Research Topics
Species | Lindsay E RobinsonSummaryAffiliation: University of Guelph Country: Canada Publications
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Publications
Insulin resistance and hyperglycemia in critical illness: role of insulin in glycemic controlLindsay E Robinson
Department of Human Biology and Nutrition Sciences, University of Guelph, Guelph, ON, Canada
AACN Clin Issues 15:45-62. 2004..The article addresses the application of insulin protocols and exogenous regulation of glucose concentration in critical illness based on a review of recent intervention studies...
N-3 polyunsaturated fatty acids: relationship to inflammation in healthy adults and adults exhibiting features of metabolic syndromeLindsay E Robinson
Department of Human Health and Nutritional Sciences, Room 336 B Animal Science and Nutrition Building, University of Guelph, Guelph, ON N1G 2W1, Canada
Lipids 48:319-32. 2013..Overall, the data reviewed herein support recommendations for regular fatty fish consumption and point toward health benefits in terms of lowering inflammation in adults with one or more features of MetS...- Caffeine ingestion before an oral glucose tolerance test impairs blood glucose management in men with type 2 diabetesLindsay E Robinson
Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, ON, Canada
J Nutr 134:2528-33. 2004.... - Fasting triacylglycerol status, but not polyunsaturated/saturated fatty acid ratio, influences the postprandial response to a series of oral fat tolerance testsMark J Dekker
Department of Human Health and Nutritional Sciences, University of Guelph, ON, Canada
J Nutr Biochem 20:694-704. 2009..However, P/S ratio had no influence on postprandial lipid and inflammatory parameters... - Consumption of caffeinated coffee and a high carbohydrate meal affects postprandial metabolism of a subsequent oral glucose tolerance test in young, healthy malesLesley L Moisey
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada
Br J Nutr 103:833-41. 2010..4 (sem 1.4), P < 0.001). Co-ingestion of CC with one meal resulted in insulin insensitivity during the postprandial phase of a second meal in the absence of further CC ingestion. Thus, CC may play a role in daily glycaemic management... - Lifestyle factors increasing adiponectin synthesis and secretionJustine M Tishinsky
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
Vitam Horm 90:1-30. 2012.... - Vaccenic acid in serum triglycerides is associated with markers of insulin resistance in menMichael A Zulyniak
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada
Appl Physiol Nutr Metab 37:1003-7. 2012..Moreover, vaccenic acid levels were positively correlated with insulin and HOMA-IR. This reinforces that examination of individual FA in the context of insulin resistance is warranted... - Modifying the n-6/n-3 polyunsaturated fatty acid ratio of a high-saturated fat challenge does not acutely attenuate postprandial changes in inflammatory markers in men with metabolic syndromeHilary M F Tulk
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G 2W1
Metabolism 58:1709-16. 2009..Thus, increasing the n-3 PUFA content of a high-SFA OFTT does not acutely change postprandial TAG or inflammatory responses in men with MetS... - An oral lipid challenge and acute intake of caffeinated coffee additively decrease glucose tolerance in healthy menMarie Soleil Beaudoin
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada
J Nutr 141:574-81. 2011..05). These results show that oral consumption of lipids and caffeinated coffee can independently and additively decrease glucose tolerance. Incretin hormones could explain at least in part this impaired glucose homeostasis... - Acute caffeine ingestion and glucose tolerance in women with or without gestational diabetes mellitusLindsay E Robinson
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
J Obstet Gynaecol Can 31:304-12. 2009..The current study sought to assess the effect of acute caffeine ingestion on glucose tolerance in women with or without gestational diabetes mellitus (GDM)... - Influence of interesterification of a stearic acid-rich spreadable fat on acute metabolic risk factorsDawn M Robinson
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada
Lipids 44:17-26. 2009..05). The differences in TAG response between non-obese and obese subjects suggest that interesterification may affect healthy individuals differently compared to those already at risk for T2D and/or CVD... - The acute impact of ingestion of breads of varying composition on blood glucose, insulin and incretins following first and second mealsAnita Mofidi Najjar
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada
Br J Nutr 101:391-8. 2009.... - New oral fat tolerance tests feature tailoring of the polyunsaturated/saturated fatty acid ratio to elicit a specific postprandial responseMark J Dekker
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada
Appl Physiol Nutr Metab 32:1073-81. 2007..05) during their respective postprandial periods. We concluded that blood TAGs are elevated in a specific pattern through the administration of novel OFTTs with specific P/S blends without eliciting an insulin or glucose response... - Caffeinated coffee consumption impairs blood glucose homeostasis in response to high and low glycemic index meals in healthy menLesley L Moisey
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
Am J Clin Nutr 87:1254-61. 2008..The ingestion of caffeine (5 mg/kg body weight) and a 75-g oral glucose load has been shown to elicit an acute insulin-insensitive environment in healthy and obese individuals and in those with type 2 diabetes... - Glucose homeostasis remains altered by acute caffeine ingestion following 2 weeks of daily caffeine consumption in previously non-caffeine-consuming malesMark J Dekker
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G 2W1
Br J Nutr 98:556-62. 2007..05) on day 14 v. day 0. Although 14 d of caffeine consumption by previously caffeine-naive subjects reduced its impact on glucose homeostasis, carbohydrate metabolism remained disrupted... - Exercise prior to fat ingestion lowers fasting and postprandial VLDL and decreases adipose tissue IL-6 and GIP receptor mRNA in hypertriacylglycerolemic menMark J Dekker
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G 2W1
J Nutr Biochem 21:983-90. 2010..Our results suggest that the reduction in VLDL TAG following an acute bout of exercise is not associated with circulating IL-6 or incretin concentrations, despite reductions in the adipose tissue expression of IL-6 and GIPr... - Fish oil prevents high-saturated fat diet-induced impairments in adiponectin and insulin response in rodent soleus muscleJustine M Tishinsky
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
Am J Physiol Regul Integr Comp Physiol 302:R598-605. 2012..05). Our results demonstrate that fish oil can prevent high SFA diet-induced impairments in both Ad and insulin response in soleus muscle... - n-3 polyunsaturated fatty acids increase thermic effect of food in men with metabolic syndromeKelly M Matheson
Department of Human Health and Nutritional Sciences, University of Guelph, ON
Can J Diet Pract Res 72:201-4. 2011..Effects on energy metabolism of a test meal and a two-week dietary intervention were observed in men with metabolic syndrome (MetS). Both the meal and the intervention included foods containing fish-derived n-3 polyunsaturated fats (PUFA)... - Acute ingestion of long-chain (n-3) polyunsaturated fatty acids decreases fibrinolysis in men with metabolic syndromeCamilla Montegaard
Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, Frederiksberg C 1870, Denmark 4Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada, N1G 2W1
J Nutr 140:38-43. 2010..Overall, acute intake of a high (n-3)LCPUFA beverage shifted the balance between plasma PAI-1 and t-PA, which might indicate a lower capacity for fibrinolysis... - Inflammation, obesity, and fatty acid metabolism: influence of n-3 polyunsaturated fatty acids on factors contributing to metabolic syndromeLindsay E Robinson
Department of Human Health and Nutritional Sciences, Room 336 B Animal Science and Nutrition Building, University of Guelph, Guelph, ON N1G 2W1, Canada
Appl Physiol Nutr Metab 32:1008-24. 2007.... - Skeletal muscle inflammation is not responsible for the rapid impairment in adiponectin response with high-fat feeding in ratsKerry L Mullen
Dept of Human Health and Nutritional Sciences, Univ of Guelph, Ontario, Canada, N1G 2W1
Am J Physiol Regul Integr Comp Physiol 299:R500-8. 2010..Surprisingly, aspirin prevented Ad-stimulated increases in FA oxidation. In conclusion, FA type is critical in the development of Ad resistance, but this does not appear to be mediated by inflammation... - An exercise intervention without weight loss decreases circulating interleukin-6 in lean and obese men with and without type 2 diabetes mellitusMark J Dekker
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G 2W1
Metabolism 56:332-8. 2007.... - Insulin-sensitizing properties of adiponectinJustine M Tishinsky
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada N1G2W1
Biochimie 94:2131-6. 2012..Further research examining the cellular mechanisms underlying the development of adiponectin resistance, and the importance of treating this, needs to be conducted... 
The acute impact of ingestion of sourdough and whole-grain breads on blood glucose, insulin, and incretins in overweight and obese menAnita Mofidi
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada N1G 2W1
J Nutr Metab 2012:184710. 2012..In overweight and obese men, the glycemic response to sprouted grain bread was reduced in both parts 1 and 2 while the other whole-grain test breads did not improve metabolic responses in the acute postprandial state...- Metabolic syndrome, a cardiovascular disease risk factor: role of adipocytokines and impact of diet and physical activityLindsay E Robinson
Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada
Can J Appl Physiol 29:808-29. 2004..This paper will address potential underlying causes of the metabolic syndrome, with a focus on the putative mechanistic role of adipocytokines, and will discuss the impact of diet and physical activity on the metabolic syndrome... - The effect of whole grain wheat sourdough bread consumption on serum lipids in healthy normoglycemic/normoinsulinemic and hyperglycemic/hyperinsulinemic adults depends on presence of the APOE E3/E3 genotype: a randomized controlled trialAmy J Tucker
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada, N1G 2W1
Nutr Metab (Lond) 7:37. 2010..Epidemiological studies associate consumption of whole grain foods, including breads, with reduced cardiovascular disease (CVD) risk; however, few studies have compared wheat whole grains with wheat refined grains... - Eicosapentaenoic acid and rosiglitazone increase adiponectin in an additive and PPARĪ³-dependent manner in human adipocytesJustine M Tishinsky
Department of Human Health and Nutritional Sciences, Animal Science and Nutrition Building, University of Guelph, Guelph, Ontario, Canada
Obesity (Silver Spring) 19:262-8. 2011..Overall, our findings emphasize the therapeutic importance of long-chain n-3 PUFA alone, or in combination with a PPARĪ³ agonist, as a stimulator of adiponectin, a key adipokine involved in obesity and related diseases... - Effect of providing a formula supplemented with long-chain polyunsaturated fatty acids on immunity in full-term neonatesCatherine J Field
Nutrition and Metabolism Research Group, University of Alberta, Edmonton, Alberta T6G 2P5, Canada
Br J Nutr 99:91-9. 2008..Since many diseases have a strong immunological component, these immune changes may be of physiological importance to the developing infant... - Leptin gene expression and systemic levels in healthy men: effect of exercise, carbohydrate, interleukin-6, and epinephrinePernille Keller
Centre of Inflammation and Metabolism, Department of Infectious Diseases and The Copenhagen Muscle Research Center, Faculty of Health Sciences, University Hospital of Copenhagen, Denmark
J Appl Physiol 98:1805-12. 2005..The exercise-induced decrease in circulating leptin was counteracted by CHO ingestion, suggesting a posttranscriptional regulatory mechanism of leptin involving substrate availability... - Epinephrine infusion increases adipose interleukin-6 gene expression and systemic levels in humansPernille Keller
Dept of Infectious Diseases and the Copenhagen Muscle Research Center, Univ Hospital Rigshospitalet, Tagensvej 20, Copenhagen 2200 DK, Denmark
J Appl Physiol 97:1309-12. 2004..001). However, epinephrine did not affect the IL-6 receptor mRNA. In conclusion, epinephrine acutely increases IL-6 mRNA levels in subcutaneous adipose tissue as well as circulating IL-6 levels in healthy men... - The role of dietary long-chain n-3 fatty acids in anti-cancer immune defense and R3230AC mammary tumor growth in rats: influence of diet fat compositionLindsay E Robinson
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada
Breast Cancer Res Treat 73:145-60. 2002..These findings warrant further consideration when designing dietary recommendations...