DonHa Park

Summary

Affiliation: University of British Columbia
Country: Canada

Publications

  1. pmc Repression of a potassium channel by nuclear hormone receptor and TGF-β signaling modulates insulin signaling in Caenorhabditis elegans
    DonHa Park
    Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, Canada
    PLoS Genet 8:e1002519. 2012
  2. pmc Interaction of structure-specific and promiscuous G-protein-coupled receptors mediates small-molecule signaling in Caenorhabditis elegans
    DonHa Park
    Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada, V6T 1Z4
    Proc Natl Acad Sci U S A 109:9917-22. 2012
  3. doi Increased longevity of some C. elegans mitochondrial mutants explained by activation of an alternative energy-producing pathway
    Marco Gallo
    Department of Medical Genetics, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada
    Mech Ageing Dev 132:515-8. 2011
  4. pmc RNAi screen of DAF-16/FOXO target genes in C. elegans links pathogenesis and dauer formation
    Victor L Jensen
    Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 5:e15902. 2010
  5. pmc MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion
    Marco Gallo
    Department of Medical Genetics, The University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 6:e17827. 2011
  6. pmc Antagonistic Smad transcription factors control the dauer/non-dauer switch in C. elegans
    DonHa Park
    Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T1Z4, Canada
    Development 137:477-85. 2010

Detail Information

Publications6

  1. pmc Repression of a potassium channel by nuclear hormone receptor and TGF-β signaling modulates insulin signaling in Caenorhabditis elegans
    DonHa Park
    Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, Canada
    PLoS Genet 8:e1002519. 2012
    ..elegans. NHR-69 and DAF-8 dependent regulation of exp-2 and DAF-28 also provides a novel molecular mechanism that contributes to the previously recognized link between insulin and TGF-β signaling in C. elegans...
  2. pmc Interaction of structure-specific and promiscuous G-protein-coupled receptors mediates small-molecule signaling in Caenorhabditis elegans
    DonHa Park
    Michael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada, V6T 1Z4
    Proc Natl Acad Sci U S A 109:9917-22. 2012
    ....
  3. doi Increased longevity of some C. elegans mitochondrial mutants explained by activation of an alternative energy-producing pathway
    Marco Gallo
    Department of Medical Genetics, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada
    Mech Ageing Dev 132:515-8. 2011
    ..We show that gei-7 is required for the longevity of the mitochondrial mutant clk-1. Our data suggest that only mitochondrial mutants that upregulate gei-7 can achieve longevity...
  4. pmc RNAi screen of DAF-16/FOXO target genes in C. elegans links pathogenesis and dauer formation
    Victor L Jensen
    Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 5:e15902. 2010
    ..We propose that dauer larva formation is a behavioral response to pathogens mediated by increased dauer pheromone production...
  5. pmc MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion
    Marco Gallo
    Department of Medical Genetics, The University of British Columbia, Vancouver, British Columbia, Canada
    PLoS ONE 6:e17827. 2011
    ..Our results suggest that controlling MISC-1/OGC function allows regulation of mitochondrial morphology and cell survival decisions by the metabolic needs of the cell...
  6. pmc Antagonistic Smad transcription factors control the dauer/non-dauer switch in C. elegans
    DonHa Park
    Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T1Z4, Canada
    Development 137:477-85. 2010
    ..In the adult, DAF-8 downregulates lag-2 expression in the distal tip cells, thus promoting germ line meiosis. This function does not involve DAF-3, thereby avoiding the feedback loop that functions in the dauer switch...