Jerry Shapiro

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. ncbi request reprint Safety of topical minoxidil solution: a one-year, prospective, observational study
    Jerry Shapiro
    Division of Dermatology, Department of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada
    J Cutan Med Surg 7:322-9. 2003
  2. ncbi request reprint Alopecia areata: pathogenesis and potential for therapy
    Wei Lu
    Department of Dermatology and Skin Science, University of British Columbia, 835 West 10th Avenue, Vancouver, BC, V5Z 4E8, Canada
    Expert Rev Mol Med 8:1-19. 2006
  3. pmc Practical management of hair loss
    J Shapiro
    Division of Dermatology, University of British Columbia UBC, Vancouver
    Can Fam Physician 46:1469-77. 2000
  4. doi request reprint Lichen planopilaris and pseudopelade of Brocq involve distinct disease associated gene expression patterns by microarray
    Mei Yu
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, Canada
    J Dermatol Sci 57:27-36. 2010
  5. doi request reprint Pattern hair loss in men: diagnosis and medical treatment
    Nusrat Banka
    Department of Dermatology and Skin Science, University of British Columbia, 835 West 10th Avenue, Vancouver, BC, Canada
    Dermatol Clin 31:129-40. 2013
  6. doi request reprint Somatostatin expression in human hair follicles and its potential role in immune privilege
    Trisia Breitkopf
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    J Invest Dermatol 133:1722-30. 2013
  7. doi request reprint Alopecia areata update: part II. Treatment
    Abdullah Alkhalifah
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    J Am Acad Dermatol 62:191-202, quiz 203-4. 2010
  8. doi request reprint Hair follicle mesenchyme-associated PD-L1 regulates T-cell activation induced apoptosis: a potential mechanism of immune privilege
    Xiaojie Wang
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    J Invest Dermatol 134:736-45. 2014
  9. pmc Deficiency in nucleotide excision repair family gene activity, especially ERCC3, is associated with non-pigmented hair fiber growth
    Mei Yu
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, Canada
    PLoS ONE 7:e34185. 2012
  10. ncbi request reprint Restoration of hair growth with topical diphencyprone in mouse and rat models of alopecia areata
    Liren Tang
    Division of Dermatology, University of British Columbia, Vancouver Hospital and Health Sciences Center, 835 W 10th Avenue, Vancouver, BC, Canada V5Z 4E8
    J Am Acad Dermatol 49:1013-9. 2003

Collaborators

Detail Information

Publications50

  1. ncbi request reprint Safety of topical minoxidil solution: a one-year, prospective, observational study
    Jerry Shapiro
    Division of Dermatology, Department of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada
    J Cutan Med Surg 7:322-9. 2003
    ..Topical minoxidil solution (TMS) is widely used for androgenetic alopecia (AGA), and this is the first report of a large safety trial...
  2. ncbi request reprint Alopecia areata: pathogenesis and potential for therapy
    Wei Lu
    Department of Dermatology and Skin Science, University of British Columbia, 835 West 10th Avenue, Vancouver, BC, V5Z 4E8, Canada
    Expert Rev Mol Med 8:1-19. 2006
    ..However, the pathogenetic disease mechanism is particularly robust and the development of a cure for AA will be a significant challenge...
  3. pmc Practical management of hair loss
    J Shapiro
    Division of Dermatology, University of British Columbia UBC, Vancouver
    Can Fam Physician 46:1469-77. 2000
    ..To describe an organized diagnostic approach for both nonscarring and scarring alopecias to help family physicians establish an accurate in-office diagnosis. To explain when ancillary laboratory workup is necessary to confirm the diagnosis...
  4. doi request reprint Lichen planopilaris and pseudopelade of Brocq involve distinct disease associated gene expression patterns by microarray
    Mei Yu
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, Canada
    J Dermatol Sci 57:27-36. 2010
    ..Some suggest LPP and PPB are not distinct diseases, but rather different clinical presentations in a spectrum derived from the same underlying pathogenic mechanism...
  5. doi request reprint Pattern hair loss in men: diagnosis and medical treatment
    Nusrat Banka
    Department of Dermatology and Skin Science, University of British Columbia, 835 West 10th Avenue, Vancouver, BC, Canada
    Dermatol Clin 31:129-40. 2013
    ..The role of sex hormones in females is less understood. This article discusses current understanding of the etiopathogenesis of hair loss in men, diagnostic tests available, and its medical management...
  6. doi request reprint Somatostatin expression in human hair follicles and its potential role in immune privilege
    Trisia Breitkopf
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    J Invest Dermatol 133:1722-30. 2013
    ..Addition of SST antagonists to PBMCs cocultured with allogeneic HF cells increased IFNγ secretion. The data identify SST as a secretory factor potentially contributing to the HF IP repertoire...
  7. doi request reprint Alopecia areata update: part II. Treatment
    Abdullah Alkhalifah
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    J Am Acad Dermatol 62:191-202, quiz 203-4. 2010
    ..It also reviews recently reported experimental treatment options and potential directions for future disease management...
  8. doi request reprint Hair follicle mesenchyme-associated PD-L1 regulates T-cell activation induced apoptosis: a potential mechanism of immune privilege
    Xiaojie Wang
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    J Invest Dermatol 134:736-45. 2014
    ..Our study suggests IP properties are exhibited in cultured DSCCs in part through expression of negative co-signaling molecule PD-L1...
  9. pmc Deficiency in nucleotide excision repair family gene activity, especially ERCC3, is associated with non-pigmented hair fiber growth
    Mei Yu
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, Canada
    PLoS ONE 7:e34185. 2012
    ..This may be due to reduced gene transcription and/or reduced DNA repair in melanocytes which may eventually lead to cell death. These results provide novel information with regard to melanogenesis and its regulation...
  10. ncbi request reprint Restoration of hair growth with topical diphencyprone in mouse and rat models of alopecia areata
    Liren Tang
    Division of Dermatology, University of British Columbia, Vancouver Hospital and Health Sciences Center, 835 W 10th Avenue, Vancouver, BC, Canada V5Z 4E8
    J Am Acad Dermatol 49:1013-9. 2003
    ..The contact sensitizer, diphencyprone (DPCP), is one of the most effective therapies for the more severe forms of alopecia areata (AA)...
  11. ncbi request reprint Interleukin-6 cytokine family member oncostatin M is a hair-follicle-expressed factor with hair growth inhibitory properties
    Mei Yu
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada
    Exp Dermatol 17:12-9. 2008
    ..In principle, increased expression of some IL-6 cytokine family members in cutaneous inflammation might contribute to the promotion of hair loss...
  12. pmc Development of autoimmune hair loss disease alopecia areata is associated with cardiac dysfunction in C3H/HeJ mice
    Eddy Wang
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada
    PLoS ONE 8:e62935. 2013
    ..In conclusion, murine AA is associated with structural, biochemical, and gene expression changes consistent with cardiac hypertrophy in response to ACTH exposure...
  13. doi request reprint Hair transplantation update: procedural techniques, innovations, and applications
    M J Kristine Bunagan
    Department of Dermatology and Skin Science, University of British Columbia, 835 West 10th Avenue, Vancouver, British Columbia, Canada
    Dermatol Clin 31:141-53. 2013
    ..In addition, there is ongoing expansion of the indications and applications of this procedure beyond the usual male pattern hair loss...
  14. ncbi request reprint Lichen planopilaris
    Hoon Kang
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    Dermatol Ther 21:249-56. 2008
    ..Although there are no definitive curative modalities, some new discoveries and conceptual advances continue to broaden our treatment options of this complex condition...
  15. ncbi request reprint Pseudopelade of Brocq
    Abdullateef A Alzolibani
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    Dermatol Ther 21:257-63. 2008
    ..Controversial opinions still exist as to whether PPB is a single entity or an end stage of several cicatricial alopecic disorders. A practical approach to diagnosis of PPB and therapeutic update are discussed in this review...
  16. ncbi request reprint Androgens and hair loss
    Adel Alsantali
    Department of Dermatology and Skin Science, University of British Columbia, British Columbia, Canada
    Curr Opin Endocrinol Diabetes Obes 16:246-53. 2009
    ..Many advances in the pathogenesis and treatment of AGA have been discovered recently. We discuss the pathogenesis and treatment of AGA...
  17. doi request reprint Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis
    Abdullah Alkhalifah
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    J Am Acad Dermatol 62:177-88, quiz 189-90. 2010
    ..Part one of this two-part series on AA describes the clinical presentation and the associated histopathologic picture. It also proposes a hypothesis for AA development based on the most recent knowledge of disease pathogenesis...
  18. pmc CXCR3/ligands are significantly involved in the tumorigenesis of basal cell carcinomas
    Blanche Ka Ki Lo
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Pathol 176:2435-46. 2010
    ....
  19. ncbi request reprint Old wine in new bottles: reviving old therapies for alopecia areata using rodent models
    Liren Tang
    Division of Dermatology, University of British Columbia, Vancouver, Canada
    J Investig Dermatol Symp Proc 8:212-6. 2003
    ..These visible, accessible, and unilaterally treated animal model systems are ideal for studying novel alopecia areata therapies, particularly in terms of their in vivo molecular mechanisms of action...
  20. ncbi request reprint Diagnosis and management of primary cicatricial alopecia: part II
    Wen Yu Wu
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada
    Skinmed 7:78-83. 2008
    ....
  21. doi request reprint Uncombable hair syndrome
    Pamela Calderon
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    J Am Acad Dermatol 61:512-5. 2009
    ..The majority of cases are inherited in an autosomal-dominant manner with either complete or incomplete penetrance. There is no definitive treatment, and most cases improve with the onset of puberty...
  22. ncbi request reprint A randomized bilateral vehicle-controlled study of eflornithine cream combined with laser treatment versus laser treatment alone for facial hirsutism in women
    Iltefat Hamzavi
    Department of Dermatology and Skin Science, University of British Columbia and the Vancouver Coastal Health Research Institute, British Columbia, Canada
    J Am Acad Dermatol 57:54-9. 2007
    ..This study was designed to determine whether topical eflornithine can enhance the efficacy of laser hair removal...
  23. ncbi request reprint Update on primary cicatricial alopecias
    Elizabeth K Ross
    Department of Medicine, University of British Columbia, Vancouver Coastal Health Research Insitute, Vancouver, British Columbia, Canada
    J Am Acad Dermatol 53:1-37; quiz 38-40. 2005
    ..Details of classification, etiopathogenesis, clinicopathologic features, differential diagnosis, and practical management of the primary cicatricial alopecias will be discussed...
  24. ncbi request reprint Topical mechlorethamine restores autoimmune-arrested follicular activity in mice with an alopecia areata-like disease by targeting infiltrated lymphocytes
    Liren Tang
    Division of Dermatology, Department of Surgery, University of British Columbia and Vancouver General Hospital, Vancouver, Canada
    J Invest Dermatol 120:400-6. 2003
    ..Our findings support that mechlorethamine restores follicular activity by selectively targeting infiltrated lymphocytes in vivo in alopecia-areata-affected mice...
  25. ncbi request reprint Examining the relationship between alopecia areata, androgenetic alopecia, and emotional intelligence
    Assaf Monselise
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, Canada
    J Cutan Med Surg 17:46-51. 2013
    ..Emotional intelligence (EI), a component of general intelligence, is thought to govern the recognition, expression, and control of stress and other emotions. People with low EI are unable to adequately control stress in everyday life...
  26. doi request reprint Wigs and hairpieces: evaluating dermatologic issues
    Nusrat Banka
    Department of Dermatology, University of British Columbia, Vancouver, British Columbia, Canada
    Dermatol Ther 25:260-6. 2012
    ..We must minimize the distress alopecia can cause by providing up-to-date information to enable them to prepare for and minimize the psychological consequences of hair loss...
  27. ncbi request reprint Rapp-Hodgkin syndrome: a review of the aspects of hair and hair color
    Sung Wook Park
    Division of Dermatology, Vancouver General Hospital, Vancouver, Canada
    J Am Acad Dermatol 53:729-35. 2005
  28. ncbi request reprint Clinical practice. Hair loss in women
    Jerry Shapiro
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, Canada
    N Engl J Med 357:1620-30. 2007
  29. ncbi request reprint Superficial, nodular, and morpheiform basal-cell carcinomas exhibit distinct gene expression profiles
    Mei Yu
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    J Invest Dermatol 128:1797-805. 2008
    ..These data may help us understand the complex behavior of BCC subtypes and may eventually lead to new therapeutic strategies...
  30. ncbi request reprint What can we learn from animal models of Alopecia areata?
    Kevin J McElwee
    Division of Dermatology, University of British Columbia, Vancouver, Canada
    Dermatology 211:47-53. 2005
    ..With a comprehensive understanding of the key elements in AA pathogenesis, new avenues for therapeutic research and intervention will be defined...
  31. ncbi request reprint Cytokines and signal transduction pathways mediated by anthralin in alopecia areata-affected Dundee experimental balding rats
    Liren Tang
    Division of Dermatology, Department of Medicine, University of British Columbia, Vancouver Hospital, Canada
    J Investig Dermatol Symp Proc 8:87-90. 2003
    ..Their potential roles in reversing the autoimmune-arrested follicular activity in Dundee experimental balding rats are discussed...
  32. ncbi request reprint Androgenetic alopecia
    Nina Otberg
    Department of Dermatology and Skin Science, University of British Columbia, 835 West 10th Avenue, Vancouver, BC V5Z 4E8, Canada
    Endocrinol Metab Clin North Am 36:379-98. 2007
    ..Combination with hair restoration surgery leads to best results in suitable candidates. Physicians who specialize in male health issues should be familiar with this common condition and all the available approved treatment options...
  33. ncbi request reprint Use of finasteride in the treatment of men with androgenetic alopecia (male pattern hair loss)
    Jerry Shapiro
    Division of Dermatology, University of British Columbia, Vancouver General Hospital, Vancouver, British Columbia, Canada
    J Investig Dermatol Symp Proc 8:20-3. 2003
    ..This report summarizes the published peer-reviewed literature on the use of finasteride in the treatment of men with AGA, including the data on long-term (5 years) use of finasteride in a placebo-controlled clinical trial environment...
  34. ncbi request reprint Primary cicatricial alopecias: clinicopathology of 112 cases
    Eileen Tan
    Division of Dermatology, University of British Columbia, Vancouver General Hospital, Canada
    J Am Acad Dermatol 50:25-32. 2004
    ..Cicatricial alopecias represent a diverse group of diseases characterized by a lack of follicular ostia and irreversible alopecia. There is limited literature on the epidemiology and therapeutics of cicatricial alopecias...
  35. ncbi request reprint Management of hair loss
    Elizabeth K Ross
    Division of Dermatology, University of British Columbia, Canada
    Dermatol Clin 23:227-43. 2005
    ..This article discusses current agents for the treatment of three commonly encountered nonscarring alopecias: male- and female-pattern hair loss, telogen effluvium, and alopecia areata. Algorithmic approaches to management are provided...
  36. ncbi request reprint Diagnosis and management of primary cicatricial alopecia: part I
    Nina Otberg
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada
    Skinmed 7:19-26. 2008
    ..In part II, the authors will focus on neutrophilic cicatricial alopecias and mixed cicatricial alopecias...
  37. ncbi request reprint Folliculitis decalvans
    Nina Otberg
    Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada
    Dermatol Ther 21:238-44. 2008
    ..Histology displays a mainly neutrophilic inflammatory infiltrate in early lesions and additionally lymphocytes and plasma cells in advanced lesions. Treatment is focused on the eradication of S. aureus anti-inflammatory agents...
  38. ncbi request reprint Paradoxical hypertrichosis after laser epilation
    Abdulmajeed Alajlan
    Division of Dermatology, Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
    J Am Acad Dermatol 53:85-8. 2005
    ..We sought to retrospectively review the prevalence and features of this paradoxical effect...
  39. ncbi request reprint Parametric modeling of narrowband UV-B phototherapy for vitiligo using a novel quantitative tool: the Vitiligo Area Scoring Index
    Iltefat Hamzavi
    Division of Dermatology, Department of Medicine, Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, Canada
    Arch Dermatol 140:677-83. 2004
    ..There is currently no quantitative tool for evaluating vitiligo treatment response using parametric methods...
  40. ncbi request reprint Topical nitrogen mustard in the treatment of alopecia areata: a bilateral comparison study
    Olga Bernardo
    University of British Columbia Hair Research and Treatment Centre, Division of Dermatology, Vancouver General Hospital, Vancouver, Canada
    J Am Acad Dermatol 49:291-4. 2003
    ..We present a preliminary, half-head, controlled 16-week study showing that topical nitrogen mustard was of benefit in 1 of 6 patients treated with 50% to 100% scalp involvement. Another 4 patients did not complete the trial...
  41. ncbi request reprint The expression of insulin-like growth factor 1 in follicular dermal papillae correlates with therapeutic efficacy of finasteride in androgenetic alopecia
    Liren Tang
    Division of Dermatology, The University of British Columbia, Vancouver Hospital, Canada
    J Am Acad Dermatol 49:229-33. 2003
    ..The specific molecular regulators modulated by androgens within hair follicles in the balding scalp are unknown...
  42. ncbi request reprint Evaluation and treatment of male and female pattern hair loss
    Elise A Olsen
    Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Acad Dermatol 52:301-11. 2005
  43. ncbi request reprint Occupational alopecia or alopecia areata?
    Antonella Tosti
    J Am Acad Dermatol 47:636-7. 2002
  44. ncbi request reprint Summary of North American Hair Research Society (NAHRS)-sponsored Workshop on Cicatricial Alopecia, Duke University Medical Center, February 10 and 11, 2001
    Elise A Olsen
    Duke University Medical Center, Durham, North Carolina, USA
    J Am Acad Dermatol 48:103-10. 2003
  45. ncbi request reprint Regeneration of a new hair follicle from the upper half of a human hair follicle in a nude mouse
    Liren Tang
    J Invest Dermatol 119:983-4. 2002
  46. ncbi request reprint Alopecia areata investigational assessment guidelines--Part II. National Alopecia Areata Foundation
    Elise A Olsen
    Duke University Medical Center, Durham, NC 27710, USA
    J Am Acad Dermatol 51:440-7. 2004
  47. ncbi request reprint Secondary cicatricial and other permanent alopecias
    Andreas M Finner
    Trichomed Hair Institute, Berlin, Germany
    Dermatol Ther 21:279-94. 2008
    ..Detection of the underlying disorder may be difficult in end-stage lesions. Treatment is specific for active conditions. Surgery and hair transplantation are options for localized scars...
  48. doi request reprint Cicatricial alopecias
    Jerry Shapiro
    Dermatology and Skin Science University of British Columbia Vancouver, BC, Canada
    Dermatol Ther 21:211. 2008
  49. ncbi request reprint Calcipotriol plus betamethasone dipropionate scalp formulation is effective and well tolerated in the treatment of scalp psoriasis: a phase II study
    Colin Buckley
    Department of Dermatology, Waterford Regional Hospital Ardkeen, Waterford, Ireland
    Dermatology 217:107-13. 2008
    ..There is a need for more effective therapy for scalp psoriasis...
  50. ncbi request reprint Lack of efficacy of topical latanoprost in the treatment of eyebrow alopecia areata
    Elizabeth K Ross
    J Am Acad Dermatol 53:1095-6. 2005