Joy Richman

Summary

Affiliation: University of British Columbia
Location: Vancouver, Canada
URL: http://www.dentistry.ubc.ca/research/researchers/Richman/
Summary:
Professor, Pediatric Dentistry and Developmental Biology

Publications

  1. doi request reprint Reptilian tooth development
    Joy M Richman
    Department of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada
    Genesis 49:247-60. 2011
  2. doi request reprint Expression and regulation of the decoy bone morphogenetic protein receptor BAMBI in the developing avian face
    Norihisa Higashihori
    Department of Oral Health Sciences, Life Sciences Institute, The University of British Columbia, Vancouver BC, Canada
    Dev Dyn 237:1500-8. 2008
  3. doi request reprint Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb
    Edwina McGlinn
    Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia
    Dev Dyn 237:1172-82. 2008
  4. ncbi request reprint Embryonic development of Python sebae - I: Staging criteria and macroscopic skeletal morphogenesis of the head and limbs
    Julia C Boughner
    Department of Oral Health Sciences, Life Sciences Institute, University of British Columbia, Life Sciences Centre, 2350 Health Sciences Mall, Vancouver, BC, Canada V6T 1Z3
    Zoology (Jena) 110:212-30. 2007
  5. ncbi request reprint Retinoid signaling determines germ cell fate in mice
    Josephine Bowles
    Division of Genetics and Developmental Biology, Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia
    Science 312:596-600. 2006
  6. ncbi request reprint Objective tests of symptom exaggeration in independent medical examinations
    Jack Richman
    AssessMed, Toronto, Canada
    J Occup Environ Med 48:303-11. 2006
  7. ncbi request reprint Cell dissociation experiments reveal that positional information operates in the chicken frontonasal mass
    Masayoshi Kawakami
    Department of Oral and Maxillofacial Surgery, Nara Medical University, Japan
    Genesis 44:105-14. 2006
  8. ncbi request reprint Comparative ontogeny and phylogeny of the upper jaw skeleton in amniotes
    Joy M Richman
    Cellular Mechanisms of Development Group and Department of Oral Health Sciences, Life Sciences Institute, University of British Columbia, Vancouver, B C, Canada
    Dev Dyn 235:1230-43. 2006
  9. ncbi request reprint Control of retinoic acid synthesis and FGF expression in the nasal pit is required to pattern the craniofacial skeleton
    Y Song
    Department of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC, Canada V6T 1Z3
    Dev Biol 276:313-29. 2004
  10. doi request reprint FGF signals from the nasal pit are necessary for normal facial morphogenesis
    Heather L Szabo-Rogers
    Department of Oral Health Sciences, Life Sciences Institute, The University of British Columbia, 2350 Health Sciences Mall, Vancouver BC, Canada
    Dev Biol 318:289-302. 2008

Collaborators

Detail Information

Publications41

  1. doi request reprint Reptilian tooth development
    Joy M Richman
    Department of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada
    Genesis 49:247-60. 2011
    ..Finally, we review the location of label-retaining cells and suggest ways in which these putative dental epithelial stem cells contribute to continuous tooth replacement...
  2. doi request reprint Expression and regulation of the decoy bone morphogenetic protein receptor BAMBI in the developing avian face
    Norihisa Higashihori
    Department of Oral Health Sciences, Life Sciences Institute, The University of British Columbia, Vancouver BC, Canada
    Dev Dyn 237:1500-8. 2008
    ..The data suggested that BAMBI could be used to regulate Bmp signaling during tissue interactions that are an integral part of facial morphogenesis...
  3. doi request reprint Expression of the NET family member Zfp503 is regulated by hedgehog and BMP signaling in the limb
    Edwina McGlinn
    Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia
    Dev Dyn 237:1172-82. 2008
    ..Finally, we demonstrate that posterior expression of Znf503 in the chick limb is responsive to bone morphogenetic protein (BMP) signaling, indicating that Zfp503/Znf503 may act at the nexus of multiple signaling pathways in development...
  4. ncbi request reprint Embryonic development of Python sebae - I: Staging criteria and macroscopic skeletal morphogenesis of the head and limbs
    Julia C Boughner
    Department of Oral Health Sciences, Life Sciences Institute, University of British Columbia, Life Sciences Centre, 2350 Health Sciences Mall, Vancouver, BC, Canada V6T 1Z3
    Zoology (Jena) 110:212-30. 2007
    ..Thus, reptilian animal models will offer unique opportunities for understanding the early influences that contribute to perinatal bone shape...
  5. ncbi request reprint Retinoid signaling determines germ cell fate in mice
    Josephine Bowles
    Division of Genetics and Developmental Biology, Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia
    Science 312:596-600. 2006
    ..Thus, precise regulation of retinoid levels during fetal gonad development provides the molecular control mechanism that specifies germ cell fate...
  6. ncbi request reprint Objective tests of symptom exaggeration in independent medical examinations
    Jack Richman
    AssessMed, Toronto, Canada
    J Occup Environ Med 48:303-11. 2006
    ..This study used the Medical Symptom Validity Test (MSVT) to examine exaggeration of memory impairment in disability claimants...
  7. ncbi request reprint Cell dissociation experiments reveal that positional information operates in the chicken frontonasal mass
    Masayoshi Kawakami
    Department of Oral and Maxillofacial Surgery, Nara Medical University, Japan
    Genesis 44:105-14. 2006
    ..Together, these data suggest that an important patterning mechanism in the face is the ability of mesenchymal cells to sort out according to position and that Msx2 may help repress chondrogenic potential in the lateral frontonasal mass...
  8. ncbi request reprint Comparative ontogeny and phylogeny of the upper jaw skeleton in amniotes
    Joy M Richman
    Cellular Mechanisms of Development Group and Department of Oral Health Sciences, Life Sciences Institute, University of British Columbia, Vancouver, B C, Canada
    Dev Dyn 235:1230-43. 2006
    ..Finally, we discuss how temporal and spatial regulation of preosseous condensations and ossification centers can lead to variation in the morphology of amniote upper jaw bones...
  9. ncbi request reprint Control of retinoic acid synthesis and FGF expression in the nasal pit is required to pattern the craniofacial skeleton
    Y Song
    Department of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC, Canada V6T 1Z3
    Dev Biol 276:313-29. 2004
    ..In addition, our data suggest a novel role for endogenous retinoids from the nasal pit in controlling the precise downregulation of FGF in the center of the frontonasal mass observed during normal vertebrate development...
  10. doi request reprint FGF signals from the nasal pit are necessary for normal facial morphogenesis
    Heather L Szabo-Rogers
    Department of Oral Health Sciences, Life Sciences Institute, The University of British Columbia, 2350 Health Sciences Mall, Vancouver BC, Canada
    Dev Biol 318:289-302. 2008
    ..Coordination of the proliferation in these regions leads ultimately to normal facial morphogenesis...
  11. ncbi request reprint Initiation and patterning of the snake dentition are dependent on Sonic hedgehog signaling
    Marcela Buchtov√°
    Department of Oral Health Sciences, University of British Columbia, Vancouver, BC, Canada
    Dev Biol 319:132-45. 2008
    ..In summary, we have found diverse roles for Shh in patterning the snake dentition but, have excluded the participation of this signal in replacement tooth formation...
  12. doi request reprint Identification of putative dental epithelial stem cells in a lizard with life-long tooth replacement
    Gregory R Handrigan
    Department of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC V6T 1Z3, Canada
    Development 137:3545-9. 2010
    ..Furthermore, their location on the non-tooth-forming side of the dental lamina implies that dental stem cells are sequestered from signals that might otherwise induce them to differentiate...
  13. doi request reprint A network of Wnt, hedgehog and BMP signaling pathways regulates tooth replacement in snakes
    Gregory R Handrigan
    Department of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada
    Dev Biol 348:130-41. 2010
    ....
  14. doi request reprint The function and regulation of TBX22 in avian frontonasal morphogenesis
    Norihisa Higashihori
    Department of Oral Health Sciences, Life Sciences Institute, University of British Columbia, Vancouver, Canada
    Dev Dyn 239:458-73. 2010
    ..Our data suggest that genetic or environmental insults such as those affecting the BMP pathway could lead to a gain-of-function of TBX22 and predispose an individual to cleft lip...
  15. doi request reprint Whole genome microarray analysis of chicken embryo facial prominences
    Marcela Buchtov√°
    Department of Oral Health Sciences, Life Sciences Institute, University of British Columbia, Vancouver, Canada
    Dev Dyn 239:574-91. 2010
    ..Microarrays trends were consistent with the QPCR data for the majority of genes (81%). On the basis of QPCR and microarray data, groups of genes that characterize each of the facial prominences can be determined...
  16. doi request reprint The metalloendopeptidase gene Pitrm1 is regulated by hedgehog signaling in the developing mouse limb and is expressed in muscle progenitors
    Liam Town
    The University of Queensland, Institute for Molecular Bioscience, Queensland, Australia
    Dev Dyn 238:3175-84. 2009
    ..Additionally, Pitrm1 is expressed in Pax3-expressing myoblast progenitors in the limb, the dermomyotome, and developing muscles of the face and torso...
  17. doi request reprint Autocrine and paracrine Shh signaling are necessary for tooth morphogenesis, but not tooth replacement in snakes and lizards (Squamata)
    Gregory R Handrigan
    Department of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada
    Dev Biol 337:171-86. 2010
    ..Finally, in this study, we definitively refute a role for Shh signaling in successional dental lamina formation and conclude that other pathways regulate tooth replacement in squamates...
  18. doi request reprint Expression of WNT signalling pathway genes during chicken craniofacial development
    Poongodi Geetha-Loganathan
    Department of Oral Health Sciences, Life Sciences Institute, The University of British Columbia, Vancouver BC, Canada
    Dev Dyn 238:1150-65. 2009
    ..These data show that activation of the canonical WNT pathway is feasible in all regions of the face; however, the localization of ligands and antagonists confers specificity...
  19. doi request reprint Novel skeletogenic patterning roles for the olfactory pit
    Heather L Szabo-Rogers
    Department of Oral Health Sciences, Life Sciences Institute, The University of British Columbia, Vancouver BC, V6T 1Z3, Canada
    Development 136:219-29. 2009
    ..Thus, the nasal placode has two roles: as a signaling center for the lateral nasal skeleton and as a source of olfactory neurons and sensory epithelium...
  20. ncbi request reprint Upper beak truncation in chicken embryos with the cleft primary palate mutation is due to an epithelial defect in the frontonasal mass
    Mary E MacDonald
    Dalhousie University Medical School, Halifax, Nova Scotia, Canada
    Dev Dyn 230:335-49. 2004
    ..The cpp beak truncation, therefore, is due to an epithelial defect in the frontonasal mass that is coincident with a failure to down-regulate expression of Fgf8...
  21. ncbi request reprint About face: signals and genes controlling jaw patterning and identity in vertebrates
    Joy M Richman
    Department of Oral Health Sciences, University of British Columbia, 2199 Wesbrook Mall, Vancouver, BC, V6T 1Z3 Canada
    Bioessays 25:554-68. 2003
    ..We propose that signals such as retinoids and BMPs and downstream transcription factors such as Distal-less related genes specify jaw identity...
  22. ncbi request reprint Head development. Craniofacial genetics makes headway
    J M Richman
    Department of Clinical Dental Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, Canada
    Curr Biol 5:345-8. 1995
    ..Studies of neural crest migration in animal models, and of human syndromes in which craniofacial development is abnormal, are helping us to understand both prenatal and postnatal development of the head...
  23. ncbi request reprint Epithelia are interchangeable between facial primordia of chick embryos and morphogenesis is controlled by the mesenchyme
    J M Richman
    Department of Anatomy and Developmental Biology, University College and Middlesex School of Medicine, London, England
    Dev Biol 136:201-10. 1989
    ..The form of the recombined graft is determined by the mesenchymal component...
  24. ncbi request reprint Differential growth of facial primordia in chick embryos: responses of facial mesenchyme to basic fibroblast growth factor (bFGF) and serum in micromass culture
    J M Richman
    Department of Anatomy and Developmental Biology, University College, Middlesex School of Medicine, London, UK
    Development 109:341-8. 1990
    ..abstract truncated at 250 words)..
  25. ncbi request reprint A corneal perfusion device for estimating ocular bioavailability in vitro
    J B Richman
    Department of Pharmacokinetics, Allergan, Inc, Irvine, CA 92715
    J Pharm Sci 79:153-7. 1990
    ..The new model opens several potentially useful areas of research into ocular absorption.(ABSTRACT TRUNCATED AT 250 WORDS)..
  26. ncbi request reprint Signals involved in patterning and morphogenesis of the embryonic face
    J M Richman
    Dept of Anatomy and Developmental Biology, U C M S M, London, UK
    Prog Clin Biol Res 373:117-31. 1991
  27. ncbi request reprint Retinoic acid treatment alters the distribution of retinoic acid receptor-beta transcripts in the embryonic chick face
    A Rowe
    Department of Biochemistry, University College and Middlesex School of Medicine, London, UK
    Development 111:1007-16. 1991
    ..In addition, they demonstrate that retinoic acid can induce changes in the pattern of expression of RAR-beta transcripts in vivo...
  28. ncbi request reprint Epithelial-mesenchymal interactions in the outgrowth of limb buds and facial primordia in chick embryos
    J M Richman
    Department of Anatomy and Developmental Biology, University College, Middlesex School of Medicine, London, England
    Dev Biol 154:299-308. 1992
    ..The results suggest that signals employed in the epithelial-mesenchymal interactions in facial primordia are similar but not identical to those signals used in the limb bud...
  29. ncbi request reprint The role of retinoids in normal and abnormal embryonic craniofacial morphogenesis
    J M Richman
    Department of Preventive Dental Science, University of Manitoba, Winnipeg, Canada
    Crit Rev Oral Biol Med 4:93-109. 1992
    ..Finally, the interaction of retinoids with other genes known to be expressed in the face as well as other factors required for facial growth is discussed...
  30. ncbi request reprint Locally released retinoic acid leads to facial clefts in the chick embryo but does not alter the expression of receptors for fibroblast growth factor
    J M Richman
    Department of Clinical Dental Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, Canada
    J Craniofac Genet Dev Biol 15:190-204. 1995
    ..This data suggests that retinoic acid may be affecting other aspects of the FGF receptor-ligand interaction...
  31. ncbi request reprint Craniofacial development: knockout mice take one on the chin
    J Richman
    Department of Clinical Dental Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, Canada
    Curr Biol 6:364-7. 1996
  32. ncbi request reprint Chicken transcription factor AP-2: cloning, expression and its role in outgrowth of facial prominences and limb buds
    H Shen
    Faculty of Dentistry, University of British Columbia, 2199 Wesbrook Mall, Vancouver, British Columbia, V6T 1Z3, Canada
    Dev Biol 188:248-66. 1997
    ..Application of an FGF-4 soaked bead to the apex of the limb bud maintained AP-2 expression. Thus AP-2 is involved in outgrowth and could be regulated by factors such as FGFs that are present in the ectoderm of both the face and limb...
  33. ncbi request reprint Endogenous bone morphogenetic proteins regulate outgrowth and epithelial survival during avian lip fusion
    Amir M Ashique
    Department of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, Vancouver, BC, Canada
    Development 129:4647-60. 2002
    ....
  34. ncbi request reprint Development of the spatial pattern of retinoic acid receptor-beta transcripts in embryonic chick facial primordia
    A Rowe
    Department of Anatomy and Developmental Biology, University College and Middlesex School of Medicine, UK
    Development 114:805-13. 1992
    ..The boundary between these two groups of cells persisted as the maxillary primordia developed.(ABSTRACT TRUNCATED AT 250 WORDS)..
  35. ncbi request reprint Noggin and retinoic acid transform the identity of avian facial prominences
    S H Lee
    Department of Oral Health Science, Faculty of Dentistry, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z3
    Nature 414:909-12. 2001
    ..Thus the levels of Bmp and RA determine whether specific regions of the face form maxillary or frontonasal mass derivatives...
  36. ncbi request reprint Epithelium is required for maintaining FGFR-2 expression levels in facial mesenchyme of the developing chick embryo
    E Matovinovic
    Department of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, Canada
    Dev Dyn 210:407-16. 1997
    ..These results suggest that there are signals in the epithelium required for increasing FGFR-2 and collagen II gene transcription, and the expression of these genes are linked to outgrowth of facial prominences...
  37. ncbi request reprint Expression of fibroblast growth factor receptors (FGFR1, FGFR2, FGFR3) in the developing head and face
    T A Wilke
    Department of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, Canada
    Dev Dyn 210:41-52. 1997
    ..Finally, we discuss the relationship between FGF receptor expression in the chicken and the phenotypes of FGF receptor mutations in humans...
  38. ncbi request reprint Effect of fibroblast growth factors on outgrowth of facial mesenchyme
    J M Richman
    Faculty of Dentistry, University of Manitoba, Winnipeg, R3E 0W2, Canada
    Dev Biol 189:135-47. 1997
    ..Our results indicate that FGFs are part of an endogenous signaling pathway involved in distal outgrowth and chondrogenesis of the facial prominences...
  39. ncbi request reprint Isolation and characterisation of the chick orthologue of the Opitz syndrome gene, Mid1, supports a conserved role in vertebrate development
    Joy M Richman
    Department of Oral Health Sciences, University of British Columbia, Vancouver, Canada
    Int J Dev Biol 46:441-8. 2002
    ..These data indicate that Mid1 plays an evolutionarily conserved developmental function in vertebrates that may involve effects on cellular proliferation, tissue interactions and morphogenesis...
  40. ncbi request reprint Signalling via type IA and type IB bone morphogenetic protein receptors (BMPR) regulates intramembranous bone formation, chondrogenesis and feather formation in the chicken embryo
    Amir M Ashique
    Department of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, Canada
    Int J Dev Biol 46:243-53. 2002
    ..We conclude that the requirement for the type IB is greater than for the type IA receptor but, when active, both receptors play similar roles in regulating bone, cartilage and feather formation in the skull...
  41. ncbi request reprint A new origin for the maxillary jaw
    Sang Hwy Lee
    Department of Oral, Maxillofacial Surgery and Oral Science Research Center, Medical Science and Engineering Research Center, BK 21 Project for Medical Science, College of Dentistry Yonsei University, Seoul, Korea
    Dev Biol 276:207-24. 2004
    ..These data also suggest that during evolution, recession of the first pharyngeal arch-derived palatoquadrate cartilage to a more proximal position gave way to the bony upper jaw of amniotes...