U I Schwarz

Summary

Affiliation: University of Western Ontario
Country: Canada

Publications

  1. ncbi Induction of intestinal P-glycoprotein by St John's wort reduces the oral bioavailability of talinolol
    U I Schwarz
    Medical Faculty, Institute of Clinical Pharmacology, Technical University Dresden, Dresden, Germany
    Clin Pharmacol Ther 81:669-78. 2007
  2. ncbi Unexpected effect of verapamil on oral bioavailability of the beta-blocker talinolol in humans
    U I Schwarz
    Institute of Clinical Pharmacology, Faculty of Medicine, University of Technology, Dresden, Germany
    Clin Pharmacol Ther 65:283-90. 1999
  3. ncbi Intestinal drug transporter expression and the impact of grapefruit juice in humans
    H Glaeser
    Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Clin Pharmacol Ther 81:362-70. 2007
  4. ncbi Identification of functionally variant MDR1 alleles among European Americans and African Americans
    R B Kim
    Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    Clin Pharmacol Ther 70:189-99. 2001

Detail Information

Publications4

  1. ncbi Induction of intestinal P-glycoprotein by St John's wort reduces the oral bioavailability of talinolol
    U I Schwarz
    Medical Faculty, Institute of Clinical Pharmacology, Technical University Dresden, Dresden, Germany
    Clin Pharmacol Ther 81:669-78. 2007
    ..Interestingly, the magnitude of induction appeared to be affected by MDR1 genotype...
  2. ncbi Unexpected effect of verapamil on oral bioavailability of the beta-blocker talinolol in humans
    U I Schwarz
    Institute of Clinical Pharmacology, Faculty of Medicine, University of Technology, Dresden, Germany
    Clin Pharmacol Ther 65:283-90. 1999
    ..To quantitate the effect of verapamil administered orally, a calcium channel blocker and potent inhibitor of P-glycoprotein on oral pharmacokinetics of the beta1-adrenergic receptor antagonist talinolol, a substrate of P-glycoprotein...
  3. ncbi Intestinal drug transporter expression and the impact of grapefruit juice in humans
    H Glaeser
    Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    Clin Pharmacol Ther 81:362-70. 2007
    ..Although short-term grapefruit juice ingestion was associated with reduced fexofenadine availability, OATP1A2 or MDR1 expression was unaffected...
  4. ncbi Identification of functionally variant MDR1 alleles among European Americans and African Americans
    R B Kim
    Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA
    Clin Pharmacol Ther 70:189-99. 2001
    ..Thus allelic variation in MDR1 is more common than previously recognized and involves multiple SNPs whose allelic frequencies vary between populations, and some of these SNPs are associated with altered P-glycoprotein function...