G Prusky

Summary

Affiliation: University of Lethbridge
Country: Canada

Publications

  1. ncbi request reprint Variation in visual acuity within pigmented, and between pigmented and albino rat strains
    Glen T Prusky
    Department of Psychology and Neuroscience, Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, AB, Canada T1K 3M4
    Behav Brain Res 136:339-48. 2002
  2. ncbi request reprint Enhancement of vision by monocular deprivation in adult mice
    Glen T Prusky
    Department of Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada
    J Neurosci 26:11554-61. 2006
  3. ncbi request reprint Rapid quantification of adult and developing mouse spatial vision using a virtual optomotor system
    Glen T Prusky
    Canadian Centre for Behavioural Neuroscience, The University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, Canada T1K 3M4
    Invest Ophthalmol Vis Sci 45:4611-6. 2004
  4. ncbi request reprint Characterization of mouse cortical spatial vision
    G T Prusky
    Department of Psychology and Neuroscience, Canadian Centre for Behavioural Neuroscience, The University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, Canada T1K 3M4
    Vision Res 44:3411-8. 2004
  5. pmc Visual memory task for rats reveals an essential role for hippocampus and perirhinal cortex
    G T Prusky
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, AB, Canada T1K 3M4
    Proc Natl Acad Sci U S A 101:5064-8. 2004
  6. ncbi request reprint Developmental plasticity of mouse visual acuity
    Glen T Prusky
    Canadian Centre for Behavioural Neuroscience, Department of Psychology and Neuroscience, The University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, Canada T1K 3M4
    Eur J Neurosci 17:167-73. 2003
  7. ncbi request reprint Reduced visual acuity impairs place but not cued learning in the Morris water task
    G T Prusky
    Department of Psychology and Neuroscience, The University of Lethbridge, 4401 University Drive, Lethbridge, Alta T1K 3M4, Canada
    Behav Brain Res 116:135-40. 2000
  8. ncbi request reprint Experience-dependent plasticity of visual acuity in rats
    G T Prusky
    Department of Psychology and Neuroscience, The University of Lethbridge, 4401 University Drive, Lethbridge, Alberta T1K 3M4, Canada
    Eur J Neurosci 12:3781-6. 2000
  9. ncbi request reprint Environmental enrichment from birth enhances visual acuity but not place learning in mice
    G T Prusky
    Department of Psychology and Neuroscience, University of Lethbridge, 4401 University Drive, Alta, T1K 3M4, Lethbridge, Canada
    Behav Brain Res 114:11-5. 2000
  10. ncbi request reprint Behavioral assessment of visual acuity in mice and rats
    G T Prusky
    Department of Psychology and Neuroscience, The University of Lethbridge, 4401 University Drive, AB, TIK 3M4, Lethbridge, Canada
    Vision Res 40:2201-9. 2000

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Variation in visual acuity within pigmented, and between pigmented and albino rat strains
    Glen T Prusky
    Department of Psychology and Neuroscience, Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, AB, Canada T1K 3M4
    Behav Brain Res 136:339-48. 2002
    ..Therefore, a consideration of strain differences in visual function should accompany the selection of a rat model for behavioral tasks that involve vision, or when comparing visuo-behavioral measurements across rat strains...
  2. ncbi request reprint Enhancement of vision by monocular deprivation in adult mice
    Glen T Prusky
    Department of Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada
    J Neurosci 26:11554-61. 2006
    ..These data show that the adult mouse visual system maintains a form of experience-dependent plasticity in which the visual cortex can modulate the normal function of subcortical visual pathways...
  3. ncbi request reprint Rapid quantification of adult and developing mouse spatial vision using a virtual optomotor system
    Glen T Prusky
    Canadian Centre for Behavioural Neuroscience, The University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, Canada T1K 3M4
    Invest Ophthalmol Vis Sci 45:4611-6. 2004
    ..To develop a simple, rapid method of quantifying the spatial vision of mice...
  4. ncbi request reprint Characterization of mouse cortical spatial vision
    G T Prusky
    Department of Psychology and Neuroscience, Canadian Centre for Behavioural Neuroscience, The University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, Canada T1K 3M4
    Vision Res 44:3411-8. 2004
    ..The mouse visual system exhibits fundamental mammalian characteristics, including the feature that striate cortex is involved in processing visual information with the highest sensitivity and spatial frequency...
  5. pmc Visual memory task for rats reveals an essential role for hippocampus and perirhinal cortex
    G T Prusky
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, AB, Canada T1K 3M4
    Proc Natl Acad Sci U S A 101:5064-8. 2004
    ..These data demonstrate that rats have a visual recognition memory system fundamentally similar to primates that depends on the function of the hippocampus...
  6. ncbi request reprint Developmental plasticity of mouse visual acuity
    Glen T Prusky
    Canadian Centre for Behavioural Neuroscience, Department of Psychology and Neuroscience, The University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, Canada T1K 3M4
    Eur J Neurosci 17:167-73. 2003
    ..Therefore, the mouse is probably a good model for investigating the basic cellular and molecular mechanisms underlying visual developmental plasticity and amblyopia...
  7. ncbi request reprint Reduced visual acuity impairs place but not cued learning in the Morris water task
    G T Prusky
    Department of Psychology and Neuroscience, The University of Lethbridge, 4401 University Drive, Lethbridge, Alta T1K 3M4, Canada
    Behav Brain Res 116:135-40. 2000
    ..These data indicate that reduced visual acuity in rats can influence measurement of their place learning and that a typical cued platform version of the task cannot detect a modest, but significant, visual deficit...
  8. ncbi request reprint Experience-dependent plasticity of visual acuity in rats
    G T Prusky
    Department of Psychology and Neuroscience, The University of Lethbridge, 4401 University Drive, Lethbridge, Alberta T1K 3M4, Canada
    Eur J Neurosci 12:3781-6. 2000
    ....
  9. ncbi request reprint Environmental enrichment from birth enhances visual acuity but not place learning in mice
    G T Prusky
    Department of Psychology and Neuroscience, University of Lethbridge, 4401 University Drive, Alta, T1K 3M4, Lethbridge, Canada
    Behav Brain Res 114:11-5. 2000
    ..They also indicate that the effects of environmental enrichment are manifested differently in behavioral measures of spatial learning and visual acuity...
  10. ncbi request reprint Behavioral assessment of visual acuity in mice and rats
    G T Prusky
    Department of Psychology and Neuroscience, The University of Lethbridge, 4401 University Drive, AB, TIK 3M4, Lethbridge, Canada
    Vision Res 40:2201-9. 2000
    ..Both mice and rats learn the task quickly. Performance falls below 70% when the spatial frequency is increased beyond 0.5 cycles in most C57BU6 mice, and around 1.0 cycles per degree (cpd) in Long-Evans rats...
  11. ncbi request reprint Serial sectioning of thick tissue with a novel vibrating blade microtome
    G T Prusky
    Department of Psychology and Neuroscience, University of Lethbridge, Alberta, Canada
    Brain Res Brain Res Protoc 3:302-7. 1999
    ..We illustrate the use of this device to identify and reconstruct a column of rat spinal motor neurons retrogradely labeled from a peripheral muscle...
  12. ncbi request reprint Novel method of chronically blocking retinal activity
    G T Prusky
    Department of Psychology and Neuroscience, The University of Lethbridge, Alberta, Canada
    J Neurosci Methods 87:105-10. 1999
    ..The advantages of this procedure over previous methods requiring multiple daily injections of TTX, and alternative experimental applications are discussed...
  13. ncbi request reprint Intracellular filling and reconstruction of identified neurons in fixed rat brain slices
    G Prusky
    Department of Psychology and Neuroscience, University of Lethbridge, Alberta, Canada
    Brain Res Brain Res Protoc 3:313-9. 1999
    ..The cells are filled by iontophoresis, postfixed, and the peroxidase is oxidized into a permanent, opaque reaction product. The dendritic morphology of the neurons is then reconstructed under camera lucida and quantified...
  14. ncbi request reprint Preservation of vision following cell-based therapies in a model of retinal degenerative disease
    T J McGill
    Department of Psychology and Neuroscience, Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive West, Lethbridge, AB, Canada T1K 3M4
    Vision Res 44:2559-66. 2004
    ..These data indicate that the transplantation of cells with very different phenotypes can be used to limit the deterioration of spatial vision in an animal model of retinal degenerative disease...
  15. ncbi request reprint A simple water-immersion condenser for imaging living brain slices on an inverted microscope
    G T Prusky
    Department of Psychology and Neuroscience, University of Lethbridge, Alberta, Canada
    J Neurosci Methods 76:29-33. 1997
    ..When combined with infrared video techniques, this device allows an inverted microscope to effectively image living cells within thick brain slices in an open perfusion chamber...
  16. pmc Ganglion cell adaptability: does the coupling of horizontal cells play a role?
    Karin Dedek
    Department of Neurobiology, University of Oldenburg, Oldenburg, Germany
    PLoS ONE 3:e1714. 2008
    ..This shift is thought to be produced by a change in the ganglion cell receptive field surround, mediated by a decrease in the coupling of horizontal cells...
  17. pmc Retrograde amnesia for visual memories after hippocampal damage in rats
    Jonathan Epp
    Canadian Centre for Behavioural Neuroscience, University of Lethbridge, Lethbridge, Alberta T1K 3M4, Canada
    Learn Mem 15:214-21. 2008
    ..Thus, the hippocampus plays an essential role in long-term memories supporting simple picture discriminations...
  18. ncbi request reprint Intraocular CNTF reduces vision in normal rats in a dose-dependent manner
    Trevor J McGill
    Canadian Centre for Behavioural Neuroscience, The University of Lethbridge, Lethbridge, Alberta, Canada
    Invest Ophthalmol Vis Sci 48:5756-66. 2007
    ..CNTF is a neuroprotective agent for retinal degenerations that can cause reduced electroretinogram (ERG) amplitudes. The goal of the present study was to determine the effects of intraocular delivery of CNTF on normal rat visual function...
  19. ncbi request reprint Syngeneic Schwann cell transplantation preserves vision in RCS rat without immunosuppression
    Trevor J McGill
    Department of Neuroscience, Canadian Centre for Behavioural Neuroscience, University of Lethbridge, 4401 University Drive, Lethbridge, Alberta, Canada
    Invest Ophthalmol Vis Sci 48:1906-12. 2007
    ..To evaluate the efficacy of immunologically compatible Schwann cells transplanted without immunosuppression in the RCS rat retina to preserve vision...
  20. ncbi request reprint Cognitive deficits in rats after forebrain cholinergic depletion are reversed by a novel NO mimetic nitrate ester
    Brian M Bennett
    Department of Pharmacology and Toxicology, Queen s University, Kingston, ON, Canada
    Neuropsychopharmacology 32:505-13. 2007
    ..This approach may be superior to that of current drugs that attempt only to salvage the residual function of damaged cholinergic neurons...
  21. ncbi request reprint Seahorse wins all races: hippocampus participates in both linear and non-linear visual discrimination learning
    Ira Driscoll
    Canadian Centre for Behavioural Neuroscience, Department of Psychology and Neuroscience, University of Lethbridge, Alta
    Behav Brain Res 164:29-35. 2005
    ....
  22. ncbi request reprint Damage to the hippocampal formation does not disrupt representational flexibility as measured by a novelty transfer test
    Ira Driscoll
    Canadian Centre for Behavioural Neuroscience, Psychology and Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada
    Behav Neurosci 118:1427-32. 2004
    ..Eichenbaum, 1992). They are consistent with the view that simple associative processes guide choice behavior in animals with hippocampal damage that are confronted with novel combinations...
  23. ncbi request reprint Recovery of cortical binocularity and orientation selectivity after the critical period for ocular dominance plasticity
    David S Liao
    Dept of Anatomy and Neurobiology, Virginia Commonwealth Univ School of Medicine, 1101 E Marshall St, Sanger Hall Rm 12 042, Richmond VA 23298 0709, USA
    J Neurophysiol 92:2113-21. 2004
    ..Collectively, these results indicate that there is potential for recovery of cortical binocularity and deprived eye orientation selectivity after the end of the critical period for ocular dominance plasticity...
  24. ncbi request reprint Quantification of spatial vision in the Royal College of Surgeons rat
    Trevor J McGill
    Department of Psychology and Neuroscience, University of Lethbridge, Lethbridge, Alberta, Canada
    Invest Ophthalmol Vis Sci 45:932-6. 2004
    ..To examine how spatial vision deteriorates in the RCS rat over time as a background to experimental studies aimed at limiting photoreceptor degeneration...
  25. doi request reprint Experience-dependent plasticity from eye opening enables lasting, visual cortex-dependent enhancement of motion vision
    Glen T Prusky
    Department of Physiology and Biophysics, Weill Cornell Medical College, Burke Medical Research Institute, White Plains, New York 10605, USA
    J Neurosci 28:9817-27. 2008
    ....