D Barry Sinclair

Summary

Affiliation: University of Alberta
Country: Canada

Publications

  1. ncbi request reprint Absence epilepsy in childhood: electroencephalography (EEG) does not predict outcome
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta, 11402 University Avenue, Edmonton, Alberta, Canada
    J Child Neurol 22:799-802. 2007
  2. ncbi request reprint Valproic acid-induced pancreatitis in childhood epilepsy: case series and review
    D Barry Sinclair
    Division of Pediatric Neurology, 2C3 Walter MacKenzie Health Sciences Centre, University of Alberta, Edmonton, AB T6G 2R7, Canada
    J Child Neurol 19:498-502. 2004
  3. ncbi request reprint Discontinuation of antiepileptic drugs after pediatric epilepsy surgery
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 37:200-2. 2007
  4. doi request reprint Cortical tubers, cognition, and epilepsy in tuberous sclerosis
    Janani Kassiri
    Comprehensive Epilepsy Program, University of Alberta Hospital, Edmonton, Alberta, Canada
    Pediatr Neurol 44:328-32. 2011
  5. ncbi request reprint Depth electrodes in pediatric epilepsy surgery
    Janani Kassiri
    Comprehensive Epilepsy Program, University of Alberta Hospital, Edmonton, Alberta, Canada
    Can J Neurol Sci 40:48-55. 2013
  6. ncbi request reprint Tuberous sclerosis with open lipped schizencephaly
    Richard J Huntsman
    Division of Pediatric Neurology, University of Alberta, Alberta, Canada
    Pediatr Neurol 34:231-4. 2006
  7. ncbi request reprint Extratemporal resection for childhood epilepsy
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 30:177-85. 2004
  8. pmc Inflammasome induction in Rasmussen's encephalitis: cortical and associated white matter pathogenesis
    Vijay Ramaswamy
    Department of Psychiatry, University of Alberta, Edmonton, AB, Canada
    J Neuroinflammation 10:152. 2013
  9. ncbi request reprint Pediatric epilepsy surgery at the University of Alberta: 1988-2000
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 29:302-11. 2003
  10. doi request reprint Intelligence quotient is not affected by epilepsy surgery in childhood
    Anita N Datta
    Comprehensive Epilepsy Program, University of Alberta Hospital, Edmonton, Alberta, Canada
    Pediatr Neurol 44:117-21. 2011

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Absence epilepsy in childhood: electroencephalography (EEG) does not predict outcome
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta, 11402 University Avenue, Edmonton, Alberta, Canada
    J Child Neurol 22:799-802. 2007
    ..Associated comorbid features such as ADHD, learning disorders, and developmental delay are also seen in both groups. The outcome for both types is excellent, although the atypical variants may be initially more difficult to control...
  2. ncbi request reprint Valproic acid-induced pancreatitis in childhood epilepsy: case series and review
    D Barry Sinclair
    Division of Pediatric Neurology, 2C3 Walter MacKenzie Health Sciences Centre, University of Alberta, Edmonton, AB T6G 2R7, Canada
    J Child Neurol 19:498-502. 2004
    ..Children with known drug sensitivity might be at risk. Lipase levels at the time of an acute abdomen or a flulike illness in epileptic children taking valproic acid can reveal early stages of pancreatitis and are recommended...
  3. ncbi request reprint Discontinuation of antiepileptic drugs after pediatric epilepsy surgery
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 37:200-2. 2007
    ..Long-term antiepileptic drugs are not necessary in all cases, and for many children medication can be withdrawn after epilepsy surgery...
  4. doi request reprint Cortical tubers, cognition, and epilepsy in tuberous sclerosis
    Janani Kassiri
    Comprehensive Epilepsy Program, University of Alberta Hospital, Edmonton, Alberta, Canada
    Pediatr Neurol 44:328-32. 2011
    ..In addition, patients with intractable seizures and well-defined epileptic focus had excellent surgical outcome...
  5. ncbi request reprint Depth electrodes in pediatric epilepsy surgery
    Janani Kassiri
    Comprehensive Epilepsy Program, University of Alberta Hospital, Edmonton, Alberta, Canada
    Can J Neurol Sci 40:48-55. 2013
    ..In addition, we detail three individuals with distinct clinical scenarios in which depth electrodes were helpful and describe our technical approach to implantation and surgery...
  6. ncbi request reprint Tuberous sclerosis with open lipped schizencephaly
    Richard J Huntsman
    Division of Pediatric Neurology, University of Alberta, Alberta, Canada
    Pediatr Neurol 34:231-4. 2006
    ..This case supports the hypothesis that the cerebral lesions in tuberous sclerosis are secondary to a defect in neuronal maturation and migration...
  7. ncbi request reprint Extratemporal resection for childhood epilepsy
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 30:177-85. 2004
    ..A wide range of developmental pathology was observed including focal cortical dysplasia, brain tumors, and lesions with neurocutaneous syndromes. Many families reported improvement in behavior and psychosocial function after surgery...
  8. pmc Inflammasome induction in Rasmussen's encephalitis: cortical and associated white matter pathogenesis
    Vijay Ramaswamy
    Department of Psychiatry, University of Alberta, Edmonton, AB, Canada
    J Neuroinflammation 10:152. 2013
    ..Herein, the pathogenesis of RE was investigated focusing on inflammasome activation in the brain...
  9. ncbi request reprint Pediatric epilepsy surgery at the University of Alberta: 1988-2000
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 29:302-11. 2003
    ..Many children are seizure-free after the operation and remain so, although the results of temporal lobectomy are better than for extratemporal resections. There are few complications, and children often have an improved quality of life...
  10. doi request reprint Intelligence quotient is not affected by epilepsy surgery in childhood
    Anita N Datta
    Comprehensive Epilepsy Program, University of Alberta Hospital, Edmonton, Alberta, Canada
    Pediatr Neurol 44:117-21. 2011
    ..Overall, no significant change occurred in neuropsychologic parameters examined after surgery. Epilepsy surgery in childhood offers excellent surgical outcomes for seizure control, and does not adversely affect intelligence quotient...
  11. ncbi request reprint Posterior resection for childhood epilepsy
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta Hospital, Edmonton, Alberta, Canada
    Pediatr Neurol 32:257-63. 2005
    ..Visual abnormalities are an expected complication of surgery in the occipital lobe, but may improve over time...
  12. doi request reprint Psychosis with frontal lobe epilepsy responds to carbamazepine
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    J Child Neurol 23:431-4. 2008
    ..Treatment of the seizures with carbamazepine resulted in complete resolution of their psychiatric symptoms. The relationship between frontal lobe seizures and psychosis is explored...
  13. ncbi request reprint Epilepsia partialis continua: acute disseminated encephalomyelitis or Rasmussen's encephalitis?
    Vijay Ramaswamy
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 32:341-5. 2005
    ..The relevant literature is reviewed with an emphasis on possible etiologies, including both acute disseminated encephalomyelitis and Rasmussen's encephalitis...
  14. ncbi request reprint Frontal lobe epilepsy in childhood
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 30:169-76. 2004
    ..The condition is often misdiagnosed as a sleep disorder or psychiatric problem. Seizures are difficult to control but may respond to carbamazepine, valproic acid, or epilepsy surgery...
  15. ncbi request reprint Corticosteroids for the treatment of Landau-kleffner syndrome and continuous spike-wave discharge during sleep
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 32:300-6. 2005
    ..Side effects are few and reversible, and benefits appear long lasting. Corticosteroids should be considered as a treatment option in children with Landau-Kleffner syndrome and CSWS...
  16. ncbi request reprint Feasibility of epilepsy follow-up care through telemedicine: a pilot study on the patient's perspective
    Syed Nizamuddin Ahmed
    Department of Neurology, University of Alberta Hospital, Edmonton, Alberta, Canada
    Epilepsia 49:573-85. 2008
    ..Cost analysis and patient satisfaction with telemedicine in epilepsy care...
  17. ncbi request reprint Selective amygdalohippocampectomy: surgical outcome in children versus adults
    A Datta
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    Can J Neurol Sci 36:187-91. 2009
    ..The objective of the study was to review our experience with selective amygdalohippocampectomy (SAH) in children and adults with intractable temporal lobe epilepsy...
  18. ncbi request reprint Prednisone therapy in pediatric epilepsy
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 28:194-8. 2003
    ..It should be considered as an alternative treatment for older children with intractable generalized epilepsy who have failed conventional antiepileptic therapy...
  19. ncbi request reprint Pediatric temporal lobectomy for epilepsy
    D Barry Sinclair
    Comprehensive Epilepsy Program, University of Alberta Hospitals, Edmonton, Alta, Canada
    Pediatr Neurosurg 38:195-205. 2003
    ..Temporal lobectomy in adults is an accepted form of treatment for patients with intractable complex partial seizures. There have been few long-term studies of children undergoing temporal lobectomy for epilepsy...
  20. ncbi request reprint Benign epilepsy of childhood with rolandic spikes: typical and atypical variants
    Anita Datta
    Comprehensive Epilepsy Program, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 36:141-5. 2007
    ..Resolution of the epilepsy occurred in about the same length of time in both groups (but at different ages, consistent with different age of onset). Both groups had similar long-term outcome...
  21. ncbi request reprint Clinical significance of photic stimulation during routine EEGs of adult patients
    S Nizam Ahmed
    University of Alberta, Department of Medicine, Edmonton, Alberta, Canada
    Am J Electroneurodiagnostic Technol 46:356-62. 2006
    ..The abnormalities consisted of sharp waves in four patients and focal slowing in five patients. Only one patient had abnormalities on IPS that provided information additional to that seen on the baseline record...
  22. ncbi request reprint Atypical presentations of leigh syndrome: a case series and review
    Richard J Huntsman
    Department of Pediatric Neurology, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 32:334-40. 2005
    ..Many atypical variants are observed, of which clinicians should be aware. Evidence of brainstem or spinal cord involvement should also be sought in patients with Leigh syndrome...
  23. ncbi request reprint Neuroimaging features of acute disseminated encephalomyelitis in childhood
    Lawrence P Richer
    Division of Neurology, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Neurol 32:30-6. 2005
    ..However, a statistically significant association between complete resolution of magnetic resonance imaging signal abnormalities and a normal neurologic outcome was observed...
  24. pmc Dopamine modulates synaptic plasticity in dendrites of rat and human dentate granule cells
    Trevor J Hamilton
    Department of Pharmacology and Centre for Neuroscience, University of Alberta, Edmonton, AB, Canada T6G 2H7
    Proc Natl Acad Sci U S A 107:18185-90. 2010
    ..These results suggest that when dopamine is released in the dentate gyrus with concurrent high-frequency activity there is an increased probability that synapses will be strengthened and reward-associated spatial memories will be formed...
  25. ncbi request reprint Influenza B acute necrotizing encephalopathy: a case report and literature review
    Mona Sazgar
    Department of Medicine, University of Alberta Hospital, 2C3 Walter C MacKenzie Health Sciences Centre, 8440 112 Street, Edmonton, Alberta, Canada T6G 2B7
    Pediatr Neurol 28:396-9. 2003
    ..The literature on acute necrotizing encephalopathy is reviewed, and other causes of bilateral basal ganglia lesions are discussed...
  26. ncbi request reprint Intracranial calcification, retinopathy, and osteopenia: a new syndrome?
    Mona Sazgar
    Department of Medicine, Division of Neurology, University of Alberta Hospital, Edmonton, Canada
    Pediatr Neurol 26:324-8. 2002
    ..The younger brother also has osteopenia, mild splenomegaly, and pancytopenia. We review the literature with emphasis on the unique features of these patients...