Research Topics
| Marina SamoilovaSummaryAffiliation: University of Toronto Country: Canada Publications
| Collaborators
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Detail Information
Publications
Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypic hippocampal slice culturesMarina Samoilova
Division of Fundamental Neurobiology, Toronto Western Research Institute, Toronto, Ontario, Canada
Exp Neurol 210:762-75. 2008....
Factors which abolish hypoglycemic seizures do not increase cerebral glycogen content in vitroPeter A Abdelmalik
Division of Fundamental Neurobiology, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
Neurobiol Dis 29:201-9. 2008..The present data suggest that none of the interventions which abolish hypoglycemic seizures increases glycogen content, and that low glycogen content, per se, may not predispose to the generation of hypoglycemic seizures...- Chronic in vitro ketosis is neuroprotective but not anti-convulsantMarina Samoilova
Division of Fundamental Neurobiology, Toronto Western Research Institute, Toronto, Ontario, Canada
J Neurochem 113:826-35. 2010.... - Hippocampal seizures alter the expression of the pannexin and connexin transcriptomeShanthini Mylvaganam
Division of Fundamental Neurobiology, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
J Neurochem 112:92-102. 2010..These data show that seizure activity up-regulates the expression of both glial and neuronal GJ mRNAs and protein while inducing a high degree of coordinate expression of the GJ transcriptome... - Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: increased gap junctional function and expressionMarina Samoilova
Bloorview Epilepsy Research Laboratory, Division of Cellular and Molecular Biology, Toronto Western Research Institute, Toronto, Ontario, Canada
J Neurochem 86:687-99. 2003.... - General anesthetics inhibit gap junction communication in cultured organotypic hippocampal slicesKirsten Wentlandt
Division of Cellular and Molecular Biology, Toronto Western Research Institute, Department of Anesthesia and Pain Management, Physiology, University of Toronto, University Health Network, Toronto, Ontario, Canada
Anesth Analg 102:1692-8. 2006..Suppression of gap junction function could compound the mechanisms of anesthetic actions... - Hypoglycemic seizures during transient hypoglycemia exacerbate hippocampal dysfunctionPeter A Abdelmalik
Division of Fundamental Neurobiology, Toronto Western Research Institute, University Health Network MCL12 413, Toronto Western Hospital, 399 Bathurst St, Toronto, Ontario, 416 603 5040, Canada M5T2S8
Neurobiol Dis 26:646-60. 2007..These data suggest that suppressing seizures during hypoglycemia may decrease subsequent neuronal damage and dysfunction... - Calcium chelation improves spatial learning and synaptic plasticity in aged ratsAlexander Tonkikh
Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada
Exp Neurol 197:291-300. 2006..These results support the hypothesis that increasing intracellular neuronal buffering power for calcium in aged rats ameliorates age-related impaired synaptic plasticity and learning... - Visualization of cytoplasmic diffusion within living myelin sheaths of CNS white matter axons using microinjection of the fluorescent dye Lucifer YellowAlexander A Velumian
Division of Genetics and Development, Toronto Western Research Institute, Canada
Neuroimage 56:27-34. 2011..Our findings point to an elaborate cytoplasmic access to compact CNS myelin. These results could be of relevance to MRI studies of CNS white matter and to CNS repair/regeneration strategies... - Contribution of fast and slow conducting myelinated axons to single-peak compound action potentials in rat spinal cord white matter preparationsAlexander A Velumian
Division of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, ON M5T 2S8, Canada
J Neurophysiol 105:929-41. 2011....