    K K Soma
    Department of Psychology and Zoology, Graduate Program in Neuroscience, University of British Columbia, Vancouver, Canada
    Endocrinology 146:4386-90. 2005

Detail Information

Publications23

  1. ncbi request reprint Dehydroepiandrosterone (DHEA) increases territorial song and the size of an associated brain region in a male songbird
    Kiran K Soma
    Department of Zoology, University of Washington, Seattle, Washington 98195, USA
    Horm Behav 41:203-12. 2002
    ..The data are consistent with the hypothesis that DHEA regulates territorial behavior, especially in the nonbreeding season, when plasma T is basal...
  2. pmc Testosterone and aggression: Berthold, birds and beyond
    K K Soma
    Department of Psychology, Graduate Program in Neuroscience, and Brain Research Centre, University of British Columbia, Vancouver, BC, Canada
    J Neuroendocrinol 18:543-51. 2006
    ..Recent studies in tropical birds, hamsters, and humans suggest that these neuroendocrine mechanisms are important for the control of aggression in many vertebrate species...
  3. doi request reprint Sex differences in DHEA and estradiol during development in a wild songbird: Jugular versus brachial plasma
    Eunice H Chin
    Department of Zoology, University of British Columbia, 6270 University Blvd, Vancouver, BC, Canada
    Horm Behav 54:194-202. 2008
    ..Taken together, these data suggest that DHEA may play a role in brain sexual differentiation in songbirds...
  4. pmc Neural responses to aggressive challenge correlate with behavior in nonbreeding sparrows
    James L Goodson
    Psychology Department, University of California, San Diego, La Jolla, 92093, USA
    Neuroreport 16:1719-23. 2005
    ..Homologous areas in mammals show greater responses in subordinate subjects than in dominant subjects. Thus, these brain areas may be responsive to social stressors across a wide range of vertebrates...
  5. doi request reprint Novel mechanisms for neuroendocrine regulation of aggression
    Kiran K Soma
    Department of Psychology, Graduate Program in Neuroscience, University of British Columbia, Vancouver, BC, Canada V6T 1Z4
    Front Neuroendocrinol 29:476-89. 2008
    ..g., melatonin) may allow animals to switch from one neuroendocrine mechanism to another across the year. Such mechanisms may be important for the control of aggression in many vertebrate species, including humans...
  6. pmc Aggressive interactions rapidly increase androgen synthesis in the brain during the non-breeding season
    Devaleena S Pradhan
    Department of Zoology, University of British Columbia, Vancouver, BC, Canada V6T 1Z4
    Horm Behav 57:381-9. 2010
    ..Local steroid signaling produces high spatial and temporal specificity of steroid signals and avoids the costs of high systemic T levels during the non-breeding season...
  7. doi request reprint Effects of aggressive encounters on plasma corticosteroid-binding globulin and its ligands in white-crowned sparrows
    Thierry D Charlier
    Department of Psychology, University of British Columbia, Vancouver, BC, Canada
    Horm Behav 56:339-47. 2009
    ..However, this small change is unlikely to increase free testosterone levels, because of the large number of seemingly unoccupied CBG binding sites in these subjects...
  8. pmc Corticosterone and dehydroepiandrosterone in songbird plasma and brain: effects of season and acute stress
    Amy E M Newman
    Department of Psychology, University of British Columbia, Vancouver, BC, Canada
    Eur J Neurosci 29:1905-14. 2009
    ..These results highlight several critical differences between systemic and local steroid concentrations and the difficulty of using circulating steroid levels to infer local steroid levels within the brain...
  9. pmc Dehydroepiandrosterone and corticosterone are regulated by season and acute stress in a wild songbird: jugular versus brachial plasma
    Amy E M Newman
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver, British Columbia, Canada V6T 1Z4
    Endocrinology 149:2537-45. 2008
    ..Furthermore, these results suggest that CORT and DHEA are locally synthesized in the brain during molt, when systemic levels of CORT and DHEA are low...
  10. pmc Neurosteroids and female reproduction: estrogen increases 3beta-HSD mRNA and activity in rat hypothalamus
    K K Soma
    Department of Psychology and Zoology, Graduate Program in Neuroscience, University of British Columbia, Vancouver, Canada
    Endocrinology 146:4386-90. 2005
    ..These data support the hypothesis that PROG is a neurosteroid, produced locally in the hypothalamus from cholesterol, which functions in the estrogen positive-feedback mechanism driving the LH surge...
  11. doi request reprint 3β-HSD in songbird brain: subcellular localization and rapid regulation by estradiol
    Devaleena S Pradhan
    Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada
    J Neurochem 115:667-75. 2010
    ..This is the first study to examine the subcellular localization of 3β-HSD in the brain, and the data demonstrate the importance of subcellular localization for the regulation of steroidogenic enzymes in the brain...
  12. doi request reprint Neurosteroids, immunosteroids, and the Balkanization of endocrinology
    Kim L Schmidt
    Department of Psychology, University of British Columbia, 2136 West Mall, Vancouver, BC, Canada
    Gen Comp Endocrinol 157:266-74. 2008
    ....
  13. doi request reprint Corticosterone and dehydroepiandrosterone have opposing effects on adult neuroplasticity in the avian song control system
    Amy E M Newman
    Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z4
    J Comp Neurol 518:3662-78. 2010
    ..Within brain regions that are particularly vulnerable to corticosterone, such as the songbird HVC and rat hippocampus, DHEA appears to be a potent native antiglucocorticoid...
  14. pmc Rapid estrogen regulation of DHEA metabolism in the male and female songbird brain
    Devaleena S Pradhan
    Department of Zoology, University of British Columbia, Vancouver, British Columbia, Canada
    J Neurochem 104:244-53. 2008
    ..These are the first data to show a rapid effect of estrogens on the songbird brain and suggest that rapid estrogen effects differ between male and female brains...
  15. doi request reprint Plasma DHEA levels in wild, territorial red squirrels: seasonal variation and effect of ACTH
    Rudy Boonstra
    Centre for the Neurobiology of Stress, Department of Biological Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto, Ont, Canada M1C 1A4
    Gen Comp Endocrinol 158:61-7. 2008
    ..These data lay the foundation for future studies on the role of DHEA in non-breeding territoriality in this species and other mammals...
  16. ncbi request reprint Brain aromatase, 5 alpha-reductase, and 5 beta-reductase change seasonally in wild male song sparrows: relationship to aggressive and sexual behavior
    Kiran K Soma
    Department of Physiological Science and Laboratory of Neuroendocrinology of the Brain Research Institute, University of California at Los Angeles, Los Angeles, California 90095, USA
    J Neurobiol 56:209-21. 2003
    ..These data highlight the relevance of neural steroid metabolism to the expression of natural behaviors by free-living animals...
  17. ncbi request reprint Territorial aggression and hormones during the non-breeding season in a tropical bird
    Michaela Hau
    Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
    Horm Behav 45:40-9. 2004
    ..We conclude that male and female spotted antbirds can produce DHEA during the non-breeding season and DHEA may serve as a precursor of sex steroids for the regulation of year-round territorial behavior in both sexes...
  18. ncbi request reprint Estrogen contributes to seasonal plasticity of the adult avian song control system
    Kiran K Soma
    Department of Physiological Science, University of California, Los Angeles, California 90095 1527, USA
    J Neurobiol 58:413-22. 2004
    ..This study demonstrates that estrogen can affect adult neural plasticity on a gross anatomical scale and is the first examination of estrogen effects on the brain of a wild animal...
  19. pmc Recent advances in behavioral neuroendocrinology: insights from studies on birds
    James L Goodson
    Psychology Department, University of California, 5212 McGill Hall, San Diego, La Jolla, CA 92093 0109, USA
    Horm Behav 48:461-73. 2005
    ..We close by using birdsong as an example that links these areas together, thereby highlighting the exceptional opportunities that birds offer for integrative studies of behavioral neuroendocrinology and behavioral biology in general...
  20. pmc Cross-modal integration in a dart-poison frog
    Peter M Narins
    Department of Physiological Science, University of California, Los Angeles, CA 90095 1606, USA
    Proc Natl Acad Sci U S A 102:2425-9. 2005
    ....
  21. ncbi request reprint Dehydroepiandrosterone metabolism by 3beta-hydroxysteroid dehydrogenase/Delta5-Delta4 isomerase in adult zebra finch brain: sex difference and rapid effect of stress
    Kiran K Soma
    Department of Physiological Science, Laboratory of Neuroendocrinology of the Brain Research Institute, University of California, Los Angeles 90095 1527, USA
    Endocrinology 145:1668-77. 2004
    ..Songbirds are good animal models for studying the regulation and functions of DHEA and neurosteroids in the nervous system...
  22. pmc 3beta-HSD activates DHEA in the songbird brain
    Barney A Schlinger
    Department of Physiological Science, Laboratory of Neuroendocrinology of the Brain Research Institute, UCLA, Los Angeles, CA 90095, USA
    Neurochem Int 52:611-20. 2008
    ..Irrespective of its source, DHEA seems to be an important prohormone in songbirds, and 3beta-HSD is a key enzyme in the songbird brain...
  23. pmc Neuroprogesterone: key to estrogen positive feedback?
    Paul Micevych
    Department of Neurobiology, David Geffen School of Medicine, Laboratory of Neuroendocrinology, Brain Research Institute at UCLA, Los Angeles, CA 90095 1763, USA
    Brain Res Rev 57:470-80. 2008
    ..This neuroprogesterone also facilitated proceptive behavior. Blocking either progesterone synthesis or progesterone receptor in estrogen-primed ovx/adx prevented proceptive but not receptive behaviors...