Research Topics
| Donald D SinSummaryAffiliation: University of Alberta Country: Canada Publications
|
Detail Information
Publications
Outpatient antibiotic therapy and short term mortality in elderly patients with chronic obstructive pulmonary diseaseD D Sin
Sunnybrook and Women s College Health Science Centre, University of Toronto, Toronto, Canada
Can Respir J 7:466-71. 2000..To determine the association between outpatient use of oral antibiotics and 30-day all-cause mortality following hospitalization in a group of elderly chronic obstructive pulmonary disease (COPD) patients...
Inhaled corticosteroids and survival in chronic obstructive pulmonary disease: does the dose matter?D D Sin
Dept of Medicine, Pulmonary Division, University of Alberta, Edmonton, Canada
Eur Respir J 21:260-6. 2003..Low- was inferior to medium- or high-dose therapy in protecting against mortality in chronic obstructive pulmonary disease...
Why are patients with chronic obstructive pulmonary disease at increased risk of cardiovascular diseases? The potential role of systemic inflammation in chronic obstructive pulmonary diseaseDon D Sin
Department of Medicine, Pulmonary Division, University of Alberta, Edmonton, Alberta, Canada
Circulation 107:1514-9. 2003..Chronic obstructive pulmonary disease (COPD) increases the risk of cardiovascular disease 2- to 3-fold. The factors responsible for this association remain largely unknown...
Can universal access to health care eliminate health inequities between children of poor and nonpoor families?: A case study of childhood asthma in AlbertaDon D Sin
Department of Medicine, Pulmonary Division, University of Alberta, Edmonton, AB, Canada
Chest 124:51-6. 2003..We sought to determine whether in a health-care system that provides free access to outpatient and hospital services, the disparities in the rates of emergency visits for asthma would be less apparent across the income gradient...
Impaired lung function and serum leptin in men and women with normal body weight: a population based studyD D Sin
Department of Medicine, Pulmonary Division, University of Alberta, Edmonton, Alberta, Canada
Thorax 58:695-8. 2003..Whether circulating factors are responsible for this association is unknown. A study was undertaken to determine whether leptin, a hormone that can promote atherothrombosis, is raised in individuals with impaired lung function...
Inhaled corticosteroids in the long-term management of patients with chronic obstructive pulmonary diseaseDon D Sin
The Department of Medicine, Pulmonary Division, University of Alberta, Edmonton, Alberta, Canada
Drugs Aging 20:867-80. 2003....
Contemporary management of chronic obstructive pulmonary disease: scientific reviewDon D Sin
Division of Pulmonary Medicine, University of Alberta, Edmonton, Canada
JAMA 290:2301-12. 2003..The care of patients with chronic obstructive pulmonary disease (COPD) has changed radically over the past 2 decades, and novel therapies can not only improve the health status of patients with COPD but also modify its natural course...
The relationship between birth weight and childhood asthma: a population-based cohort studyDon D Sin
Pulmonary Division, The Department of Medicine, University of Alberta, Edmonton, Canada
Arch Pediatr Adolesc Med 158:60-4. 2004..Because obesity promotes inflammation and imposes mechanical constraints to the airways, a high birth weight may be a risk factor for asthma in childhood. However, to our knowledge, few studies have examined this potential relationship...
Cost-effectiveness of inhaled corticosteroids for chronic obstructive pulmonary disease according to disease severityDonald D Sin
Institute of Health Economics, Department of Medicine, University of Alberta, Edmonton, Canada
Am J Med 116:325-31. 2004..Inhaled corticosteroids reduce exacerbations in patients with chronic obstructive pulmonary disease (COPD), but their cost-effectiveness is not known...
The risk of osteoporosis in Caucasian men and women with obstructive airways diseaseDon D Sin
Division of Pulmonary Medicine, University of Alberta, Edmonton, Alberta, Canada
Am J Med 114:10-4. 2003..Because patients with obstructive airways disease may be susceptible to osteoporosis, we sought to determine the association between airflow obstruction and osteoporosis...
Can continuous positive airway pressure therapy improve the general health status of patients with obstructive sleep apnea?: a clinical effectiveness studyDon D Sin
Departments of Pulmonary Medicine, University of Alberta, Edmonton, AB, Canada
Chest 122:1679-85. 2002..To determine the short-term and long-term impacts of continuous positive airway pressure (CPAP) therapy on health-related quality of life (HRQL) in patients with obstructive sleep apnea (OSA)...
Underuse of inhaled steroid therapy in elderly patients with asthmaD D Sin
Department of Medicine, Sunnybrook and Women s College Health Science Center, University of Toronto, Toronto, Ontario, Canada
Chest 119:720-5. 2001....
Do area-based markers of poverty accurately measure personal poverty?D D Sin
Division of Pulmonary Medicine, Department of Medicine, University of Alberta, Edmonton, AB
Can J Public Health 92:184-7. 2001..26 to 1.27) and 2.01 (99% CI, 2.01 to 2.02), respectively. The use of postal codes as the only marker to identify people with low SES may result in substantial misclassification of personal poverty, particularly in non-metropolitan areas...
Inhaled corticosteroids and the risk of mortality and readmission in elderly patients with chronic obstructive pulmonary diseaseD D Sin
The Institute for Clinical Evaluative Sciences and The Department of Medicine, Sunnybrook and Women s College Health Science Center, University of Toronto, Toronto, Ontario, Canada
Am J Respir Crit Care Med 164:580-4. 2001....
Long-term compliance rates to continuous positive airway pressure in obstructive sleep apnea: a population-based studyDon D Sin
Department of Pulmonary Medicine, University of Alberta, Edmonton, AB, Canada
Chest 121:430-5. 2002..To determine long-term compliance rates to continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnea enrolled in a comprehensive CPAP program in the community...
The impact of chronic obstructive pulmonary disease on work loss in the United StatesDon D Sin
Department of Medicine Pulmonary Division, Institute of Health Economics, 2E4 29 Walter C Mackenzie Centre, University of Alberta, Edmonton, Alberta, T6G 2B7 Canada
Am J Respir Crit Care Med 165:704-7. 2002..These data suggest that COPD has a considerable adverse impact on work force participation. Based on these data, we estimate that, in 1994, COPD was responsible for work loss of approximately $9.9 billion in the U.S...
Asthma and COPD among aboriginals in Alberta, CanadaDon D Sin
Department of Medicine, Pulmonary Division, University of Alberta, Edmonton, Alberta, Canada
Chest 121:1841-6. 2002..Although there is a greater prevalence of smoking, poor housing, and overcrowding in aboriginal than nonaboriginal communities, the rates of office and emergency visits for asthma and COPD among aboriginals are not well known...
Obesity is a risk factor for dyspnea but not for airflow obstructionDon D Sin
Department of Medicine, University of Alberta, Edmonton, Canada T6G 2B7
Arch Intern Med 162:1477-81. 2002..However, since obesity can cause dyspnea through mechanisms other than airflow obstruction, diagnostic misclassification of asthma could partially account for this association...
Low-dose inhaled corticosteroid therapy and risk of emergency department visits for asthmaDon D Sin
Division of Pulmonary Medicine, University of Alberta, Edmonton, Alberta, Canada T6G 2B7
Arch Intern Med 162:1591-5. 2002..While the use of inhaled corticosteroids has been demonstrated to improve asthma symptoms and lung function, it is not clear whether their use after discharge from the ED reduces asthma relapse rates...
Sex differences in severe pulmonary emphysemaFernando J Martinez
University of Michigan, Division of Pulmonary and Critical Care Medicine, Ann Arbor, Michigan 48109 0360, USA
Am J Respir Crit Care Med 176:243-52. 2007..Limited data on sex differences in advanced COPD are available...
