Kevin Shoemaker

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. pmc Central versus peripheral cardiovascular risk in metabolic syndrome
    H Edgell
    Department of Kinesiology, University of Western Ontario London, ON, Canada
    Front Physiol 3:38. 2012
  2. doi request reprint Altered cortical activation patterns associated with baroreflex unloading following 24 h of physical deconditioning
    J K Shoemaker
    Neurovascular Research Laboratory, Faculty of Health Sciences, The University of Western Ontario, London, Ontario, Canada
    Exp Physiol 97:1249-62. 2012
  3. doi request reprint Differential regulation of sympathetic burst frequency and amplitude following acute hypoxia in humans
    Craig D Steinback
    Department of Physiology and Pharmacology, University of Calgary, Alberta, Canada
    Am J Physiol Regul Integr Comp Physiol 303:R633-8. 2012
  4. doi request reprint Cortical circuitry associated with reflex cardiovascular control in humans: does the cortical autonomic network "speak" or "listen" during cardiovascular arousal
    J Kevin Shoemaker
    School of Kinesiology, Department of Physiology and Pharmacology, The University of Western Ontario, London, Ontario, Canada N6A 3K7
    Anat Rec (Hoboken) 295:1375-84. 2012
  5. doi request reprint Forebrain organization representing baroreceptor gating of somatosensory afferents within the cortical autonomic network
    Ruma Goswami
    School of Kinesiology, Western University, London, Ontario, Canada
    J Neurophysiol 108:453-66. 2012
  6. doi request reprint Baroreflex mechanisms regulating the occurrence of neural spikes in human muscle sympathetic nerve activity
    Aryan Salmanpour
    Department of Electrical and Computer Engineering, University of Western Ontario, London, Ontario, Canada
    J Neurophysiol 107:3409-16. 2012
  7. pmc Lifestyle modification and metformin as long-term treatment options for obese adolescents: study protocol
    A Justine Wilson
    Department of Health Sciences, School of Kinesiology, The University of Western Ontario, Ontario, Canada
    BMC Public Health 9:434. 2009
  8. pmc Stuttered swallowing: electric stimulation of the right insula interferes with water swallowing. A case report
    Peter Soros
    School of Communication Sciences and Disorders, University of Western Ontario, London, Ontario, Canada
    BMC Neurol 11:20. 2011
  9. ncbi request reprint Peripheral chemoreceptor contributions to sympathetic and cardiovascular responses during hypercapnia
    J K Shoemaker
    Neurovascular Research Laboratory, Room 3110, Thames Hall, School of Kinesiology, The University of Western Ontario, London, ON N6A 3K7, Canada
    Can J Physiol Pharmacol 80:1136-44. 2002
  10. ncbi request reprint Gender affects sympathetic and hemodynamic response to postural stress
    J K Shoemaker
    Neurovascular Research Laboratory, School of Kinesiology, University of Western Ontario, London, Ontario, Canada, N6A 3K7
    Am J Physiol Heart Circ Physiol 281:H2028-35. 2001

Collaborators

Detail Information

Publications38

  1. pmc Central versus peripheral cardiovascular risk in metabolic syndrome
    H Edgell
    Department of Kinesiology, University of Western Ontario London, ON, Canada
    Front Physiol 3:38. 2012
    ..These data also indicate that variance in between-group responses due to pharmacological treatments are important factors to consider in studying cardiovascular changes in these individuals...
  2. doi request reprint Altered cortical activation patterns associated with baroreflex unloading following 24 h of physical deconditioning
    J K Shoemaker
    Neurovascular Research Laboratory, Faculty of Health Sciences, The University of Western Ontario, London, Ontario, Canada
    Exp Physiol 97:1249-62. 2012
    ..The results suggest that physical activity patterns exert a rapid and notable impact on the cortical circuitry associated with cardiovascular control...
  3. doi request reprint Differential regulation of sympathetic burst frequency and amplitude following acute hypoxia in humans
    Craig D Steinback
    Department of Physiology and Pharmacology, University of Calgary, Alberta, Canada
    Am J Physiol Regul Integr Comp Physiol 303:R633-8. 2012
    ..These data indicate the differential regulation of pattern and magnitude of sympathetic outflow in humans with sympathetic persistence following HX being specific to burst frequency and not amplitude...
  4. doi request reprint Cortical circuitry associated with reflex cardiovascular control in humans: does the cortical autonomic network "speak" or "listen" during cardiovascular arousal
    J Kevin Shoemaker
    School of Kinesiology, Department of Physiology and Pharmacology, The University of Western Ontario, London, Ontario, Canada N6A 3K7
    Anat Rec (Hoboken) 295:1375-84. 2012
    ..Thus, the cortical pathways subserving reflex cardiovascular control integrate viscerosensory inputs with outgoing traffic that modulates the autonomic nervous system...
  5. doi request reprint Forebrain organization representing baroreceptor gating of somatosensory afferents within the cortical autonomic network
    Ruma Goswami
    School of Kinesiology, Western University, London, Ontario, Canada
    J Neurophysiol 108:453-66. 2012
    ..These findings reveal that the level of baroreceptor input influences the forebrain organization of somatosensory afferents...
  6. doi request reprint Baroreflex mechanisms regulating the occurrence of neural spikes in human muscle sympathetic nerve activity
    Aryan Salmanpour
    Department of Electrical and Computer Engineering, University of Western Ontario, London, Ontario, Canada
    J Neurophysiol 107:3409-16. 2012
    ....
  7. pmc Lifestyle modification and metformin as long-term treatment options for obese adolescents: study protocol
    A Justine Wilson
    Department of Health Sciences, School of Kinesiology, The University of Western Ontario, Ontario, Canada
    BMC Public Health 9:434. 2009
    ..This paper will provide the background rationale and methods of the REACH childhood obesity treatment program...
  8. pmc Stuttered swallowing: electric stimulation of the right insula interferes with water swallowing. A case report
    Peter Soros
    School of Communication Sciences and Disorders, University of Western Ontario, London, Ontario, Canada
    BMC Neurol 11:20. 2011
    ..However, the exact location of insular activation during swallowing and its functional significance remain unclear...
  9. ncbi request reprint Peripheral chemoreceptor contributions to sympathetic and cardiovascular responses during hypercapnia
    J K Shoemaker
    Neurovascular Research Laboratory, Room 3110, Thames Hall, School of Kinesiology, The University of Western Ontario, London, ON N6A 3K7, Canada
    Can J Physiol Pharmacol 80:1136-44. 2002
    ..The combined data indicate that peripheral chemoreceptors exert important influence over cardiovascular reflex responses to hypercapnia...
  10. ncbi request reprint Gender affects sympathetic and hemodynamic response to postural stress
    J K Shoemaker
    Neurovascular Research Laboratory, School of Kinesiology, University of Western Ontario, London, Ontario, Canada, N6A 3K7
    Am J Physiol Heart Circ Physiol 281:H2028-35. 2001
    ..The different MSNA response to postural stress between genders may contribute importantly to decrements in blood pressure control during HUT in females...
  11. ncbi request reprint Gender affects sympathetic neurovascular control during postural stress
    J K Shoemaker
    School of Kinesiology, University of Western Ontario, London, Ontario, Canada
    J Gravit Physiol 9:P83-4. 2002
    ..The purpose of this report is to examine the hypothesis that gender differences in blood pressure control during HUT are related to important variations in MSNA discharge patterns...
  12. ncbi request reprint PET(CO(2)) inversely affects MSNA response to orthostatic stress
    J K Shoemaker
    School of Kinesiology, University of Western Ontario, London, Ontario N6A 3K7
    Am J Physiol Heart Circ Physiol 281:H1040-6. 2001
    ..Therefore, the MSNA response to HUT varied inversely with levels of PET(CO(2)). The combined data suggest that augmented cardiac output with hypercapnia sustained blood pressure during HUT leading to a diminished sympathetic response...
  13. ncbi request reprint WISE 2005: stroke volume changes contribute to the pressor response during ischemic handgrip exercise in women
    J K Shoemaker
    School of Kinesiology and Department of Physiology and Pharmacology, The University of Western Ontario, London, Ontario, Canada
    J Appl Physiol (1985) 103:228-33. 2007
    ..The data indicate that the majority of the blood pressure response to isometric handgrip exercise in women was due to mobilization of central blood volume and elevated stroke volume and Q rather than elevations in TVR or LVR resistance...
  14. ncbi request reprint WISE 2005: flow and nitroglycerin mediated dilation following 56 days of head down tilt bed rest with and without an exercise countermeasure
    K S Dyson
    Cardiorespiratory and Vascular Dynamics Lab, Univ Waterloo, Waterloo, Ontario, Canada
    J Gravit Physiol 14:P55-6. 2007
    ..NMD appears to be elevated in the popliteal and femoral in the absence of exercise, but unchanged in the brachial artery or at any site for EX...
  15. ncbi request reprint WISE 2005: vascular responses to 60-day bed rest in women
    R L Hughson
    Cardiorespiratory and Vascular Dynamics Lab, Univ Waterloo, Waterloo, Ontario, Canada
    J Gravit Physiol 14:P53-4. 2007
    ..We conclude that consistent changes in cardiovascular function in the No-EX were detected by different methods that point to mechanisms contributing to orthostatic intolerance after HDBR...
  16. ncbi request reprint Test-retest repeatability of muscle sympathetic nerve activity: influence of data analysis and head-up tilt
    D S Kimmerly
    Neurovascular Research Laboratory, School of Kinesiology, University of Western Ontario, Room 3110 Thames Hall, London, Ontario, Canada N6A 3K7
    Auton Neurosci 114:61-71. 2004
    ..However, care must be taken when using percent changes in MSNA that incorporate absolute amplitudes...
  17. ncbi request reprint Critical analysis of cerebrovascular autoregulation during repeated head-up tilt
    R L Hughson
    Cardiorespiratory and Vascular Dynamics Laboratory, Faculty of Applied Health Sciences, University of Waterloo, Waterloo, Ontario, Canada
    Stroke 32:2403-8. 2001
    ..We investigated these relations during spontaneous fluctuations (control) and repeated head-up tilt...
  18. ncbi request reprint Heterogeneity of responses to orthostatic stress in homozygous twins
    D D O'Leary
    Department of Community Health Sciences, Brock University, St Catharines, Ontario, Canada
    J Appl Physiol (1985) 102:249-54. 2007
    ..Therefore, although orthostatic tolerance times were very similar between identical twins, the mechanism involved in sustaining cardiovascular function during increasing stress was different...
  19. ncbi request reprint Forebrain neural patterns associated with sex differences in autonomic and cardiovascular function during baroreceptor unloading
    D S Kimmerly
    Neurovascular Research Laboratory, Faculty of Health Sciences and School of Kinesiology, The University of Western Ontario, London, Ontario, Canada
    Am J Physiol Regul Integr Comp Physiol 292:R715-22. 2007
    ..women. The greater changes in forebrain activity in men vs. women may have contributed to the elevated HR and sympathetic responses observed in men during 35 mmHg LBNP...
  20. ncbi request reprint Forebrain regions associated with postexercise differences in autonomic and cardiovascular function during baroreceptor unloading
    D S Kimmerly
    Neurovascular Research Laboratory, Faculty of Health Sciences and School of Kinesiology, The University of Western Ontario, London, Ontario, Canada
    Am J Physiol Heart Circ Physiol 293:H299-306. 2007
    ..NO-EX). Our findings suggest that discrete forebrain regions may be involved with the generation of baroreflex-mediated sympathetic and cardiovascular responses elicited by moderate LBNP...
  21. ncbi request reprint Splanchnic and peripheral vascular resistance during lower body negative pressure (LBNP) and tilt
    R L Hughson
    Cardiorespiratory and Vascular Dynamics Lab, Univ Waterloo, Waterloo, Ontario, Canada
    J Gravit Physiol 11:P95-6. 2004
    ....
  22. ncbi request reprint Dependence of muscle VO2 on blood flow dynamics at onset of forearm exercise
    R L Hughson
    Department of Kinesiology, University of Waterloo, Ontario, Canada
    J Appl Physiol (1985) 81:1619-26. 1996
    ..These data support the hypothesis that changes in blood flow at the onset of exercise have a direct effect on oxidative metabolism through alterations in O2 transport...
  23. ncbi request reprint Cardiorespiratory kinetics and femoral artery blood velocity during dynamic knee extension exercise
    J K Shoemaker
    Department of Kinesiology, University of Waterloo, Ontario, Canada
    J Appl Physiol (1985) 77:2625-32. 1994
    ....
  24. ncbi request reprint Vascular health in space
    R L Hughson
    Cardiorespiratory and Vascular Dynamics Lab, Univ Waterloo, Waterloo, Ontario, Canada
    J Gravit Physiol 11:P71-4. 2004
    ....
  25. ncbi request reprint Circulating norepinephrine and cerebrovascular control in conscious humans
    D S Kimmerly
    Neurovascular Research Lab, University of Western Ontario, London, Ontario, Canada
    Clin Physiol Funct Imaging 23:314-9. 2003
    ..Therefore, we tested the hypothesis that alpha-adrenergic activation with and without elevated circulating norepinephrine (NE) directly affects cerebrovascular tone in healthy individuals...
  26. ncbi request reprint Differential effect of head-up tilt on cardiovagal and sympathetic baroreflex sensitivity in humans
    D D O'Leary
    Neurovascular Research Laboratory, School of Kinesiology, The University of Western Ontario, London, Ontario, Canada N6A 3K7
    Exp Physiol 88:769-74. 2003
    ..01). Thus, HUT produced differential effects on cardiac versus sympathetic BRS. The data suggest that dynamic baroreflex-mediated cardiovascular control is dominated by sympathetic control during baroreceptor unloading...
  27. ncbi request reprint Hypovolemia and MSNA discharge patterns: assessing and interpreting sympathetic responses
    D S Kimmerly
    Neurovascular Research Laboratory, School of Kinesiology, University of Western Ontario, London, N6A 3K7 Ontario, Canada
    Am J Physiol Heart Circ Physiol 284:H1198-204. 2003
    ..Furthermore, the differential effect of hypovolemia on the responses of burst frequency and amplitude during graded LBNP suggests that burst frequency data alone may not adequately represent reflex control of sympathetic outflow...
  28. ncbi request reprint Role of vascular bed compliance in vasomotor control in human skeletal muscle
    M Zamir
    Departments of Applied Mathematics and of Medical Biophysics, The University of Western Ontario, London, Ontario N6A 3K7, Canada
    Exp Physiol 92:841-8. 2007
    ..05). It was concluded that vascular bed compliance is an independent variable which should be considered along with vascular bed resistance in the mechanics of vasomotor regulation in skeletal muscle...
  29. doi request reprint Adrenergic and myogenic regulation of viscoelasticity in the vascular bed of the human forearm
    M F Frances
    School of Kinesiology, Oulu, Finland
    Exp Physiol 96:1129-37. 2011
    ..Additionally, forearm vascular compliance is sensitive to baseline levels of ╬▒AR activation when transmural pressure is low...
  30. ncbi request reprint Altered hormonal regulation and blood flow distribution with cardiovascular deconditioning after short-duration head down bed rest
    D Fischer
    Faculty of Applied Health Sciences, University of Waterloo, Waterloo, ON, Canada
    J Appl Physiol 103:2018-25. 2007
    ..Impaired ability to distribute blood away from the splanchnic region was associated with reduced stroke volume, elevated heart rate, and the inability to protect mean arterial pressure...
  31. doi request reprint Myogenic activity in autoregulation during low frequency oscillations
    M Zamir
    Neurovascular Research Laboratory, School of Kinesiology, The University of Western Ontario, London, Ontario, Canada
    Auton Neurosci 159:104-10. 2011
    ..These findings provide a possible resolution of a longstanding conceptual argument against attributing a significant role for the myogenic response in blood flow autoregulation...
  32. doi request reprint Detection and classification of raw action potential patterns in human Muscle Sympathetic Nerve Activity
    Aryan Salmanpour
    Department of Electrical and Computer Engineering, and the Neurovascular Research Laboratory, the School of Kinesiology, The University of Western Ontario, ON, Canada
    Conf Proc IEEE Eng Med Biol Soc 2008:2928-31. 2008
    ..The action potential detector and classification algorithm are evaluated using real MSNA recorded from three healthy subjects...
  33. ncbi request reprint Innovation to reduce cardiovascular complications of diabetes at the intersection of discovery, prevention and knowledge exchange
    Earl Noble
    School of Kinesiology, Faculty of Health Sciences, University of Western Ontario, London, Ontario, Canada
    Can J Diabetes 37:282-93. 2013
    ....
  34. pmc Efficacy of a family practice-based lifestyle intervention program to increase physical activity and reduce clinical and physiological markers of vascular health in patients with high normal blood pressure and/or high normal blood glucose (SNAC): study pr
    Robert J Petrella
    Dept of Family Medicine, Schulich School of Medicine, University of Western Ontario, Canada
    Trials 12:45. 2011
    ..In particular, family practice represents an ideal setting for the provision and long-term maintenance of lifestyle interventions for patients at risk (ie high-normal blood pressure or impaired glucose tolerance)...
  35. pmc Diabetes and Technology for Increased Activity (DaTA) study: results of a remote monitoring intervention for prevention of metabolic syndrome
    Melanie Stuckey
    School of Kinesiology, University of Western Ontario, London, Ontario, Canada
    J Diabetes Sci Technol 5:928-35. 2011
    ....
  36. pmc Sympathetic neural activation: an ordered affair
    Craig D Steinback
    Neurovascular Research Laboratory, School of Kinesiology, University of Western Ontario, London, ON, Canada
    J Physiol 588:4825-36. 2010
    ....
  37. doi request reprint Relationship between size and latency of action potentials in human muscle sympathetic nerve activity
    Aryan Salmanpour
    Department of Electrical and Computer Engineering, University of Western Ontario, London, Ontario, Canada
    J Neurophysiol 105:2830-42. 2011
    ..e., larger amplitude bursts). This fundamental pattern was evident at rest and was not altered by the level of baroreceptor unloading applied in this study...
  38. ncbi request reprint Blood flow and muscle oxygen uptake at the onset and end of moderate and heavy dynamic forearm exercise
    M C van Beekvelt
    Department of Kinesiology, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada
    Am J Physiol Regul Integr Comp Physiol 280:R1741-7. 2001
    ..During moderate exercise, O(2) supply met requirements, but with heavy forearm exercise, inadequate O(2) supply during exercise caused accumulation of a large O(2) deficit that was repaid during recovery...