Affiliation: University of Toronto
- Analysis of the role of IL-21 in development of murine B cell progenitors in the bone marrowNathalie Simard
Ontario Cancer Institute, Princess Margaret Hospital, University Health Network, Toronto, Ontario M5G 2M9, Canada
J Immunol 186:5244-53. 2011..We also report in this paper that IL-21 is expressed by BM CD4(+) T cells. These results provide evidence that IL-21R is functional in B cell progenitors and indicate that IL-21 regulates B cell development...
- IL-21: an executor of B cell fateDanijela Konforte
Division of Stem Cell and Developmental Biology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, Toronto, Canada
J Immunol 182:1781-7. 2009..This review highlights the role of IL-21 in B cell development, function, and disease and provides some perspectives on the future studies in this area...
- Interleukin-21 regulates expression of key Epstein-Barr virus oncoproteins, EBNA2 and LMP1, in infected human B cellsDanijela Konforte
Division of Stem Cell and Developmental Biology, Princess Margaret Hospital, Ontario Cancer Institute, University Health Network, Toronto, Canada M5G 2M9
Virology 374:100-13. 2008..Our study also shows that IL-21 induced transcription of ebna1 from the viral Q promoter (Qp)...