Research Topics
| Scot H SimpsonSummaryAffiliation: University of Alberta Country: Canada Publications
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Publications
Effect of aspirin dose on mortality and cardiovascular events in people with diabetes: a meta-analysisScot H Simpson
Faculty of Pharmacy and Pharmaceutical Sciences, 3126 Dentistry Pharmacy Centre, University of Alberta, Edmonton, AB, Canada, T6G 2N8
J Gen Intern Med 26:1336-44. 2011..This meta-analysis explored the relationship between aspirin dose and prevention of cardiovascular events...
Effect of adding pharmacists to primary care teams on blood pressure control in patients with type 2 diabetes: a randomized controlled trialScot H Simpson
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Alberta, Canada
Diabetes Care 34:20-6. 2011..To evaluate the effect of adding pharmacists to primary care teams on the management of hypertension and other cardiovascular risk factors in patients with type 2 diabetes...
A meta-analysis of the association between adherence to drug therapy and mortalityScot H Simpson
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada T6G 2N8
BMJ 333:15. 2006..To evaluate the relation between adherence to drug therapy, including placebo, and mortality...
The natural history of LDL control in type 2 diabetes: a prospective study of adherence to lipid guidelinesDiana Rucker
University of Alberta, 2E3.07 Walter Mackenzie Health Sciences Centre, University of Alberta Hospital, 8440-112th St, Edmonton, Alberta, Canada
Diabetes Care 29:2506-8. 2006
Recurrent community-acquired pneumonia in patients starting acid-suppressing drugsDean T Eurich
Department of Public Health Sciences, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
Am J Med 123:47-53. 2010..To test this hypothesis, we examined a prospective population-based cohort predisposed to pneumonia: elderly patients (> or =65 years) who had survived hospitalization for pneumonia...
Greater effect of enhanced pharmacist care on cholesterol management in patients with diabetes mellitus: a planned subgroup analysis of the Study of Cardiovascular Risk Intervention by Pharmacists (SCRIP)Scot H Simpson
Institute of Health Economics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada
Pharmacotherapy 24:389-94. 2004..Results of this substudy suggest that pharmacists should target this patient group for interventions in cholesterol risk management...
Dose-response relation between sulfonylurea drugs and mortality in type 2 diabetes mellitus: a population-based cohort studyScot H Simpson
Institute of Health Economics, Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alta
CMAJ 174:169-74. 2006..The same relation was not observed with metformin. This implies that the manner in which blood glucose concentration is lowered may be as important as achieving recommended glucose targets...
The darkening cloud of diabetes: do trends in cardiovascular risk management provide a silver lining?Dean T Eurich
School of Public Health, University of Alberta, Edmonton, Alberta, Canada
Diabetes Care 31:2136-42. 2008..We aimed to evaluate the changes in cardiovascular-related health care utilization (drug therapies, hospitalizations) and mortality for the diabetic population during a 9-year period in Saskatchewan, Canada...
Do guidelines guide pneumonia practice? A systematic review of interventions and barriers to best practice in the management of community-acquired pneumoniaScot H Simpson
Institute of Health Economics, 10405 Jasper Ave, Edmonton, Alberta T5J 3N4, Canada
Respir Care Clin N Am 11:1-13. 2005..Paper does not change practice, and the creation and mailing out of a practice guideline for the treatment of CAP is only the first necessary step in translating good evidence into everyday clinical practice...
Secondary failure rates associated with metformin and sulfonylurea therapy for type 2 diabetes mellitusDean T Eurich
Institute of Health Economics, Edmonton, Alberta, Canada
Pharmacotherapy 25:810-6. 2005..43, 95% CI 1.17-1.75). CONCLUSION: Compared with sulfonylurea therapy, metformin therapy appears to be associated with a delay in the onset of secondary failure...
Adding pharmacists to primary care teams increases guideline-concordant antiplatelet use in patients with type 2 diabetes: results from a randomized trialFizza Gilani
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Ann Pharmacother 47:43-8. 2013..Antiplatelet therapy is recommended as part of a strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes. However, compliance with these guideline-recommended therapies appears to be less than ideal...
Hypertension treatment and control rates: chart review in an academic family medicine clinicSara J Houlihan
University of Alberta, Edmonton, AB T6G 2N8
Can Fam Physician 55:735-41. 2009..To characterize hypertension management in an academic family medicine clinic...
Evaluating the views of paramedics, cardiologists, emergency department physicians and nurses on advanced prehospital management of acute ST elevation myocardial infarctionNaheed A Rajabali
Walter C Mackenzie Health Sciences Centre, University of Alberta Hospital, Edmonton, Alberta T6G 2B7, Canada
Can J Cardiol 25:e323-8. 2009..Understanding perceived barriers to and facilitators of PHM implementation may support the expansion of programs, with associated patient benefit...
Development and validation of a survey to assess barriers to drug use in patients with chronic heart failureScot H Simpson
Institute of Health Economics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada
Pharmacotherapy 22:1163-72. 2002..Conclusion. The BMU survey demonstrated reasonable reliability and validity characteristics in this first clinical experience. Despite high adherence, patients still reported barriers that may hinder optimal drug use...
Short-term risk for stroke is doubled in persons with newly treated type 2 diabetes compared with persons without diabetes: a population-based cohort studyThomas Jeerakathil
Division of Neurology, University of Alberta, Edmonton, Alberta, Canada, T6G 2B7
Stroke 38:1739-43. 2007..We determined the incidence of stroke in people newly treated for type 2 diabetes...
Pharmacist care of patients with heart failure: a systematic review of randomized trialsSheri L Koshman
Division of Cardiology, Faculty of Medicine and Dentistry, EPICORE Centre COMPRIS, University of Alberta, 220 College Plaza, 8215 112 St NW, Edmonton, Alberta, AB T6G 2C8 Canada
Arch Intern Med 168:687-94. 2008..To clarify the role of pharmacists in the care of patients with HF, we performed a systematic review evaluating the effect of pharmacist care on patient outcomes in HF...
Treatment and blood pressure control in 47,964 people with diabetes and hypertension: a systematic review of observational studiesDonna L McLean
Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton
Can J Cardiol 22:855-60. 2006..There is an urgent need for multidisciplinary, community-based approaches to manage these high-risk patients...
Decreased mortality associated with the use of metformin compared with sulfonylurea monotherapy in type 2 diabetesJeffrey A Johnson
Department of Public Health Sciences, University of Alberta, Edmonton, Canada
Diabetes Care 25:2244-8. 2002..The aim of this study was to examine the relationship between use of metformin and sulfonylurea and mortality in new users of these agents...
Angiotensin receptor blockers and risk of myocardial infarction: systematic reviewMichael A McDonald
Division of Cardiology, University of Alberta, 2C2 WMC, University of Alberta Hospital, 8440-112 Street, Edmonton, AB, Canada T6G 2B7
BMJ 331:873. 2005..Until further information specifically dealing with this issue is available from large prospective trials, our findings may alleviate recent concerns over the safety of this class of medications...
Physician-perceived barriers to adopting a critical pathway for unity-acquired pneumoniaSumit R Majumdar
Department of Medicine, University of Alberta, Edmonton
Jt Comm J Qual Saf 30:387-95. 2004..For example, local audit and feedback of outcomes data to persuade physicians of the benefits of CAP pathways will need to be instituted...
Development of educational materials for congestive-heart-failure patientsMiriam Fradette
Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada
Am J Health Syst Pharm 61:386-9. 2004
A randomized trial of the effect of community pharmacist intervention on cholesterol risk management: the Study of Cardiovascular Risk Intervention by Pharmacists (SCRIP)Ross T Tsuyuki
Epidemiology Coordinating and Research EPICORE Centre, Division of Cardiology, University of Alberta, 213 Heritage Medical Research Centre, Edmonton, Alberta, Canada T6G 2S2
Arch Intern Med 162:1149-55. 2002..This study aimed to determine the effect of a program of community pharmacist intervention on the process of cholesterol risk management in patients at high risk for cardiovascular events...
Enhancing hypertension awareness and management in the elderly: lessons learned from the Airdrie Community Hypertension Awareness and Management Program (A-CHAMP)Charlotte Jones
University of Calgary, Calgary, Canada
Can J Cardiol 24:561-7. 2008..High blood pressure (BP) is an established and modifiable cardiovascular risk factor; however, awareness and management of this primarily asymptomatic disease remains suboptimal...
The cost of major comorbidity in people with diabetes mellitusScot H Simpson
Institute of Health Economics, Edmonton, Alta
CMAJ 168:1661-7. 2003..INTERPRETATION: In 1996, 36.4% of health care expenditures for people with diabetes was attributable to major comorbidity. Actions to prevent or control such comorbidity will yield significant cost savings...
