Research Topics
| Margaret SampsonSummaryAffiliation: University of Ottawa Country: Canada Publications
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Detail Information
Publications
Assessing the quality of reports of systematic reviews in pediatric complementary and alternative medicineDavid Moher
Thomas C Chalmers Centre for Systematic Reviews, Children s Hospital of Eastern Ontario Research Institute Canada
BMC Pediatr 2:3. 2002..We also examined whether there were differences in the quality of reports of a subset of CAM reviews compared to reviews using conventional interventions...
Shorter courses of parenteral antibiotic therapy do not appear to influence response rates for children with acute hematogenous osteomyelitis: a systematic reviewNicole Le Saux
Department of Pediatrics, University of Ottawa, Ontario, Canada
BMC Infect Dis 2:16. 2002..Currently, there is no consensus on the route and duration of antimicrobial therapy to treat AHO...
An alternative to the hand searching gold standard: validating methodological search filters using relative recallMargaret Sampson
Chalmers Research Group, Children s Hospital of Eastern Ontario Research Institute, Canada
BMC Med Res Methodol 6:33. 2006..We demonstrate the feasibility of using relative recall of included studies from multiple systematic reviews to validate methodological search filters as an alternative to validation against a gold standard formed through hand searching...
Should meta-analysts search Embase in addition to Medline?Margaret Sampson
Chalmers Research Group, Children s Hospital of Eastern Ontario Research Institute, 401 Smyth Road, Ottawa, ON K1H 8L1, Canada
J Clin Epidemiol 56:943-55. 2003..88-0.99). Searching Medline but not Embase risks biasing a meta-analysis by finding studies that show larger estimates, but their prevalence seems low enough that the risk may be slight, provided the rest of the search is comprehensive...
Errors in search strategies were identified by type and frequencyMargaret Sampson
Chalmers Research Group, Children s Hospital of Eastern Ontario Research Institute, Ottawa, Ontario K1H 8L1, Canada
J Clin Epidemiol 59:1057-63. 2006..Errors in the electronic search strategy of a systematic review may undermine the integrity of the evidence base used in the review. We studied the frequency and types of errors in reviews published by the Cochrane Collaboration...
Randomized controlled trials in pediatric complementary and alternative medicine: where can they be found?Margaret Sampson
Chalmers Research Group, Children s Hospital of Eastern Ontario Research Institute, Canada
BMC Pediatr 3:1. 2003..The objective of this study is to identify sources of reported randomized controlled trials (RCTs) in the field of pediatric complementary and alternative medicine (CAM)...
Managing database overlap in systematic reviews using Batch Citation Matcher: case studies using ScopusMargaret Sampson
Chalmers Research Group, Children's Hospital of Eastern Ontario Research Institute, 401 Smyth Road, Ottawa, Ontario K1H 8L1, Canada
J Med Libr Assoc 94:461-3, e219. 2006
Can electronic search engines optimize screening of search results in systematic reviews: an empirical studyMargaret Sampson
Chalmers Research Group, Children s Hospital of Eastern Ontario Research Institute, Ottawa, Canada
BMC Med Res Methodol 6:7. 2006..Our objective is to test the ability of an Ultraseek search engine to rank MEDLINE records of the included studies of Cochrane reviews within the top half of all the records retrieved by the Boolean MEDLINE search used by the reviewers...
Evidence for the effect of omega-3 fatty acids on progression of age-related macular degeneration: a systematic reviewWilliam G Hodge
Department of Ophthalmology, Ottawa Hospital Eye Institute, The University of Ottawa, Ottawa, Ontario, Canada
Retina 27:216-21. 2007....
The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic reviewCatherine Dube
Gastrointestinal Clinical Research Unit, University of Ottawa, Ottawa, Ontario, Canada
Gastroenterology 128:S57-67. 2005..The prevalence is higher still in high-risk groups. Clinicians in a variety of specialties should have a high index of suspicion for the diagnosis of CD and in particular need to pay close attention to the identified high-risk groups...
The diagnostic accuracy of serologic tests for celiac disease: a systematic reviewAlaa Rostom
Gastrointestinal Clinical Research Unit, University of Ottawa, Ottawa, Canada
Gastroenterology 128:S38-46. 2005..If true, the nearly perfect negative predictive value of these tests would drop. The positive predictive value of these tests is likely lower than reported when the tests are applied in low-prevalence populations...
Surveillance search techniques identified the need to update systematic reviewsMargaret Sampson
Chalmers Research Group, Children s Hospital of Eastern Ontario Research Institute, 401 Smyth Road, Ottawa, Ontario K1H 8L1, Canada
J Clin Epidemiol 61:755-62. 2008..This article reports on literature surveillance methods to identify new evidence eligible for updating systematic reviews...
Describing reporting guidelines for health research: a systematic reviewDavid Moher
Ottawa Methods Centre, Clinical Epidemiology Program, Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, Ontario, Canada
J Clin Epidemiol 64:718-42. 2011..To describe the process of development, content, and methods of implementation of reporting guidelines for health research...
Few systematic reviews exist documenting the extent of bias: a systematic reviewAndrea C Tricco
Chalmers Research Group, Children s Hospital of Eastern Ontario Research Institute, 401 Smyth Road, Ottawa, Ontario K1N 6N5, Canada
J Clin Epidemiol 61:422-34. 2008..To summarize the evidence concerning bias and confounding in conducting systematic reviews (SRs)...
Systematic reviews can be produced and published fasterMargaret Sampson
Chalmers Research Group, Children s Hospital of Eastern Ontario Research Institute, Ottawa, Canada
J Clin Epidemiol 61:531-6. 2008....
Sources of evidence to support systematic reviews in librarianshipMargaret Sampson
Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada
J Med Libr Assoc 96:66-9. 2008
Searching for controlled trials of complementary and alternative medicine: a comparison of 15 databasesElise Cogo
Children s Hospital of Eastern Ontario Research Institute, Ottawa, Canada
Evid Based Complement Alternat Med 2011:858246. 2011..Low overlap between databases indicates comprehensive CAM literature searches will require multiple databases...
Assessing the quality of reports of randomized trials in pediatric complementary and alternative medicineDavid Moher
Thomas C Chalmers Centre for Systematic Reviews, Children s Hospital of Eastern Ontario Research Institute, Canada
BMC Pediatr 2:2. 2002..To evaluate the quality of reports of complementary and alternative medicine (CAM) randomized controlled trials (RCTs) in the pediatric population. We also examined whether there was a change in the quality of reporting over time...
Many quality measurements, but few quality measures assessing the quality of breast cancer care in women: a systematic reviewHoward M Schachter
Children s Hospital of Eastern Ontario Research Institute, 401 Smyth Road, Ottawa, ON, Canada
BMC Cancer 6:291. 2006..Quality measurement is essential to monitor effectiveness and to guide improvements in healthcare...
A systematic review identified few methods and strategies describing when and how to update systematic reviewsDavid Moher
Chalmers Research Group, Children s Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada
J Clin Epidemiol 60:1095-1104. 2007..SRs are most helpful if they are current; however, most of them are not being updated. This SR summarizes strategies and methods describing when and how to update SRs...
Oral phosphodiesterase-5 inhibitors and hormonal treatments for erectile dysfunction: a systematic review and meta-analysisAlexander Tsertsvadze
Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
Ann Intern Med 151:650-61. 2009..Erectile dysfunction (ED) is a common male sexual disorder. The relative benefits and harms of pharmacologic therapies for ED, as well as the value of hormonal testing in men with ED, are uncertain...
Epidemiology and reporting characteristics of systematic reviewsDavid Moher
Chalmers Research Group, Children s Hospital of Eastern Ontario Research Institute, Ottawa, Canada
PLoS Med 4:e78. 2007..We set out to capture a representative cross-sectional sample of published SRs and examine them in terms of a broad range of epidemiological, descriptive, and reporting characteristics, including emerging aspects not previously examined...
The use of electronic data capture tools in clinical trials: Web-survey of 259 Canadian trialsKhaled El Emam
Children s Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada
J Med Internet Res 11:e8. 2009..A systematic review of EDC adoption surveys conducted up to 2007 concluded that only 20% of trials are using EDC systems, but previous surveys had weaknesses...
How quickly do systematic reviews go out of date? A survival analysisKaveh G Shojania
Ottawa Health Research Institute, University of Ottawa, Chalmers Research Group, and Children s Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada
Ann Intern Med 147:224-33. 2007..Systematic reviews are often advocated as the best source of evidence to guide clinical decisions and health care policy, yet we know little about the extent to which they require updating...
Efficacy of food fortification on serum 25-hydroxyvitamin D concentrations: systematic reviewSiobhan O'Donnell
Clinical Epidemiology Program, Ottawa Health Research Institute, Ottawa, Canada
Am J Clin Nutr 88:1528-34. 2008..Many residents of the United States and Canada depend on dietary sources of vitamin D to help maintain vitamin D status. Because few natural food sources contain vitamin D, fortified foods may be required...
Updating systematic reviews: an international surveyChantelle Garritty
The Ottawa Methods Centre, Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada
PLoS ONE 5:e9914. 2010..However, little guidance is available about when and how to update SRs. Moreover, the updating policies and practices of organizations that commission or produce SRs are unclear...
Systematic reviews need systematic searchersJessie McGowan
Ottawa Health Research Institute Institute of Population Health University of Ottawa Ottawa K1N 6N5 Canada
J Med Libr Assoc 93:74-80. 2005..This paper will provide a description of the methods, skills, and knowledge of expert searchers working on systematic review teams...
Shifts in the use of population health, health promotion, and public health: a bibliometric analysisAndrea C Tricco
Institute of Population Health, University of Ottawa, Ottawa, ON
Can J Public Health 99:466-71. 2008..The purpose of this research was to compare the use of population health, health promotion, and public health using bibliometric indicators of the published literature...
Identifying null meta-analyses that are ripe for updatingNicholas J Barrowman
Chalmers Research Group, Children s Hospital of Eastern Ontario Research Institute, Ottawa, Canada
BMC Med Res Methodol 3:13. 2003..As an increasingly large number of meta-analyses are published, quantitative methods are needed to help clinicians and systematic review teams determine when meta-analyses are not up to date...
Benefits and harms associated with the practice of bed sharing: a systematic reviewTanya Horsley
Department of Pediatrics, University of Ottawa, and Department of Pediatrics, The Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, Ontario, Canada
Arch Pediatr Adolesc Med 161:237-45. 2007..To examine evidence of benefits and harms to children associated with bed sharing, factors (eg, smoking) altering bed sharing risk, and effective strategies for reducing harms associated with bed sharing...
Guidelines for randomized clinical trial protocol content: a systematic reviewJennifer M Tetzlaff
Ottawa Methods Centre, Ottawa Hospital Research Institute, Smyth Road, Ottawa, Ontario, K1H 8L6, Canada
Syst Rev 1:43. 2012..abstract:..
Effect of point of care information on inpatient management of bronchiolitisW James King
Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada
BMC Pediatr 7:4. 2007..We studied the effects of access to point-of-care medical evidence in a computerised physician order entry system (CPOE) on management and clinical outcome of children with bronchiolitis...
Consequences of testing for celiac diseaseAnn Cranney
Ottawa Health Research Institute, Ottawa, Canada
Gastroenterology 128:S109-20. 2005..The literature suggests that compliance is less than ideal in these individuals, especially if diagnosed when adults. Long-term outcomes have not been extensively studied in those with silent CD...
Intravesical oxybutynin for children with poorly compliant neurogenic bladder: a systematic reviewLuis Antonio Guerra
Division of Pediatric Urology, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ontario, Canada
J Urol 180:1091-7. 2008..They may become nonresponders to the drug or present with severe side effects. We evaluated the effectiveness and tolerability of intravesical oxybutynin in children with poorly compliant neurogenic bladder...
Efficacy of omega-3 fatty acids in preventing age-related macular degeneration: a systematic reviewWilliam G Hodge
Department of Ophthalmology, University of Ottawa Eye Institute, Ottawa, Canada
Ophthalmology 113:1165-72; quiz 1172-3, 1178. 2006..What is the evidence for efficacy of dietary and/or supplemental omega-3 fatty acids in preventing age-related macular degeneration (AMD)?..
Optimizing search strategies to identify randomized controlled trials in MEDLINELi Zhang
Natural Sciences Library, University of Saskatchewan, Saskatoon, Canada
BMC Med Res Methodol 6:23. 2006..The objective of this study is to validate these four revisions: combining the free text terms volunteer, crossover, versus, and the Medical Subject Heading CROSS-OVER STUDIES with the top two phases of the HSSS, respectively...
Breast self-examinationTammy J Clifford
CMAJ 166:164; author reply 166, 168. 2002
Should systematic reviewers search for randomized, controlled trials published as letters?Alla E Iansavichene
Ann Intern Med 148:714-5. 2008
The evidence for efficacy of omega-3 fatty acids in preventing or slowing the progression of retinitis pigmentosa: a systematic reviewWilliam G Hodge
Department of Opthalmology, Ottawa Hospital Eye Institute, University of Ottawa, Ont, Canada
Can J Ophthalmol 41:481-90. 2006....
Selective serotonin reuptake inhibitors for unipolar depression: a systematic review of classic long-term randomized controlled trialsDorian Deshauer
Department of Psychiatry, University of Ottawa, Ottawa, Ont
CMAJ 178:1293-301. 2008..We conducted a systematic review to examine the efficacy and acceptability of long-term therapy with selective serotonin reuptake inhibitors relative to placebo in the treatment of unipolar depression...
No consensus exists on search reporting methods for systematic reviewsMargaret Sampson
Department of Information Studies, University of Wales, Aberystwyth, Wales, UK
J Clin Epidemiol 61:748-54. 2008..The objective of this paper was to identify validated or evaluated search reporting instruments used in reporting systematic review searches and to compare reported and recommended searching practices...
