Research TopicsGenomes and GenesSpecies | David A OwenSummaryAffiliation: University of British Columbia Country: Canada Publications
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Publications
Gastritis and carditisDavid A Owen
University of British Columbia, Vancouver, British Columbia, Canada
Mod Pathol 16:325-41. 2003..Carditis is a controversial topic: currently opinions are divided as to whether it is the result of gastroesophageal reflux or a proximal extension of H. pylori infection from the remainder of the stomach...
Periodic acid-schiff is superior to hematoxylin and eosin for screening prophylactic gastrectomies from CDH1 mutation carriersAnna F Lee
Department of Pathology and Laboratory Medicine, University of British Columbia and Vancouver General Hospital, Vancouver, BC, Canada
Am J Surg Pathol 34:1007-13. 2010..Thus, doing PAS staining instead of H&E on CDH1 mutation-positive prophylactic gastrectomy specimens may increase the detection rate of adenocarcinoma while reducing screening time...
Predictive value of lymph node and tumor matrix metalloproteinase expression in the analysis of metastatic periampullary tumorsGregory J McKenna
Department of Surgery, Vancouver Hospital and Health Sciences Centre, University of British Columbia, Vancouver, British Columbia, Canada
J Surg Oncol 90:239-46. 2005..This prognostic information may be of use in patients when planning future adjuvant therapies...
Tumor expression of integrin-linked kinase (ILK) correlates with the expression of the E-cadherin repressor snail: an immunohistochemical study in ductal pancreatic adenocarcinomaDavid F Schaeffer
Department of Pathology, The University of British Columbia, 855 West 12th Avenue, Vancouver, BC, V5Z 1M9, Canada
Virchows Arch 456:261-8. 2010..The increase in expression of the E-cadherin repressor Snail, as well as the related increase in the ILK expression, may point towards an ILK-mediated induction, opening possible avenues for targeted drug therapy...
Model of the early development of diffuse gastric cancer in E-cadherin mutation carriers and its implications for patient screeningFatima Carneiro
Institute of Molecular Pathology and Immunology of the University of Porto IPATIMUP, Porto, Portugal
J Pathol 203:681-7. 2004..An in situ precursor of signet ring carcinoma was identified and a model for neoplastic progression in the setting of HDGC is proposed...
Chronic advanced gastric cancer: clinicopathologic analysis of survival dataWalter C MacDonald
Division of Medical Oncology, Vancouver Centre, British Columbia Cancer Agency and University of British Columbia, Vancouver, Canada V5Z 4E6
Hum Pathol 39:641-9. 2008..The use of pathologic features in addition to the standard Lauren classification better separated the chronic cancers from the cured cancers and showed differences in behavior between histologic types...
