Research Topics
Species | Kailash PrasadSummaryAffiliation: University of Saskatchewan Country: Canada Publications
| Collaborators
|
Detail Information
Publications
Effect of flaxseed consumption on blood pressure, serum lipids, hemopoietic system and liver and kidney enzymes in healthy humansCarlo Stuglin
Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
J Cardiovasc Pharmacol Ther 10:23-7. 2005..However, the level of serum triglyceride level was elevated...
Flax lignan complex slows down the progression of atherosclerosis in hyperlipidemic rabbitsKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
J Cardiovasc Pharmacol Ther 14:38-48. 2009..In conclusion, flax lignan complex was effective in slowing down the progression of atherosclerosis by 31%, and this effect was associated with a reduction in oxidative stress...- Natural products in regression and slowing of progression of atherosclerosisKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, 107 Wiggins Road, Saskatoon, SK, S7N 5E5, Canada
Curr Pharm Biotechnol 11:794-800. 2010..SDG slows the progression and regresses established atherosclerosis. FLC does not regress but slows the progression of established atherosclerosis... - Do statins have a role in reduction/prevention of post-PCI restenosis?Kailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada
Cardiovasc Ther 31:12-26. 2013..The future directions for the use of statins in reduction of post-PCI restenosis and myonecrosis have been discussed... - Vitamin E slows the progression of hypercholesterolemia-induced oxidative stress in heart, liver and kidneyKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada
Mol Cell Biochem 368:181-7. 2012.... - A study on regression of hypercholesterolemic atherosclerosis in rabbits by flax lignan complexKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
J Cardiovasc Pharmacol Ther 12:304-13. 2007..These effects of FLC are not associated with reductions in serum lipids and oxidative stress... - Vitamin E does not regress hypercholesterolemic atherosclerosisKailash Prasad
Department of Physiology, University of Saskatchewan, Saskatoon, Canada
J Cardiovasc Pharmacol Ther 14:231-41. 2009..The objectives of this study were to determine if (1) vitamin E regresses hypercholesterolemic atherosclerosis; and (2) regression is associated with reductions in serum lipids and aortic oxidative stress... - Flaxseed and cardiovascular healthKailash Prasad
Department of Physiology, University of Saskatchewan, Saskatoon, Canada
J Cardiovasc Pharmacol 54:369-77. 2009..Flaxseed oil suppresses oxygen radical production by white blood cells, prolongs bleeding time, and in higher doses suppresses serum levels of inflammatory mediators and does not lower serum lipids... - Effects of vitamin E on serum enzymes and electrolytes in hypercholesterolemiaKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, 107 Wiggins Road, Saskatoon SK S7N 5E5, Canada
Mol Cell Biochem 335:67-74. 2010..Hypercholesterolemia for short and long term does not have adverse effects on liver or kidney function, and serum electrolytes. Vitamin E during hypercholesterolemia does not affect serum electrolytes or liver and kidney function... - Effect of chronic administration of vitamin E on the hemopoietic system in hypercholesterolemiaKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada
Mol Cell Biochem 343:67-73. 2010..In conclusion, hypercholesterolemia of short duration has adverse effects on certain elements of the hemopoietic system. Vitamin E does not affect the hemopoietic system during hypercholesterolemia... - Tocotrienols and cardiovascular healthKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, 107 Wiggins Road, Saskatoon SK S7N 5E5, Canada
Curr Pharm Des 17:2147-54. 2011..In conclusion, experimental data suggest that tocotrienols have a potential for cardiovascular health, but long-term randomized clinical trials are needed to establish their efficacy in primary and secondary prevention of CAD... - Regression of hypercholesterolemic atherosclerosis in rabbits by secoisolariciresinol diglucoside isolated from flaxseedKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, 107 Wiggins Road, Saskatoon, Saskatchewan, Canada
Atherosclerosis 197:34-42. 2008.... - Hypocholesterolemic and antiatherosclerotic effect of flax lignan complex isolated from flaxseedKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, 107 Wiggins Road, Saskatoon, Saskatchewan, Canada S7N 5E5
Atherosclerosis 179:269-75. 2005..Lignan complex may, therefore, be beneficial in preventing atherosclerosis, and reducing risk factors for coronary artery disease and stroke... - Suppression of oxidative stress as a mechanism of reduction of hypercholesterolemic atherosclerosis by aspirinKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, Canada
J Cardiovasc Pharmacol Ther 8:61-9. 2003..The purpose of the investigation was to determine if aspirin attenuates the development of hypercholesterolemic atherosclerosis, and if this attenuation is associated with a decrease in the oxidative stress... - Effects of flaxseed oil on serum lipids and atherosclerosis in hypercholesterolemic rabbitsPaul Lee
Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
J Cardiovasc Pharmacol Ther 8:227-35. 2003..The ineffectiveness of flaxseed oil was associated with its ineffectiveness in altering the levels of oxidative stress... - Suppression of hypercholesterolemic atherosclerosis by pentoxifylline and its mechanismKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
Atherosclerosis 192:313-22. 2007.... - Modulation of high sensitivity C-reactive protein by soluble receptor for advanced glycation end productsErick D McNair
Department of Pathology, College of Medicine, University of Saskatchewan and Royal University Hospital, Saskatoon, SK, Canada
Mol Cell Biochem 341:135-8. 2010..The data suggest that sRAGE modulates the synthesis of hs-CRP through TNF-alpha... - Oxidative stress in renal transplant patients who develop cardiovascular diseaseSuzan M G A El-Ghar
Department of Pathology, College of Medicine, University of Saskatchewan, Royal University Hospital, Saskatoon, Saskatchewan, Canada
J Cardiovasc Pharmacol Ther 11:203-10. 2006..Glutathione levels in red blood cells were similar in all 3 groups. Renal transplant recipients without cardiovascular disease have high levels of oxidative stress and may develop cardiovascular disease with time... - Effect of chronic administration of lignan complex isolated from flaxseed on the hemopoietic systemKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, Canada
Mol Cell Biochem 270:139-45. 2005..It is concluded that chronic use of lignan complex had no adverse effects on the hemopoietic system... - C-reactive protein increases oxygen radical generation by neutrophilsKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, S7N 5E5, Canada
J Cardiovasc Pharmacol Ther 9:203-9. 2004..These results suggest that CRP increases the generation of oxygen radicals from the WBCs. CRP-induced atherosclerosis may be mediated through generation of oxygen radicals by neutrophils... 
Attenuated combined action of cyclosporine a and hyperlipidemia on atherogenesis in rabbits by thymoquinoneAhmed Ragheb
Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, SK, Canada
Evid Based Complement Alternat Med 2011:620319. 2011..We concluded that (i) CsA aggravates hyperlipidemia-induced atherosclerosis and (ii) TQ attenuates the oxidative stress and atherogenesis induced by the combined effect of CsA and hyperlipidemia...- Soluble receptors for advanced glycation end products (sRAGE) as a predictor of restenosis following percutaneous coronary interventionErick D McNair
Department of Pathology, College of Medicine, University of Saskatchewan, and Royal University Hospital, Saskatoon, Saskatchewan, Canada
Clin Cardiol 33:678-85. 2010..Balloon-injury-induced atherosclerosis is associated with increased expression of AGEs and RAGE. The soluble receptor for AGE (sRAGE), which acts as a decoy for RAGE ligands (AGEs), prevents atherosclerosis in this model... - Elevated levels of plasma homocysteine in hypertensive patients with diabetes mellitusMabood Qureshi
Department of Pathology, Royal University Hospital, College of Medicine, University of Saskatchewan, Saskatoon, Canada
J Cardiovasc Pharmacol Ther 8:261-6. 2003..CONCLUSIONS: Levels of plasma homocysteine and serum malondialdehyde are elevated in hypertensive diabetic patients. Hyperhomocysteinemia may be involved in the induction and sustaining of hypertension in diabetic patients... - C-reactive protein (CRP)-lowering agentsKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
Cardiovasc Drug Rev 24:33-50. 2006.... - Attenuation of the development of hypercholesterolemic atherosclerosis by thymoquinoneAhmed Ragheb
Department of Medicine, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan
Int J Angiol 17:186-92. 2008..It is concluded that TQ attenuates hypercholesterolemic atherosclerosis and this effect is associated with a decrease in serum lipids and oxidative stress... - Relaxant effect of oxygen free radicals on rabbit tracheal smooth muscleKailash Prasad
Department of Physiology, College of Medicine, University of Saskatchewan, 107 Wiggins Road, Saskatoon, Saskatchewan S7N 5E5, USA
Pulm Pharmacol Ther 15:375-84. 2002..These results suggest that OFRs relax rabbit tracheal smooth muscle. The relaxation appears to be mediated through the synthesis and release of prostaglandins from the epithelium and smooth muscles... - Secoisolariciresinol diglucoside induces neovascularization-mediated cardioprotection against ischemia-reperfusion injury in hypercholesterolemic myocardiumSuresh Varma Penumathsa
Molecular Cardiology and Angiogenesis Laboratory, Department of Surgery, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 1110, USA
J Mol Cell Cardiol 44:170-9. 2008..In conclusion, our study demonstrates for the first time that SDG treatment reduces ventricular remodeling by neovascularization of the infarcted HC myocardium... - Secoisolariciresinol diglucoside: relevance to angiogenesis and cardioprotection against ischemia-reperfusion injurySuresh Varma Penumathsa
Molecular Cardiology and Angiogenesis Laboratory, Department of Surgery, University of Connecticut Health Center, Farmington, CT 06030 1110, USA
J Pharmacol Exp Ther 320:951-9. 2007..In conclusion, these results suggest that SDG has potent angiogenic and antiapoptotic properties that may contribute to its cardioprotective effect in ischemic models...