Research Topics
| R PadwalSummaryAffiliation: University of Alberta Country: Canada Publications
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Detail Information
Publications
Characteristics of patients undergoing bariatric surgery in CanadaRaj S Padwal
Division of General Internal Medicine, University of Alberta Hospital, Edmonton, Canada
Obes Res 13:2052-4. 2005..The characteristics of patients undergoing bariatric procedures outside of clinical studies and on a national level have not previously been reported...
Health status, quality of life, and satisfaction of patients awaiting multidisciplinary bariatric careRaj S Padwal
Department of Medicine, University of Alberta, 2F1, 26 Walter C, Mackenzie Health Sciences Centre, 8440 112th Street, Edmonton, AB T6G 2B7, Canada
BMC Health Serv Res 12:139. 2012..abstract:..
A systematic review on the effect of sweeteners on glycemic response and clinically relevant outcomesNatasha Wiebe
Department of Medicine, 13 103 Clinical Sciences Building, University of Alberta, Edmonton, Alberta, T6G 2G3 Canada
BMC Med 9:123. 2011..The major metabolic complications of obesity and type 2 diabetes may be prevented and managed with dietary modification. The use of sweeteners that provide little or no calories may help to achieve this objective...
The preventing recurrent vascular events and neurological worsening through intensive organized case-management (PREVENTION) trial protocol [clinicaltrials.gov identifier: NCT00931788]Finlay A McAlister
Division of General Internal Medicine, University of Alberta Hospital, 8440 112 Street, Edmonton, Canada
Implement Sci 5:27. 2010..If our intervention improves the provision of secondary prevention therapies in these patients, the clinical (and financial) implications will be enormous...
Using the Edmonton obesity staging system to predict mortality in a population-representative cohort of people with overweight and obesityRaj S Padwal
Department of Medicine, University of Alberta, Edmonton, Alta
CMAJ 183:E1059-66. 2011..We examined the ability of the Edmonton obesity staging system, a 5-point ordinal classification system that considers comorbidity and functional status, in predicting mortality in a nationally representative US sample...
The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 1--blood pressure measurement, diagnosis and assessment of riskRaj S Padwal
Division of General Internal Medicine, University of Alberta, Edmonton, Canada
Can J Cardiol 25:279-86. 2009..To provide updated, evidence-based recommendations for the diagnosis and assessment of adults with hypertension...
Bariatric surgery: a systematic review of the clinical and economic evidenceRaj Padwal
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
J Gen Intern Med 26:1183-94. 2011..Use of bariatric surgery for severe obesity has increased dramatically...
A systematic review of drug absorption following bariatric surgery and its theoretical implicationsR Padwal
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Obes Rev 11:41-50. 2010..Individual dose-adjustment and therapeutic monitoring may be required. Rigorously conducted controlled studies are needed to evaluate the effect of modern bariatric procedures on drug absorption...
Contrave, a bupropion and naltrexone combination therapy for the potential treatment of obesityRaj Padwal
Department of Medicine, University of Alberta Hospital, 2F1 26 Walter C Mackenzie Health Sciences Centre, Edmonton, AB T6G 2B7, Canada
Curr Opin Investig Drugs 10:1117-25. 2009..Assuming that the results of the Contrave phase III clinical program reaffirm the efficacy and safety of the drug combination, this agent could be approved and launched to become a market leader in the anti-obesity therapeutic arena...
The Alberta population-based prospective evaluation of the quality of life outcomes and economic impact of bariatric surgery (APPLES) study: background, design and rationaleRaj S Padwal
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
BMC Health Serv Res 10:284. 2010..We hypothesize that lower indirect, out of pocket and productivity costs will offset increased direct health-care costs resulting in lower total costs for bariatric surgery...
The 2008 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 1 - blood pressure measurement, diagnosis and assessment of riskRaj J Padwal
Division of General Internal Medicine, University of Alberta, Edmonton, Canada
Can J Cardiol 24:455-63. 2008..To provide updated, evidence-based recommendations for the diagnosis and assessment of adults with hypertension...
Cetilistat, a new lipase inhibitor for the treatment of obesityRaj Padwal
University of Alberta, Clinical Pharmacology and Internal Medicine, 8440 112th Street, Edmonton, T6G 2B7, Canada
Curr Opin Investig Drugs 9:414-21. 2008..It is also under investigation for the potential management of type 2 diabetes. Several phase II clinical trials for obesity have been completed. Phase III trials were in preparation at the time of publication...
The 2007 Canadian Hypertension Education Program recommendations for the management of hypertension: part 1- blood pressure measurement, diagnosis and assessment of riskRaj S Padwal
Division of General Internal Medicine, University of Alberta, Edmonton, Alberta
Can J Cardiol 23:529-38. 2007..To provide updated, evidence-based recommendations for the diagnosis and assessment of adults with hypertension...
Long-term persistence with orlistat and sibutramine in a population-based cohortR Padwal
Division of General Internal Medicine, Walter C Mackenzie Health Sciences Center, University of Alberta Hospital, 8440 112th Street, Edmonton, Alberta, Canada
Int J Obes (Lond) 31:1567-70. 2007..The objective of this study was to determine the long-term persistence with orlistat and sibutramine therapy outside a clinical trial setting...
Drug treatments for obesity: orlistat, sibutramine, and rimonabantRaj S Padwal
Department of Medicine, University of Alberta Hospital, Edmonton, AB, Canada
Lancet 369:71-7. 2007..Only then can patients and their physicians be confident that the putative benefits of such drugs outweigh their risks and costs...
Trends in obesity and overweight-related office visits and drug prescriptions in Canada, 1998 to 2004Raj S Padwal
Division of General Internal Medicine, 2E3 22 Walter C Mackenzie Health Sciences Center, University of Alberta Hospital, 8440 112th Street, Edmonton, AB, Canada, T6G 2B7
Obes Res 13:1905-8. 2005..This study sought to determine whether this rise in prevalence and awareness has resulted in an increased frequency of obesity and overweight-related office visits or antiobesity drug prescriptions over the past 5 years...
A systematic review of drug therapy to delay or prevent type 2 diabetesRaj Padwal
Department of Medicine, 2E3 22 Walter C Mackenzie HSC, University of Alberta Hospital, 8440 112th St, Edmonton, AB, Canada, T6G 2B7
Diabetes Care 28:736-44. 2005..To systematically review the evidence for the prevention of type 2 diabetes by pharmacological therapies...
Antihypertensive therapy and incidence of type 2 diabetes in an elderly cohortRaj Padwal
Division of General Internal Medicine, University of Alberta, Edmonton, Canada
Diabetes Care 27:2458-63. 2004..The aim of this study was to determine whether the incidence of type 2 diabetes differed among elderly users of four major antihypertensive drug classes...
Antihypertensive therapy and incidence of type 2 diabetes: a systematic reviewRaj Padwal
Division of General Internal Medicine, University of Alberta, Edmonton, Alberta, Canada
Diabetes Care 27:247-55. 2004..To systematically review the available evidence examining the effects of the major antihypertensive drug classes on the incidence of type 2 diabetes...
Prevention of cardiovascular disease: obesity, diabetes and the metabolic syndromeRaj S Padwal
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Can J Cardiol 26:18C-20C. 2010..Future efforts will need to focus on these factors and pansocietal solutions will be required if success in reversing the population-wide weight increases that have occurred over the past several decades is to be achieved...
The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 2--therapyNadia A Khan
Division of General Internal Medicine, University of British Columbia, Vancouver, Canada
Can J Cardiol 25:287-98. 2009..To update the evidence-based recommendations for the prevention and management of hypertension in adults for 2009...
Association between obesity and health-related quality of life in patients with coronary artery diseaseA Oreopoulos
Department of Clinical Epidemiology, School of Public Health, University of Alberta, Edmonton, Alberta, Canada
Int J Obes (Lond) 34:1434-41. 2010..Our objective was to determine whether this counterintuitive relationship extends to health-related quality of life (HRQOL) outcomes...
Obesity is a sign - over-eating is a symptom: an aetiological framework for the assessment and management of obesityA M Sharma
Department of Medicine, University of Alberta, Royal Alexandra Hospital, Edmonton, AB AB T5H 3V9, Canada
Obes Rev 11:362-70. 2010....
Bariatric surgery: a systematic review and network meta-analysis of randomized trialsR Padwal
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Obes Rev 12:602-21. 2011..Compared with Roux-en-Y gastric bypass, adjustable gastric banding has lower weight loss efficacy, but also leads to fewer serious adverse effects...
Long-term pharmacotherapy for overweight and obesity: a systematic review and meta-analysis of randomized controlled trialsR Padwal
Division of Internal Medicine, University of Alberta Hospital, 2E3 Walter C Mackenzie Health Sciences Centre, Edmonton, AB, Canada
Int J Obes Relat Metab Disord 27:1437-46. 2003..Safe and effective strategies to curb rising obesity prevalence rates are urgently needed and medications may play a more prominent role in future therapeutic regimens...
Statins and outcomes in patients admitted to hospital with community acquired pneumonia: population based prospective cohort studySumit R Majumdar
Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada
BMJ 333:999. 2006....
Association between direct measures of body composition and prognostic factors in chronic heart failureAntigone Oreopoulos
School of Public Health, University of Alberta, Edmonton, Alberta, Canada
Mayo Clin Proc 85:609-17. 2010....
Cancer screening among the overweight and obese in CanadaRebecca S Mitchell
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Am J Prev Med 35:127-32. 2008..S. studies have reported the reduced use of cancer screening among these subjects. We sought to analyze the relationship between overweight/obesity and cancer screening practices using population-based Canadian data...
