Carol Schuurmans


Affiliation: University of Toronto
Country: Canada


  1. Adnani L, Dixit R, Chen X, Balakrishnan A, Modi H, Touahri Y, et al. Plag1 and Plagl2 have overlapping and distinct functions in telencephalic development. Biol Open. 2018;7: pubmed publisher
    ..This article has an associated First Person interview with the first author of the paper. ..
  2. Adnani L, Han S, Li S, Mattar P, Schuurmans C. Mechanisms of Cortical Differentiation. Int Rev Cell Mol Biol. 2018;336:223-320 pubmed publisher
    ..We review herein our current understanding of the intrinsic cues and environmental signals that govern cell fate specification and differentiation decisions during development of neuronal and glial lineages in the murine neocortex. ..
  3. Han S, Dennis D, Balakrishnan A, Dixit R, Britz O, Zinyk D, et al. A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis. Development. 2018;145: pubmed publisher
    ..i>Neurog1 thus employs different mechanisms to temper the pace of early neocortical neurogenesis. ..
  4. Tachibana N, Touahri Y, Dixit R, David L, Adnani L, Cantrup R, et al. Hamartoma-like lesions in the mouse retina: an animal model of Pten hamartoma tumour syndrome. Dis Model Mech. 2018;11: pubmed publisher
    ..This article has an associated First Person interview with the first author of the paper. ..
  5. Dennis D, Han S, Schuurmans C. bHLH transcription factors in neural development, disease, and reprogramming. Brain Res. 2018;: pubmed publisher
    ..These concepts are reviewed herein. ..
  6. Tachibana N, Cantrup R, Dixit R, Touahri Y, Kaushik G, Zinyk D, et al. Pten Regulates Retinal Amacrine Cell Number by Modulating Akt, Tgf?, and Erk Signaling. J Neurosci. 2016;36:9454-71 pubmed publisher
    ..Our studies provide molecular insights into how PTEN loss in humans may lead to uncontrolled cell division in several pathological conditions. ..
  7. Aavani T, Tachibana N, Wallace V, Biernaskie J, Schuurmans C. Temporal profiling of photoreceptor lineage gene expression during murine retinal development. Gene Expr Patterns. 2017;23-24:32-44 pubmed publisher
    ..By characterizing these stages, we have clarified the dynamic nature of gene expression during the period when photoreceptor identities are progressively acquired during development. ..
  8. Dennis D, Wilkinson G, Li S, Dixit R, Adnani L, Balakrishnan A, et al. Neurog2 and Ascl1 together regulate a postmitotic derepression circuit to govern laminar fate specification in the murine neocortex. Proc Natl Acad Sci U S A. 2017;114:E4934-E4943 pubmed publisher
    ..Proneural genes thus act in a context-dependent fashion as early determinants, promoting deep-layer neurogenesis in early cortical progenitors via input into the derepression circuit while also influencing other temporal regulators. ..