D N Rush

Summary

Affiliation: University of Manitoba
Country: Canada

Publications

  1. ncbi request reprint Protocol transplant biopsies: an underutilized tool in kidney transplantation
    David Rush
    University of Manitoba and Manitoba Adult Renal Transplant Program, Winnipeg, Manitoba, Canada
    Clin J Am Soc Nephrol 1:138-43. 2006
  2. ncbi request reprint Does subclinical rejection contribute to chronic rejection in renal transplant patients?
    D N Rush
    Department of Medicine, University of Manitoba, Winnipeg, Canada
    Clin Transplant 13:441-6. 1999
  3. doi request reprint Five-year study of tacrolimus as secondary intervention versus continuation of cyclosporine in renal transplant patients at risk for chronic renal allograft failure
    Anthony Jevnikar
    London Health Sciences Centre, University Campus, London, ON, Canada
    Transplantation 86:953-60. 2008
  4. doi request reprint The impact of calcineurin inhibitors on graft survival
    David Rush
    Department of Internal Medicine, University of Manitoba, Winnipeg, MB R3A 1R9, Canada
    Transplant Rev (Orlando) 27:93-5. 2013
  5. ncbi request reprint Insights into subclinical rejection
    D Rush
    Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    Transplant Proc 36:71S-73S. 2004
  6. ncbi request reprint Lack of benefit of early protocol biopsies in renal transplant patients receiving TAC and MMF: a randomized study
    D Rush
    Health Sciences Centre, Winnipeg, Manitoba, Canada
    Am J Transplant 7:2538-45. 2007
  7. ncbi request reprint Factors associated with progression of interstitial fibrosis in renal transplant patients receiving tacrolimus and mycophenolate mofetil
    David N Rush
    Department of Internal Medicine, Health Sciences Centre, Winnipeg, MB, Canada R3A 1R9
    Transplantation 88:897-903. 2009
  8. ncbi request reprint Protocol biopsies for renal transplantation
    David Rush
    University of Manitoba, Faculty of Medicine, Department of Internal Medicine, Section of Nephrology, Health Sciences Centre, Winnipeg, MB, Canada
    Saudi J Kidney Dis Transpl 21:1-9. 2010
  9. ncbi request reprint Protocol biopsies in the management of renal allograft recipients
    D Rush
    Department of Medicine, University of Manitoba, Canada
    Curr Opin Nephrol Hypertens 9:615-9. 2000
  10. ncbi request reprint Class II HLA epitope matching-A strategy to minimize de novo donor-specific antibody development and improve outcomes
    C Wiebe
    Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada Department of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada
    Am J Transplant 13:3114-22. 2013

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Protocol transplant biopsies: an underutilized tool in kidney transplantation
    David Rush
    University of Manitoba and Manitoba Adult Renal Transplant Program, Winnipeg, Manitoba, Canada
    Clin J Am Soc Nephrol 1:138-43. 2006
  2. ncbi request reprint Does subclinical rejection contribute to chronic rejection in renal transplant patients?
    D N Rush
    Department of Medicine, University of Manitoba, Winnipeg, Canada
    Clin Transplant 13:441-6. 1999
    ....
  3. doi request reprint Five-year study of tacrolimus as secondary intervention versus continuation of cyclosporine in renal transplant patients at risk for chronic renal allograft failure
    Anthony Jevnikar
    London Health Sciences Centre, University Campus, London, ON, Canada
    Transplantation 86:953-60. 2008
    ..This study tested the hypothesis that conversion from cyclosporine to tacrolimus might improve long-term outcomes in patients with chronic allograft damage...
  4. doi request reprint The impact of calcineurin inhibitors on graft survival
    David Rush
    Department of Internal Medicine, University of Manitoba, Winnipeg, MB R3A 1R9, Canada
    Transplant Rev (Orlando) 27:93-5. 2013
    ....
  5. ncbi request reprint Insights into subclinical rejection
    D Rush
    Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    Transplant Proc 36:71S-73S. 2004
    ..Although a decrease in the prevalence of subclinical rejection may reduce the rate of late graft losses, the risks and cost of protocol biopsies require that noninvasive methods for the diagnosis of subclinical rejection be developed...
  6. ncbi request reprint Lack of benefit of early protocol biopsies in renal transplant patients receiving TAC and MMF: a randomized study
    D Rush
    Health Sciences Centre, Winnipeg, Manitoba, Canada
    Am J Transplant 7:2538-45. 2007
    ..This is likely due to their low prevalence of subclinical rejection...
  7. ncbi request reprint Factors associated with progression of interstitial fibrosis in renal transplant patients receiving tacrolimus and mycophenolate mofetil
    David N Rush
    Department of Internal Medicine, Health Sciences Centre, Winnipeg, MB, Canada R3A 1R9
    Transplantation 88:897-903. 2009
    ..We report on the follow-up of these patients to 24 months at which time a repeat PBx and tests of renal function were performed...
  8. ncbi request reprint Protocol biopsies for renal transplantation
    David Rush
    University of Manitoba, Faculty of Medicine, Department of Internal Medicine, Section of Nephrology, Health Sciences Centre, Winnipeg, MB, Canada
    Saudi J Kidney Dis Transpl 21:1-9. 2010
    ..However, we believe that until such methods have been developed and validated, the protocol biopsy will remain an indispensable tool for the complete care of renal transplant patients...
  9. ncbi request reprint Protocol biopsies in the management of renal allograft recipients
    D Rush
    Department of Medicine, University of Manitoba, Canada
    Curr Opin Nephrol Hypertens 9:615-9. 2000
    ..Recent studies in the areas of 'marginal' donors, surveillance of acute rejection, molecular biology and chronic rejection are discussed...
  10. ncbi request reprint Class II HLA epitope matching-A strategy to minimize de novo donor-specific antibody development and improve outcomes
    C Wiebe
    Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada Department of Immunology, University of Manitoba, Winnipeg, Manitoba, Canada
    Am J Transplant 13:3114-22. 2013
    ..HLA-DR and DQ epitope matching outperforms traditional low-resolution antigen-based matching and has the potential to minimize the risk of de novo Class II DSA development, thereby improving long-term graft outcome...
  11. ncbi request reprint Quantitation of allograft fibrosis and chronic allograft nephropathy
    P C Grimm
    Department of Pediatrics, University of Manitoba, Winnipeg, Canada
    Pediatr Transplant 3:257-70. 1999
    ..These methods, performed at different times post-transplant, are reviewed in this article. In particular, pathology scoring systems and the potential of using computerized image analysis of biopsy material are discussed...
  12. ncbi request reprint Matching for private or public HLA epitopes reduces acute rejection episodes and improves two-year renal allograft function
    R M McKenna
    Department of Internal Medicine, Health Sciences Centre and The University of Manitoba, Winnipeg, Canada
    Transplantation 66:38-43. 1998
    ..Public HLA epitope matching has been suggested to be as advantageous as private HLA matching, with the added benefit of increasing recipients' access to well-matched grafts...
  13. doi request reprint Evolution and clinical pathologic correlations of de novo donor-specific HLA antibody post kidney transplant
    C Wiebe
    Department of Medicine and Immunology, University of Manitoba, Canada
    Am J Transplant 12:1157-67. 2012
    ....
  14. ncbi request reprint Clinical rejection is distinguished from subclinical rejection by increased infiltration by a population of activated macrophages
    P C Grimm
    Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Canada
    J Am Soc Nephrol 10:1582-9. 1999
    ..014) increased in the infiltrate of clinical rejection biopsies. These data suggest that activated macrophages or their products are responsible for acute renal dysfunction associated with clinical rejection episodes...
  15. ncbi request reprint Kidney transplantation outcomes in Canadian aboriginals
    C L C Weber
    Department of Medicine, Section of Nephrology, University of British Columbia, Vancouver, Canada
    Am J Transplant 6:1875-81. 2006
    ..In conclusion, kidney transplant outcomes have historically been inferior in the Manitoba population of Canadian Aboriginals...
  16. ncbi request reprint Protocol biopsies should be part of the routine management of kidney transplant recipients. Pro
    David Rush
    Winnipeg Transplant Program Winnipeg, Manitoba, Canada
    Am J Kidney Dis 40:671-3. 2002
  17. ncbi request reprint Heightened peripheral blood lymphocyte CD69 expression is neither sensitive nor specific as a noninvasive diagnostic test for renal allograft rejection
    Martin Karpinski
    Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    J Am Soc Nephrol 14:226-33. 2003
    ..This latter finding suggests that clinically inapparent CMV viremia may be a potential confounder for biomarkers of rejection that examine peripheral blood lymphocytes...
  18. ncbi request reprint The urine protein to creatinine ratio (P/C) as a predictor of 24-hour urine protein excretion in renal transplant patients
    S Torng
    Faculty of Medicine, University of Manitoba, Health Sciences Centre, 820 Sherbrook Street, GE 441, Winnepeg, MB/R3A IR9, Canada
    Transplantation 72:1453-6. 2001
    ..7555, P<0.0001). CONCLUSION: We conclude that the urine P/C ratio is a useful and convenient screening and longitudinal test for proteinuria...
  19. ncbi request reprint The relative importance of cytokine gene polymorphisms in the development of early and late acute rejection and six-month renal allograft pathology
    Kathryn Tinckam
    Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    Transplantation 79:836-41. 2005
    ..Acute rejection episodes and 6-month protocol biopsy acute pathology are highly correlated with long-term outcomes in renal transplant recipients. Recurrent, vascular, and late rejections are particularly deleterious...
  20. ncbi request reprint Proteomic-based identification of cleaved urinary beta2-microglobulin as a potential marker for acute tubular injury in renal allografts
    Stefan Schaub
    Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada
    Am J Transplant 5:729-38. 2005
    ..These factors ultimately lead to increased amounts of cleaved urinary beta2-microglobulin. Cleaved beta2-microglobulin as an indicator of acute tubular injury may become a useful tool for noninvasive monitoring of renal allografts...
  21. ncbi request reprint Reproducibility of the Banff schema in reporting protocol biopsies of stable renal allografts
    James Gough
    Department of Pathology, University of Manitoba Health Sciences Centre, Winnipeg, Manitoba, Canada
    Nephrol Dial Transplant 17:1081-4. 2002
    ..However, the reproducibility of such histological evaluation has not been tested in this setting. We tested the reproducibility of the Banff schema for this purpose...
  22. ncbi request reprint Proteomic-based detection of urine proteins associated with acute renal allograft rejection
    Stefan Schaub
    Faculty of Medicine, University of Manitoba, and Manitoba Centre for Proteomics, Winnipeg, Manitoba, Canada
    J Am Soc Nephrol 15:219-27. 2004
    ..Identification of these proteins may prove useful as non-invasive diagnostic markers for rejection and the development of novel therapeutic agents...
  23. ncbi request reprint Late recurrence of scleroderma renal crisis in a renal transplant recipient despite angiotensin II blockade
    Winson Y Cheung
    Department of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    Am J Kidney Dis 45:930-4. 2005
    ....
  24. ncbi request reprint Developing a tool for noninvasive monitoring of renal allografts
    Stefan Schaub
    University Hospital Basel, Department for Transplantation Immunology and Nephrology, Petersgraben 4, 4031 Basel, Switzerland
    Expert Rev Proteomics 3:497-509. 2006
    ....
  25. ncbi request reprint Long-term deterioration of kidney allograft function
    Bertram L Kasiske
    Department of Medicine, University of Minnesota, Minneapolis, USA
    Am J Transplant 5:1405-14. 2005
    ..78 (0.64-0.95), p = 0.0110 during 1999-2002 (compared to 1984-1989). We conclude that the rate of decline in allograft function after kidney transplantation has improved, suggesting that stable, long-term function may be achievable...
  26. ncbi request reprint Detection of subclinical tubular injury after renal transplantation: comparison of urine protein analysis with allograft histopathology
    Stefan Schaub
    Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland
    Transplantation 84:104-12. 2007
    ..This study investigated whether urinary tubular injury biomarkers can detect subclinical tubulitis found in protocol biopsies allowing for a noninvasive screening procedure...
  27. ncbi request reprint Management of the waiting list for cadaveric kidney transplants: report of a survey and recommendations by the Clinical Practice Guidelines Committee of the American Society of Transplantation
    Gabriel M Danovitch
    Division of Nephrology, University of California, Los Angeles, School of Medicine, Los Angeles, California 90025, USA
    J Am Soc Nephrol 13:528-35. 2002
    ....
  28. pmc Canadian Society of Transplantation consensus guidelines on eligibility for kidney transplantation
    Greg Knoll
    Division of Nephrology, University of Ottawa and The Ottawa Hospital, Ottawa, Ont
    CMAJ 173:1181-4. 2005
  29. pmc Canadian Society of Transplantation: consensus guidelines on eligibility for kidney transplantation
    Greg Knoll
    Division of Nephrology, The Ottawa Hospital, Ottawa, Ont
    CMAJ 173:S1-25. 2005